• International Journal of Industrial Entomology and Biomaterials
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• v.12 no.2
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• pp.69-73
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• 2006

To elucidate the composition of bumblebee (Bomb us terrestris) venom (BBV) and the anti-inflammatory effect of BBV. The major components of BBV by LC chromatography and SDS-PAGE were identified. The production of nitric oxide (NO) and proinflammatory cytokines was examined by lipopolysaccharide (LPS) in a macrophage cell line, RAW 264.7 cells, with BBV. BBV inhibits LPS-induced NO in a dose dependent manner. We also found that BBV inhibits proinflammatory cytokine, tumor necrosis factor (TNF)-${\alpha}$ and interleukin (IL)-6 production. These findings mean that BBV can be used in controlling macrophages mediated inflammation related disease. Additional studies on the pharmacological aspects of the individual components of BBV are recommended for future trials.

• Proceedings of the Korean Society of Life Science Conference
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• 2005.09a
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• pp.55-55
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• 2005

• Proceedings of the KSAR Conference
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• 2004.06a
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• pp.214-214
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• 2004

Follicle stimulating hormone (FSH) is a pituitary glycoprotein composed of two post translationally modified subunits, which must properly assemble to be biologically active. We developed a transgenic (TG) mouse model that overexpresses the human Follicle-Stimulating hormone (FSH) -subunit under the bovine -casein promoter, displaying in females an excessive levels express in mammary gland. (omitted)

• Proceedings of the KSAR Conference
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• 2004.06a
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• pp.226-226
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• 2004

Circling (cir) mouse is a spontaneous mutant in the inner ear that was first reported in Korea. The mutation is transmitted by an autosomal recessive gene with 100 %- penetrance.. Homozygous mice are characterized by head-tossing, bi-directional circling behavior and deafness. Histologicalexamination of the inner ear reveals abnormalities of the region around the organ of Corti, spiral ganglion neurons, and outer hair cells. (omitted)

• The Korean Journal of Rehabilitation Nursing
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• v.7 no.2
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• pp.179-187
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• 2004

Purpose: This study was performed to assess the degree of cognitive function of elderly by MMSE-K performances and of that effect. Method: The subjects were 185 aged over 65 in Daejeon Metropolitan city. Data were collected through personal interview using the questionnaire from 10 to 31, Jan. 2003. The measures were Korean version of Mini-Mental State Examination(MMSE-K). Results: The mean score of MMSE-K was $22.60{\pm}5.39$. The prevalence of cognitive impairment was estimated as 48.6% by MMSE-K ${\leq}23$ and significantly age, gender, and education effect. The subtype score of MMSE-K were significantly lower in female group in each items : orientation in time and place, attention/calculation, language except registration and recall. And the scores were significantly lower in the older group and non-educated group in the all items of MMSE-K. Conclusion: Gender, age, and education showed significant effects on total and subtype MMSE-K score. Cognitive function decline were higher in female, older age group, and non-educated group. Therefore, those three factors are thought to be one of important risk factors for development of dementia, also it is assumed to be affected by other variables than age, gender, education effect.

• Journal of Acupuncture Research
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• v.29 no.5
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• pp.177-185
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• 2012

Objectives : The objective of this case report was to observe the effect of musculoskeletal ultrasound-guided acupotomy therapy on common peroneal nerve palsy. Methods : From June, 2010 to September, 2012, 3 patients clinically diagnosed as common peroneal nerve palsy were treated with general oriental medicine therapy (acupuncture, pharmacopuncture, moxibustion, cupping, physical therapy, herbal medication) and acupotomy. Results : The foot drop of the patients was remarkably improved. Conclusions : This study demonstrates that oriental medical treatment with acuputomy therapy hasnotable effect in improving symptoms of common peroneal nerve palsy. As though we had not widly experienced in this treatment, more research is needed.

• Journal of Korean Society for Atmospheric Environment
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• v.11 no.2
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• pp.137-144
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• 1995

The I.A.P.(Index of Atmospheric Purity) by the distribution of Bryophtes on the bark of various latifoliate tree trunks was investigated at four sites(Daeheung, Songkwang, Jeungsim, and Heunggook Temple) from April, 1991 to April, 1993. The IAP was in inverse proportion to the degree of air pollution. The I.A.P at four sites were estimated 78.2 at Daeheung temple, 61.0 at Songkwang temple, 28.3 at Jeungsim temple, and 10.3 at Heunggook temple, respectively. The distribution degree of Bryophytes in Heunggook temple progressed during the last ten years. It represents the bettrment of air quality. Bioassay by means of lichens seems to have great potential for better and less expensive ways of measuring pollution levels instead of the high cost of buying and maintaining air pollution monitoring equipment.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.19 no.7
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• pp.500-511
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• 2007

The Optimal solutions of the design variables in internally finned tubes have been obtained for three-dimensional periodically fully developed turbulent flow and heat transfer. For a trapezoidal fin profile, performances of the heat exchanger are determined by considering the heat transfer rate and pressure drop, simultaneously, that are interdependent quantities. Therefore, Pareto frontier sets of a heat exchanger can be acquired by integrating CFD and a multi-objective optimization technique. The optimal values of fin widths $(d_1,\;d_2)$, fin height(h) and helix angle$(\gamma)$ are numerical1y obtained by minimizing the pressure loss and maximizing the heat transfer rate within ranges of $d_1=0.5\sim1.5mm$, $d_2=0.5\sim1.5mm$, $h=0.5\sim1.5mm$, and $\gamma=0\sim20^{\circ}$. For this, a general CFD code and a global genetic algorithm(GA) are used. The Pareto sets of the optimal solutions can be acquired after $30^{th}$ generation.

• Proceedings of the PSK Conference
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• 2001.10a
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• pp.323-323
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• 2001

• Journal of Korean Academy of Nursing Administration
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• v.21 no.5
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• pp.552-560
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• 2015

Purpose: This study was performed to identify the mediating effect of empowerment in the relationship between head nurses' servant leadership and organizational commitment among clinical nurses. Methods: A cross-sectional survey design was used. A convenience sample of 249 nurses was recruited from three hospitals located in J province, South Korea. Data were collected by self-report questionnaires, including general characteristics, servant leadership, empowerment, and organizational commitment. Data were analyzed with descriptive statistics, Pearson correlation coefficients, independent t-test, One-way ANOVA, and linear regression using the SPSS 22.0 program. Results: Head nurses' servant leadership perceived by clinical nurses significantly influenced their organization commitment. Empowerment partly mediated the effect of servant leadership on organizational commitment. Conclusion: The findings suggest the importance of improving nurse managers' servant leadership and empowering nurses to increase their organizational commitment.