• KSBB Journal
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• v.24 no.4
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• pp.410-414
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• 2009

Single-nucleotide polymorphisms (SNPs) are the DNA sequences difference among the same species in the level of nucleic acids and are widely applied in clinical fields such as personalized medicine. The routine and labor-intensive methods to determine SNPs are performing the sequence homology search by using BLAST and navigating the trace of chromatogram files generated by high-throughput DNA sequencing machine by using Chromas program. In this paper, we developed SNPchaser, a web-based program for detecting SNPs substitution and heterozygosity existence, to improve the labor-intensive method in determining SNPs. SNPchaser performed sequence alignment and visualized the suspected region of SNPs by using user's reference sequence, AB1 files, and positional information of SNPs. It simultaneously provided the results of sequences alignment and chromatogram of relevant area of SNPs to user. In addition, SNPchaser can easily determine existence of heterozygosity in SNPs area. SNPchaser is freely accessible via the web site http://www.bioinformatics.ac.kr/SNPchaser and the source codes are available for academic research purpose.

• Proceedings of the Korea Water Resources Association Conference
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• 2009.05a
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• pp.1797-1801
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• 2009

수문자료 정보시스템은 설마천 시험유역의 신뢰성 있는 수문자료를 체계적으로 저장하고 관리하며, 간단한 가입절차를 통해 사용자에게 온라인으로 신속하게 제공하는 시스템이다. 설마천 시험유역은 관측망 설계가 이루어진 1995년부터 현재까지 지속적으로 운영되고 있으며, 본격적으로 2000년부터 신뢰할 만한 관측자료가 생성되어 왔다. 구축된 설마천 시험유역의 수문자료 정보시스템은 1996년부터 현재까지 생성된 관측자료와 가공자료로 구성되어 있다. 관측자료에는 실시간-시계열 자료(6개소 우량, 2개소 하천수위, 1개소 유량), 비실시간-시계열자료(5개소 우량, 2개소 3종의 하천수위, 2개소 지하수위, 1개소 파샬플륨 수심, 1개소 14종의 기상), 비실시간-비시계열 자료(3개소 유량측정성과, 3개소 수질, 2개소 부유사량) 등이 있으며, 가공자료에는 2개소 유역면적우량, 2개소 유량환산자료가 있다. 관측된 자료는 수문자료 처리절차에 따라 비교·검토를 통하여 자료를 확정시킨다. 확정된 자료는 새로운 설마천 시험유역 홈페이지(http://seolmacheon.kict.re.kr)를 통해 간단한 등록을 한 후 필요로 하는 자료를 검색하여 추출할 수 있다. 제공되는 자료에는 6개 지점우량, 2개소 유역면적우량, 2개소 하천수위, 2개소 지하수위, 2개소 유량, 1개소 18종의 기상, 3개소 유량측정성과, 3개소 수질, 2개소 부유사량 자료 등이 있다. 설마천 시험유역에서 축적된 수문자료는 본 시스템을 통하여 널리 사용자에게 쉽게 제공이 가능함에 따라 자료의 이용도가 크게 증대될 것이며, 동시에 자료의 공유는 자료의 검증을 확보할 수 있을 것이다. 따라서, 자료의 공유와 검증이 이루어진 수문자료는 수자원 연구 및 개발 분야에 직접적인 이용이 가능할 것으로 기대된다.

• Asian-Australasian Journal of Animal Sciences
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• v.21 no.2
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• pp.155-160
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• 2008

Several studies have reported quantitative trait loci (QTL) for meat quality on porcine chromosome 2 (http://www.animalgenome.org/QTLdb/pig.html). For application of the molecular genetic information to the pig industry through marker-assisted selection, single nucleotide polymorphism (SNP) markers were analyzed by comparative re-sequencing of polymerase chain reaction (PCR) products of 13 candidate genes with DNA from commercial pig breeds such as Berkshire, Yorkshire, Landrace, Duroc and Korean Native pig. A total of 34 SNPs were identified in 15 PCR products producing an average of one SNP in every 253 bp. PCR restriction fragment length polymorphism (RFLP) assays were developed for 11 SNPs and used to investigate allele frequencies in five commercial pig breeds in Korea. Eight of the SNPs appear to be fixed in at least one of the five pig breeds, which indicates that different selection among pig breeds might be applied to these SNPs. Polymorphisms detected in the PTH, CSF2 and FOLR genes were chosen to genotype a Berkshire-Yorkshire pig breed reference family for linkage and association analyses. Using linkage analysis, PTH and CSF2 loci were mapped to pig chromosome 2, while FOLR was mapped to pig chromosome 9. Association analyses between SNPs in the PTH, CSF2 and FOLR suggested that the CSF2 MboII polymorphism was significantly associated with several pork quality traits in the Berkshire and Yorkshire crossed F2 pigs. Our current findings provide useful SNP marker information to fine map QTL regions on pig chromosome 2 and to clarify the relevance of SNP and quantitative traits in commercial pig populations.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.19 no.4
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• pp.51-61
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• 2009

Recently, the cyber-attacks using botnets are being increased, Because these attacks pursue the money, the criminal aspect is also being increased, There are spreading of spam mail, DDoS(Distributed Denial of Service) attacks, propagations of malicious codes and malwares, phishings. leaks of sensitive informations as cyber-attacks that used botnets. There are many studies about detection and mitigation techniques against centralized botnets, namely IRC and HITP botnets. However, P2P botnets are still in an early stage of their studies. In this paper, we analyzed the traffics of the Peacomm bot that is one of P2P-based storm bot by using honeynet which is utilized in active analysis of network attacks. As a result, we could see that the Peacomm bot sends a large number of UDP packets to the zombies in wide network through P2P. Furthermore, we could know that the Peacomm bot makes the scale of botnet maintained and extended through these results. We expect that these results are used as a basis of detection and mitigation techniques against P2P botnets.

• Journal of Acupuncture Research
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• v.25 no.2
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• pp.179-187
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• 2008

Objectives : The purpose of this study is to review the acupuncture treatment studies of tic disorder in traditional chinese medicine. Methods : We reviewed the 16 studies about acupuncture treatment of tic disorder which were published from 2005 through 2007. We selected those studies from CNKI(中國知識基礎設施工程 http://www.cnki.net). Results : Selected 16 studies were divided into 8 case reports and 8 control studies. CCMD(6 studies) and DSM(4 studies) were frequently used in the diagnosis of tic disorder. Acupuncture points frequently used were 百會(Baekhoe, $GV_{20}$), 太衝(Taechung, $LR_3$), 風池(Pungji, $GB_{20}$), 合谷(Hapgok, $LI_4$), 神門(Sinmun, $HT_7$), 三陰交(Sameumgyo, $SP_6$), 內關(Naegwan, $PC_6$) and so on. According to specific parts of symptom, some acupuncture points were added. Most of studies reported that acupuncture treatments of tic disorder were very effective. Conclusions : There have been reported many acupuncture treatment studies of tic disorder in traditional chinese medicine. We believe that these studies could be applied to the clinical practices in Korea.

• Journal of Korean Academy of Nursing
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• v.35 no.6
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• pp.1036-1043
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• 2005

Purpose: The purpose of this study was to develop a vital signs e-book for undergraduate student nurses and evaluate the content, system and student satisfaction. Method: This study was done in three stages, the development of a vital signs e-book, implementation and evaluation. The subjects were 73 undergraduate student nurses in Y university. Result: Thirty one learning objectives were used to create the contents. A set of 5 chapters and 18 subsections were defined after validation from nurse educators. The e-book is available at http://123.134.207.23/ebook/vitalsigns. Analysis of the questionnaires showed a mean score for content, system and students satisfaction of $3.17\pm73,\;3.11\pm79,\;and\;2.96\pm.74$ respectively out of a possible 4 points. Conclusion: Nurse educators should provide quality and effective web-based courses that meet undergraduate student nurses' learning needs and they should incorporate web-based learning into traditional teaching to meet the demands of nursing education.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.21 no.2
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• pp.94-101
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• 2008

Objectives : To discuss the types of control groups in randomized controlled trials (RCTs) of herbal medicine, and to provide suggestions for improving the design of control group in future clinical trials. Methods : We reviewed the 8 articles about clinical trial design of Chinese herbal preparation which were published from 2005 through 2008. We selected those articles from CNKI(中國知識基礎施設工程(http://www.cnki.net)). Results : It is necessary to have control group in randomized controlled trials(RCTs) of Korean herbal preparation. But there are problems in the selection of appropriate control group drug. This paper lists several problems about the choice of control drug and puts forward some proposals and countermeasures. There are problems such as ethics and manufacturing matching placebo and positive control herbal drug. Conclusion : To improve the quality of control group design, we introduce standard drug plus placebo drug method and add-on research for placebo control group design, double dummy technique, using negative control drug or composite control drug for active control group design.

• Proceedings of the KSRS Conference
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• 2002.10a
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• pp.569-572
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• 2002

Terra MODIS is one of the few space-borne sensors currently capable of acquiring radiometric data over the range of view angles. Institute of Industrial Science, University of Tokyo, has been receiving Terra MODIS data at Tokyo since May 2001 and Asian Institute of Technology at Bangkok since May 2001. They can cover whole East Asia and is expected to monitor environmental changes regularly such as deforestation, forest fires, floods and typhoon. Over eight hundred scenes have been archived in the storage system and they occupy 2 TB of disk space so far. In this study, MODIS data processing system on WWW is developed including following functions: spectral subset (250m, 500m, 1000m channels), radiometric correction to radiance, spatial subset of geocoded data as a rectangular area with latitude-longitude grid system in HDF format, generation of a quick look file in JPEG format. Users will be notified just after all the process have finished via e-mail. Using this system enables us to process MODIS data on WWW with a few input parameters and download the processed data by FTP access. An easy to use interface is expected to promote the use of MODIS data. This system is available via the Internet on the following URL from September 1 2002, "http : //webmodis.iis.u-tokyo.ac.jp/".

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.65 no.4
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• pp.326-334
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• 2016

In this paper for developing and implementing the realtime HD level video streaming transmitter which is operated on the multi-platform in all network and client environment compared to the exist video live streaming transmitter. We design the realtime HD level video streaming transmitter supporting the multi-platform using the TMS320DM386 video processor of T.I company and then porting the Linux kernel 2.6.29 and implementing the RTSP(Real Time Streaming Protocol)/RTP(Real Time Transport Protocol), HLS(Http Live Streaming), RTMP(Real Time Messaging Protocol) that can support the multi-platform of video stream protocol of the received equipments (smart phone, tablet PC, notebook etc.). For proving the performance of developed video streaming transmitter, we make the testing environment for testing the performance of streaming transmitter using the notebook, iPad, android Phone, and then analysis the received video in the client displayer. In this paper, we suggest the developed the Realtime HD(High Definition) level Video Streaming transmitter performance data values higher than the exist products.

• The Journal of Korea Robotics Society
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• v.15 no.4
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• pp.404-412
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• 2020

Typically everyday human life tasks involve at least two people moving objects such as tables and beds, and the balancing of such object changes based on one person's action. However, many studies in previous work performed their tasks solely on robots without factoring human cooperation. Therefore, in this paper, we propose cooperative robot for table balancing using Q-learning that enables cooperative work between human and robot. The human's action is recognized in order to balance the table by the proposed robot whose camera takes the image of the table's state, and it performs the table-balancing action according to the recognized human action without high performance equipment. The classification of human action uses a deep learning technology, specifically AlexNet, and has an accuracy of 96.9% over 10-fold cross-validation. The experiment of Q-learning was carried out over 2,000 episodes with 200 trials. The overall results of the proposed Q-learning show that the Q function stably converged at this number of episodes. This stable convergence determined Q-learning policies for the robot actions. Video of the robotic cooperation with human over the table balancing task using the proposed Q-Learning can be found at http://ibot.knu.ac.kr/videocooperation.html.