• Title/Summary/Keyword: Half Life Time

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Measurement of Effective Half-life Using Dual Time I-131 Whole Body Scan in Patients with Differentiated Thyroid Cancer Treated by High Dose Therapy (고용량 방사성옥소 치료를 받은 갑상선분화암 환자에서 Dual Time I-131 Whole Body Scan을 이용한 유효반감기의 측정)

  • Yoon, Jae Sik;Lee, Jae Gon;Lee, Ki Hyun;Lim, Kwang Seok;Choi, Hak Ki;Lee, Sang Mi
    • The Korean Journal of Nuclear Medicine Technology
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    • v.18 no.1
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    • pp.98-103
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    • 2014
  • Purpose: The effective half life of I-131 is useful to calculate radiation dose, period of hospitalization, and exposure dose of surrounding people from patient. However, it is difficult to measure. This study estimates the effective half life in whole body and thyroid in using of value of residual radioactivity obtained from the early and delay images of Dual time I-131 whole body scan. Also, the correlations between the effective half life and serum creatinine, GFR, and administration dose were investigated in this study. Materials and Methods: The targets were 50 patients administration high dose of I-131 from February to August in 2013, having normal range of serum creatinine and over $30{\mu}IU/mL$ of TSH levels. After administration radioactive I-131, the early scan in the 3rd day and the delay scan in the 5-6th days were performed. To measure the residual radioactivity in the whole body and thyroid, ROI was set and then background radioactivity was corrected to estimate. The effective half life was estimated by calculating the ratio of measured values between the early and delay images. To compare the effective half lives of the whole body and thyroid, it was analyzed by Independent t-test, and each correlation of the effective half life, GFR, serum creatinine, and the dose of administration were analyzed by calculating the pearson's correlation coefficient. All of the analysis were determined to be statistically significant when P<0.05. Results: The effective half life of the whole body was $17.06{\pm}5.50$ hours and of the thyroid was $17.22{\pm}5.41$ hours. The two effective half life did not show significant difference (P=0.887). As the value of GFR was increased, the effective half life of whole body (r=-0.407, P=0.003) and of thyroid (r=-0.473, P=0.001) were significantly decreased; as the value of serum creatinine was increased, the effective half life of whole body (r=0.309, P=0.029) and of thyroid (r=0.371, P=0.008) were significantly increased. In the administration dose, effective half life did not have correlations. Conclusion: The effective half life of I-131 of patients treated for their thyroids were estimated only by using the images of Dual time I-131 whole body scan. Also, the correlations with the effective life, GFR, and serum creatinine were examined. This study might be utilized for a study on optimization for the period of hospitalization of patients treated by high dose of I-131 and on evaluation for internal absorbed dose of MIRD schema in application of the effective half life.

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The Optimization of Ozone Solubility and Half Life Time in Ultra Pure Water and Alkaline Solution on Semiconductor Wet Cleaning Process (반도체 습식 세정 공정 중 상온의 초순수와 염기성 수용액 내에서 오존의 용해도 최적화)

  • Lee Sang-Ho;Lee Seung-Ho;Kim Kyu-Chae;Kwon Tae-Young;Park Jin-Goo;Bae So-Ik;Lee Gun-Ho;Kim In-Jung
    • Journal of the Semiconductor & Display Technology
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    • v.4 no.4 s.13
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    • pp.19-26
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    • 2005
  • The process optimization of ozone concentration and half life time was investigated in ultra pure water and alkaline solutions for the wet cleaning of silicon wafer surface at room temperature. In the ultra pure water,. the maximum concentration (35 ppm) of ozone was measured at oxygen flow rate of 3 liters/min and ozone generator power over 60%. The half life time of ozone increased at lower power of ozone generator. Additive gases such as $N_2$ and $CO_2$ were added to increase the concentration and half life time of ozone. Although the maximum ozone concentration was higher with the addition of $N_2$ gas, a longer half life time was observed with the addition of $CO_2$. When $NH_4OH$ of 0.05 or 0.10 vol% was added in DI water, the pH of the solution was around 10. The addition of ozone resulted in the half life time less than 1 min. In order to maintain high pH and ozone concentration, ozone was continuously supplied in 0.05 vol% ammonia solutions. 3 ppm of ozone was dissolved in ammonia solutions. The static contact angle of silicon wafer surface became hydrophilic. The particle removal was possible alkaline ozone solutions. The organic contamination can be removed by ozonated ultra pure water and then alkaline solution containing ozone can remove the particles on silicon surface at room temperature.

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Determination of Residual Concentration and Half-life Time in Soils of Imidazole Fungicide Prochloraz (Imidazole계 살균제 Prochloraz의 토양 중 잔류량과 반감기분석)

  • Choi, Yong Hwa;Han, Seong Soo;Kim, Il Kwang
    • Analytical Science and Technology
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    • v.15 no.1
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    • pp.67-71
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    • 2002
  • The residual analysis and half-life time of imidazole fungicide prochloraz in soils (silty clay) were investigated by gas chromatography equipped electron capture detector (GC-ECD). The soil samples were extracted acetone/hexane(1:1) solvent and analyzed after separated by $LC-NH_2$ Sep-Pak solid column. Linear sensitivity of standard calibration curve was Y = 268.8600X + 0.0664, $R^2=0.9998$ between 0.05~1.00 ng. The detection limit was 0.02 mg/L and the average recoveries were 94.5~97.3% from the standard additional experiments with 0.10 and 0.40 mg/L. The half-life time was 24.4 days in room laboratory and 7.6 days in the field test soil.

Dissipation and Processing Factor of Etofenprox and Fenitrothion Residue in Chinese Matrimony Vine by drying (건조에 따른 구기자 중 etofenprox와 fenitrothion의 잔류량 변화 및 가공계수)

  • Noh, Hyun Ho;Lee, Jae Yun;Park, Hyo Kyoung;Jeong, Hye Rim;Lee, Jung Woo;Jo, Seung Hyeon;Kwon, Hyeyoung;Kyung, Kee Sung
    • Korean Journal of Environmental Agriculture
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    • v.37 no.3
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    • pp.213-220
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    • 2018
  • BACKGROUND: This study was carried out to determine characteristics of residual pesticides in time-dependent manner and calculate half-lives of the residual pesticides in fresh and dried Chinese matrimony vine. In addition, processing factors were calculated based on the residual concentrations in them. METHODS AND RESULTS: The test pesticides, etofenprox and fenitrothion, were sprayed onto the Chinese matrimony vine plants at once or twice (at seven-day interval) and then samples were collected at 0 (after 3 hours), 1, 3, 5 and 7 days after the last spraying. Dried samples were prepared in hot-air drying oven at $60^{\circ}C$ for 48 hours until water content of less than 20%. Residual concentrations of etofenprox in fresh and dried samples decreased by 54.0-60.9% after 7 days of the last pesticide-application. In case of fenitrothion, the concentrations were found to have decreased by 69.2-76.5%. Processing factors of etofenprox were 2.6-3.0 for the one-time spraying and 2.5-3.0 for the two-time spraying and those of fenitrothion were found to be 1.5-22 for the one-time spraying and 1.6-2.0 for the two-time spraying. First half-lives of etofenprox and fenitrothion in fresh and dried samples ranged from 5.0 to 6.3 and from 3.4 to 4.0 days, respectively. The third half-lives were found to be 15.0-18.9 and 10.2-12.1 days, respectively. CONCLUSION: Residual concentrations of the tested pesticides in the studied crop decreased, but those in the dried samples appeared to have increased. In addition, processing factor and half life were constant regardless of spraying times.

Analysis of Half-life Time and Residual Concentration of Ethalfluralin Herbicide in Soils (토양 중 제초제 Ethalfluralin의 잔류 농도와 반감기 분석)

  • Han, Seong Soo;Rim, Yo Sup;Kim, Il Kwang
    • Analytical Science and Technology
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    • v.10 no.3
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    • pp.168-178
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    • 1997
  • The optimum conditions for the residual analysis of the ethalfluralin herbicide on soils were investigated and the residues in soils were determined by gas chromatography with electron capture detector(GC-ECD). The soil samples extracted with methanol and dichloromethane and concentrated. The concentrated phase were redissolved with toluene and analyzed with GC-ECD after separated by cyanosilica gel Sep-Pak cartridge. From the standard addition experiments with 0.1 and 1.0ppm, the average recoveries were 92.8~101.2% and the detection limit was 0.004ppm. The half-life time of ethalfluralin in the soil(A) was 35 days in the laboratory and 7.2 days in the field test whereas it was 45 days and 9.7 days for each in case of soil(B).

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Process Optimization for Life Extension of Electropolishing Solution using Half Round Bus Bar (반구형 부스바를 이용한 전해연마액 수명연장을 위한 공정 최적화)

  • Kim, Soo Han;Lee, Seung Heon;Cho, Jaehoon;Lim, Dong-Ha;Choi, Joongso;Park, Chulhwan
    • Journal of the Korean institute of surface engineering
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    • v.49 no.5
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    • pp.447-453
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    • 2016
  • In this study, we intended to extend the life of electropolishing solution through the reduction of electric resistance by improving the electrolysis efficiency. The optimum conditions were obtained by half round bus bar and Taguchi method. As the main control factors in the electropolishing process, current density, polishing time, electrolyte temperature and flow rate were selected. The electrolyte temperature was the most significant to the electrolysis efficiency. The optimum conditions for the life extension of electropolishing solution were as follows: current density, $45A/dm^2$; polishing time, 6 min; electrolyte temperature, $70^{\circ}C$; flow rate, 11 L/min. As a results of ANOVA of SN ratios, it was found that the electrolyte temperature was significant factor at the 90% confidence level.

A Study on the Error Associated with Ventilation Rate Calculation Using Different Sampling Intervals (측정시간에 따른 거주주택의 환기량 계산 오류에 관한 연구)

  • 양원호;배현주;이기영;정문호
    • Journal of Environmental Health Sciences
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    • v.26 no.3
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    • pp.50-54
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    • 2000
  • Ventilation rates can be measured directly by a tracer decay method, although little is known of the effects of different sampling intervals on decay rte calculations. This study determined variations in decay rates calculated by three techniques using residential ozone decay data. The calculation techniques were a regression technique, decay techniques using half-life and average-life, and finite difference techniques using two different time intervals. Variation associated with regression technique calculations for residential ozone decay rates based on data from both sample intervals were within 10% (2.81$\pm$1.88 hr-1). However, both half-life and finite difference technique calculations using a shorter-time interval were significantly different from those obtained with the regression technique(p<0.05). Therefore, the use of short sampling intervals in tracer decay may cause significant error in decay rate calculations.

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The Comparative Study of Software Optimal Release Time of Finite NHPP Model Considering Half-Logistic and Log-logistic Distribution Property (반-로지스틱과 로그로지스틱 NHPP 분포 특성을 이용한 소프트웨어 최적방출시기 비교 연구)

  • Kim, Hee Cheul
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.9 no.2
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    • pp.1-10
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    • 2013
  • In this paper, make a study decision problem called an optimal release policies after testing a software system in development phase and transfer it to the user. In the course of correcting or modifying the software, finite failure non-homogeneous Poisson process model, presented and was proposed release policies of the life distribution, half-logistic and log-logistic distributions model which used to an area of reliability because of various shape and scale parameter. In this paper, discuss optimal software release policies which minimize a total average software cost of development and maintenance under the constraint of satisfying a software reliability requirement. In a numerical example, the parameter estimation using maximum likelihood estimation of failure time data make out, and software optimal release time was estimated.

A Study on the Effect of Aftertreating(Antistatic and Softening) Agents in Laundering (시판 세탁후처리제(대전방지 및 유연처리제)의 효과에 관한 연구)

  • Lee Yang Hun
    • Journal of the Korean Society of Clothing and Textiles
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    • v.9 no.2
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    • pp.27-34
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    • 1985
  • Cotton, P/C and polyester fabrics were laundered and treated with 4 kinds of aftertreating agent(antistatic and softening agents) on marketing. Some treating condition:. which include agent concenteration, treating time and rinsing extent after laundering, were varied. And then the effects of agents with each treating condition-handle value, charged voltage and half-life, and crease recovery etc.-were determined and discussed about their change. The improvement of handle and antistatic properties by treatment were indicated remarkably for cotton fabric and P/C and polyester fabrics respectively. Generally, the handle value of cotton was decreased and then increased again, and the charged voltage and half-life of P/C and polyester fabrics were decreased with increase of concenteration of agents. The effect of antistatic improvement for P/C fabric was larger than polyester fabric at even lower concenteration of agents. The effects were increased with treating time and rinsing extent. In particular, those of short time(1 minute) treatment were very small.

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Analysis of Blood Flow-dependent Blood Nitric Oxide Level and Half-life of Nitric Oxide in Vivo

  • Kim Cuk-Seong;Kim Hyo-Shin;Lee Young-Jun;Park Jin Bory;Ryoo Sung-Woo;Chang Seok-Jang;Jeon Byeong-Hwa
    • International Journal of Vascular Biomedical Engineering
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    • v.1 no.2
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    • pp.13-19
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    • 2003
  • Endothelial release of nitric oxide (NO) contributes to the regulation of vascular tone by inducing vascular relaxation. To estimate the blood flow-dependent nitric oxide level and half-life (T1/2) of nitric oxide in vivo state, we investigated the change of aortic NO currents during the change of aortic blood flow rate using NO-selective electrode system and electromagnetic flowmeter in the aorta of anesthetized rats. Resting mean aortic blood flow rate was $49.6{\pm}5.6ml/min$ in the anesthetized rats. NO currents in the aorta were increased by the elevation of blood pressure and/or blood flow rate. When the aortic blood flow was occluded by the clamping, aortic NO currents were decreased. The difference of NO concentration between resting state and occluded state was $1.34{\pm}0.26{\mu}M$ (n=7). This NO concentration was estimated as blood flow-dependent nitric oxide concentration in the rats. Also, while the aortic blood flow was occluded, NO currents were decreased with exponential pattern with $12.84{\pm}2.15$ seconds of time constant and $7.70{\pm}1.07$ seconds of half-life. To summarize, this study suggested that blood flow-dependent NO concentration and half-life of nitric oxide were about $1.3{\mu}M$ and 7.7 seconds, respectively, in the aorta of anesthetized rats. The nitric oxide-selective electrode system is useful for the direct and continuous measurement of NO in vivo state.

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