• Title/Summary/Keyword: Half Life

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쌀 입자 크기에 따른 콩죽의 이화학적 및 영양학적 특성 (Effect of Particle Size of Rice on Physicochemical and Nutritional Properties of Soybean Porridge)

  • 유보람;김미리
    • 동아시아식생활학회지
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    • 제20권1호
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    • pp.187-192
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    • 2010
  • The study investigated the effect of rice particle size on the physicochemical properties of soybean porridge prepared at different pH. Redness, yellowness and viscosity of soybean porridge increased according to the rice particle size. Protein content of soybean porridge was increased 2-fold, compared to that of rice porridges. Total amino acid content of soybean porridge was 1,821.2 mg/100 g and that of rice was 1,719.1 mg/100 g. Lysine and threonine contents of limited amino acid of soybean porridge were increased. Half grain rice soybean porridge exhibited the highest sensory scores. The results indicated that half grain size soybean porridge is preferred, both physicochemically and nutritionally.

게임 제작 프로세스의 발전적 측면에서 본 모드게임 예시 연구 - 소비자 참여를 중심으로- (A Case Study of the Mod: a Developmental Perspective in Game Development Process - Focusing on Customer Involvement -)

  • 유보미;유승호
    • 한국게임학회 논문지
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    • 제9권1호
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    • pp.55-62
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    • 2009
  • 게임은 이용하는 사람이 선택할 수 있는 자율성의 폭이 넓은 열린 문화(open culture)이다. 즉, 게임 소비자의 참여가 적극적으로 요구되고 수용된다. 그런 의미에서, 원작 게임에 여러 가지 변형을 가하는 모드(MOD)는 게임 이용자의 적극적인 참여를 나타내는 대표적인 사례이자 게임 제작 과정에서 소비자의 참여 가능성을 보여주는 예시이다. 본 연구는 모드 게임의 대표적인 사례 중 Half-Life 모드의 분석을 통해, 게임 제작 과정의 발전적 측면에서 본 소비자 참여 가능성에 대해 논의한다.

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Thermal annealing for long-term stability of polymer light-emitting devices

  • Kim, Jin-Ook;Park, Jong-Hyn;Lee, Jae-Yoon;Lee, N.Y.;Chung, In-Jae
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2003년도 International Meeting on Information Display
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    • pp.153-156
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    • 2003
  • Thermal annealing of a polymer light-emitting diode (PLED) is shown to result in a remarkable improvement in the long-term stability of the device. The best half-life is obtained at an annealing temperature above the $T_g$ of emitting polymer. It is shown that the annealing of the emitting polymer layer results in a more than an order of magnitude increase in the half-life in spite of a decrease in the efficiency of the device as the annealing temperature increases.$^1$

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입체구조적으로 안정화된 리포좀의 특성 및 혈장내 안정성 (Characterization of Sterically Stabilized Liposomes and Their Stability in Rat Plasma in Vitro)

  • 이지혜
    • 약학회지
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    • 제44권3호
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    • pp.251-256
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    • 2000
  • Sterically stabilized liposomes (SSL) composed of distearoylphosphatidylcholine, cholesterol, dicetylphosphate and distearoylphosphatiodylethanolamine-N-poly(ethyleneglycol) 2000 (DSPE-PEG 2000) were made by reverse phase evaporation method to prolong biological half-life and decrease toxic side effect of drug. Streptozocin (572), a water-soluble antitumor agent with short half-life, was selected as a model drug. The size of SSL was controlled by polycarbonate extrusion to 100 nm which is adequate size for long circulation in plasma. The release rate of drugs from SSL in PBS was evaluated. And the stability of STZ-containing liposomes against drug leakage into rat plasma was evaluated in order to investigate the interaction of liposome and plasma protein. Incorporation of DSPE-PEG 2000 into conventional liposomes significantly decreased the drug leakage into rat plasma.

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시판 세탁후처리제(대전방지 및 유연처리제)의 효과에 관한 연구 (A Study on the Effect of Aftertreating(Antistatic and Softening) Agents in Laundering)

  • 이양헌
    • 한국의류학회지
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    • 제9권2호
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    • pp.27-34
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    • 1985
  • Cotton, P/C and polyester fabrics were laundered and treated with 4 kinds of aftertreating agent(antistatic and softening agents) on marketing. Some treating condition:. which include agent concenteration, treating time and rinsing extent after laundering, were varied. And then the effects of agents with each treating condition-handle value, charged voltage and half-life, and crease recovery etc.-were determined and discussed about their change. The improvement of handle and antistatic properties by treatment were indicated remarkably for cotton fabric and P/C and polyester fabrics respectively. Generally, the handle value of cotton was decreased and then increased again, and the charged voltage and half-life of P/C and polyester fabrics were decreased with increase of concenteration of agents. The effect of antistatic improvement for P/C fabric was larger than polyester fabric at even lower concenteration of agents. The effects were increased with treating time and rinsing extent. In particular, those of short time(1 minute) treatment were very small.

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실험적(實驗的) 신장장애(腎臟障害) 가토(家兎)에서 탄산리튬의 약물동태학적(藥物動態學的) 연구(硏究) (Pharmacokinetics of Lithium Carbonate in Rabbits with Experimental Renal Failure)

  • 범진필;김용현
    • Journal of Pharmaceutical Investigation
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    • 제15권3호
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    • pp.113-120
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    • 1985
  • The pharmacokinetics of lithium carbonate were investigated in rabbits with folate-induced renal failure. The blood level, the area under the blood concentration curve (AUC) and the biological half·life were increased significantly, and the urinary excretion was decreased significantly compared with those of normal rabbits. Correlation of serum creatinine concentration and AUC, biological half-life, and correlation of creatinine clearance and renal clearance of lithium carbonate have linear relationship respectively. In short, dosage regimen of lithium carbonate is considered to be adjusted in the dose size and the dosing interval by degree of experimental renal failure.

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노르플록사신의 체내동태에 대한 신장해의 영향 (Effect of Renal Failure on Pharmacokinetics of Norfloxacin in Rabbits)

  • 이종기
    • Journal of Pharmaceutical Investigation
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    • 제25권3호
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    • pp.265-270
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    • 1995
  • The pharmacokinetics of norfloxacin (100 mg/kg, oral) in renal failure rabbits was studied. Renal failure rabbits were induced by the i.v. injection of folate (50,100 and 150 mg/kg). These produced significant increases of serum creatinine concentration $(S_{cr})$ and blood urea nitrogen (BUN). Plasma concentration and AUC of norfloxacin significantly increased. Elimination rate constant $(K_{el})$ of norfloxacin significantly decreased, and half-life $(t_{1/2})$ of norfloxacin significantly increased. Correlation between serum creatinine concentration $(S_{cr})$ and half-life $(t_{1/2})$ of norfloxacin, and correlation between BUN and AUC of norfloxacin have linear relationship respectively. These results suggest that adjustment or the dosage regimen of norfloxacin is desirable, and serum creatinine concentration $(S_{cr})$ as well as BUN can be used an index for adjusting the dosage regimen of norfloxacin in renal failure.

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간장병태(肝臟病態) 가토(家兎)에서 아세트아미노펜의 약물동태학적(藥物動態學的) 연구(硏究) (Pharmacokinetics of Acetaminophen in Rabbits with Carbon Tetrachloride Induced Hepatic Failure)

  • 이진환;최준식;범진필
    • Journal of Pharmaceutical Investigation
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    • 제14권4호
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    • pp.156-160
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    • 1984
  • The pharmacokinetics of acetaminophen administered intravenously(20mg/kg) was investigated in the rabbits of carbon tetrachloride induced hepatic failure. The blood level, the total AUC and the biological half life of acetaminophen were increased significantly in hepatic failure rabbits compared with those of normal rabbits. The urinary excretion and the overall elimination rate of acetaminophen were decreased significantly in hepatic failure rabbits. There was significant relationship between GOT value and AUC or biological half life of acetaminophen.

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탄소나노튜브를 이용한 폴리우레탄 코팅소재의 대전방지성 (Properties of Anti-static Material Using Carbon Nanotube)

  • 김종원;송선혜;윤석한;송병갑;추교진;안훈주
    • 한국염색가공학회지
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    • 제19권4호
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    • pp.26-31
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    • 2007
  • Nanocomposite resin(PUD-CNT) composed of Carbon nanotube(CNT) and Polyurethane Dispersion (PUD) was prepared by different contents of CNT($0{\sim}5%$). PUD-CNT was coated on samples, and their electrical conductivity was investigated. With increasing CNT content, static change, half life and surface resistance decreased. Composites having 5% CNT showed $10^9{\Omega}/cm$(surface resistance), and 40V (stactic charge). Respectively, From this results, PUD-CNT can be used as a antistatic material.

에토석시미드의 HPLC 분석법 및 한국인에서의 약동학적 특징 (HPLC Determination and Pharmacokinetic Profile of Ethosuximide in Korean Subjects)

  • 배정우;김지홍;양상인;김현경;장춘곤;한혜원;박영서;손의동;이석용
    • 약학회지
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    • 제47권6호
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    • pp.444-459
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    • 2003
  • Ethosuximide is an oral anticonvulsantic agent used in the first choice anti-absence seizure drug. The purpose of this study was to assess the pharmacokinetic profile of the ethosuximide in healthy Korean volunteers and to develop the efficient assay method of ethosuximide in human plasma. The pharmacokinetics of ethosuximide administered orally was evaluated after a dose of 500 mg. Ethosuximide was assayed from plasma by a specific HPLC method reading absorbance at 195 nm. AUC was 1222$\pm$160 $\mu\textrm{g}$/$m\ell$$.$hr, $C_{max}$ 14.2l$\pm$1.74 $\mu\textrm{g}$/$m\ell$, $T_{max}$ 1.06$\pm$0.62 hr and half-life 77.83$\pm$12.46 hr. The half-life in Korean was longer than, in Caucasian (53∼56 hr).).).