• Title/Summary/Keyword: Hallucination

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Nefazodone and Associated Perceptual Disturbance : A Report of Four Cases (Nefazodons투여 후 지각이상을 보인 환자 4례)

  • Kim, Ji-Yun;Song, Hyoung-Seok;Cho, Bang-Hyun;Kim, Yong-Ku
    • Korean Journal of Biological Psychiatry
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    • v.6 no.2
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    • pp.259-263
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    • 1999
  • Nefazodone, a newer antidepressant is a phenylpiperazine derivative that inhibits the reuptake of both norepinephrine and serotonin, and antagonizes $5-HT_{2A}$ and ${\alpha}_1$ adrenergic receptors. Compared with SSRIs, nefazodone caused the fewer activating symptoms, adverse gastrointestinal effects(nausea, diarrhea, anorexia) and adverse effects of sexual function, but is associated with the more dizziness, dry mouth, constipation, visual disturbances and confusion. We report on 4 cases of visual disturbances and hallucinations in patients taking nefazodone. It is not certain what mechanisms mediated these side effects, but three mechanisms are possible. 1) Nefazodone, as a 5-HT2 antagonist, might induce visual disturbances. 2) mCPP, metabolite of nefazodone might contribute to the hallucination through action on 5-HT receptor. 3) Dopaminergic enhancing activity of nefazodone might cause hallucination. These case report raises the possibility that dose-related perceptual disturbances may exist with nefazodone. The fact emphasizes the need to pay close attention to all possible drug interactions, particularly in patients treated with multiple psychoactive agents, older patients, and patients with decreased hepatic function.

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Surrealistic Characteristics Expressed in Ignasi Monreal's Fashion Illustrations -Focusing on the 2018 S/S Gucci Hallucination Collection- (이그나시 몬레알(Ignasi Monreal)의 패션 일러스트레이션에 나타나는 초현실주의적 특성 -2018 S/S Gucci Hallucination 컬렉션을 중심으로-)

  • Son, Ju Hee;Chun, Jaehoon
    • Journal of the Korean Society of Clothing and Textiles
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    • v.46 no.3
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    • pp.407-423
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    • 2022
  • Fashion illustration is a language that expresses the inspirational imagination of designers. Like fashion, illustration reflects and records the social and cultural phenomena of the time. In this context, Ignasi Monreal's fashion illustration shows the characteristics that reveal modern people's ways of thinking and their desires. This study analyzed work by Ignasi Monreal in 'Gucci Hallucination' of 2018 S/S to examine the characteristics of his new painting style and the messages his fashion illustration aims to convey. He tried to harmonize his surrealistic digital illustrations of Greek mythology with Gucci items. As a result of this study, the characteristics of Monreal's illustration works were divided into two main categories: formal aspects (similarity of composition or subject and use of dépaysement techniques), and content aspects (expression of a mythical surreal being). These qualities differentiate Monreal's fashion illustration from that of other artists. In addition, his works on the myth of Icarus not only express the desires of modern people but also convey social satirical messages.

The Empirical Analysis of Factors Affecting the Intention of College Students to Use Generative AI Services (대학생의 생성형 AI 서비스 이용의도에 영향을 미치는 요인에 대한 실증분석)

  • Chang, Soo-jin;Chung, Byoung-gyu
    • Journal of Venture Innovation
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    • v.6 no.4
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    • pp.153-170
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    • 2023
  • Generative AI services, including ChatGPT, were becoming increasingly active. This study aimed to empirically analyze the factors that promoted and hindered the diffusion of such services from a consumer perspective. Accordingly, a research model was developed based on the Value-based Adoption Model (VAM) framework, addressing both benefit and sacrifice factors. Benefits identified included usefulness and enjoyment, while sacrifices were security and hallucination. The study analyzed how these factors affected the intention to use generative AI services. A survey was conducted among college students for empirical analysis, and 200 valid responses were analyzed. The analysis utilized structural equation modeling with AMOS 24. The empirical results showed that usefulness and enjoyment had a significant positive impact on perceived value, while security and hallucination had a significant negative impact. The order of influence on perceived value was usefulness, hallucination, security, and then enjoyment. Perceived value had a significant positive impact on usage intention. Moreover, perceived value was found to mediate the relationship between usefulness, enjoyment, security, hallucination, and the intention to use generative AI services. These findings expanded the research horizon academically by validating the effectiveness of generative AI services based on existing models and demonstrated the continued importance of usefulness in a practical context.

Exploring Factors to Minimize Hallucination Phenomena in Generative AI - Focusing on Consumer Emotion and Experience Analysis - (생성형AI의 환각현상 최소화를 위한 요인 탐색 연구 - 소비자의 감성·경험 분석을 중심으로-)

  • Jinho Ahn;Wookwhan Jung
    • Journal of Service Research and Studies
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    • v.14 no.1
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    • pp.77-90
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    • 2024
  • This research aims to investigate methods of leveraging generative artificial intelligence in service sectors where consumer sentiment and experience are paramount, focusing on minimizing hallucination phenomena during usage and developing strategic services tailored to consumer sentiment and experiences. To this end, the study examined both mechanical approaches and user-generated prompts, experimenting with factors such as business item definition, provision of persona characteristics, examples and context-specific imperative verbs, and the specification of output formats and tone concepts. The research explores how generative AI can contribute to enhancing the accuracy of personalized content and user satisfaction. Moreover, these approaches play a crucial role in addressing issues related to hallucination phenomena that may arise when applying generative AI in real services, contributing to consumer service innovation through generative AI. The findings demonstrate the significant role generative AI can play in richly interpreting consumer sentiment and experiences, broadening the potential for application across various industry sectors and suggesting new directions for consumer sentiment and experience strategies beyond technological advancements. However, as this research is based on the relatively novel field of generative AI technology, there are many areas where it falls short. Future studies need to explore the generalizability of research factors and the conditional effects in more diverse industrial settings. Additionally, with the rapid advancement of AI technology, continuous research into new forms of hallucination symptoms and the development of new strategies to address them will be necessary.

A Case of Combination Therapy of Psychosocial Treatment and Oriental Medical Treatment On Schizophrenia (정신사회적 치료와 한방요법을 병행한 정신분열병 환자의 증례고찰)

  • Choi, Bo-Yun;Jung, In-Chul;Lee, Sang-Ryong;Ha, Su-Young
    • Journal of Oriental Neuropsychiatry
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    • v.15 no.1
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    • pp.247-254
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    • 2004
  • Schizophrenia is a frequent psychotic disorder. Recently many studies raised biochemical theory as a cause of schizophrenia. But in this case, we used psychosocial treatment and oriental medical treatment, without antipsychotic drugs for 4 months, obtained good results. Practicing psychosocial treatment, we were able to remove anxiety and fear of the patient. In addition positive symptoms, for example auditory hallucination and delusion, were improved. Schizophrenia conforms to JEONKWANG(癲狂) in oriental medicine. We concluded this case to JEONJUNG(癲證) due to QIULDAMHWA(氣鬱痰火). So we used herbal medication and acupuncture according to oriental medical theory and these efforts helped the care of disease.

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Removing object hallucination through a reviewing mechanism (객체 탐지 및 빔 서치를 이용한 영상 주석 환각 해결)

  • Ko, Jieun;Jung, Seungjun;Kim, Changick
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2019.06a
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    • pp.243-245
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    • 2019
  • 영상 주석 생성 기술은 주어진 영상에 대하여 최대한 자세히 묘사하는 문장을 생성하는 것을 목표로 한다. 따라서, 이 분야에서는 생성된 주석과 입력 영상 간의 연관성이 가장 중요하다. 영상 주석 생성과 관련된 최근 연구들은 영상 내에서 집중해야 될 후보 영역들을 먼저 추출한 뒤, 이들을 LSTM 디코더 등에 입력하여 주석을 생성한다. 비록, 최근에 제안된 방법들이 입력 영상과 매우 연관성 높은 주석들을 생성하지만, 아직 영상 안에 존재하지 않는 물체가 종종 생성된 주석에 포함되는 환각(Hallucination) 문제가 발생하고 있다. 본 논문에서는 이를 해결하기 위하여 Beam search를 이용하여 기존 방법들보다 더 정확한 여러 주석 후보 군을 생성한 뒤, 각각의 주석을 객체 검출기에서 나온 객체 후보군과 비교하는 방법을 제안한다. 우리는 제안한 방법을 최근에 제안된 주석 생성 기술에 접목한 결과, 환각 문제가 효과적으로 제거되는 것을 확인할 수 있었다. 또한, MS COCO 온라인 서버 제출을 통하여 주석 생성기술의 성능이 향상되는 것을 확인하였다.

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Association of Therapeutic Response and Change of Mismatch Negativity in Schizophrenia Patients (조현병 환자의 치료 반응에 따른 Mismatch Negativity 변화)

  • Lee, Soyoen;Rhie, Eui Hyeok;Kim, Jong Woo;Kang, Won Sub
    • Korean Journal of Biological Psychiatry
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    • v.24 no.4
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    • pp.188-195
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    • 2017
  • Objectives Schizophrenia is characterized by disturbances in perception and cognition. Attenuated mismatch negativity (MMN) reflects central auditory dysfunction in schizophrenia. The aim of this study is to compare MMN changes before and after treatment in schizophrenia patients and to assess their association with treatment response. Methods Twenty-three schizophrenia patients underwent an oddball paradigm. MMN was calculated by the difference waveforms of the event-related potentials (ERPs) elicited by subtracting standard from deviant stimulus. The clinical symptoms were measured by the Positive and Negative Syndrome Scale (PANSS), the Psychotic Symptom Rating Scale (PSYRATS). Follow-up evaluation was conducted when the PANSS total score decreased by 30% or more (treatment response group) or before discharge (non-response group). Results The treatment response group showed significantly larger MMN amplitude improvement and latency reduction than the non-response group after treatment (Fz ; mean amplitude p = 0.035, FCz ; p = 0.041). The auditory hallucination group showed shorter latency than that of the group without hallucinations. Additionally, auditory hallucination was associated with prolonged MMN latency and shortened after treatment in the auditory hallucination response group (Fz ; p = 0.048). Conclusions These results suggest that the attenuated MMN amplitude reflects the progression of the disease. The increment of MMN amplitude and shortening of latency after treatment may reflect cognitive functional recovery of central auditory sensory processing.

Patterns of Delusions and Hallucinations in Schizophrenia : Comparison between the 1990s and the 2000s (조현병 입원 환자의 망상과 환각 : 1990년대와 2000년대의 비교)

  • Jung, Hyun-Jin;Kim, Daeho;Oh, Hyun Young;Park, Yong-Chon
    • Korean Journal of Biological Psychiatry
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    • v.20 no.3
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    • pp.80-85
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    • 2013
  • Objectives Research suggests that content of delusion and hallucination in schizophrenia is influenced by culture and social environment. However, few studies investigated chronological change of delusions and hallucinations within a society. To investigate changes in delusions and hallucinations of schizophrenia according to time, we compared contents of symptoms between inpatients with schizophrenia at two different time frames. Methods All admissions to a psychiatric unit of Hanyang University Guri Hospital with discharge diagnoses of schizophrenia at two different five-year time frames (1996-2000 and 2006-2010) were reviewed. Using a checklist, adapted from the Scale for Assessment of Positive Symptoms, we investigated delusions and hallucinations of 247 patients (104 in the 1990s and 143 in the 2000s). Results Delusions and hallucinations of patients did not differ at two time frames. In women, however, auditory and somato-tactile hallucinations were significantly more frequent in the 1990s (p < 0.05). Conclusions Our findings support the literature emphasizing that content and frequency of hallucination may differ according to cultural environment. We speculate that attitude toward sex and defensiveness toward disclosure of symptoms may have contributed to interval difference.

A Case Report of a Schizophreniform Disorder Treated by Oriental Medical Treatment and Emotional Freedom Techniques. (양약 복용 후 추체외로증후군을 나타낸 정신분열형 장애 환자에게 EFT 요법과 한방치료를 병행하여 치료한 치험 1례)

  • Lee, Ji-Won;Cha, Hye-Jin;Seo, Young-Min;Seo, Deok-Won;Park, Se-Jin
    • Journal of Oriental Neuropsychiatry
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    • v.20 no.2
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    • pp.207-216
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    • 2009
  • Objectives : Schizophreniform Disorder can be put as pre-stage of Schizophrenia, which is known as one of the most common mental disorder. Many studies have shown that Antipsychotic Treatment for Schizophrenia has many side effects such as EPS(Extrapyramidal Symptoms), and recently it has been found that even Non-Antipsychotic Treatment has side effects such as weight gain. This clinical study was aimed to search the therapeutic effects of Oriental medicine in Schizophreniform Disorder, and in reducing the side effects of Western medicine. Methods : We treated the patient diagnosed as Schizophreniform Disorder, whose chief complaint was auditory hallucination, with herbal medicine and acupuncture. Improvement in her clinical symptoms were recorded daily. We also used Emotional Freedom Techniques to control her anxiety effectively. Results : Auditory hallucination and extrapyramidal symptoms such as tremor disappeared. The patient's anxiety was controlled by Emotional Freedom Techniques effectively. Conclusions : From the above results, we conclude that Oriental medical treatment is effective in treating clinical symptoms of Schizophreniform Disorder, as well as in reducing the side effects of Western medicine.

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Psychosis in Parkinson's Disease-Treatment with 5-HT Receptor Antagonist (5-HT 수용체 길항제를 이용한 파킨슨 환자의 정신 증상의 치료)

  • Koh, Seong-Beom;Park, Kun-Woo;Lee, Dae-Hie
    • Korean Journal of Biological Psychiatry
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    • v.4 no.1
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    • pp.132-135
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    • 1997
  • Current treatment strategies for levodopa-induced psychosis in advanced Parkinson's disease have had limited success. Reduction or discontinuation of levodopa and coadministration with dopamine-blocking neuroleptics may attenuate the psychotic symptoms, but these strategies are associated with worsening of parkinsonian symptoms. Administration of 5-HT3 receptor antagonist ; ondansetron, a newer strategy to attenuate psychosis of Parkinson'disease without motor deterioration was introduced. A 41-year-old young-onset male, who was diagnosed as Parkinson's disease 7 years ago, was treated with levodopa therapy, and had levodopa-induced psychosis(delusion, hallucination, paranoid, insomnia). After trial of ondansetron, he showed improvement in the Brief Psychiatric Rating Scale(from 21 points to 9 points) in spite of increasing the dosage of levodopa. With ondansetron, we could increase the dosage of levodopa without psychotic complications(esp, hallucination), and he showed improvement in the motor fluctuation.

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