• Asian Pacific Journal of Cancer Prevention
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• 제15권24호
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• pp.10831-10836
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• 2015

This study was conducted to establish whether the preoperative platelet to lymphocyte ratio (PLR) is predictive of survival of women with ovarian clear cell carcinoma (OCCC). A PLR > 300 was deemed elevated. Progression-free survival (PFS) was estimated using the Kaplan-Meier method. Cox proportional hazard analysis was used to determine the independent effect of PLR. Thirty-six patients were reviewed. Elevated PLRs were more commonly noted in patients with an advanced vs an early stage of disease (88.9% vs 11.1%). Women with elevated PLR carried a higher rate of disease progression during primary therapy than that those in the normal PLR group (44.4 vs 22.2%). The median PFS for patients with elevated PLR was notably worse than that for patients with normal PLR (10 vs 34 months). Despite the impact of elevated PLR on PFS, it was found to be marginally significant when controlling for commonly applied prognostic markers. It, however, trended toward significance (HR=4.76; 95%CI, 0.95-23.8). In conclusion, an elevated PLR appears to be directly associated with adverse survival rather than being a surrogate for other indicators of a poor prognosis. PLR may be a useful biomarker for predicting survival of women with OCCC and merits further large-scale studies.

• Journal of Chest Surgery
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• 제53권1호
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• pp.1-7
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• 2020

Background: The aim of this study was to evaluate the short-term and long-term results of surgical treatment for native valve endocarditis (NVE) and to investigate the risk factors associated with mortality. Methods: Data including patients' characteristics, operative findings, postoperative results, and survival indices were retrospectively obtained from Hallym University Sacred Heart Hospital. Results: A total of 29 patients underwent surgery for NVE (affecting the mitral valve in 20 patients and the aortic valve in 9) between 2003 and 2017. During the follow-up period (median, 46.9 months; interquartile range, 19.1-107.0 months), the 5-year survival rate was 77.2%. In logistic regression analysis, body mass index (p=0.031; odds ratio [OR], 0.574; 95% confidence interval [CI], 0.346-0.951), end-stage renal disease (ESRD) (p=0.026; OR, 24.0; 95% CI, 1.459-394.8), and urgent surgery (p=0.010; OR, 34.5; 95% CI, 2.353-505.7) were significantly associated with in-hospital mortality. Based on Cox proportional hazard regression analysis, the statistically significant predictors of long-term outcomes were hypertension, ESRD, and urgent surgery. Conclusion: Surgical treatment for NVE is associated with considerable mortality. The in-hospital mortality and 5-year survival rates of this study were 13.8% and 77.2%, respectively. Underlying conditions, including hypertension and ESRD, and urgent surgery were independent risk factors for unfavorable outcomes.

• 대한수의학회지
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• 제39권4호
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• pp.838-845
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• 1999

To determine the prognostic factors for survival of dogs infected with canine parvovirus, clinical and laboratory data of 35 dogs with clinical signs compatible with canine parvoviral enteritis admitted to the Veterinary Medical Teaching Hospital, Seoul National University during the period 1997-1998 were collected. Dogs were grouped by some major covariates, which can be considered as guides to the relative prognosis of dogs in the different subgroups. The Kaplan-Meier survival analysis and Weibull proportional hazard model were used to estimate overall survival, evaluate the comparability between groups, and identify potential prognostic factors. The overall survival rate for all dogs was 45.7% over the study period, and the Kaplan-Meier estimate of one week survival was 0.4989. Gender was the most favorable prognosis ; male dog (median, 6 days) had significantly higher risk of dying than female dog (median, 17 days ; p = 0.0023). In addition to gender, age was significantly associated with survival, with juvenile dogs less than 6-month-old having higher risk (p = 0.0359). Dogs that vaccinated with complete protocol (p = 0.0374) and those of having higher value of mean corpuscular volume (p = 0.0346) were found to be of prognostic importance. The 7 dogs in which white blood cell count of less than 2000 had shorter median survival time (3 days) than the remaining 28 dogs (8 days), but no statistical significance was found between leukopenic and survival. The distribution of packed cell volume and hemoglobin measurement was such that the overall risk of dying in the two groups was comparable. Further studies are needed to more accurately assess these results.

• 한국식품위생안전성학회지
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• 제23권4호
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• pp.285-290
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• 2008

본 연구에서는 대표적인 즉석섭취식품 5종(김밥, 초밥, 회, 샐러드, 샌드위치)에 대한 미생물 모니터링 검사를 실시하여, 이들 제품에 대한 위생 안전성 확보를 위한 기초자료를 제공하기 위해 진행되었다. 이를 위해 전국의 대형 백화점, 할인점, 슈퍼 등지에서 판매되는 즉석섭취식품 5종, 총 440품목을 수거하여 위생지표세균 검사 및 식중독균 검사를 실시하였다. 제품별로는 초밥이 20.4%로 가장 높은 미생물 검출율을 보였으며, 그 다음으로 13.3%의 김밥, 12.5%의 회, 6.9%의 샐러드, 2.8%의 샌드위치의 순서로 나타났다. 검출된 미생물을 살펴보면 황색포도상구균이 6.6%로 가장 많이 검출되었으며, 다음은 2.7%의 대장균군, 2.3%의 리스테리아균, 0.7%의 바실러스 세레우스균, 0.5%의 대장균 순서로 검출되었으며, 장염비브리오균과 살모넬라균은 검출되지 않았다. 검출된 황색포도상구균의 정량분석 결과는 전체적으로 $200{\sim}5,500\;cfu/g$의 분포를 보였으며, 평균적으로는 600 cfu/g을 나타내었다.

• 한국유기농업학회지
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• 제25권2호
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• pp.431-443
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• 2017

본 연구는 안전한 육계 및 계란 생산에 기반이 되는 닭 농장의 HACCP 심사의 객관성을 높이기 위하여 현행 심사항목 점수부여 체계의 문제점에 대한 개선방안을 도출하기 위한 목적으로 실시하였다. 기존 닭 농장 HACCP심사항목은 중요도 수준의 구분 없이 동일한 점수(5점)를 부여하고 있으나 본 연구에서는 최근 3년간 지적비율, 위해의 심각도 수준 등을 고려하여 심사항목별로 중요도 수준을 도출하였고 그 결과에 따라 심사항목의 점수를 차등 부여하도록 하였다. 닭 농장의 선행요건 분야 심사항목(60개)은 중요도에 따라 최대 5점에서 최소 2점의 점수체계를 구축하여 총 점수가 200점이 되도록 하였으며, HACCP 관리 분야 심사항목(15개)은 최대 10점에서 최소 5점 체계를 구축하여 총 점수가 100점이 되도록 개발하였다. 본 연구결과를 현장에 적용할 경우 심사의 객관성을 높여 더욱 안전하고 위생적인 육계 및 계란 생산이 가능할 것으로 예상된다. 이는 나아가 닭 농장 HACCP 제도의 활성화와 소비자에게 보다 안전한 축산물을 공급할 수 있을 것으로 판단된다.

• 한국철도학회논문집
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• 제12권5호
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• pp.793-799
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• 2009

안전관리를 위해 정량화된 데이터를 바탕으로 통계기법을 통해 분석, 해석, 관리하는 기법은 제조업에서 수행하고 있는 6시그마 혁신운동과 거의 유사한 절차를 통해 수행되므로 철도안전관리에 있어서도 이러한 기법을 도입 하여 정량화된 관리기법이 도입되어야 한다. 본 연구에서는 경영혁신운동인 6시그마와 철도안전관리의 차이점에도 불구하고 제조업에서 성공적으로 활용하고 있는 6시그마 기법들을 철도안전에 적용할 수 있는 방안을 모색함으로써 일부 안전관리 과정에서 해결하지 못하거나 많은 어려움이 존재하고 있는 부분에 대한 해결책을 찾아 효율적이고 체계적인 철도안전관리에 일조하고자 한다.

• 산업경영시스템학회지
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• 제40권4호
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• pp.147-153
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• 2017

The mortality rate in industrial accidents in South Korea was 11 per 100,000 workers in 2015. It's five times higher than the OECD average. Economic losses due to industrial accidents continue to grow, reaching 19 trillion won much more than natural disaster losses equivalent to 1.1 trillion won. It requires fundamental changes according to industrial safety management. In this study, We classified the risk of accidents in industrial complex of Ulju-gun using spatial analytics and data mining. We collected 119 data on accident data, factory characteristics data, company information such as sales amount, capital stock, building information, weather information, official land price, etc. Through the pre-processing and data convergence process, the analysis dataset was constructed. Then we conducted geographically weighted regression with spatial factors affecting fire incidents and calculated the risk of fire accidents with analytical model for combining Boosting and CART (Classification and Regression Tree). We drew the main factors that affect the fire accident. The drawn main factors are deterioration of buildings, capital stock, employee number, officially assessed land price and height of building. Finally the predicted accident rates were divided into four class (risk category-alert, hazard, caution, and attention) with Jenks Natural Breaks Classification. It is divided by seeking to minimize each class's average deviation from the class mean, while maximizing each class's deviation from the means of the other groups. As the analysis results were also visualized on maps, the danger zone can be intuitively checked. It is judged to be available in different policy decisions for different types, such as those used by different types of risk ratings.

• 한국산업정보학회논문지
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• 제5권2호
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• pp.1-8
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• 2000

인력물자취급(MMH)작업은 작업현장에서 육체적 상해와 요통(LBP)을 발생시키는 주요 원인 중에 하나이며 이러한 산업재해는 점점 증가하고 있는 실정이다. 특히 좋지 않은 작업환경 즉, 비탈진 경사면에 위치한 농장이나 과수원, 항만부두의 하역작업, 경사진 벌목장 작업, 광산의 막장에서의 작업은 많은 재해의 위험성을 초래하며, 신체균형의 상실은 근골격계(musculoskeletal System)의 부상을 초래하게 된다. 본 연구는 경사면에서의 들기작업시 작업자의 근육의 force information과 근피로도를 측정하기 위해 EMG 시스템을 이용하였다. 측정결과 AEMG의 경우 모든 조건에서 일반적으로 multifidus 근육에 걸리는 부하가 다른 근육에서보다 많은 것으로 나타났고, 15$^{\circ}$, 20$^{\circ}$인 경우 neck extensors의 사용이 많은 것으로 나타났다. MPF천이 결과 공통적으로 multifidus부위 근육의 천이정도가 가장 많은 것으로 나타났다. 근육별 부하(%)에 대한 결과는 deep spinal 근육인 multifidus, erectorspinae부위가 상대적으로 많은 것으로 나타났고 neck extensor부위는 근육분담이 적은 것으로 나타났다.

• 대한방사선기술학회지:방사선기술과학
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• 제43권4호
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• pp.259-264
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• 2020

Radiation causes radiation hazards in the human body. In Korea, a case of radiation necrosis occurred in 2014. In this study, the scatter and shielding efficiency according to lead shielding were classified into epidermis and dermis for 0.511 MeV used in nuclear medicine. In this study, experiments were conducted using the slab phantom that represents calibration and the dose of human trunk. Experimental results showed that the shielding rate of 0.25 mmPb was 180% in the epidermis and 96% in the dermis. Shielding at 0.5mmPb showed shielding rates of 158%in the epidermis and 82% in the dermis. As a result of measuring the absorbed dose by subdividing the thickness of the dermis into 0.5 mm intervals, when the shielding was carried out at 0.25 mmPb, the dose appeared to be about 120% at 0.5 mm of the dermis surface, and the dose was decreased at the subsequent depth. Shielding at 0.5 mmPb, the dose appeared to be about 101% at the surface 0.5 mm, and the dose was measured to decrease at the subsequent depth. This result suggests that when lead aprons are actually used, the scattering rays would be sufficiently removed due to the spaces generated by the clothes and air, Therefore, the scattered ray generated from lead will not reach the human body. The ICRU defines the epidermis (0.07), in which the radiation-induced damage of the skin occurs, as the dose equivalent. If the radiation dose of the dermis is considered in addition, it will be helpful for the evaluation of the prognosis for radiation hazard of the skin.

• Safety and Health at Work
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• 제9권1호
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• pp.95-100
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• 2018

Background: Respiratory protection equipment (RPE) is the last resort to control exposure to workplace air pollutants. A comprehensive respiratory protection program (RPP) ensures that RPE is selected, used, and cared properly. Therefore, RPP must be well integrated into the occupational health and safety requirements. In this study, we evaluated the implementation of RPP in Iranian petrochemical industries to identify the required solutions to improve the current status of respiratory protection. Methods: This cross-sectional study was conducted among 24 petrochemical industries in Iran. The survey instrument was a checklist extracted from the Occupational Safety and Health Administration respiratory protection standard. An index, Respiratory Protection Program Index (RPPI), was developed and weighted by analytic hierarchy process to determine the compliance rate (CR) of provided respiratory protection measures with the RPP standard. Data analysis was performed using Excel 2010. Results: The most important element of RPP, according to experts, was respiratory hazard evaluation. The average value of RPPI in the petrochemical plants was $49{\pm}15%$. The highest and lowest of CR among RPP elements were RPE selection and medical evaluation, respectively. Conclusion: None of studied petrochemical industries implemented RPP completely. This can lead to employees' overexposure to hazardous workplace air contaminants. Increasing awareness of employees and employers through training is suggested by this study to improve such conditions.