• Journal of the Korean Electrochemical Society
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• v.25 no.2
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• pp.51-68
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• 2022

Although lithium metal batteries have a high energy density, experimental skills capable of solving lots of problems induced by dendrite such as short circuit, low coulomb efficiency, capacity loss, and cycle performance are still only in academic research stage. In this paper, research cases for dendrite growth inhibition on lithium metal electrode were classified into four types: flexible SEI (solid electrolyte interface) layer responding to volume expansion of lithium metal electrode, SEI supporting layer to inhibit dendrite growth physically, SHES (self-healing electrostatic shield) mechanism to adjust lithium growth by leading uniform diffusion of Li⁺ ions, and finally micro-patterning to induce uniform deposition of lithium. We hope to advance the practical use of lithium metal electrode by analyzing pros and cons of this classification.

• Journal of Adhesion and Interface
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• v.23 no.1
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• pp.8-16
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• 2022

In this study, self-healable waterborne polyurethane (SH-WPU) as shoes and coating materials with self-healable disulfide functionalities was synthesized by mixing polyether polyol to impart excellent durability and heat resistance and polycarbonate polyol to impart excellent mechanical properties. The synthesized SH-WPU was characterized by fourier transform-infrared spectroscopy (FT-IR), and physical and self-healing properties were confirmed through universal testing machine (UTM) and scanning electron microscope (SEM) measurements. Tensile strength and hardness were increased and elongation was decreased by using polycarbonate polyol. In addition, as a result of comparison of thermal properties, thermal stability has been increased as the content of polycarbonate polyol increased. The healing efficiency showed the highest efficiency when poly(tetramethylene ether)glycol : polycarbonate polyol = 0.75 : 0.25, and it was confirmed that the damaged part was healed through surface observation using a microscope and SEM.

• Journal of Ginseng Research
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• v.42 no.4
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• pp.524-531
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• 2018

Background: Fermented black ginseng (FBG) is produced through several cycles of steam treatment of raw ginseng, at which point its color turns black. During this process, the original ginsenoside components of raw ginseng (e.g., Re, Rg1, Rb1, Rc, and Rb2) are altered, and less-polar ginsenosides are generated (e.g., Rg3, Rg5, Rk1, and Rh4). The aim of this study was to determine the effect of FBG on wound healing. Methods: The effects of FBG on tube formation and on scratch wound healing were measured using human umbilical vein endothelial cells (HUVECs) and HaCaT cells, respectively. Protein phosphorylation of mitogen-activated protein kinase was evaluated via Western blotting. Finally, the wound-healing effects of FBG were assessed using an experimental cutaneous wounds model in mice. Results and Conclusion: The results showed that FBG enhanced the tube formation in HUVECs and migration in HaCaT cells. Western blot analysis revealed that FBG stimulated the phosphorylation of p38 and extracellular signal-regulated kinase in HaCaT cells. Moreover, mice treated with $25{\mu}g/mL$ of FBG exhibited faster wound closure than the control mice did in the experimental cutaneous wounds model in mice.

• Journal of Periodontal and Implant Science
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• v.49 no.1
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• pp.25-38
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• 2019

Purpose: This study evaluated differences in bone healing and remodeling among 3 implants with different surfaces: sandblasting and large-grit acid etching (SLA; IS-III $Active^{(R)}$), SLA with hydroxyapatite nanocoating (IS-III $Bioactive^{(R)}$), and SLA stored in sodium chloride solution ($SLActive^{(R)}$). Methods: The mandibular second, third, and fourth premolars of 9 dogs were extracted. After 4 weeks, 9 dogs with edentulous alveolar ridges underwent surgical placement of 3 implants bilaterally and were allowed to heal for 2, 4, or 12 weeks. Histologic and histomorphometric analyses were performed on 54 stained slides based on the following parameters: vertical marginal bone loss at the buccal and lingual aspects of the implant (b-MBL and l-MBL, respectively), mineralized bone-to-implant contact (mBIC), osteoid-to-implant contact (OIC), total bone-to-implant contact (tBIC), mineralized bone area fraction occupied (mBAFO), osteoid area fraction occupied (OAFO), and total bone area fraction occupied (tBAFO) in the threads of the region of interest. Two-way analysis of variance (3 types of implant $surface{\times}3$ healing time periods) and additional analyses for simple effects were performed. Results: Statistically significant differences were observed across the implant surfaces for OIC, mBIC, tBIC, OAFO, and tBAFO. Statistically significant differences were observed over time for l-MBL, mBIC, tBIC, mBAFO, and tBAFO. In addition, an interaction effect between the implant surface and the healing time period was observed for mBIC, tBIC, and mBAFO. Conclusions: Our results suggest that implant surface wettability facilitates bone healing dynamics, which could be attributed to the improvement of early osseointegration. In addition, osteoblasts might become more activated with the use of HA-coated surface implants than with hydrophobic surface implants in the remodeling phase.

• Proceedings of the Korea Institute of Convergence Signal Processing
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• 2001.06a
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• pp.81-84
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• 2001

A signal path control switch has been designed and implemented with AT&T 0.5${\mu}{\textrm}{m}$ CMOS ORCA FPGA. This device controls the path of digital signals in SDH-based transmission system. The proposed switch is suitable for self-healing operation which protects against transmission network failure. The self-healing operation of the switch is effectively done by the reconfigurable information stored in the registers of the switch. This device consists of eight subparts such west-east transmitting parts, west-east receiving parts, add-drop control parts, AIS control Part, and CPU interface part. The device is capable to a ring network as well as a linear network.

• Journal of Korea Game Society
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• v.19 no.4
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• pp.109-118
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• 2019

This paper shows the need to study the commercialized color book game screen composition and manipulation interface type in order to enhance the utilization of the serious game mobile coloring book game, which is utilized from the learning of color sense in modern people and children to the hobby life of adults or old people. For the healing of modern people, we are going to look at the design configuration of game screen interfaces in simple and fun mobile coloring book games, and propose a new way to improve interface design that improves uncomfortable design by organizing and analyzing basic interface UI design types.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.20 no.3
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• pp.284-291
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• 2011

Numerical experiments on biological interfacial layer, DEJ by finite element software ABAQUS have been conducted to study its fracture behavior including crack bridging / arresting characteristics in the model. Crack growth simulation has been carried out by numerical tool, XFEM, devoted to study cracks and discontinuities. The fracture toughness of DEJ has been estimated before and after crack bridging. The implications of bridging in numerical study of fracture behavior of DEJ-like biological interface have been discussed. It has been observed that the results provided by the numerical studies without proper accommodation of bridging phenomenon can mislead. This study can be helpful for understanding the DEJ-like biological interface in terms of its fracture toughness, an important material characteristics. This property of the material is an important measure that has to be taken care during design and manufacturing processes.

• The Journal of Korean Academy of Prosthodontics
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• v.29 no.3
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• pp.55-74
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• 1991

The purpose of this study was to investigate the influence of early functional load around osseointegrated titanium implants. 24 titanium plasma spray coated implants (ITI HS-type) were placed into the previously extracted site in the mandible of six adult dogs. The implants were divided into three groups : the control group was the implants without abutment during the experimental period; the experimental group I was loaded by connecting the contoured abutment after 6 weeks of healing; the experimental group II was loaded after 12 weeks of healing: and the mandibular second premolar and surrounding tissues were selected for natural tooth group to compare the implanted group. All dogs were injected intravenously tetracycline, alizarin red S, and calcein for bone labeling. After the experimental period of 18 weeks, the dogs were sacrificed and longitudinal sections of the bone-implant interface were cut and observed using light microscope, scanning electron microscope, and fluorescence microscope. The results of the study were as follows: 1. Light and scanning electron microscopically, all implant surfaces were well contact with bone tissue at the cortical layer, but some areas of cancellous bone were not contact directly. 2. Fluorescence microscopically, number and size of the new secondary osteons around the implant were increased than those of the natural tooth. 3. Fluorescence microscopically, linear and concentrical fluorescence was observed at or near the surface of all implants, and the bone formation and remodeling of the implants loaded after 6 week of healing were great, and unloaded implants were worst. 4. Fluorescence microscopically, endosteal bone formation was greater than periosteal bone formation at or near the implants. 5. Fluorescence microscopically, number and size of linear and concentric fluorescence was increased at the lingual side than the buccal side of the loaded implants. The result of the study indicate the possibility of the early load to the implant via a prosthesis.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.26 no.12C
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• pp.240-248
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• 2001

This paper describes the design of a space-division switch which can support a self-healing operation of 2-fiber bidirectional line switched ring in 2.5Gb/s SDH-based transmission system. The switch having a 1.25Gb/s throughput has been designed and implemented with COMPASS tool and 0.87$\mu\textrm{m}$ CMOS gate-array. The proposed switch is suitable for the quickly self-healing operations when a failure occurs in a 2-fiber bidirectional switched ring composed of ADM transmission systems. The switch is composed of an add/drop control part, a cross-point switch, a frame-phase aligner, processor interface and an unequipped data framer. The test results of the switch adapted to 2.SGb/s SDH-based transmission system, show immediate restoration when a failure occurs.

• Clinics in Shoulder and Elbow
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• v.26 no.2
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• pp.131-139
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• 2023

Background: Massive rotator cuff tears (RCTs) are complicated by muscle atrophy, fibrosis, and intramuscular fatty degeneration, which are associated with postoperative tendon-to-bone healing failure and poor clinical outcomes. We evaluated muscle and enthesis changes in large tears with or without suprascapular nerve (SN) injury in a rat model. Methods: Sixty-two adult Sprague-Dawley rats were divided into SN injury (+) and SN injury (-) groups (n=31 each), comprising tendon (supraspinatus [SSP]/infraspinatus [ISP]) and nerve resection and tendon resection only cases, respectively. Muscle weight measurement, histological evaluation, and biomechanical testing were performed 4, 8, and 12 weeks postoperatively. Ultrastructural analysis with block face imaging was performed 8 weeks postoperatively. Results: SSP/ISP muscles in the SN injury (+) group appeared atrophic, with increased fatty tissue and decreased muscle weight, compared to those in the control and SN injury (-) groups. Immunoreactivity was only positive in the SN injury (+) group. Myofibril arrangement irregularity and mitochondrial swelling severity, along with number of fatty cells, were higher in the SN injury (+) group than in the SN injury (-) group. The bone-tendon junction enthesis was firm in the SN injury (-) group; this was atrophic and thinner in the SN injury (+) group, with decreased cell density and immature fibrocartilage. Mechanically, the tendon-bone insertion was significantly weaker in the SN injury (+) group than in the control and SN injury (+) groups. Conclusions: In clinical settings, SN injury may cause severe fatty changes and inhibition of postoperative tendon healing in large RCTs. Level of evidence: Level Basic research, controlled laboratory study.