• 한국토양비료학회지
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• 제14권4호
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• pp.185-189
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• 1982

습답(濕畓)의 저수요인(低收要因)을 구명(究明)하기 위(爲)하여 수분이동(水分移動) 방향(方向), 토양온도(土壤溫度) 및 산화환원전위(酸化還元電位)와 수도(水稻)의 생육(生育)과의 관계(關係)를 조사(調査)한 결과(結果)는 다음과 같다. 1. 곡간습답(谷間濕畓)에서는 지점(地点)에 따라 ${\Delta}Hp$의 변이(變異)가 크고 수도(水稻)의 작황(作況)도 차이(差異)가 심(甚)하였으나 평탄습답(平坦濕畓)에서는 지점간(地点間)의 ${\Delta}Hp$가 거의 균일(均一)하였다. 2. 물의 이동(移動) 방향(方向)에 따라 토양온도(土壤溫度) 및 수도생육(水稻生育)의 차이(差異)가 뚜렷하게 나타났다. 3. ${\Delta}Hp$와 수도생육(水稻生育) 및 수량간(收量間)에는 부(負)의 상관(相關)이 있어 지하수(地下水) 용출(湧出)이 많을수록 수량(收量) 감소(減少)가 심(甚)하였다. 4. 토양온도(土壤溫度)와 수도(水稻) 생육(生育) 및 수량(收量) 간(間)에는 정(正)의 상관(相關)이 있었으며, $16^{\circ}C$로 유지(維持)된 지점(地点)에서는 생육(生育)이 정지(停止)되어 수량(收量)이 전혀 없었다. 5. 토양(土壤)의 산화환원전위(酸化還元電位)는 ${\Delta}Hp$가 0의 부근(部近)에서 낮았고 물의 이동(移動)이 심(甚)한 곳에서는 높았다.

• 대한두경부종양학회지
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• 제35권2호
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• pp.61-65
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• 2019

Hamartomas are non-neoplastic malformations or congenital errors of tissue development. Hamartoma is composed by an excessive growth of mature tissue present in wrong proportions and abnormal arrangements. The lesion usually presents as a submucosal mass with ill-defined margins. Hamartoma occurs in all areas of the body, especially in the liver, spleen, kidney and lung. However, hamartoma is very rare in the head and neck. Presenting symptoms of hamartoma are typically vague and nonspecific. Treatment of hamartomas consists of adequate surgical excision. We present a 59 year-old male patient who presented with submental swelling. Malignancy could not be ruled out with preoperative radiologic examination, so surgical excision was planned. The mass was excised with transcervical approach. Histopathologic examination has confirmed the mass as a mucinous gland adenomatoid hamartoma.

• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.27-31
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• 2012

Objectives: Expression of vascular endothelial growth factor C (VEGF-C)and vascular endothelial growth factor feceptor-3 (VEGFR-3) in laryngeal squamous carcinoma and its relationship to lymph node metastasis were investigated. Methods: VEGF-C and VEGFR-3 gene expression in 30 cases of normal laryngeal mucosa tissue (NLM), primary laryngeal carcinoma cell carcinomas (PLC) and cervical lymph nodes (CLN) was examined by reverse transcription polymerase chain reaction (RT-PCR). Protein levels of VEGF-C expression were determined by immunohistochemical staining in 60 cases of PLC. Results: Expression of VEGF-C and VEGFR-3 different among NLM, PLC and CLN in the same patient. In PLC, expression was significantly higher in lymph node positive group than in the lymph node negative group and associated with histological grade of differentiation; Expression of VEGF-C and VEGFR-3 was not linked with age, sex, site or T stage. Conclusions: A close correlation was found between VEGF-C/VEGFR-3 expression and lymph node metastasis in PLC, suggesting a role in metastasis of laryngeal carcinomas.

• 대한두경부종양학회지
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• 제22권2호
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• pp.159-162
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• 2006

Trichilemmal carcinoma is a rare malignant neoplasm of the hair follicle from the outer root of the hair follicle sheath. This tumor can be misleading, and a false diagnosis of a squamous cell carcinoma. We report a case of trichilemmal carcinoma with a review of literature. The patient presented with an exophytic well circumscribed nodular mass on the left auricle, which was detected 6 months ago. Histopathologically, the tumor consisted of atypical clear cells which contained abundant glycogen. The tumor cells shows lobular growth pattern with necrosis, foci of trichilemmal keratinization and peripheral pallisading. Total excision and repair with full-thickness skin graft was done with minimal surgical morbidity. The patient has been free of recurrence or metastasis for 8 months.

• 임상이비인후과
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• 제29권2호
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• pp.259-263
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• 2018

There are many treatment options for the malignant melanoma. Wide excisional surgery is one of the most acceptable treatments for locoregional treatment. Depending on the pathologic classification, however, some other treatment option can be included such as chemotherapy, radiotherapy and immunotherapy as adjuvant treatment. Small cell type malignant melanoma is a rare variant of malignant melanoma. It is known that melanomas manifesting this morphology are invariably in vertical growth phase and have an aggressive course. The authors encountered small cell type malignant melanoma and would like to share the experience of successful treatment with surgery plus immunotherapy as one of adjuvant treatment options.

• 대한한방소아과학회지
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• 제17권1호
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• pp.157-168
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• 2003

The purpose of this study was to evaluate clinical characteristic and correlation with growth and weakness of children with excessive sweating. The study was progressed in children with excessive sweating who visited Dong-Eui Oriental Medical hospital from may to june, 2003. The results were as follows: 1. The growth numerical value on height and weight of children with excessive sweating was normal range ( height: p-value=0.089 >0.05, weight: p-value= 0.622>0.05). 2. In sweating region, head and neck 46.7%, forehead 23.3%, whole body 16.7%, back 10.0%, hand and foot 3.3%. In sweating time, sleeping 53.3%, acting 20.0%, uncertainty 20.0%, eating 3.3%, tense situation 3.3%. 3. In family history of excessive sweating, 'yes' was 65.2%, 'no' was 34.8%. 4. The growth numerical value on height did not concerned with sweating region and time, but in group in 75 marks, 'head and neck' was many. 5. The growth numerical value on weight have no concern with sweating region, but sweating time(F=3.312, p-value=0.026

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제28권1호
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• pp.7-15
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• 2002

The present study was carried out to evaluate the correlation of metastasis and prognostic factors in squamous cell carcinoma of head and neck. Examination was performed on a series of thirty-seven patients who were confirmed to squamous cell carcinoma and its lymphatic metastasis by pathologist. Correlations of metastasis and other factors such as angiogenesis, histologic grading, and p53 expression and ras oncogene were studied. The depth of tumors was around 1 to 27mm. Twenty cases were more than 10mm deep, of which seventeen cases were shown lymphatic metastasis. Total score of histologic grading including keratinization, nuclear atypia, growth pattern and intensity of inflammation was ranged from 5 to 10 points. Of these factors, nuclear atypia with intensity of inflammation, and nuclear atypia with growth pattern was correlated with nuclear atypia each. For angiogenesis, number of new-formed vessels were counted 13 to 58 each. Twenty-eight cases were shown to lymphatic metastasis. No correlation with histologic grading and lymphatic metastasis was found. The results of immunohistochemical staining for p53 and ras oncogene revealed that positive cases were 16 and 22, negative for 21 and 15 each. However, both were not correlated with histologic grading and lymphatic metastasis. These results were revealed that angiogenesis was not correlated with lymphatic metastasis of squamous cell carcinoma arising in head and neck. Nuclear atypia with intensity of inflammation and dysplasia with growth pattern were correlated with histologic grading, which suggested that more careful and adequate advice is needed for effective treatment.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.2217-2221
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• 2016

Vascular endothelial growth factor 2 (VEGFR2) was initially identified as a receptor of VEGF on endothelial cells with a role in regulating angiogenesis during organism development and tumorigenesis. Previously, in cancer tissue, VEGFR2 has been reported to be expressed in endothelial cells. In our research, we found that VEGFR2 was expressed not only in endothelial cells but also cancer cells in head and neck squamous cell carcinomas (HNSCCs). Knockdown of VEGFR2 in Hep2 cells could arrest the cell cycle in G0/G1, leading to a decrease in proliferation. We also present evidence that MAPK/ERK signal pathways and expression of CDK1 downstream of VEGFR2 might regulate proliferation and cell cycle arrest. Furthermore, we discovered that down-regulate VEGRF2 in Hep2 cells could significantly affect the invasion ability. Taken together, our data suggest that VEGFR2 might regulate proliferation and invasion in HNSCC cancer cells in vivo.

• 대한치과교정학회지
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• 제24권4호
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• pp.851-860
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• 1994

Before 1970, mandibular overgrowth was known as main cause of skeletal Class III malocclusion in growing children ; however, recent study reports that many skeletal Class III malocclusion patients also show maxillary deficiency. Since 1972, when Delaire re-accommodated Protraction Head Gear (P.H.G.), many researchers have reported that skeletal Class III discrepancies could be corrected through use of P.H.G., which induces anterior movement of maxilla and change in mandibular growth pattern into infero-posterior direction ; nevertheless, it is very difficult to predict resultant changes of orofacial region. The purpose of this study was to find out what treatment effect P.H.G. has on different study samples. Author divided 51 skeletal Class III malocclusion patients with maxillary deficiency who were treated with P.H.G. into different study groups depending on sex, treatment beginning age, intraoral appliance, and facial growth pattern. By doing so, following results were obtained. 1. Treatment beginning age and Sex Four age groups (5.8 to 8 year-old, 8 to 10 year-old, 10 to 12 year-old, 12 to 14 year-old) were compared, and no significant difference was observed. (p<0.05) There was no significant difference between the sex groups, either. (p<0.05). 2. Intraoral appliance Treatment effects of study groups that used R.P.E.(mean age of 10.2) and Labio-Lingual appliance(mean age of 8.9) were compared. There was no significant difference depending on the type of intraoral appliance that was used. (p<0.05) 3. Facial growth pattern 1) Amounts of SNB and ANB corrections were smaller in clockwise growth pattern group than those in normal or counterclockwise growth pattern group. (p<0.05) 2) Amounts of increase in Wits appraisal and mandibular plane angle were greater in counterclockwise growth pattern group than those in normal or clockwise growth pattern group. (p<0.05) 3)Amounts of increase in articular angle were greater in counter lockwise growth pattern group than those in clockwise growth pattern group. (p<0.05)

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제24권3호
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• pp.316-324
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• 2021

Purpose: The use of soy-based infant formula has increased widely in infants with cow's milk allergy (CMA). This study aimed to provide evidence on the growth pattern of CMA infants fed with soy-based infant formula in an Indonesian setting. Methods: A multi-site, intervention study was conducted among full-term and normal birth weight CMA infants. Within six months, the subjects were provided with a soy-based infant formula. Weight, height, and head circumference were measured at baseline, weeks 4, 8, 12, 16, 20, and 24. Adverse events were recorded by scoring atopic dermatitis and symptom-based clinical scores. Results: Based on the World Health Organization growth chart, we found that most of subjects had normal nutritional status for weight-for-age, length-for-age, weight-for-length, and head-circumference-for-age. There were statistically significant differences between baseline and end-line for weight-for-age, length-for-age, weight-for-length, and head circumference-for-age nutritional status. No allergic symptoms or intolerance toward soy formula were observed at the end of the intervention period. Conclusion: These results show that infants fed with soy-based infant formula have a normal pattern of growth.