• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제22권2호
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• pp.15-23
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• 2016

Purpose: Planning space of the house is important as a universal place to relieve stress of contemporary people. Void space is easy to perform mental and cultural programs in aspect of affording the healing behavior. The "Interface" accommodates healing behaviors through mutual interchange between void space and solid space as the edge of the solid space around void space. This study presents a efficient theory of healing space through combining space theory with the Kitwood's theory of psychiatry used for the art therapy. Methods: Spatial elements based on Kitwood's theory converges towards 2 behavioral elements; Meditation(-), Sense of Community(+). Balancing with reciprocal complement between behaviors of passive and stable "Meditation(-)" and active and released "Sense of Community(+)" was analysed. Results: "Faciliation" can be used in combination with "Flow(+)" as active factor. "Validation" is combined with "Prospect(+,-)", and divides into 2 factor ; "Recognition-Refreshment(-)", "Reaction-Social Exchange(+)". "Holding" is combined with "Refuge(-)" as passive factor. Implications: This study established concept of spatial healing elements in connection with theory of Psychiatry about Alzheimer that is extreme situation of stress. This study is expected to enhance the validity and efficiency in analysis of healing space.

• 접착 및 계면
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• 제22권2호
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• pp.47-56
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• 2021

자기치유 소재를 이용하여 강판을 코팅하는 경우, 코팅 소재에 상처가 날 경우 스스로 상처를 치유하여 강판이 부식되는 것을 방지할 수 있다. 하지만 자기치유 과정에는 시간이 소요되며, 따라서 자기치유가 되기 전에 강판의 상처가 부식 될 수 있다. 본 연구에서는 가역적인 hindered urea bond(HUB)를 통하여 가교 결합을 형성하면서 동시에 부식 방지제로써 작용하는 DTBEDA를 이용하여 듀얼자기치유 메커니즘을 가지는 코팅 소재를 제조하였다. 또한 제조된 소재를 강판에 코팅하여 의료용 메스와 나노/마이크로 압입시험기를 통하여 스크래치에 대한 자기치유 성능을 확인하였으며, DTBEDA의 내부식성 효과를 전기화학 임피던스 분광법(EIS)을 통하여 분석하였다.

• 구강회복응용과학지
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• 제29권3호
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• pp.272-279
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• 2013

골치유 기간 중 임플란트-골 계면에서 일정 수준 이상의 미세동요가 발생하게 되면 임플란트의 골유착이 방해받게 되므로 임플란트 식립 후 초기 골반응에 관해 임플란트 안정성은 하나의 지표가 된다. 본 연구의 목적은 임플란트 식립 후 전향적인 연구를 통해 초기 임플란트 안정성 변화를 추적하여 골치유 양상을 추론하고자 하였다. 총 26명의 환자에게 식립된 30개의 임플란트를 대상으로 하악골에 1회법으로 식립 직후 1주 간격으로 12주간 공진주파수분석을 시행하여 초기 안정성의 변화를 구하였으며 식립 직후와 1개월 간격으로 변연골 흡수 정도를 방사선학적 방법으로 측정하였다. 식립 직후와 각 치유기간 동안의 ISQ값 비교에서 식립 4주에서 6주사이에 골질에 따른 차이를 보였으나(P<0.05), 6주 이후에는 골질군 간에는 임플란트 안정성 변화에 차이가 없었다(P>0.05). 방사선학적 검사에서는 변연골의 차이가 관찰기간내에 유의하게 변화하지 않았다(P>0.05). 임플란트 식립 후 초기 골치유과정은 골흡수과정에 연속적인 과정으로 4주 이후 바람직한 골치유과정이 진행됨을 공진주파수분석으로 관찰할 수 있었다.

• 접착 및 계면
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• 제19권1호
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• pp.30-35
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• 2018

• 제어로봇시스템학회논문지
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• 제11권12호
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• pp.1020-1026
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• 2005

In the era of ubiquitous computing, human-friendly man-machine interface is getting more attention due to its possibility to offer convenient services. For this, in this paper, we introduce a 'Half-Mirror Interface System (HMIS)' as a novel type of human-friendly man-machine interfaces. Basically, HMIS consists of half-mirror, USB-Webcam, microphone, 2ch-speaker, and high-speed processing unit. In our HMIS, two principal operation modes are selected by the existence of the user in front of it. The first one, 'mirror-mode', is activated when the user's face is detected via USB-Webcam. In this mode, HMIS provides three basic functions such as 1) make-up assistance by magnifying an interested facial component and TTS (Text-To-Speech) guide for appropriate make-up, 2) Daily weather information provider via WWW service, 3) Health monitoring/diagnosis service using Chinese medicine knowledge. The second one, 'display-mode' is designed to show decorative pictures, family photos, art paintings and so on. This mode is activated when the user's face is not detected for a time being. In display-mode, we also added a 'healing-window' function and 'healing-music player' function for user's psychological comfort and/or relaxation. All these functions are accessible by commercially available voice synthesis/recognition package.

• Journal of Periodontal and Implant Science
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• 제31권1호
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• pp.41-57
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• 2001

It is well known that the apposition of bone at implant surface would be influenced by the microstructure of titanium implants. The purpose of this study was to compare bone healing around the screw-shaped titanium implant with three different surface topographies in the canine mandibles by histological and biomechanical evaluation. All mandibular premolars of six mongrel dogs were extracted and implants were placed one month later. The pure titanium implants had different surface topographies: smooth and machined ($Steri-OSS^{(R)}$: Group II); sandblasted and acid-etched ($ITI^{(R)}$, SLA: Group III) surface. The fluorescent dyes were injected on the 2nd (calcein), 4th (oxytetracycline HCI) and 12th (alizarin red) weeks of healing. Dogs were sacrificed at 4 and 12 weeks after implantation. The decalcified and undecalcified specimens were prepared for histological and histo-metrical evaluation of implant-bone contact. Some specimens at 12 weeks after implantation were used for removal torque testing. Histologically, direct bone apposition to implant surface was found in all of the treated groups. More mature and dense bone was observed at the implant-bone interface at 12 weeks than that at 4 weeks after implantation. Under the fluorescent microscope, thick regular green fluorescent lines which mean early bone apposition were observed at the implant-bone interface in Group III, while yellow and red fluorescent areas were found at the implant-bone interface in Group I and II. The average implant-bone contact ratios at 4 weeks of healing were 54.3% in Group I, 57.7% in Group II and 66.2% in Group III. In Group I, implant-bone contact ratio was significantly lower than Group II and III(p<0.05). The average implant-to-bone contact ratios at 12 weeks after implantation were 64.3% in Group I, 66.7% in Group II and 71.2% in Group III. There was no significant difference among the three groups. In Group I and II, the implant-bone contact ratio at 12 weeks increased significantly in comparison to ratio at 4 weeks(p<0.05). The removal torque values at 12 weeks after implantation were 90.9 Ncm in Group I, 81.6 Ncm in Group II and 77.1 Ncm in Group III, which were significantly different(p<0.05). These results suggest that bone healing begin earlier and be better around the surface-treated implants compared to the smooth surface implants. The sandblasted and acid-etched implants showed the most favorable bone response among the three groups during the early healing stage and could reduce the waiting period prior to implant loading.

• Journal of Periodontal and Implant Science
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• 제25권2호
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• pp.418-437
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• 1995

The effect of the hydroxyapatite coatings on Titanium implants has been the subject of recent investigations. So far, the use of HA coating remains substantially controversial.This study was aimed to evaluate histologically the bone healing patterns around titanium plasm sprayed(TPS) amd HA-coated implant after implantation into the femur neck of ten adult dogs. After implantation, animals were sacrificed at the intervals of 2,4,6,8 and 12 weeks.The fluorescent dyes were injected on the postoperative 4th and 12th week into the animals supposed to be killed at the 12th week. The morphology and direction of new bone formation was similar in both TPS and HA-coated implants.There was a tendency toward more bone formation in the cortical bone area than in the cancellous bone area. Histologically,in the interface of the HA-coated implants, bone response and bone maturation was faster, compared to the TPS implants in the 2nd and 4th week. By fluorescent microscopy, new bone formation was active in the 4th week around both implants and was directed from the periosteum overlying cortical bone to the cancellous bone. These results suggest that the bone formation and maturation is faster during the early healing stage in the interface of the HA-coated implant and where the cortical bone quality is poor, HA coated implant is superior to the TPS implant in the early phase of new bone formation.

• Clinical Pain
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• 제19권2호
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• pp.59-63
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• 2020

Rotator cuff tear is often cited as a reason for shoulder pain and dysfunction in patients > 40 years of age. Surgical repair of rotator cuff tear is one of the most commonly performed orthopedic surgical procedures. Until now, the success rate of surgical repair for rotator cuff tear has not been satisfactory. Many factors influence the process of rotator cuff repair such as the presence of tendinosis and fatty infiltration, but the main factor is the difficulty in achieving healing at the tendon to bone interface. There is a clinical need for bioengineering approaches to promote regeneration of the native enthesis and reduce the poor outcomes after surgical repair. Toward this end, the design and fabrication of multiphasic or hierarchically structured scaffolds have received great attention. This manuscript deals with information on the tendon to bone interface and tries to find out why a multiphasic scaffold is necessary to reproduce it and considerations that need to be taken into to make an ideal scaffold.

• 대한의용생체공학회:의공학회지
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• 제26권2호
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• pp.101-110
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• 2005

Periosteum and periosteum-derived progenitor cells have demonstrated the potential for stimulative applications in repairs of various musculoskeletal tissues. It has been found that the periosteum contains mesenchymal progenitor cells capable of differentiating into either osteoblasts or chondrocytes depending on the culture conditions. Anatomically, the periosteum is a heterogeneous multi-layered membrane, consisting of an inner cambium and an outer fibrous layer. The present study was designed to elucidate the cellular phenotypic characteristics of cambium and fibrous layer cells in vitro, and to assess whether structural integrity of the tendon in the bone tunnel can be improved by periosteal augmentation of the tendon­bone interface. It was found the cells from each layer showed distinct phenotypic characteristics in a primary monolayer culture system. Specifically, the cambium cells demonstrated higher osteogenic characteristics (higher alkaline phosphatase and osteocalcin levels), as compared to the fibrous cells. Also in vivo animal model showed that a periosteal augmentation of a tendon graft could enhance the structural integrity of the tendon-bone interface, when the periosteum is placed between the tendon and bone interface with the cambium layer facing toward the bone. These findings suggest that extra care needs to be taken in order to identify and maintain the intrinsic phenotypes of the heterogeneous cell types within the periosteum. This will improve our understanding of periosteum in applications for musculoskeletal tissue repairs and tissue engineering.

• Advances in biomechanics and applications
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• 제1권2호
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• pp.95-109
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• 2014

Peri-acetabular bone ingrowth plays a crucial role in long-term stability of press-fit acetabular cups. A poor bone ingrowth often results in increased cup migration, leading to aseptic loosening of the implant. The rate of peri-prosthetic bone formation is also affected by the polar gap that may be introduced during implantation. Applying a mechano-regulatory tissue differentiation algorithm on a two-dimensional plane strain microscale model, representing implant-bone interface, the objectives of the study are to gain an insight into the process of peri-prosthetic tissue differentiation and to investigate its relationship with implant-bone relative displacement and size of the polar gap. Implant-bone relative displacement was found to have a considerable influence on bone healing and peri-acetabular bone ingrowth. An increase in implant-bone relative displacement from $20{\mu}m$ to $100{\mu}m$ resulted in an increase in fibrous tissue formation from 22% to 60% and reduction in bone formation from 70% to 38% within the polar gap. The increase in fibrous tissue formation and subsequent decrease in bone formation leads to weakening of the implant-bone interface strength. In comparison, the effect of polar gap on bone healing and peri-acetabular bone ingrowth was less pronounced. Polar gap up to 5 mm was found to be progressively filled with bone under favourable implant-bone relative displacements of $20{\mu}m$ along tangential and $20{\mu}m$ along normal directions. However, the average Young's modulus of the newly formed tissue layer reduced from 2200 MPa to 1200 MPa with an increase in polar gap from 0.5 mm to 5 mm, suggesting the formation of a low strength tissue for increased polar gap. Based on this study, it may be concluded that a polar gap less than 0.5 mm seems favourable for an increase in strength of the implant-bone interface.