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http://dx.doi.org/10.5223/pghn.2021.24.3.316

Growth Patterns of Indonesian Infants with Cow's Milk Allergy and Fed with Soy-Based Infant Formula  

Setiabudiawan, Budi (Department of Child Health, Faculty of Medicine, Universitas Padjadjaran)
Sitaresmi, Mei Neni (Department of Child Health, Faculty of Medicine, Universitas Gadjah Mada)
Sapartini, Gartika (Department of Child Health, Faculty of Medicine, Universitas Padjadjaran)
Sumadiono, Sumadiono (Department of Child Health, Faculty of Medicine, Universitas Gadjah Mada)
Citraresmi, Endah (Department of Child Health, Harapan Kita Child and Mother Hospital)
Sekartini, Rini (Department of Child Health, Faculty of Medicine, Universitas Indonesia)
Putra, Azwin Mengindra (Department of Child Health, Faculty of Medicine, Universitas Airlangga)
Jo, Juandy (Danone Nutricia Research)
Publication Information
Pediatric Gastroenterology, Hepatology & Nutrition / v.24, no.3, 2021 , pp. 316-324 More about this Journal
Abstract
Purpose: The use of soy-based infant formula has increased widely in infants with cow's milk allergy (CMA). This study aimed to provide evidence on the growth pattern of CMA infants fed with soy-based infant formula in an Indonesian setting. Methods: A multi-site, intervention study was conducted among full-term and normal birth weight CMA infants. Within six months, the subjects were provided with a soy-based infant formula. Weight, height, and head circumference were measured at baseline, weeks 4, 8, 12, 16, 20, and 24. Adverse events were recorded by scoring atopic dermatitis and symptom-based clinical scores. Results: Based on the World Health Organization growth chart, we found that most of subjects had normal nutritional status for weight-for-age, length-for-age, weight-for-length, and head-circumference-for-age. There were statistically significant differences between baseline and end-line for weight-for-age, length-for-age, weight-for-length, and head circumference-for-age nutritional status. No allergic symptoms or intolerance toward soy formula were observed at the end of the intervention period. Conclusion: These results show that infants fed with soy-based infant formula have a normal pattern of growth.
Keywords
Soy milk; Milk hypersensitivity; Body weight; Body height;
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