• 대한예방한의학회지
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• 제9권1호
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• pp.119-133
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• 2005

Traditional herbal medicine is widely used among the Korean people, and other eastern Asian countries employ similar therapies as well. In recent years, due to increasing interest in herbal medicines, many researches have been made on the toxicity and side effects of herbal medications. Through private and public media, there have been many opinions suggesting taking herbal medicines is very harmful, especially on the liver and kidney functions. This assertion has been mainly presented by the doctors that practice western medicine, But this assertion is never based on adequate knowledge of herbal medicine. This study aims to provide the evidences that taking herbal medicines is safe on the renal functions. Four frequently used herbal medications(Sipjeondaebotang, Bojungigitang, Ojeoksan, and Yukmijihwangtang) were used to test the toxicity of herbal medicine oh the lab animal model(SD-Rat). There is no significant difference in body weight and kidney weight after herbal medication for 1 month. In all experimental groups, no abnormal findings were observed in histological study, and lab renal function index(BUN, creatinine, uric acid). These results say that four herbal multi-used-medicines, when medicated, is safe from the renal toxicity in lab animal model.

• 한국식생활문화학회지
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• 제16권1호
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• pp.1-12
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• 2001

The main purposes of this study are to know the contents and forms of impressions that the general public, and the consumerists and environmentalists have of irradiated food, and to know what information of irradiated food influences their impressions. Other purposes are to know what sources those impressions derive from, to know which media they have recently been exposed to and paid attention to irradiated food through, to know which sources they trust of information regarding irradiated food most greatly, and finally to suggest policies and strategies of communication in order to shed positive impressions of irradiated food on people. This study was conducted through the person-to-person interview survey toward 1,200 adults, and 150 consumerists and environmentalists in 1999. Adults are sampled nationally in South Korea. Only 8.7% of the general public have heard of irradiated food. Impressions of irradiated food that the general public mentioned most frequently are: harmful, insecure, negative, etc. The consumerists and environmentalists were found to have the most inaccurate knowledge of irradiated food. Television and newspaper were the major sources of impressions of, exposure to and focus of attention on irradiated food. Based on these results, we seem to devise methods to enhance impression of irradiated food by disseminating information of advantages and benefits that irradiation provides food with and to promote the fact that irradiation on food is totally irrelevant to being radioactive, danger of a nuclear power plant, genetically modifying food, etc.

• 한국물환경학회지
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• 제33권5호
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• pp.538-545
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• 2017

The purpose of this study is to investigate growth response and toxigenicity under various temperature and nutritional conditions, in order to understand the physioecological characteristics of Aphanizomenon flos-aquae, which is a bloom-forming cyanobacterium in the Nakdong River. The strain was inoculated into media under combinations of four temperatures (4, 12, 21, $30^{\circ}C$) and three nutrients (modified CB medium, P-depleted CB medium, N-depleted CB medium) for 28 days. The algae-inhibition tests were performed to assess the potential allelopathic effects of the strains' filtrates on the growth of four algae strains (Microcystis aeruginosa, Aulacoseria ambigua f. spiralis, Aphanizomenon flos-aquae, Scenedesmus obliquus). Toxin production of a strain was measured by Enzyme-Linked ImmunoSolbent Assay (ELISA). The optimal growth temperature (Topt) of strains was $19.9^{\circ}C$ ($18.3-21.2^{\circ}C$), and the temperature range for growth was from $-0.3^{\circ}C$ to $34.3^{\circ}C$. Specific growth rate (${\mu}$) in modified CB medium varied from 0.10 to $0.16day^{-1}$, and the maximum growth rate (${\mu}_{max}$) was $0.17day^{-1}$. Although growth curves under N-existed and N-depleted conditions were almost the same, growth under N-depleted condition was relatively slowed (${\mu}=0.09$ to $0.14day^{-1}$), with a decreased maximum cell density. However, growth under the P-depleted condition was restricted for all temperatures, Two stains of Aphanizomenon flos-aquae were confirmed as not producing toxins, because saxitoxin and cylindrospermopsin were not detected by ELISA. The exudates or filtrates from the Aphanizomenon flos-aquae (DGUC003) resulted in significant inhibition of algal growth on the Aulacoseira ambigua f. spiralis (DGUD001) and Aphanizomenon flos-aquae (DGUC001) (p < 0.01).

• 한국환경과학회지
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• 제29권11호
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• pp.1109-1123
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• 2020

In this study, the amount of harmful fungi and bacteria contained in the drainage and culture medium from the paprika hydroponic facility is identified. In addition, by proposing the necessity of effective purification of discharged drainage, this study attempted to confirm the possibility of drainage reuse. Finally, this study provides basic data on the basis for calculating the need for purification facilities in the future, as well as improvements in horticulture facility for sustainable agriculture. As a result of the analysis, a total of 12 types of fungi were detected in paprika medium and 10 types of fungi were detected in the drainage, and their densities were 130 and 68, respectively. Among the fungi detected in the media and drainage of the paprika hydroponic facility, the fungi with the highest detection frequency are Fusarium, Phytophthora, and Pythium. In the case of bacteria, a total of 2 types of bacteria were detected in the paprika facilities, and the density was 28 and 23, respectively. Therefore, in order to reuse the drainage and settle the circulating hydroponic cultivation system, a water treatment process capable of appropriate treatment is required.

• 한국양식학회지
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• 제12권1호
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• pp.7-14
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• 1999

갈래곰보의 원혈질체 분리와 배양 조건을 확립하여 생명공학기술에 의한 유전적 형질개량의 기초조건을 마련코자 하였다. Abalone acetone powder,소라의 내장조효소, Pseudomanas와 Vibrio의 조효소, Cellulas R-10, Macerozyme R-10, Hemicellulase, Pectinase, Driselase, Protease 등을 0.6M mannitol과 0.5% potassium dextran sulfate를 함유한 50mM MES 해수완충액(pH 6.0)에 단독 또는 조합하여 조제한 효소액을 갈래곰보의엽체에 처리하였을 때 Abalone acetone powder 4.0% + Macerozyme R-10 4.0% + Hemicellulase 4.0% 효소조합액의 처리로서 생체조직 1g당 $107.6{\times}10^4$개의 원혈질체를 분리시킬 수 있었다. 갓 분리한 원형질체는 투명한 타원형으로 $7{\mu} m$~ $24{\mu} m$의 범위에 분포하였다. 0.2M mannitol을 첨가한 $ASP_{12}$배지에 배양한 세포는 9일 후 분열되고 25일 후 발아하였다. $ASP_{12}$배지는 f/2배지보다 갈래 곰보의 원혈질체 배양에 효과적이었으며 Guillard 항생물질조합액의 처리는 분화에 장애가 되었다.

• 치위생과학회지
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• 제20권1호
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• pp.44-50
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• 2020

Background: Smartphones are a modern necessity. While they are convenient to use, smartphones also have side effects such as addiction. This study assessed the relationship between smartphone use, a part of everyday life in modern society, and oral health. Methods: An analysis was conducted using 2017 Korea Youth Risk Behavior Web-based Survey data. The propensity score estimation algorithm used logistic regression and 1:1 matching algorithm using nearest-neighbor matching. After matching, a total of 15,032 participants were classified into two groups containing 7,516 teenagers each who did and did not use smartphones, respectively. Results: Comparison of oral health behaviors according to smartphone use revealed a statistically significant difference in the frequency of tooth brushing per day, use of oral hygiene products, intake of foods harmful to oral health, and experience of oral health education (p<0.05). The factors affecting oral pain experience of adolescents were examined. Compared to male participants, female participants had an odds ratio of 1.627 for oral pain (p<0.05). According to the household income level, compared to the group with higher income, the group with lower income showed higher oral pain experience (p<0.05). Oral pain experience was 1.601 times more frequent among teenagers using smartphones (p<0.05). Conclusion: The results of this study indicated that use of smartphones by adolescents affected their oral health. These findings indicate the need for improved oral health management through the use of effective school oral health programs and individual counseling by oral health professionals, promotion of information dissemination through public media, and development of prevention strategies.

• 한국산학기술학회논문지
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• 제15권2호
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• pp.672-677
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• 2014

본 연구의 목적은 청소년 보호를 위한 광고 규제를 분석하여 문제점을 발견하고 개선 방안을 제시하는 것이다. 청소년 보호법을 근간으로 하여 청소년에게 유해한 매체물에 대해서는 광고를 포함한 모든 매체들이 규제를 받는다. 청소년 보호를 위한 주요 광고 관련 규제들 중에서 어린이 식생활안전관리 특별법, 방송법에 근거한 방송광고심의에 관한 규정 및 그 외 국민건강증진법의 청소년 보호 광고 규제 조항들을 분석하였다. 분석 결과, 청소년 보호를 위한 광고 규제들이 산만하게 흩어져 있어서 운용의 일관성 및 객관성이 우려되며, 현실과 동떨어진 규제 조항들이 발견되어 새롭게 정립할 필요성이 있고, 주류 광고 규제의 정립이 시급하다는 점이 발견되었다. 결론적으로 청소년 보호를 위한 통합된 단일의 광고 심의 규정 또는 가이드라인이 제정될 것을 제안하였다.

• The Plant Pathology Journal
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• 제33권4호
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• pp.362-369
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• 2017

White root rot disease, caused by the pathogen Rosellinia necatrix, is one of the world's most devastating plant fungal diseases and affects several commercially important species of fruit trees and crops. Recent global outbreaks of R. necatrix and advances in molecular techniques have both increased interest in this pathogen. However, the lack of information regarding the genomic structure and transcriptome of R. necatrix has been a barrier to the progress of functional genomic research and the control of this harmful pathogen. Here, we identified 10,616 novel full-length transcripts from the filamentous hyphal tissue of R. necatrix (KACC 40445 strain) using PacBio single-molecule sequencing technology. After annotation of the unigene sets, we selected 14 cell cycle-related genes, which are likely either positively or negatively involved in hyphal growth by cell cycle control. The expression of the selected genes was further compared between two strains that displayed different growth rates on nutritional media. Furthermore, we predicted pathogen-related effector genes and cell wall-degrading enzymes from the annotated gene sets. These results provide the most comprehensive transcriptomal resources for R. necatrix, and could facilitate functional genomics and further analyses of this important phytopathogen.

• 패션비즈니스
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• 제26권4호
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• pp.100-111
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• 2022

After the corona pandemic, when consumers choose clothes, the issue of sustainability has become a more important selection criterion. The eco-friendly functional fiber used in the study is a smartcell, which has functions such as UV protection, decomposition of harmful substances, deodorization, antibacterial and biodegradation. This eco-friendly functional fiber was dyed using five kinds of natural dyes to examine the color change according to dyeability and dyeing conditions. As natural dyes, gardenia, turmeric, sappan wood, lac, and indigo were used. For comparison with smartcell, rayon, a cellulose regenerated fiber, and wool fiber, a protein fiber, were dyed under the same conditions to compare dyeability and color. The study results are as follows. It was found that smartcell had superior dyeability compared to rayon and wool in gardenia dye and showed lower dyeability than wool when dyeing turmeric, sappan wood, and lac dyes, but showed superior or similar dyeability than rayon. In case of indigo dyeing, the dyeability of smartcell was the best when dyed once, but it was found that smartcell had a lower effect on repeated dyeing compared to wool or rayon. Therefore, smartcell has superior dyeability compared to rayon fiber in gardenia, turmeric, sappan wood, and lac dyeing, and in case of indigo dyeing, it is suitable for light dyeing. When smartcell is produced as textile fashion products, natural dyeing is actively introduced and commercialized, and it is hoped that this study can be a reference material.

• Journal of Audiology & Otology
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• 제23권2호
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• pp.63-68
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• 2019

Background and Objectives: To investigate the relationship between hearing impairment and alcohol drinking patterns in South Korean adults. Subjects and Methods: Data collection was performed by Korean National Health and Nutrition Survey from January 1 to December 31, 2012. Data analyses were performed from February 20 to March 3, 2018. Data from 3,860 adults 20 years of age or older without a history of malignancy or chronic otitis media in the Korean National Health and Nutrition Survey 2012 database who participated in the health questionnaires, and who had available results from otologic examinations that included pure tone audiogram, were included. Pure-tone average hearing thresholds were calculated at 500, 1,000, 2,000, and 4,000 Hz. Hearing loss was defined as a pure-tone average >40 dB in one or both ears. The Alcohol Use Disorder Identification Test was used to evaluate drinking statuses of subjects. Data were analyzed using the complex-sample χ²-test of independence and a complex-sample logistic regression analysis. Results: Of the 29,954,319 individuals in the weighted cross-sectional study population, 15,106,040 (50.4%) were men and 14,848,098 (49.6%) were women. A total of 8.1% of men and 7% of women had hearing impairment. The degrees of drinking with appropriate, risky, and hazardous drinking habits were 58.2, 32.1, and 9.7% among men; and 76.4, 12.5, and 11.1% among women, respectively. Among men, the odds ratio of hearing loss increased by 2.506 times when comparing hazardous and appropriate drinking (confidence interval, 1.083 to 5.800, p=0.002). Moderate alcohol consumption (≤2 drinks per day) was not protective for hearing in either group. Conclusions: As hazardous drinking tends to coexist with hearing impairment in men, appropriate prevention and intervention strategies should be emphasized. A longitudinal study to investigate harmful drinking and the mechanism of hearing loss should be performed.