• Preventive Nutrition and Food Science
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• v.19 no.3
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• pp.136-144
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• 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. This study was conducted to evaluate the effects of Platycarya strobilacea S. et Z. (PSE) extract on mouse hair growth and to determine the mechanism of action of PSE. PSE was purchased and its antioxidant activities, such as electron donating ability, total polyphenol content, and flavonoid content were tested. Toxicity during topical treatment was determined by the CCK-8 assay, a cell viability test. Fifteen 4-week-old male C57BL/6 mice were assigned to receive one of three treatments: dimethyl sulfoxide (negative control), minoxidil (positive control) or PSE. Test materials were topically applied to the shaved dorsal skin of each mouse daily for 3 weeks. After 21 days, we observed skin tissue hair follicle morphology and length, mast cell number, and stem cell factor (SCF) expression using hematoxylin and eosin (H&E), toluidine blue, and immunohistochemical staining, respectively. Furthermore, the expression of cytokines involved in hair growth [i.e., insulin-like growth factor (IGF)-1, keratinocyte growth factor (KGF), and transforming growth factor (TGF)-${\beta}1$] was determined by PCR. PSE was found to have very high antioxidant activity. The cell viability rate of PSE-treated mice was markedly higher than that of mice in the control group. We also observed an increase in hair follicle length, strong SCF staining, and a decrease in mast cell number in the PSE group. In addition, PSE-treated mice had higher IGF-1 and KGF expression and lower TGF-${\beta}1$ expression than mice in the minoxidil-treated group. These results suggest that topical application of PSE promotes hair growth by intensifying SCF, suppressing mast cell production, and increasing hair growth-promoting cytokine expression.

• Journal of the Korean Society of Clothing and Textiles
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• v.29 no.8 s.145
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• pp.1079-1091
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• 2005

The purpose of this study was to point out the unification of the size of swimming headgear by measuring detailed measurement of head ferm and systematizes the head form. A total of 300 male and female Korean adults aged from 18 years old to 35 years old were measured through the direct measurement method. This study attempted to identify the head form of male and female adults using measurement data and the head form was classified through factor analysis and cluster analysis. (1) Based on the fact that this study especially focuses on the size of swimming headgear, factor analysis was performed far both direct measurements with hair and without hair. For the measurements with hair, seven factors were extracted. They were head thickness factor, head width factor, width of side head factor, height of back head factor, length of front head factor, circumference of front head factor, thickness of front head factor and head height factor. They explained the $70.95\%$ of the measurements. (2) The cluster analysis was executed to classify the somatotype of the korean head form on the basis of similarity. According to the cluster analysis result, the measurements with hair categorized types, 'Woman's long-hair type', 'Small type', 'Long and flat type', 'Large type'. (3) Head circumference B and Left tragion - Vertex - Right tragion circumference which are generally length and width in choosing swimming headgear size were selected as measurement items far size of swimming headgear. Direct measurements and sizes of four swimming headgear with different materials taking into account their elongation rate were also compared.

• Journal of the Korean Geotechnical Society
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• v.31 no.6
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• pp.15-25
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• 2015

This study aimed at the strength increase of the soft ground and analyzed the strength characteristics of clay soil reinforced with hair fiber which is environmentally friendly. The study varied the length of hair fiber, the amount of hair fiber, the amount of cement, and curing days to investigate both the compressive and tensile strengths and the stress-strain relationship of hair fiber mixed clay soils. The test results indicated that both the compressvie and tensile strengths increased with hair fiber mixed, especially in the tensile strength. In addition, the hair fiber mixed clay soil allowed larger displacement to failure. Based on the test results, it is thought that the environmentally friendly hair fiber could be utilized practically to increase the clay strength in the future.

• Nutritional Sciences
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• v.8 no.4
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• pp.262-267
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• 2005

Reactive oxygen species can be generated in the skin by hair dyeing. The aim of this study was to find out the effects of the oxidative-type hair dye application in young women on the antioxidant systems. We investigated the lipid peroxide levels, glutathione (GSH) levels, and the antioxidant enzyme activities including superoxide dismutase (SOD), glutathione peroxidase (GSHPx) in plasma and erythrocytes and catalase (CAT) in erythrocytes, and DNA damages in lymphocytes. Also, plasma concentrations of antioxidant vitamins, vitamin A and E, were measured and the correlations between various antioxidant parameters and oxidative damages were evaluated The antioxidant enzyme activities in plasma (GSHPx) and in erythrocytes (SOD and CAT) were decreased significantly after hair dyeing. 1be lipid peroxide and GSH levels were not affected in both plasma and erythrocytes. No significant difference was found in the concentrations of both vitamin A and E between before and after hair dyeing. However, DNA damages expressed as the tail extent moment (TEM) and tail length (TL) were significantly (p<0.001) increased. The plasma vitamin E concentration was correlated with DNA damages (TEM: r=-0.590, p<0.01 and TL: r=-0.533. p<0.01) and RBC SOD activity (r=0.570, p<0.05). In turn, RBC SOD activity was significantly correlated with both plasma MDA levels (r=-0.412, p<0.05) and DNA damages (TM: r=-0.546, p<0.01, TL: r=-0.493, p<0.01). Our results demonstrated that the exposure to hair dyeing produced lymphocyte DNA damage and modification of the antioxidant enzyme activities. Also, there were very strong associations between plasma vitamin E concentration, RBC SOD activity and DNA damage induced by hair dyeing. It suggests that the antioxidant status of a subject is likely to be related to the extent of the harmful effects caused by hair dyeing.

• Journal of Fashion Business
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• v.6 no.3
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• pp.41-51
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• 2002

The author of the paper investigated the changes of hairstyle along the developments in hairdressing industry in the 20th century. The development process of hairdressing industry was divided into four periods of introduction, origination, growth, and establishment. The corresponding changes of hairstyle were analyzed and the findings are as follows. 1. Hairstyle could be classified into such typical ones as traditional style, cut, bob, wave, permanent wave, up style, and hair coloring. 2. Fashion leaders affected the changes of hairstyle. 3. Whenever hairdressing appliances were introduced, new hairstyle was practiced as follows with the use of the appliances. (1) Introduction Period - Traditional Style : Chignon, pigtail ribbon $\rightarrow$ Variations were designed in hair length or split due to the limited availability of appliances. - Up Style : Pompadour, thick and up hair, encircling hair $\rightarrow$ Padding was used for sweep-up. (2) Origination Period - Bob Style : Women's first bob style. - Wave style : Wave with bob, close-cropped hair, up style $\rightarrow$ Iron, set, permanent devices were used. (3) Development Period - Wave Style : Wind wave, easily manageable wave $\rightarrow$ Blow dry, body permanent were used. (4) Establishment Period - Straight Style : Use of straight permanent. - Thick Wave Style : Development of various kinds of rod. - Hair Coloring : Advent of diverse fashion hair coloring, apart from the coloring of white hair, with the introduction of color TV. - Bob Style : Romantic bob style $^{\circ}\hat{E}$ Use of clippers and thinning scissors. Thus, the changes of hairstyle according to the development in hairdressing industry had close relationship with the improvement in hairdressing appliances.

• Korean Chemical Engineering Research
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• v.44 no.1
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• pp.58-64
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• 2006

We successfully isolated human anagen hair follicles from human scalp skin by microdissection and tried to culture them under various conditions. First we confirmed negative effect of serum on human hair follicle organ culture. As a next step serum-free medium compositions, Philpott medium, IMDM, and DHGM (Dongguk hair growth medium) were tried. Philpott medium is a general medium for hair organ culture based on Williams' E medium and DHGM is a special self-developed medium containing high amino acids and vitamins (B group) composition. As results, hair follicle in Philpott medium and IMDM showed anagen phase morphological structure, but rapid loss of hair elongation, low alkaline phosphatase expression, and very low expression of CK19. It is thought these hair follicles rapidly regressed from apoptosis. However, hair follicles in DHGM showed long term anagen phase morphological structure, continuous hair elongation, high alkaline phosphatase, and CK19 expression. These results demonstrate that high amino acids and vitamins (B group) composition are essential to in vitro long term human hair follicle organ culture and this culture medium will be useful in basic study of hair biology or application study to the development of alopecia treatment drugs.

• Journal of the Korean GEO-environmental Society
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• v.17 no.2
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• pp.23-29
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• 2016

This study was carried out with a view to increasing the tensile strength of sand soil and examined the characteristics of the tensile strength of sand soil reinforced by hair fiber which is environmentally friendly. The study investigated the change of the tensile strength and the stress-strain relationship varying the length of hair fiber, the amount of hair fiber, the amount of cement, and curing days. The test results indicated that the tensile strength increased significantly with hair fiber mixed. In addition, the sand soil mixed with hair fiber had larger displacement at failure. Based on the test results, it is appeared that the environmentally friendly hair fiber could be utilized practically to increase the tensile strength of sand soil in the future.

• KSBB Journal
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• v.31 no.4
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• pp.237-245
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• 2016

Hair loss affects both men and women of all ages and often significantly affects social and psychologic health. Recent therapeutic approach for hair loss such as finasteride and minoxidil focused on regulation of hormonal system blood flow. However, long-term use of these drugs caused adverse effects. To develop herbal medicine for therapeutic effect on hair growth, here we screened the 10 medicinal herbs (Red ginseng, Licorice, Ulmus, Barberry root, Lycium root, Rehmanniae radix crudus, Sophora root, Sweet flag, Polygala root, Achyranthes) based on oriental medicine literature. We measured cytotoxicity, anti-oxidant activity, and $5-{\alpha}$ reductase inhibitory effect of the herbal medicine on human dermal papilla (DP) cells to investigate therapeutic effect of the herbal medicine. Treatment of the 1% herbal medicine did not show any cytotoxic effects, and cell growth was increased by treatment of the 0.1% herbal medicine. In addition, the herbal medicine showed stronger antioxidant activity than resveratrol and comparable inhibitory activity of $5-{\alpha}$ reductase with finasteride. Furthermore, when applied to in vivo mouse model, we also observed increases in the number and length of hair of the herbal medicine-treated group. These results suggest that the herbal medicine promotes hair growth by its antioxidant activity and inhibitory activity of $5-{\alpha}$ reductase and might therefore be a promising hair growth-promoting agent.

• Asian-Australasian Journal of Animal Sciences
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• v.27 no.9
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• pp.1355-1359
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• 2014

To detect goat vascular endothelial growth factor (VEGF)-mediated regrowth of hair, full-length VEGF164 cDNA was cloned from Inner Mongolia cashmere goat (Capra hircus) into the pET-his prokaryotic expression vector, and the recombinant plasmid was transferred into E. coli BL21 cells. The expression of recombinant $6{\times}his-gVEGF164$ protein was induced by 0.5 mM isopropyl thio-${\beta}$-D-galactoside at $32^{\circ}C$. Recombinant goat VEGF164 (rgVEGF164) was purified and identified by western blot using monoclonal anti-his and anti-VEGF antibodies. The rgVEGF164 was smeared onto the dorsal area of a shaved mouse, and we noted that hair regrowth in this area was faster than in the control group. Thus, rgVEGF164 increases hair growth in mice.

• Journal of the Korean GEO-environmental Society
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• v.19 no.4
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• pp.17-26
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• 2018

This study systematically examines the changes in the compressive and tensile strength of soil cement reinforced by natural hair fiber, which is regularly produced from human. Extensive experimental tests of various test specimens have been carried out in a laboratory. Several factors are considered, including the soil type, amount of cement, amount of fiber, fiber length, loading type, and curing age. The test results indicate that both the compressive and tensile strengths are significantly affected by the fiber, either increasing or decreasing depending on the conditions. The increase in tensile strength is significant in the sand-based soil cement due to the tensile resistance of the fiber which is interlocked with the surrounding soil or cement particles. The natural fiber provides a larger strain to failure due to its extensibility, which allows greater deformation. Based on the test results, natural hair fibers can be an effective and environmentally friendly way to improve soil ground subjected to tensile loading, such as an embankment slope, road subgrade, or landfill, thus reducing the cost for cement and waste treatment. The study results provide a useful information of better understanding the mechanical behavior of natural hair fiber in soil cement and the practical use of waste materials in civil engineering. The findings can be practically applied for improving earth structures under tensile loading.