• Journal of Preventive Medicine and Public Health
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• 제35권4호
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• pp.275-281
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• 2002

Objectives : To evaluate the DNA damage by hair dyeing in human lymphocytes Methods : Comet assays were carried out to evaluate the DNA damage in lymphocytes by hair dyeing. Twenty subjects were selected from women volunteers whose age ranged from 55 to 67 year old. All subjects had no smoking history. Blood samples were collected before and 6 hours after hair dyeing. DNA damage was evaluated by means of the tail moments, which were quantified by a KOMET 4.0 image analysis system. Results : The tail moments before hair dyeing showed no significant differences among subjects except for the high frequency group. The mean values of the tail moments in subjects with low and high frequencies of hair dyeing were 1.39 and 1.77, respectively (p<0.05). The tail moments after hair dyeing increased significantly, The mean values of tail moments in subjects before and after hair dyeing were 1.45 and 1.79, respectively (p<0.01). However, the difference levels of DNA damage in lymphocytes before and after hair dyeing were found to be slightly lower in both the dietary supplement taking group and high frequency group. Conclusions : The high frequency group appears to have a higher level of DNA damage than the low frequency group before hair dyeing. DNA damage in lymphocytes was found to be significantly higher in the volunteers after hair dyeing. In this study, the related factors such as high frequency and taking dietary supplements appeard to reduce DNA damage in lymphocytes after hair dyeing.

• 디지털융복합연구
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• 제17권1호
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• pp.357-364
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• 2019

본 연구는 모발 탈색 시 사용되어지는 탈색제 입자에 따른 모발 손상도를 비교하였으며, 주사전자현미경을 사용하여 세 가지의 탈색제 입자크기를 관찰하였다. 탈색제의 주성분은 과황산암모늄과 과황산칼륨이 주성분인 분말형 탈색제로 각 제품 입자크기는 $131{\mu}m$, $72{\mu}m$, $48.8{\mu}m$로 나타났다. 손상도 실험에서 입자가 큰 탈색제보다는 입자가 작은 시술 제품에서 큐티클 층이 일어나거나 박리현상이 거의 일어나지 않았다. 모발의 색상 측정에서 입자 큰 탈색제의 모발시료는 가장 어둡게 나왔으며, 가장 작은 입자의 탈색 결과가 가장 밝게 나왔다. 연구 결과 모발의 손상도 완화에 더 효과적인 탈색제는 작은 입자를 가진 탈색제를 이용하여 시술하고, 탈색 정도에 따라 입자를 선택하는 것이 탈색력은 높이고 손상도를 낮출 수 있다고 사료된다. 이는 탈색제 선택에 대해서 우수한 결과를 만들기 위한 방안이며, 그 결과를 토대로 현장에서 탈색 시술시 모발 손상에 대처할 수 있을 것으로 기대 된다.

• 대한약침학회지
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• 제19권2호
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• pp.122-128
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• 2016

Objectives: Cornu cervi pantotrichum (CCP) has been widely used in Korean and China, as an anti-fatigue, anti-aging, and tonic agent to enhance the functions of the reproductive and the immune systems. Because CCP has various growth factors that play important roles in the development of hair follicles, we examined whether CCP pharmacopuncture solution (CCPPS) was capable of promoting hair growth in an animal model. Methods: One day after hair depilation, CCPPS were topically applied to the dorsal skin of C57BL/6 mice once a day for 15 days. Hair growth activity was evaluated by using macro- and microscopic observations. Dorsal skin tissues were stained with hematoxylin and eosin. Expressions of bromodeoxyuridine (BrdU), proliferating cell nuclear antigen (PCNA), and fibroblast growth factor (FGF)-7 were examined by using immunohistochemical staining. A reverse transcription polymerase chain reaction (RT-PCR) analysis was also conducted to measure the messenger RNA (mRNA) expression of FGF-7. Results: CCPPS induced more active hair growth than normal saline. Histologic analysis showed enlargement of the dermal papilla, elongation of the hair shaft, and expansion of hair thickness in CCPPS treated mice, indicating that CCPPS effectively induced the development of anagen. CCPPS treatment markedly increased the expressions of BrdU and PCNA in the hair follicles of C57BL/6 mice. In addition, CCPPS up regulated the expression of FGF-7, which plays an important role in the development of hair follicles. Conclusion: These results reveal that CCPPS facilitates hair re-growth by proliferation of hair follicular cells and up-regulation of FGF-7 and suggest that CCPPS can potentially be applied as an alternative treatment for patients with alopecia.

• 한국응용과학기술학회지
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• 제39권3호
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• pp.471-478
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• 2022

본 연구는 손상된 모발의 개선 효과를 알기 위해 바바수오일을 첨가한 모질 개선 제형제를 제조 후 손상된 모발에 도포하여 실험 하였다. 실험 원료로 바바수오일 함량을 0 g, 3 g, 6 g, 9 g 으로 다르게 하여 펌 베이스제에 첨가하였다. 제조한 제형제로 8레벨의 탈색한 시료 모발에 도포하여 각 시료와 손상모를 측정하여 비교 분석하였다. 측정방법은 모질 개선 효과를 알기 위해 인장강도, 메틸렌블루를 이용한 흡광도, 광택을 측정하였다. 연구결과의 신뢰성을 위해 통계분석을 하였다. 연구결과로 인장강도 측정결과는 바바수오일을 첨가하여 도포 한 모든 시료에서 손상모보다 인장강도가 증가함을 알 수 있었다. 메틸렌블루를 이용한 흡광도 분석결과 모든 시료에서 손상모보다 흡광도가 감소함을 알 수 있었다. 광택 측정결과는 모든 시료에서 손상모보다 광택이 증가함을 알 수 있었다. 결론은 바바수오일이 손상된 모발에 개선 효과가 있는 것을 알 수 있었다.

• 패션비즈니스
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• 제6권2호
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• pp.67-76
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• 2002

This research examines the characteristic trends through analysis on cue in the contemporary fashion distinctly and systematically. It is carried out by both qualitative analysis and quantitative analysis. In the qualitative analysis, the four important street fashions of neo-mods/jazz, neo-hippie/grunge, sportivecasual and technos/cyber-punk are grouped. In the quantitative analysis, statistical data are sampled from Collection II of the 1990s S/S. It takes frequency, percentage, $\chi^2$-test and etc. by using the comprehensive tools for statistical treatment. There were significant differences between the S/S fashion. According to the cues, there are also significant differences between the fashion in the 1990s. In 'Neo-Mos/Jazz' style shows highly androgynous look, deep and strong tone, green/blue colors, natural fabric, stripe pattern, long hair style, and hided make-up. 'Neo-hippie/gnenge' style shows highly folklore look, vivid tone purple colors, seethrough/knit fabric, natural /traditional pattern, decorative hair special makeup. 'Sportive casuals' style shows highly sportive look, greish tone, white/grey colours, natural fabric, solid patten, bobbed hair, and natural make-up. 'Techno/cyber punk style shows highly comocorps look, pale tone black colors avangard fabric, solid patten, punk/dyed hair special make-up.

• 한국염색가공학회지
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• 제21권5호
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• pp.1-9
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• 2009

The feasibility of earthworm protease as a new cosmetic material for human hair care was investigated. The effectiveness of the earthworm protease treatment was assessed by thickness change of hairs, optical microscope examination, aminoacid analysis, surface morphology, angular resolution analysis through methylene blue staining method and tensile strength change. The protease treated hair became thinner and the soil on the surface removed in experimental groups unlike control group. Tensile strength decreased in experimental group in which the enzymes may decompose polypeptide bonds.

• 한국의상디자인학회지
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• 제13권2호
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• pp.35-46
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• 2011

The purpose of this study was to investigate the effect of mass media on women's clothing image, make-up image, and hair image. The subjects of the study were 306 women who lived in Gyeongnam area. Data were collected during June in 2009. Statistical analysis used in this study were frequency, F-test, t-test, Duncan test, factor analysis, Cronbach's ${\alpha}$, correlation coefficient, and multiple regression. The results of this study were as follows. The mass media according to the demographic characteristic of women showed significant difference. Three factors of clothing image were titled as elegance, youth, and visibility. Three factors of make-up image were titled as modern, romanticism, and mediocrity. Four factors of hair image were titled as attraction, individuality, gentleness, and cuteness. The mass media resulted in correlation with the clothing image, make-up image, and hair image. The mass media had a influence on the clothing image, make-up image, and hair image. The study results are highly expected to be used as useful sources in one's image formation and a marketing plan.

• 한국식품영양학회지
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• 제21권2호
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• pp.256-262
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• 2008

This study was carried out to compare the hair mineral status of obese, over-weighted and non-obese individuals, to gather basic data for customizing menu development and to create an education manual for the obese persons. Food preferences or various disease states could be suggested by different mineral patterns in TMA(tissue mineral analysis). The results indicated that Zn status was considerably lower in the obese individuals than in the non-obese(p<0.001) whereas hair Na(p<0.0001), K(p<0.01) and Fe(p<0.05) were at significantly higher levels in the obese individuals. The ratio of Ca/K(p<0.001) was significantly lower in the obese than in the non-obese. But the levels of hair toxic minerals such as Sb, As, Hb, Al et al. were not differ according to BMI groups. The obtained data demonstrate the changes of hair mineral content in both overweight and obese individuals thus suggesting metabolic mineral disturbance in those groups.

• 대한약침학회지
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• 제24권4호
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• pp.182-190
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• 2021

Objectives: The purpose of this study was to analyze the microneedle therapy system (MTS) and its research methods for the past 10 years in Korea. Methods: Data on microneedle therapy system were collected using NDSL, KISS, RISS, and OASIS electronic databases from January 2010 to August 2021. "microneedle," "derma stamp," "microneedle therapy system" were used as the keywords. The present study, however, excluded data that were 1) unrelated to the microneedle therapy system, 2) from review/meta/protocol studies, and 3) from overseas studies. Data selected through the primary screening process, animal studies, case reports, and clinical data were included in the analysis. However, information data not related to the microneedle therapy system were excluded from the study. Results: Among the MTS-related papers published from January 2010 to August 2021, 7 animal research, 2 clinical trials, and 10 case studies were published. Based on the research topics, there were 8 papers on skin improvement and skin diseases, 7 papers on hair growth and hair loss, 3 papers on stability, and 1 paper on peripheral facial paralysis. Conclusion: Most of the studies related to MTS focused on skin, hair, and stability. The effect of MTS on hair growth and skin improvement has been confirmed, and it has been proven to have significant effects on the treatment of acne, acne scars, and hair loss in clinical practice. No serious side effects were observed during the MTS treatment, and the safety assessment confirmed that it was safe for use.

• 한국임상약학회지
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• 제21권3호
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• pp.256-269
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• 2011

Omega-3 fatty acids are a specific type of unsaturated fat that the body cannot manufacture on its own, so they must be obtained from food which is essential fatty acids (EFAs). Omega-3 fatty acids consist of three types which are a-Linolenic Acid (ALA), Eicosapentaenoic (ELA), and Docosahexaenoic Acid (DHA). Especially, EFAs help to prevent skin and hair drying, acne, eczema, prevention from allergies, brittle nails, rashes, and tiny lumps. The aim of this study is to investigate improvement and protection for hair damaged by chemical treatment with omega-3 formulated shampoo. We selected virgin hair sample and divided into two groups for bleaching once and three times and then damaged hair by changing the number of hair bleaching (twice with interval of 15 minutes). Each bleached hair was treated by five different kinds of shampoo (Control, Horse shampoo, DHA shampoo, EPA shampoo, Omega-3 shampoo mixture). Apart from this, EPA/DHA 2, 5, 8, 10 and 12% shampoo were prepared and treated to hair for comparing rate of progress in damaged hair. To quantify improved condition of damaged hair, we performed Scanning Electron Microscope (SEM) for ultrastructure of damaged hair fraction, measurement of thickness change and BCA Protein Assay for recovery rate of damaged hair. The moisture in hair was measured by Thermal analysis machine. In results, we observed the particle of hair surface damaged by bleaching treatment were well improved with treatment with EPA and DHA shampoo. Also, quantity of protein was lowered with higher concentration of EPA & DHA i.e., 8 and 12 % then compared with horse oil shampoo in three times treatment group. It shows that bleached hair have been recovered by treating rapidly and get protective coat. In conclusion, EPA and DHA shampoo improved damaged hair, especially with EPA / DHA 12% shampoo. Also, EPA shampoo could protect the damaged hair depending on increasing concentration of EPA. Therefore, we conclude omega-3 shampoo could make damaged hair protect and get healthy hair environment.