• Title/Summary/Keyword: Half Life

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A Study on the Error Associated with Ventilation Rate Calculation Using Different Sampling Intervals (측정시간에 따른 거주주택의 환기량 계산 오류에 관한 연구)

  • 양원호;배현주;이기영;정문호
    • Journal of Environmental Health Sciences
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    • v.26 no.3
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    • pp.50-54
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    • 2000
  • Ventilation rates can be measured directly by a tracer decay method, although little is known of the effects of different sampling intervals on decay rte calculations. This study determined variations in decay rates calculated by three techniques using residential ozone decay data. The calculation techniques were a regression technique, decay techniques using half-life and average-life, and finite difference techniques using two different time intervals. Variation associated with regression technique calculations for residential ozone decay rates based on data from both sample intervals were within 10% (2.81$\pm$1.88 hr-1). However, both half-life and finite difference technique calculations using a shorter-time interval were significantly different from those obtained with the regression technique(p<0.05). Therefore, the use of short sampling intervals in tracer decay may cause significant error in decay rate calculations.

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Dissipation Pattern of Amisulbrom in Cucumber under Greenhouse Condition for Establishing Pre-harvest Residue Limit (생산단계 잔류허용 기준 설정을 위한 시설 재배 오이 중 살균제 Amisulbrom의 잔류특성 연구)

  • Hwang, Kyu-Won;Kim, Tae Wan;Yoo, Jae-Hong;Park, Byeoung-Soo;Moon, Joon-Kwan
    • The Korean Journal of Pesticide Science
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    • v.16 no.4
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    • pp.288-293
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    • 2012
  • The dissipation patterns of amisulbrom in cucumber under a greenhouse condition was investigated to establish biological half-life and pre-harvest residue limit (PHRL). Amisulbrom residue in/on cucumber on the day of application under standard application condition was $0.15mg\;kg^{-1}$ and decreased to $0.06mg\;kg^{-1}$ after 5 days after treatment, so that biological half-life calculated 3.6 day, while initial concentration of amisulbrom twice application 3 days interval under standard application condition was $0.35mg\;kg^{-1}$ and decreased to $0.09mg\;kg^{-1}$ after same period and the biological half-life calculated 2.4 day. PHRL was suggested by prediction curve calculated from the decay constant of amisulbrom at standard rate. For example, $1.83mg\;kg^{-1}$ at 5 days before harvest and $1.03mg\;kg^{-1}$ at 2 days before harvest were suggested.

Recent Research Trend on Free Radical Scavenger and Metallothioneins on Cadmium (Cadmium에 대한 Metallothionein 및 Free Radical Scavenger에 관한 최근의 연구 동향)

  • 김영숙;유대식
    • Journal of the East Asian Society of Dietary Life
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    • v.11 no.1
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    • pp.1-10
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    • 2001
  • Since the Industrial Revolution, people have enjoyed an abundant life, owing to the technological innovations of science. However, because of changes in the environment or polution to the environment, it has brought on many chronic diseases. Especially, even though it may be a small amount, if cadmium gets into a human body, because its biological half life is long, it fatally causes a kidney disease and damage to human organisms. It was reported that Metallothioneins(MT), a substance that is closely related with a free radical that comes from environmental pollution and the course of which cadmium, which causes chronic addition in the body, is formed, along with harmful metals, make the toxicity reduce. MT compound led into the body by cadmium indirectly functions as an antioxidation, supplied adequate amount of vitamin E, and suppresses the accumulation of cadmium in heart, liver and blood. Cadmium content found in Korean soil according to the test conducted from 1992 to 1996 was 0.02~0.03mg/kg in cereals, pulses, and potatoes. Free radical scavenger, finding solution for metal substance that comes from environmental pollution from food and natural substances implicates a better future for the study of food science.

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Purification and Characterization of a Bacteriocin, BacBS2, Produced by Bacillus velezensis BS2 Isolated from Meongge Jeotgal

  • Perumal, Venkatesh;Yao, Zhuang;Kim, Jeong A;Kim, Hyun-Jin;Kim, Jeong Hwan
    • Journal of Microbiology and Biotechnology
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    • v.29 no.7
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    • pp.1033-1042
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    • 2019
  • Bacillus velezensis BS2 was isolated from meongge (common sea squirt) jeotgal, a Korean fermented seafood, and produces a bacteriocin, BacBS2, which strongly inhibits Listeria monocytogenes and Bacillus cereus. BacBS2 was partially purified by Q-Sepharose column chromatography after ammonium sulfate precipitation of the culture supernatant, then further purified by Sephadex G-50 column chromatography. Partially purified BacBS2 was estimated to be 6.5 kDa in size by Tricine-SDS PAGE and activity detection by gel-overlay. Enzyme treatment and FT-IR spectrum of partially purified BacBS2 confirmed its proteinaceous nature. BacBS2 was fully stable at pH 4-9, and half of activity was retained at pH 1-3. Full activity was retained after exposure to $80^{\circ}C$ for 15 min, but half of the activity was retained upon exposure to $90^{\circ}C$ for 15 min or $100^{\circ}C$for 10 min. BacBS2 inhibited L. monocytogenes by bactericidal mode of action. B. velezensis BS2 and its BacBS2 seem useful as biopreservatives for fermented foods such as jeotgal.

Failure Analysis in Al 7075-T651 Alloy using X-ray Diffraction Technique (X-선 회절을 이용한 A1 7075-T651합금의 파손해소)

  • 오세욱;박수영;부명환
    • Journal of Ocean Engineering and Technology
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    • v.7 no.2
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    • pp.103-113
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    • 1993
  • X-ray diffraction analysis technique was used for the fatigue damage analysis and fatigue life prediction in Al 7075-T651 alloy. The tensile test, fatigue strength and fatigue crack propagation test with change of stress ratio were carried out. As a result, half-value breadth was increased with the plastic deformation in the specimen increasint at all test conditions. In particular, half-value breadth at the surface of the specimens fractured by fatigue was increased as stress intensity factor range and effective stress intensity factor range were increased. In addition, the good relationship between half-value breadty and diffraction pattern was shown.

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Elucidation of Environment Factors Affecting the Differences in the Half-Life of the Insecticide Cyfluthrin in Soil between Field and Laboratory Tests (포장과 실내실험에서 살충제 Cyfluthrin의 토양 중 반감기 차이에 미치는 환경요인 구명)

  • Lim, Bang-Hyun;Lim, Yo-Sup;Choi, Yong-Hwa;Han, Seong-Soo
    • Applied Biological Chemistry
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    • v.43 no.4
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    • pp.291-297
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    • 2000
  • This study was conducted to find out the environmental factors affecting the differences in the half-life of the insecticide cyfluthrin in soil between field and laboratory tests carried out in 1998. Degradation and leaching of cyfluthrin in soil were examined under various environmental conditions that were considered to affect the residuality. Cyfluthrin was degraded 1.9 times faster in non-sterilized soil than in sterilized soil and 1.2 times at $25^{\circ}C$ than at $15^{\circ}C$. The half-lives of cyfluthrin were 61.4 days under the dark condition and 4.5 days under sunlight, and those were 11.8 days under the open condition and 23.8 days under the closed condition. The half-lives of the authentic compound and the commercial product of cyfluthrin were 15 and 1 day in the field test and 26 and 3 days in the laboratory test, respectively. Cyfluthrin was rapidly degraded with an increase in soil moisture content and decomposed faster in the alkaline solution of pH 12 than in the acidic solution of pH 3, but the half-life of cyfluthrin did not make any difference between pH 6.4 of the field test soil and pH 5.6 of the laboratory test soil. Cyfluthrin was immobile in soil from the results that $81{\sim}94%$ of the initial amount remained in the $0{\sim}2\;cm$ layer of the soil column regardless of the amount and time of rainfall after the chemical treatments. From viewing the abovementioned results, soil moisture content, sunlight and formulation type affected greatly soil microbes and volatilization affected slightly, and temperature, pH and rainfall did not affect the big difference in the half-life of cyfluthrin in soil between the field and laboratory tests in the year of 1998.

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In vitro Mass Propagation of Ardisia pusilla DC. (산호수 (Ardisia pusilla DC.)의 기내 대량번식)

  • Kang Gwan-Ho;Oh Owel-Sun;Goo Dae-Hoe;Eun Jong-Seon;Kim Hyung-Moo
    • Journal of Plant Biotechnology
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    • v.32 no.4
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    • pp.281-285
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    • 2005
  • To establish the mass proliferation system of Ardisia pusilla DC, the shoot tips of Ardisia pusilla DC were cultured on the MS and half-strength MS medium supplemented with $0{\sim}5.0$ mg/L BA or $0{\sim}0.5$ mg/L thidiazuron(TDZ), respectively. A few multiple shoot formation observed when the shoots were cultured on MS medium containing TDZ. However, the frequency of multiple shoot formation was reached up to 82.4%, when the shoots were cultured on half-strength MS medium supplemented with 0.5 mg/L BA. Also the number of shoot per explant was 7.1. To promote rooting from multiple shoot, newly formed shoots were transferred to half-strength MS medium containing 0.5 mg/L IBA or 0.5 mg/L NAA, respectively. Regenerated plantlets were grown to normal mature plants in soil.

Field tolerance of pesticides in the strawberry and comparison of biological half-lives estimated from kinetic models (Kinetic models에 의한 딸기 중 농약의 생물학적 반감기 비교와 생산단계잔류허용기준 설정)

  • Park, Dong-Sik;Seong, Ki-Young;Choi, Kyu-Il;Hur, Jang-Hyun
    • The Korean Journal of Pesticide Science
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    • v.9 no.3
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    • pp.231-236
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    • 2005
  • This study was conducted to determine the amounts of pesticide residues after treatment of criterion dose with 4 pesticides(tolclofos-m, folpet, procymidone, and triflumizole) under cultivated period and to compare the biological half-life of pesticides with 6 kinetic models(first, zero and second order kinetics, power function, elovich and parabolic model) and to establish proposed field tolerance using biological half-lives. Recovery of 4 pesticides form strawberry was ranged from 85.1 to 105.5%. For all of 4 pesticides, dissipation rate was over 73% at 5 days after application. Among 6 kinetic models, first order kinetic model (FO) was best fit to describe the relationship between residual pattern of pesticides and time. Therefore, half-lives were calculated by FO for establishing the field tolerance. These results showed that half-life should be calculated by comparative best fit kinetic model and field tolerance can help to prevent unacceptable agricultural products from marketing. It is good for both consumers and farmers having safe agricultural products and financial benefits, respectively.

Half lives of Gaseous Organochlorine Pesticides in Atmosphere (대기 중에서 가스상 유기염소계 살충제의 반감기)

  • Choi, Min-Kyu;Chun, Man-Young
    • Environmental Analysis Health and Toxicology
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    • v.22 no.2 s.57
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    • pp.177-184
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    • 2007
  • Gaseous organochlorine pesticides (OCPs : heptachlor epoxide, p, p'-DDE, ${\gamma}-HCH,\;{\alpha}-chlordane,\;{\gamma}-chlordane$ and trans-nonachlor) concentration was measured using PUF high volume sampler from June, 2000 to June, 2002 in the semi-rural atmosphere. The OCPs concentration in atmosphere, which is estimated by the slope (m) of Clausius-Clapeyron equation and phase-transition energy $({\Delta}H)$, was influenced by revolatilization from environmental matrix (soil, water and tree leaves) and a long range transportation of air mass. But the former affected OCPs concentration more than the latter. The degradation rate constants (k) of OCPs calculated using multiple regression analysis and revised standard temperature method were in good agreement each other. The value of k of ${\gamma}-HCH$ was very low as -0.0007, but the range of k of other components were $-0.00l8{\sim}-0.0038$. The half-life $({\tau})$ which was calculated by k of ${\gamma}-HCH$ was 2.6 years-the longest one, but that of heptachlor epoxide was in 0.5 year-the shortest one. $({\tau})\;of\;{\alpha}-chlordane,\;{\gamma}-chlordane$ and trans-nonachlor in technical chlordane was 1.0, 1.1 and 0.7 year respectively.

Current status of research on radionuclides used in nuclear mediccine (중성자선 실험 및 발암연구의 현황과 미래)

  • Kim, Hui-Seon
    • Radioisotope journal
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    • v.21 no.3
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    • pp.46-60
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    • 2006
  • In recent years the progress of nuclear medicine advanced dramatically in imaging and targeted radionuclide therapy is able to open op exciting perspectives as standard diagnostic and therapeutic modalities, complementing conventional modalities. Positron emission tomography/computed tomography (PET/CT) technology with FDG has been developed clinically in less than 10 years as a routine standard in oncological imaging, including a number of other fluorinated radiopharmaceuticals being evaluated for their ability to complement FDG. However, the limitation of FDG-PET such as non-specific uptake and its short half-life is not compatible with the time necessary for optimal tumour targeting. Therefore, a development of innovative positron-emitting radionuclides with half-lives longer than 10 h is needed. For therapeutic applications, the injection of higher activities is required to reach efficient adsorbed doses in radioresistant solid tumours, while limiting the irradiation of vital organs. In this application, the longer half-life of radiolsotopes are more fit well for radionuclide therapy. To achieve this, researches have to be carried in a largor spectrum of radionuclides for diagnosis and therapy. In the context of rapidly growing nuclear medicine and strong demanding innovative radionuclides, a high-energy (100 MeV), high-intensity (-mA) accelerator with proton (PEFF at KAFRI). will be operating in 2011. The priorities of PEFP will include supporting the nuclear medicine research community by providing those radionuclides with current limited availability by means of a high-energy, high-intensity accelerator.

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