• Title/Summary/Keyword: Half Life

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Detoxification Properties of Guanidinylated Polyethyleneimine Treated Polypropylene Non-woven Fabric Against Chemical Warfare Agents (구아니딘화 폴리에틸렌이민이 처리된 폴리프로필렌 부직포의 군사용 화학 작용제 제독 특성)

  • Kim, Jiyun;Kwon, Woong;Kim, Changkyu;Jeong, Euigyung
    • Textile Coloration and Finishing
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    • v.33 no.1
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    • pp.1-9
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    • 2021
  • This study aims to prepare the fabric with detoxification properties against chemical warfare agent by the simple treatment. For this purpose, polypropylene non-woven fabric(PP) was treated with polyethyleneimine(PEI) and guanidinylated PEI and detoxification properties of the guanidinylated PEI treated PP were evaluated using diisopropylfluorophosphate(DFP), as a chemical warfare agent simulant, and compared with the untreated and PEI treated PP. The half-lives of DFP on guanidinylated PEI treated PP and untreated PP were 334 min and 714 min, respectively. The half-life of DFP with guanidinylated PEI treated PP was 53.22% shorter than with untreated PP. This result shows that guanidine group in guanidinylated PEI treated PP was acted as a base catalyst for hydrolysis of DFP and decreased half-life of DFP. Therefore, it is expected that guanidinylated PEI treatment can be an simple pathway to prepare the detoxification fabric material for protective clothing against chemical warfare agents.

A Study on the Effective Half-life after the High Dose Radioactive Iodine (131I) Therapy for Thyroid Cancer Patients (갑상선암 환자에서 고용량 방사성요오드 치료 후 유효반감기에 대한 연구)

  • Kim, Seongcheol;Gwon, DaYeong;Kim, Yongmin
    • Journal of the Korean Society of Radiology
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    • v.11 no.7
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    • pp.597-603
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    • 2017
  • High-dose $^{131}I$ therapy has been generally carried out to remove remaining thyroid tissue or to cure metastasize lesion of patients who received full thyroidectomy due to differentiated thyroid cancers. In case high-dose $^{131}I$ therapy is carried out for a patient, the patient should be hospitalized being isolated for a certain period in order to restrict the amount of exposure to radiation of people at large from the patient within the limit of a level of radiation. Effective half-life is an important value to calculate how family members are exposed to radiation from a patient or to decide the period of isolation of the patient from the family members. Therefore, in this study we calculated the effective decay constant, effective half-life and period of isolation of high-dose $^{131}I$ therapy patient using NM670 SPECT/CT. As a result of carrying out this study, the effective half-life of high-dose $^{131}I$ therapy patients was derived and the time to reach the discharge level of 1.2 GBq was confirmed. When they were compared with each other in each of curative doses, the effective half-life did not have significant difference, but the time when the level of radiation remaining in the interior of the body to reach the criteria of isolation and discharge showed significant difference and it could be confirmed that the higher the curative dose the longer the period of isolation becomes. When the effective half-lives in each type of preparation were compared with each other, they did not show significant difference. However, When the times to reach the level of radiation that is the criteria of isolation and discharge in each type of preparations, they showed significant difference. The cause of the shortening of the isolation period for rhTSH patients group is decided to be low curative dose. Accordingly, if the current national health insurance (the insurance is applied to using of rhTSH in 3.7 GBq or lower) is maintained, while discerning them in each of types of preparation, we would be able to discharge patients at the time earlier than the current period of isolation (2 nights and 3 days).

A Study on Influential Factors Related to the Level of life Satisfaction of the Elderly Residents at Paid Facilities (유료시설 거주노인의 생활만족도 영향요인)

  • 서병숙
    • Journal of Families and Better Life
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    • v.14 no.4
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    • pp.129-144
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    • 1996
  • The purpose of this study was to illuminate the ways to im-prove the level of life satisfaction of the elderly who chose or happened to live at paid facilities by examining some of factors such as individual family social support and facility related el-ements that would influence their life satisfaction. The interview outcomes came out in three main discussions. First the general characteristics of the participating elderly appeared to be that most of them were ver7y elderly relatively highly educated females and religions and the rate of being ill was high. And a half of them considered themselves as heal- thy people and the other half as unhealthy. Secondly in view of statisticsal results the level of their life satisfaction was influnced by their individual family and facillity related factors. As far as their individual related factor are concerned the level of one party's life satisfaction was relative-ely higher than that of other's when the person is female had religio presumed oneself as in healthy and good physical condition. And when participating member keeps good relation-ship with his or her own children the level of the person's life satisfaction was only slightly higher than other elderly group who did not have good relationship with their children. There were no other significant statistical differences on the level of their life satisfaction related to the social support factors between those two group. Thirdly the level of the elderly's life satisfaction was influe- nced in the order of folldwing factors: (1) the quality of facility living condition 2) the commitment of ownership of the organization (3) the elderly residents' own education level (4) the elderly's own subjectivel health condition and (5) the sex of the individuals.

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Foreign and Domestic Influence of the First Half of the Twentieth-Century American Furniture

  • Kim, Seong-Ah
    • Journal of the Korea Furniture Society
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    • v.18 no.4
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    • pp.324-336
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    • 2007
  • Throughout the twentieth century, American furniture was subject to a number of influences-both domestic and foreign. Especially, in the first half of the twentieth century, there were strong foreign influences compare to the later half of the century. Therefore, this study aimed for discussing foreign influences and for addressing issues such as attitudes toward materials, ornamentation, and technology. As a result, this study suggests how American furniture becomes instinctive moving away from strong foreign influences from the second half of the century. The twentieth century was a period of rapid and dynamic change for American furniture design. In many ways, the designs throughout the century were reflective of the social, political, and economic culture of the time. With the birth of the modern movement in Europe and a strong influx of foreign immigrants, American design in the first half of the century was characterized by a reliance on European and foreign influences. However, after the two world wars, strong domestic influences came into play. The two world wars provided the essential catalysts for change: new materials, developing technology, and changes in life style and consumer values. A historical examination of design trends and individual designers illustrates how American furniture design evolved during this period.

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Operation and Training Demand on Dietary Life Education of Nutrition Teachers in Jeonbuk Province (전북지역 영양교사의 식생활교육 실태와 연수 요구도 분석)

  • Park, Eunsook
    • Korean Journal of Human Ecology
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    • v.23 no.1
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    • pp.149-161
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    • 2014
  • The purpose of this study was to investigate the nutrition teachers' operation and demand of dietary life education in Jeonbuk Province. The study was carried out using a self administered questionnaire and the subjects were 190 nutrition teachers. The questions were general characteristics of the subjects, operating status as frequency, place, the main use time, and training demand on dietary life education by elementary school and middle & high school, teaching career, and training hours. The results are as follows. Most of the subjects were female(98.9%), more than half were 40's(52.1%) in their age, school work career was 13.2 years. Frequency of the dietary life education operation was once per month(56.8%), 2~3 times per month(27.9%), and place of education were dinning room (49.7%), classroom(25.9%). Almost of the subjects(90.4%) recognized the facilities for education was lack, 89.3% of them did the education materials was lack, also. The desirable frequency of dietary life education was once per month(48.9%), and once per week(35.3%.) The half of the subjects recognized the objects of the dietary life education was not only students but also their parents and teachers. The proper education time was dietary life education tim (34.2%), discretion activity time(31.1%). Most of the subjects(95.7%) had willing to get training, the proper training program was 30 hours, and they prefer summer vacation(61.0%) than winter vacation(30.5%) and semester(8.6%). Proper experimental practice ratio of environment : health : thanks were 30% : 43% : 27%. It is concluded that the demand of nutrition teachers is necessary for their education program in elementary and middle & high school.

Prediction of Continuous Reactors Performance Based on Batch Reactor Deactivation Kinetics Data of Immobilized Lipase

  • Murty, V.Ramachandra;Bhat, Jayadev;Muniswaran, P.K.A.
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.7 no.4
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    • pp.225-230
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    • 2002
  • Experiments on deactivation kinetics of immobilized lipase enzyme from Candida cyl-indracea were performed in stirred bath reactor using rice bran oil as the substrate and temperature as the deactivation parameter. The data were fitted In first order deactivation model. The effect of temperature on deactivation rate was represented by Arrhenius equation. Theoretical equations were developed based on pseudo-steady state approximation and Michaelis -Menten rate expression to predict the time course of conversion due to enzyme deactivation and apparent half-life of the immobilized enzyme activity in PFR and CSTH under constant feed rate polity for no diffusion limitation and diffusion limitation of first order. Stability of enzyme in these continuous reactors was predicted and factors affecting the stability were analyzed.

Pharmacokinetic Study of Decursinol Following Oral Administration in Rat (데커시놀추출물의 경구투여후 흰쥐에 있어서의 약물속도론적 연구)

  • Kim, Ji-Hae;Choi, Song-Am;Kim, Dong-Chool
    • Journal of Pharmaceutical Investigation
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    • v.33 no.3
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    • pp.195-199
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    • 2003
  • The objective of this study is to investigate the pharamacokinetic parameters of decursinol following oral administration in Sprague-Dawley rats. The plasma concentration of decursinol was determined by LC/MS with APCI positive mode. The m/z value of decursinol was observed at 247. Following oral administration of decursinol extract, the apparent clearance was $5.3{\pm}2.7\;ml/hr/rat$, the absorption half life was $2.5{\pm}0.41\;hr$, the elimination half life was $3.05{\pm}1.57\;hr$, and the apparent volume of distribution was $21{\pm}12\;ml/rat$. The LC/MS method was successfully applied to the pharmacokinetic study of decursinol.

Inter-Region Relative Price Convergence in Korea

  • Moon, Seongman
    • East Asian Economic Review
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    • v.21 no.2
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    • pp.123-146
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    • 2017
  • This paper examines the persistence of relative consumer price indices for 15 regions in Korea including 6 metropolitan cities and 9 provinces over the period of 1990-2016. In particular, we ask if relative regional price indices contain a common stochastic trend and find that they are not. We then investigate how quickly these relative prices converge to their long run value and find that a half-life of a deviation from the long run value is in the range of 13 to 22 months for the aggregate consumer price indices and in the range of 7 to 13 months for the tradable goods price indices, which is much quicker than the estimates of previous studies. These estimates suggest that existing monetary models with the realistic duration of price rigidities can generate the persistence in relative price indices.

A Study about Ozonized Water Making that Use $O_3$ (오존화 기체를 이용한 오존수 제조에 관한 연구)

  • Park, Hyun-Mi;Lee, Chang-Ho;Lee, Sang-Geun;Song, Hyun-Jig;Yoon, Byeng-Han;Lim, Chang-Ho;Lee, Kwang-Sik
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2004.11a
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    • pp.339-342
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    • 2004
  • It is research about special quality of ozone gas concentration and dissolved ozone concentration that show according to change of flow rate when liquefied ozone gas in water. If increase flow rate of ozone gas, ozone concentration increases being proportional and amount to fixed flow rate, dissolved ozone concentration was measured low. When ozone concentration How rate 1000 [ppm], dissolved ozone concentration smelted to flow rate 1.5[Q] for 28 [min] is $0.1740{\sim}0.8020[mg/l]$. Could know that half-life is most short by 3 minutes 8 seconds in flow rate 1.5 [Q]. And ozone smelted 20 minutes later after half-life measurement became disjointing all.

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Limitation of Protein Half-life Prediction in Computational Approach Based on N-end Rule (N-end rule 기반 단백질 수명 예측 프로그램의 한계)

  • Ryu, Jea Woon;Kim, Hak Yong
    • Proceedings of the Korea Contents Association Conference
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    • 2011.05a
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    • pp.339-340
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    • 2011
  • 본 연구는 N말단 아미노산 종류에 따라 단백질의 수명(half-life)이 결정된다는 N-end rule을 기반으로 단백질 수명을 예측해주는 프로그램인 protparam의 결과와 bleach-chase를 이용한 실험 데이터를 비교 분석하였다. 단백질 수명을 결정하는 여러 요인들을 고려하지 않고 한 가지 요인만을 반영한 protparam의 결과는 실제 측정값과 현격한 차이를 나타낸다. 특히 실제 단백질은 NME(N-terminal Methionine Excision) 현상이 일어나는데 이를 고려하지 않고 유전체에서 번역한 그대로의 아미노산 서열을 가지고 단백질 수명을 계산하는 한계를 가지고 있다. 이에 본 연구에서 N말단 아미노산을 순차적으로 제거하여 N-end rule을 적용한 결과도 실험 데이터와 일치하지 않는 결과를 보여주고 있음을 확인하였다. 따라서 현재 사용되고 있는 단백질 수명 예측 프로그램은 이런 문제점을 가지고 있기 때문에 새로운 예측 알고리즘의 개발이 요구된다.

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