• YAKHAK HOEJI
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• v.36 no.6
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• pp.518-528
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• 1992

To determine the optimal conformation of sulfonylureas, the correlation between conformation and hypoglycemic activity of the two sulfonylureas of tolbutamide and chlorpropamide as hypoglycemic agent was studied using an empirical potential function (ECEPP/2) and the hydration shell model in the unhydrated and hydrated states. The conformational energy was minimized from several starting conformations with possible torsion angles in each molecule. The conformational entropy change of each conformation was computed using a harmonic approximation. To understand the hydration effect on the conformation of the molecules in aqueous solution, the contribution of water-accessible volume of each group or atom in the lowest-free-energy conformation was calculated and compared each other. From comparison of the computed lowest-free-energy conformations of two sulfonylureas, it could be suggested that the hydration of sulfonylurea moiety is related to increase the hypoglycemic activity. From the calculation results, it was known that the conformational entropy is the major contribution to stabilize the low-free-energy conformations of two sulfonylureas in unhydrated state. Whereas, in hydrated state, the hydration free energy largely contributes to the total free energies of low-free-energy conformations of tolbutamide and conformational entropy contributes to stabilize the low-free-energy conformations of chlorpropamide. The torsion angles from phenyl ring to urea moiety of the low-free-energy conformations of the two sulfonylureas were shown the nearly regular trend. On the basis of these results, the conformation exhibiting the optimal hypoglycemic activity of sulfonylureas and the binding direction to pancreatic receptor site A could be predicted. Also, according to the side chain lengthening of urea moiety, tolbutamide showed various conformational change. Therefore, steric effect may be important factor in the interaction between sulfonylureas and the putative pancreatic receptor.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.30 no.4
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• pp.28-37
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• 2002

Acoustic behavior in combustion chamber with acoustoc cavity is numerically investigated by adopting linear acoustic analysis. Helmholtz-type resonator is employed as a cavity model to suppress acoustic instability passively. The tuning frequency of acoustic cavity is adjusted by varying the sound speed in acoustic cavity. Through harmonic analysis, acoustic pressure responses of chamber to acoustic oscillating excitation are shown and the resonant acoustic modes are identified. Acoustic damping effect of acoustic cavity is quantified by damping factor. As the tuning frequency approaches the target frequency of the resonant mode to be suppressed, mode split from the original resonant mode to lower and upper modes appears and thereby damping effect is degraded significantly. Considering mode split and damping effect as a function of tuning frequency, it is desirable to make acoustic cavity tuned to maximum frequency of those of the possible splitted upper modes.

• Water for future
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• v.15 no.3
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• pp.23-36
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• 1982

The stochastic variations and structures of time series data on water quality were examined by employing the techniques of autocorrelation function, variance spectrum, Fourier series, autoregressive model and ARIMA model. These time series included hourly and daily observation on DO, turbidity, conductivity pH and water temperature. The measurement was made by automatic recording instrument at Noryangjin and Dook-do located in the downstream part of Han River during 1975 and 1976. Hourly water quality time series varied with the dominant 24-hour periodicity, and the 12-hour periodicity was also observed. An important factor affecting 24-hour periodic variation of DO is believed to be photosynthesis by algae. These phenomena might be attributable to periodic discharges of municipal sewage. Noryangjin site showed the more distinct 12-hour periodicity than Dook-do site did, and tidal effect might be responsible for the difference. The water quality, as measured by DO and turbidity, was better in the afternoon compared with the quality in the morning. This change can be explained by the periodic variation of DO, temperature and the amount of municipal wewage discharge. It was also observed that the water temperature at Noryangjin was higher than the temperature at Dook-do. This difference might have been caused by the pollutants that were added to the section between two sites. The correlation coefficients between some of the variables were fairly high. For example, the coefficient was -0.88 between DO and water temperature, 0.75 between turbidity and river flow, and 0.957 between water temperature and air temperature. The lag time of heat transfer from the air to the water was estimated as 24 days. The first order auto-regressive model was appropriate for explaning standardized hourly DO time series. The ARIMA model of (1, 0, 0) type provided relatively satisfactory results for daily DO time series after the removal of significant harmonic value.

• Transactions of the Korean Society of Mechanical Engineers
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• v.16 no.12
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• pp.2328-2339
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• 1992

The propagation of coherent time-harmonic elastic L-and SV-waves is studied in a medium with random distribution of cylindrical inclusions. The purpose of the research is to characterize the dynamic elastic moduli and the attenuation properties of fiber-reinforced composite materials. The cylindes representing the fibers are assumed to be distributed in parallel with each other and the direction of incident waves are normal to the cylinder axes. A multiple scattering formula using the single scattering coefficients in conjunction with the Lax's quasicrystalline approximation is derived from which the dispersion relation for such medium is obtained. In order to formulate the multiple scattering interaction between cylinders, the pair correlation functions are generated by the Monte Carlo simulation technique. From the numerically evaluated complex wavenumbers, the propagation speed of the average wave, the coherent attenuation and the effective elastic moduli are presented as functions of frequency and fiber volume fraction.

• Bulletin of the Society of Naval Architects of Korea
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• v.22 no.3
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• pp.9-18
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• 1985

The numerical calculation for solving boundary-value problem related to potential flows with a free surface is carried out by application of the localized finite element method. Only forced motion of 2-D body in infinitely deep fluid is considered, although this schemes is equally applicable to any first order time-harmonic problems of similar nature. The infinite domain of the fluid is separated into the inner flow field and the outer flow field with common inter-surface boundary. The finite element method is applied to obtain the solution in the inner flow field and the Green functions are utilized to represent the solution in the outer flow field. At the inter-surface boundary, the continuity of the value of potential and the normal derivative of the potential(i.e. matching condition) is conserved. The present method has better computational efficiency than the previous LFEM and the integral equation method of Frank. This enhanced computational efficiency is presumably due to the fact that the present method gives a symmetric coefficient matrix and requires less computational time in calculating the influence coefficient matrix of Green function than the integral equation method. And the irregular frequency desen't exist because the uniqueness of the solution is assured by the such that the exact free surface condition is satisfied on the boundary of the localized finite element region(i.e. inner region). As an example of the above method, the hydrodynamic forces for the circular cylinder and the rectangular cylinders are calculated. In the computed results, the small number of singularity distribution segments($3{\sim}6$) give good result relative to Ursell's and Vugts'.

• Wind and Structures
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• v.20 no.2
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• pp.349-361
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• 2015

Higher-mode vertical vortex-induced vibrations (VIV) have been observed on several steel box-girder suspension bridges where different vertical modes are selectively excited in turn with wind velocity in accordance with the Strouhal law. Understanding the relationship of VIV amplitudes for different modes of vibration is very important for wind-resistant design of long-span box-girder suspension bridges. In this study, the basic rectangular cross-section with side ratio of B/D=6 is used to investigate the effect of different modes on VIV amplitudes by section model tests. The section model is flexibly mounted in wind tunnel with a variety of spring constants for simulating different modes of vibration and the non-dimensional vertical amplitudes are determined as a function of reduced velocity U/fD. Two 'lock-in' ranges are observed at the same onset reduced velocities of approximately 4.8 and 9.4 for all cases. The second 'lock-in' range, which is induced by the conventional vortex shedding, consistently gives larger responses than the first one and the Sc-normalized maximum non-dimensional responses are almost the same for different spring constants. The first 'lock-in' range where the vibration frequency is approximately two times the vortex shedding frequency is probably a result of super-harmonic resonance or the "frequency demultiplication". The main conclusion drawn from the section model study, central to the higher-mode VIV of suspension bridges, is that the VIV amplitude for different modes is the same provided that the Sc number for these modes is identical.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.13 no.5
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• pp.922-930
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• 2009

An optimized PWM switching strategy for an induction motor voltage control is developed and demonstrated. Space vector modulation in voltage source inverter offers improved DC-bus utilization and reduced commutation losses and has been therefor recognized the preferred PWM method especially in case of digital implementation. An optimized PWM switching strategy for an induction motor voltage control consists of switching between the two active and one zero voltage vector by using the proposed optimal PWM algorithm. The preferred switching sequence is defined as a function of the modulation index and period of a carrier wave. The sequence is selected by using the inverter switching losses and the current ripple as the criteria. For low and medium power application, the experimental results indicate that good dynamic response and reduced harmonic distortion can be achieved by increasing switching frequency.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.20 no.10
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• pp.3079-3094
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• 1996

Recently, the high-precision vibration attenuation technology becomes the essence fo the seccessful development of high-integrated and ultra-precision industries, and is expected to continue playing a key role in the enhancement of manufacturing technology. Vibration isolation system using an air-spring is widely employed owing to its excellent isolation characteristics in a wide frequency range. It has, however, some drawbacks such as low-stiffness and low-damping features and can be easily excited by exogenous disturbances, and then vibration of table is remained for a long time. Consequently, the need for active vibration control for an air-spring vibration isolation system becomes inevitable. Furthermore, for an air-spring isolation table to be successfully employed in a variety of manufacturing sites, it should have a guaranteed robust performance not only to exogenous disturbances but also to uncertainties due to various equipments which might be put on the table. In this study, an active vibration suppression control system using H.inf. theory is designed and experiments are performed to verify its robust performance. An air-spring vibration isolation table with voice-coil-motors as its actuators is designed and built. The table is modeled as 3 degree-of-freedom system. An active control system is designed based on $H_\infty$control theory using frequency-shaped weighting functions. Analysis on its performance and frequency responce properties are done through numerical simulations. Robust characteristics of$H_\infty$ control on disturbances and model uncertainties are experimentally verified through (i) the transient response to the impact excitation of the table, (ii) the steady-state response to the harmonic excitation, and (iii) the response to the mass change of the table itself. An LQG controller is also designed and its performance is compared with the $H_\infty$ controller.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.39 no.2
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• pp.143-156
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• 2015

The stress and displacement fields at the crack tip were studied during the unsteady propagation of a mode III crack in a direction that was different from the property graduation direction in functionally graded materials (FGMs). The property graduation in FGMs was assumed based on the linearly varying shear modulus under a constant density and the exponentially varying shear modulus and density. To obtain the solution of the harmonic function, the general partial differential equation of the dynamic equilibrium equation was transformed into a Laplace equation. Based on the Laplace equation, the stress and displacement fields, which depended on the time rates of change in the crack tip speed and stress intensity factor, were obtained through an asymptotic analysis. Using the stress and displacement fields, the effects of the angled property variation on the stresses, displacements, and stress intensity factors are discussed.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.41 no.5
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• pp.69-76
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• 2004

In this paper, a VCDRO (Voltage Control Dielectric Resonator Oscillator) with low phase noise for X-band application has been designed and fabricated. A low noise and low flicker noise MESFET and a high Q dielectric resonator were selected to obtain good phase noise Performance. Also, a varactor diode having high Q, qualify factor was used to reduce the loading effects and a big Gamma of diode was chosen for linearity of frequency over voltage tuning range. The fabricated circuits was simulated with circuit design tools, ADS to provide the optimum performances. As the measured results of fabricated oscillator, the output power was 5.8 ㏈m at center frequency 12.05㎓ and harmonic suppression -30㏈c, phase noise -114 ㏈c at 100 KHz offset frequency, respectively, and the frequency tuning range as the function of valtage applied to varactor diode was 15.2 MHz and its power variation with frequency was 0.2 ㏈. This oscillator could be available to a local oscillator in X-band.