• Korean journal of applied entomology
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• v.61 no.2
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• pp.283-288
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• 2022

The study aimed to investigate the psychological effect of the emotional insect-assisted healing program on the stress experienced by 43 children in a community child center. Silkworm (Bombyx mori [Linnaeus]) was used in the healing programs, and the stress was measured using salivary alpha-amylase levels. Saliva samples and a survey on insect preference were collected before and after the healing programs, respectively. After the program, the satisfaction score for participation was evaluated. Results indicate that the emotional insect-assisted healing programs led to statistically significant lowering of salivary alpha-amylase levels and increased the preference for insects. The children's satisfaction in the healing program activities using silkworms was 4.23 points out of 5.

• Perspectives in Nursing Science
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• v.2 no.1
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• pp.48-60
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• 2005

The relationship of psychological stress to human health is of interest to health care providers and researchers in the field of psychoneuroimmunology. The effect of stress on wound healing is a sub-component of study within the larger context, with relevance to both wounds that are acute and chronic in nature. Data from several studies that explore the influence of stress on events early in the trajectory of wound healing suggest that activation of both the sympathetic nervous system and the hypothalamic-pituitary-adrenal axis are involved. There is consistent evidence that psychological stress is associated with dysregulation of immune and other responses to tissue injury that are required for healing and also to the final wound healing result. Current data pertinent to psychological stress and its wound healing consequences is reviewed and a biopsychosocial framework for future studies in this area is suggested and described.

• International Journal of Advanced Culture Technology
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• v.10 no.2
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• pp.53-61
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• 2022

This study suggested the environmental components for open space in a healing environment based on the social support approach for integrating and enhancing users' activities and interactions. The physical environments of the open space in healing facilities should be suggested by social support design and support the interactions of various users. Particularly architectural environment conditions should reinforce the contribution to the revitalization of medical facilities based on improving the healing effect of patients through mutual exchange of users. The open space environment conditions influence users' healing process with physical design factors and users' interactions, and the flexible environments based on the social support that is crucial for circulation and mutual exchange of users. The open space transformation, integration of technology, and wayfinding system with color and signage also allow users to improve the space experience and easy access. The environmental components of open space design should include easy access for user inflow, flexible layout for comfort, access to outdoor spaces, integration of warm color schemes for relaxation, personalization of spaces with artwork, and visual interest through the use of textures and materials.

• Journal of the Korea Fashion and Costume Design Association
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• v.19 no.2
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• pp.15-28
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• 2017

Today, modern people are exposed to various environmental pollutants such as harmful substances and stress, which can compromise health. Therefore, a healing culture that seeks to enjoy human life based on the healing of body and mind is attracting great attention. The purpose of this study is to develop environmentally friendly natural dyeing considering a healing concept with four elements: color, dye, material, and pattern. The research methods and scope are based on a theoretical review of healing and research on the literature of bedding related to natural dyes, national and international books, the Internet, etc., and naturally dyed bedding. This paper presents actual production research. The results of this study are as follows. First, the elements of color, dyeing, material and pattern were developed through the process of a bedding design development model that applies a healing concept and can be commercialized as a healing bedding product. Second, a healing color proposal was expressed in an intermediate color system of pink, ocher, lavender, and indigo colors for emotional stability, warmth, calmness, comfort and softness. Third, eco-friendly bedding using natural dyes with medicinal efficacy can obtain the healing effect of the natural treatment method, which can aid healthy sleep. Fourth, the pattern used in the bedclothes was a motif of Sarasa embroidery, flower embroidery, ribbon embroidery, and wave quilting motifs to provide psychological stability as a healing concept in the sleeping environment. The natural healing bedding with the healing concept proposed in this study has natural treatment that is beneficial to human health and the development of bedding with natural dyes will lead to an increase of demand for the sleeping environment.

• Journal of the Korean Recycled Construction Resources Institute
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• v.10 no.4
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• pp.600-608
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• 2022

This study investigates the effect of layered double hydroxide (LDH) on the healing performance of self-healing concrete by assessing the chloride penetration resistance of self-healing cement mortars using electrical chloride ion migration-diffusion test. Test results show that both mortars containing healing materials only and mortars containing healing materials and Ca-Al LDH together mostly had higher migration-diffusion coefficients right after cracking, but the migration-diffusion coefficients decreased more than that of OPC with increasing healing ages, and thus, they yielded higher healing capacities than OPC. Also, mortars containing Ca-Al LDH together with healing materials showed higher reduction of their migration-diffusion coefficients, and thus, higher healing capacities than mortars containing healing materials only. This suggests that as the self-healing product increases on the crack surface, the binding of chloride ions by LDH inside the crack increases.

• Biomolecules & Therapeutics
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• v.18 no.3
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• pp.329-335
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• 2010

The extract from Hydnocarpi Semen (HS) has been used to treat leprosy and its anti-inflammatory activity has been reported. However, the effect of HS on the treatment of diabetic or peripheral ulcer is not well known. We therefore examined its wound healing effects on ulcer area in diabetic mice. GC and GC/MS analysis with the total extract of HS show that the main constituents of the extract are chaulmoogric acid, hydnocarpic acid, and gorlic acid. Whereas HS showed wound healing effect in diabetic ulcer, there was no hypoglycemic effect in diabetic mice. The treatment of HS extract significantly decreased the level of total WBC and neutrophils in mice compared to control mice. Cutting ulcer was induced by the round-shaped punch on the backside of diabetic mice and the extract of HS was given orally or topically. The wound area score significantly decreased after treatment of HS at dose of 50 mg/kg. The treatment of HS also induced the activation of macrophages and increased the production of IL-12 and TNF-$\alpha$ in macrophages, indicating that the wound healing by HS extract is associated with the inflammatory effect via the activation of macrophages. Our results suggest that HS extract can be a new therapeutic candidate for treatment of diabetic ulcer.

• Journal of The Korea Institute of Healthcare Architecture
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• v.20 no.3
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• pp.7-15
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• 2014

Purpose: This study is to propose direction for healing environment design in hospital architecture considering the characteristics of elderly patients. The primary goal of a public hospital is providing cheap health care and quality service chance to the underprivileged and elderly in the dead zone. Compared to the rapid increase of the aged population and chronic diseases, Ministry of Health & Welfare is currently planning model of health promotion hospital in development plans of local based public hospital. Due to the increased elderly medical expenses, elderly patients' high utilization is considered. Methods: The literature on the design factors of healing environments were investigated. based on this, analyzed drawings of surveyed hospitals ward in architectural characteristics and observe and evaluate directly healing environment design through field surveys. Results: The design of hospital environment affects patient's therapeutic effect. There is no any official formula for hospital design but environment that architect create could be a big part of the healing process. To increase the quality of the environment, apply the characteristic factors and harmonize well as a human-centered healing environment. Implications: Healing environment design for the elderly is first necessary condition due to high proportion of elderly patients.

• Restorative Dentistry and Endodontics
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• v.41 no.4
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• pp.262-270
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• 2016

Objectives: This study aimed to evaluate the healing rate of non-surgical endodontic treatment between C-shaped and non-C-shaped mandibular second molars. Materials and Methods: Clinical records and radiological images of patients who had undergone endodontic treatment on mandibular second molars between 2007 and 2014 were screened. The periapical index scoring system was applied to compare healing outcomes. Information about preoperative and postoperative factors as well as the demographic data of the patients was acquired and evaluated using chi-square and multinomial logistic regression tests. Results: The total healing rate was 68.4%. Healing rates for the mandibular second molar were 70.9% in C-shaped canals (n = 79) and 66.6% in non-C-shaped ones (n = 117). The difference was not statistically significant. Conclusions: The presence of a C-shaped canal in the mandibular second molar did not have a significantly negative effect on healing after treatment. Instead, proper pulpal diagnosis and final restoration were indicated as having significantly greater influence on the healing outcomes of C-shaped and non-C-shaped canals, respectively.

• Archives of Plastic Surgery
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• v.39 no.2
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• pp.106-112
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• 2012

Background : Complicated diabetic patients show impaired, delayed wound healing caused by multiple factors. A study on wound healing showed that platelet-rich plasma (PRP) was effective in normal tissue regeneration. Nonetheless, there is no evidence that when platelet-rich plasma is applied to diabetic wounds, it normalizes the diabetic wound healing process. In this study, we have analyzed matrix metalloproteinase (MMP)-2, MMP-9 expression to investigate the effect of PRP on diabetic wounds. Methods : Twenty-four-week-old male Otsuka Long-Evans Tokushima Fatty rats were provided by the Tokushima Research Institute. At 50 weeks, wounds were arranged in two sites on the lateral paraspinal areas. Each wound was treated with PRP gel and physiologic saline gauze. To determine the expression of MMP-2, MMP-9, which was chosen as a marker of wound healing, reverse transcription polymerase chain reaction (RT-PCR) was performed and local distribution and expression of MMP-2, MMP-9 was also observed throughout the immunohistochemical staining. Results : RT-PCR and the immunohistochemical study showed that the levels of MMP-2, MMP-9 mRNA expression in PRP applied tissues were higher than MMP-2, MMP-9 mRNA expression in saline-applied tissues. MMP-9 mRNA expression in wounds of diabetic rats decreased after healing began to occur. But no statistical differences were detected on the basis of body weight or fasting blood glucose levels. Conclusions : This study could indicate the extracellular matrix-regulating effect observed with PRP. Our results of the acceleration of wound healing events by PRP under hyperglycemic conditions might be a useful clue for future clinical treatment for diabetic wounds.

• Polymer(Korea)
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• v.37 no.6
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• pp.802-808
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• 2013

The purpose of this study was to develop an aloin-loaded wound dressing with an enhanced healing effect. The cross-linked hydrogel films were prepared with poly(vinyl alcohol) (PVA) and carboxyl methyl cellulose (CMC) using a freeze-thawing (F-T) method. Their gel properties, release of drug, in vivo wound healing effect and histopathology were then evaluated. In the wound healing test, this aloin loaded PVA/CMC hydrogel showed faster healing of the wound made in rat dorsum than the aloin carbomer 934 gel or the control (carbomer 934 gel) due to phytochemical activity of aloin and moisture of CMC. In conclusion, the aloin-loaded wound dressing composed of 5% PVA, 5% CMC and 0.125% aloin is a potential wound dressing with enhanced wound healing effect.