• Physical Therapy Rehabilitation Science
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• v.7 no.4
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• pp.186-190
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• 2018

Objective: Deep neck flexor muscle endurance (DNFET) is important to cervical pain patients. However, there is no normative data of the DNFET hold time of Korean university students. The purpose of this study was to provide normative data and the reliability of the DNFET times of Korean university students and to compare the DNFET hold times between male and female subjects. Design: Cross-sectional study. Methods: The participants included 39 male and 39 female students with no cervical pain. Each DNFET was measured while the subjects kept their chin tucked in while in a supine (hook-lying) position and with the head lifted 2.5 cm off the bed. The DNFET was conducted on each subject twice and the mean values were obtained. After each measurement, the participants rested for 5 minutes. Inter-rater reliability was measured by intraclass correlation coefficient (ICC) by three separate evaluators. Results: The inter-rater reliability was good, showing an ICC (2,3) value = 0.785 (95% confidence interval, 0.370-0.942). The DNFET time scores for men and women were $25.14{\pm}9.96$ seconds and $15.23{\pm}6.10$ seconds, respectively, in which the time scores of the men were significantly longer compared to women (p<0.05). Conclusions: Asymptomatic men displayed higher DNFET scores than women. This study can help clinicians test cervical function of patients and set an interventional goal. These findings serve as a basis that insists Korean women to increase their amount of physical activity.

• Journal of The Korean Society of Integrative Medicine
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• v.8 no.4
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• pp.117-123
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• 2020

Purpose : VDT (visual display terminal syndrome) can affect individuals who monitor or who work or play using video screens, including those of smartphones. In general, headache symptoms from overuse of these screens can appear due to eye fatigue, muscle pain in the joints of wrists or fingers, and muscle pain in the neck or shoulders. Many studies in the literature have supported standards that seek to prevent these symptoms. The incidence of musculoskeletal diseases caused by the use of smartphones is expected to increase rapidly, particularly among children and young adults, and these diseases are expected to develop into a societal problem. Therefore, in this study we investigate whether tension headaches that develop from smartphone usage can affect forward neck posture, neck pain, and quality of life. Methods : A total of 93 students from University participated in this study. We divided participants into two groups, those with tension headaches (n = 25) and those without (n = 68) and took forward neck measurements. Headaches were classified according to criteria from the International Headache Society and involved bilateral headache position, quality of pressing or tightening pain, mild or moderate pain intensity, and none due to daily physical activity. We surveyed participants using the smartphone addiction diagnosis questionnaire, the Neck Disability Index (NDI), the Headache Impact Test (HIT-6), and the Quality of Life Questionnaire. Results : Although we found no significant differences in tension headaches due to smartphone addiction diagnosis (p = 0.25), SF-36 life quality assessment (p = 0.06), and cranio-vertebral angle (p = 0.07), we found significant differences from the HIT-6 and the NDI (p <.05). Conclusion : Tension headaches are not correlated with smartphone addiction, quality of life, and forward neck angle but do have a correlation with the degree of cervical dysfunction and the effects of the headaches.

• The Journal of the Korea Contents Association
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• v.21 no.3
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• pp.1-9
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• 2021

The hologram pyramid is an application of floating holograms, allowing the observer to see three-dimensional holograms from various angles without wearing wearable devices. Due to the low cost and ease of manufacturing, it has been used in a wide variety of fields as diverse as education, prototyping, showcase, and etc. But, when the observer looks at the hologram from the place where each side of the hologram pyramid is connected, the hologram looks cut and distorted. Also, the observer can see the only hologram of angles viewed head-on from each side. In this paper, we propose a method of generating a hologram image corresponding to the observer's gaze angle by tracking the observer's position and conducting reverse distortion. It provide a hologram of the angle viewed by the observer without cutting and distortion. In addition, the existing method and the proposed method were applied and compared in the hologram pyramid.

• Biomolecules & Therapeutics
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• v.30 no.1
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• pp.19-27
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• 2022

Epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase widely expressed in many cancers such as non-small cell lung cancer (NSCLC), pancreatic cancer, breast cancer, and head and neck cancer. Mutations such as L858R in exon 21, exon 19 truncation (Del19), exon 20 insertions, and others are responsible for aberrant activation of EGFR in NSCLC. First-generation EGFR tyrosine kinase inhibitors (TKIs) such as gefitinib and erlotinib have clinical benefits for EGFR-sensitive (L858R and Del19) NSCLC patients. However, after 10-12 months of treatment with these inhibitors, a secondary T790M mutation at the gatekeeper position in the kinase domain of EGFR was identified, which limited the clinical benefits. Second-generation EGFR irreversible inhibitors (afatinib and dacomitinib) were developed to overcome this T790M mutation. However, their lack of selectivity toward wild-type EGFR compromised their clinical benefits due to serious adverse events. Recently developed third-generation irreversible EGFR TKIs (osimertinib and lazertinib) are selective toward driving mutations and the T790M mutation, while sparing wild-type EGFR activity. The latest studies have concluded that their efficacy was also compromised by additional acquired mutations, including C797S, the key residue cysteine that forms covalent bonds with irreversible inhibitors. Because second- and third-generation EGFR TKIs are irreversible inhibitors, they are not effective against C797S containing EGFR triple mutations (Del19/T790M/C797S and L858R/T790M/C797S). Therefore, there is an urgent unmet medical need to develop next-generation EGFR TKIs that selectively inhibit EGFR triple mutations via a non-irreversible mechanism.

• Journal of the Korean Geosynthetics Society
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• v.21 no.3
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• pp.49-59
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• 2022

This study was conducted to find out the rational and appropriate design of drilled shaft. In other words, in order to find out the variation of ultimate bearing capacity according to the change in the support layer of drilled shaft, back analysis was performed using the bi-directional pile load test performed on drilled shaft. Based on the back-analyzed data, numerical analysis of the pile head load was performed, and the ultimate bearing capacity in the target ground was evaluated using the Davisson method. As a result of numerical analysis of one case where the end of the pile was seated on the top of the weathered rock layer, and three cases where the end of the pile was embedded at different locations in the weathered soil, it was found that sufficient ultimate bearing capacity was secured in all cases. In other words, the case where the end of the pile is seated on the top of the weathered rock layer, not embedded the weathered rock, and the drilled shaft embedded into the weathered soil also have sufficient bearing capacity, so it can be used as a support layer for drilled shaft.

• Journal of the Institute of Convergence Signal Processing
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• v.23 no.3
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• pp.150-159
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• 2022

This paper presents an implementation of detecting whether a helmet is worn and there is a fall accident through individual image analysis in real-time from extracting the image objects of several workers active in the industrial field. In order to detect image objects of workers, YOLO, a deep learning-based computer vision model, was used, and for whether a helmet is worn or not, the extracted images with 5,000 different helmet learning data images were applied. For whether a fall accident occurred, the position of the head was checked using the Pose real-time body tracking algorithm of Mediapipe, and the movement speed was calculated to determine whether the person fell. In addition, to give reliability to the result of a falling accident, a method to infer the posture of an object by obtaining the size of YOLO's bounding box was proposed and implemented. Finally, Telegram API Bot and Firebase DB server were implemented for notification service to administrators.

• Clinical Pain
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• v.18 no.2
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• pp.92-96
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• 2019

Torticollis is an abnormal, asymmetric head or neck position which usually caused by imbalance of paracervical muscles. The traumatic torticollis can be caused by following events; atlantoaxial rotatory subluxation, atlantoaxial dislocation, cervical vertebral fractures, and injury to the cervical musculature. Especially, acute traumatic atlantoaxial rotatory subluxation usually presents limitation of cervical range of motion without pain or neurologic deficit. We report a case of a 58 year-old man who developed the acute atlantoaxial rotatory subluxation right after the chiropractic therapy, which induced the limitation of cervical range of motion to 52.5% of normal range. The magnetic resonance image revealed the facture of the odontoid process and the partial injury in transverse ligaments of the atlas. He underwent intramuscular botulinum toxin injection and 10 days of continuous cervical traction 15 hours a day using a 5 kg weight. The range of the cervical motion restored up to 90.2% of normal range.

• Geomechanics and Engineering
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• v.36 no.6
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• pp.545-561
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• 2024

Piled raft foundation has become widely used in the recent years because it can increase bearing capacity of foundation with control settlement. The design for a piled raft in terms vertical load and lateral load need to understands contribution load behavior to raft and pile in piled raft foundation system. The load-bearing behavior of the piled raft, especially concerning lateral loads, is highly complex and challenge to analyze. The complex mechanism of piled rafts can be clarified by using three dimensional (3-D) Finite Element Method (FEM). Therefore, this paper focuses on free-standing head pile group, on-ground piled raft, and embedded raft for the piled raft foundation systems. The lateral resistant of piled raft foundation was investigated in terms of relationship between vertical load, lateral load and displacement, as well as the lateral load sharing of the raft. The results show that both vertical load and raft position significantly impact the lateral load capacity of the piled raft, especially when the vertical load increases and the raft embeds into the soil. On the same condition of vertical settlement and lateral displacement, piled raft experiences a substantial demonstrates a higher capacity for lateral load sharing compared to the on-ground raft. Ultimately, regarding design considerations, the piled raft can reliably support lateral loads while exhibiting behavior within the elastic range, in which it is safe to use.

• Journal of the Korean Society of Radiology
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• v.18 no.3
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• pp.301-307
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• 2024

The Study Evaluated Radiography Images using the Mastoid Process Axial Oblique Projection (Arcelin) imaging method for the Diagnosis of Pyramid Ridge, Mastoid Process, Mastoid Process air cells, Tympanum, Internal auditory and petrous in Supine Position. The subjective ROC (receiver operation characteristic) evaluation method was conducted on five Radiological technologists who have worked in the Image medical Department of University Hospitals for more than 8 years, and the Objective Evaluation, signal-to-noise Ratio (SNR), was evaluated and Analyzed. The Cronbach Alpha value was significantly higher at 0.816. In the Image ROC Evaluation Taken by Tilting the X-ray Tube 5°, 10°, 15° toward the leg by 10°, it Scored 34 points, and in the overall evaluation, the SNR scored high at 6,549. In Addition, In the Image Evaluation taken by Tilting the X-ray Tube 5°, 10°, and 15° toward the head, it Scored 32 points In the Image ROC Evaluation taken by tilting 5°, and in the Objective Evaluation, SNR received the highest score of 6,732.

• Journal of Radiation Protection and Research
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• v.49 no.2
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• pp.68-77
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• 2024

Background: Cone beam computed tomography (CBCT) is essential for correcting and verifying patient position before radiation therapy. However, it poses additional radiation exposure during CBCT scans. Therefore, this study aimed to evaluate radiological safety for the human body through dose assessment for CBCT. Materials and Methods: For CBCT dose assessment, the depth dose was evaluated using a cheese phantom, and the dose in the orbital area was evaluated using a human body phantom self-fabricated with a three-dimensional printer. Results and Discussion: The evaluation of radiation doses revealed maximum doses of 14.14 mGy and minimum doses of 6.12 mGy for pelvic imaging conditions. For chest imaging conditions, the maximum doses were 4.82 mGy, and the minimum doses were 2.35 mGy. Head imaging conditions showed maximum doses of 1.46 mGy and minimum doses of 0.39 mGy. The eyeball doses using a human body phantom model averaged at 2.11 mGy on the left and 2.19 mGy on the right. The depth dose ranged between 0.39 mGy and 14.14 mGy, depending on the change in depth for each imaging mode, and the average dose in the orbit area using a human body phantom was 2.15 mGy. Conclusion: Based on the experimental results, CBCT did not significantly affect the radiation dose. However, it is important to maintain a minimal radiation dose to optimize radiation protection following the as low as reasonable achievable principle.