• 제목/요약/키워드: HS model

검색결과 179건 처리시간 0.03초

경사도가 다른 수중 삼각형상구조물 주위의 유동특성 (Flow Characteristics around Underwater Triangular Structure with Different Inclination)

  • 최상범;조대환
    • 해양환경안전학회지
    • /
    • 제20권2호
    • /
    • pp.241-246
    • /
    • 2014
  • 본 연구에서는 수중 삼각형상구조물의 경사도와 레이놀즈 수 변화에 따른 구조물 주위의 유동특성을 분석하였다. 모델링한 삼각형상구조물 주위의 유동장은 회류수조에서 가시화실험과 입자영상유속계(PIV)를 이용하여 계측하였다. 실험결과 경사각이 $45^{\circ}$인 삼각형상구조물이 레이놀즈 수 $Re=2.9{\times}10^3$에서 구조물 높이의 2.7배까지 상승하는 속도성분이 나타났다. 레이놀즈 수가 일정할 때 경사각이 클수록 구조물 후방에 하강하는 속도성분이 크게 나타났고, y/hs=1.75이상의 영역에서는 경사각과 레이놀즈 수가 구조물 후방의 유동형태에 변화를 주지 않았다.

두충 추출물의 류마티스관절염 동물모델에 대한 개선 효과 (Improvement Effect of the Eucommia ulmoides Extracts on CIA-induced Rheumatoid Arthritis Animal Models)

  • 지중구
    • 한국응용과학기술학회지
    • /
    • 제39권1호
    • /
    • pp.18-26
    • /
    • 2022
  • 본 연구는 CIA에 의해 유발된 DBA/1 마우스를 통해 류마티스관절염 바이오마커에 대한 두충 추출물의 효과를 평가하였다. 평가를 위해 류마티스관절염 동물모델 제작 후 100 mg/kg/day로 4주간 경구 투여하고 혈청 바이오마커, 방사선, 구조적 매개변수 분석을 통해 치료 효과를 확인하였다. 음성대조군과 비교하여, 두충 추출물은 염증 및 면역글로불린 마커(TNF-α, IgG 및 hs-CRP)의 생성을 유의하게 감소시켰고, 백혈구의 단핵구 수를 유의적으로 감소시켰다. 또한, 두충 추출물은 관절 파괴를 효과적으로 보존하고 관절 변형을 줄였으며, 골 밀도의 증가와 유의적으로 골 염증을 감소시켰다. 이러한 결과는 두충 추출물이 류마티스관절염 증상을 개선하는 것을 나타낸다. 따라서, 두충 추출물은 류마티스관절염 관리를 위한 새로운 치료 옵션이 될 수 있음을 보여준다.

Estimated Risk of Radiation Induced Contra Lateral Breast Cancer Following Chest Wall Irradiation by Conformal Wedge Field and Forward Intensity Modulated Radiotherapy Technique for Post-Mastectomy Breast Cancer Patients

  • Athiyaman, Hemalatha;M, Athiyaman;Chougule, Arun;Kumar, HS
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제17권12호
    • /
    • pp.5107-5111
    • /
    • 2016
  • Background: Epidemiological studies have indicated an increasing incidence of radiation induced secondary cancer (SC) in breast cancer patients after radiotherapy (RT), most commonly in the contra-lateral breast (CLB). The present study was conducted to estimate the SC risk in the CLB following 3D conformal radiotherapy techniques (3DCRT) including wedge field and forward intensity modulated radiotherapy (fIMRT) based on the organ equivalent dose (OED). Material and Methods: RT plans treating the chest wall with conformal wedge field and fIMRT plans were created for 30 breast cancer patients. The risks of radiation induced cancer were estimated for the CLB using dose-response models: a linear model, a linear-plateau model and a bell-shaped model with full dose response accounting for fractionated RT on the basis of OED. Results: The plans were found to be ranked quite differently according to the choice of model; calculations based on a linear dose response model fIMRT predict statistically significant lower risk compared to the enhanced dynamic wedge (EDW) technique (p-0.0089) and a non-significant difference between fIMRT and physical wedge (PW) techniques (p-0.054). The widely used plateau dose response model based estimation showed significantly lower SC risk associated with fIMRT technique compared to both wedge field techniques (fIMRT vs EDW p-0.013, fIMRT vs PW p-0.04). The full dose response model showed a non-significant difference between all three techniques in the view of second CLB cancer. Finally the bell shaped model predicted interestingly that PW is associated with significantly higher risk compared to both fIMRT and EDW techniques (fIMRT vs PW p-0.0003, EDW vs PW p-0.0032). Conclusion: In conclusion, the SC risk estimations of the CLB revealed that there is a clear relation between risk associated with wedge field and fIMRT technique depending on the choice of model selected for risk comparison.

Batch and Flow-Through Column Studies for Cr(VI) Sorption to Activated Carbon Fiber

  • Lee, In;Park, Jeong-Ann;Kang, Jin-Kyu;Kim, Jae-Hyun;Son, Jeong-Woo;Yi, In-Geol;Kim, Song-Bae
    • Environmental Engineering Research
    • /
    • 제19권2호
    • /
    • pp.157-163
    • /
    • 2014
  • The adsorption of Cr(VI) from aqueous solutions to activated carbon fiber (ACF) was investigated using both batch and flow-through column experiments. The batch experiments (adsorbent dose, 10 g/L; initial Cr(VI) concentration, 5-500 mg/L) showed that the maximum adsorption capacity of Cr(VI) to ACF was determined to 20.54 mg/g. The adsorption of Cr(VI) to ACF was sensitive to solution pH, decreasing from 9.09 to 0.66 mg/g with increasing pH from 2.6 to 9.9; the adsorption capacity was the highest at the highly acidic solution pHs. Kinetic model analysis showed that the Elovich model was the most suitable for describing the kinetic data among three (pseudo-first-order, pseudo-second-order, and Elovich) models. From the nonlinear regression analysis, the Elovich model parameter values were determined to be ${\alpha}$ = 162.65 mg/g/h and ${\beta}$ = 2.10 g/mg. Equilibrium isotherm model analysis demonstrated that among three (Langmuir, Freundlich, Redlich-Peterson) models, both Freundlich and Redlich-Peterson models were suitable for describing the equilibrium data. In the model analysis, the Redlich-Peterson model fit was superimposed on the Freundlich fit. The Freundlich model parameter values were determined to be $K_F$ = 0.52 L/g and 1/n = 0.56. The flow-through column experiments showed that the adsorption capacities of ACF in the given experimental conditions (column length, 10 cm; inner diameter, 1.5 cm; flow rate, 0.5 and 1.0 mL/min; influent Cr(VI) concentration, 10 mg/L) were in the range of 2.35-4.20 mg/g. This study demonstrated that activated carbon fiber was effective for the removal of Cr(VI) from aqueous solutions.

폴리에틸렌 옥사이드-폴리메타크릴산 IPN 공중합체의 팽윤 및 약물 방출특성 (Swelling and Drug Release Characteristics of Poly (ethylene oxide)-Poly (methacrylic acid) Interpenetrating Networks)

  • 이승진
    • Journal of Pharmaceutical Investigation
    • /
    • 제21권3호
    • /
    • pp.149-153
    • /
    • 1991
  • Polyethylene oxide (PEO)-polymethacrylic acid (PMAA) interpenetrating polymer networks (IPN) were synthesized via radical polymerization of PMAA and simultaneous crosslinking of PEO using triisocyanate. The equilibrium swelling of PEO-PMAA IPN was determined at different pHs. The swelling of PEO-PMAA IPN, ranged from 20% to 90%, was more sensitive than that of homo polymer PMAA gel This is probably due to protonation and deprotonation of the PMAA network and interpolymer complex formation between PEO and PMAA. Several model drugs were loaded into the IPN matrices and the release mechanisms were investigated. The release of nonionizable drugs such as ftorafur and prednisolone was controlled by swelling of the matrices. However, he release of propranolol, positively charged drug, was more affected by the ionic interaction between the drug and PMAA newtork, and the interpolymer complexation.

  • PDF

입자의 분산안정성이 고형오구의 세척성에 미치는 영향(제1보) - Nonyl Phenol Polyoxyethylene Ether 용액 내에서 α-Fe2O3 입자의 분산안정성 - (Effect of Dispersion Stability of Particles on Detergency of Particulate Soil(Part 1) - The Dispersion Stability of α-Fe2O3 Particles in the Nonyl Phenol Polyoxyethylene Ether Solution -)

  • 강인숙
    • 한국의류산업학회지
    • /
    • 제4권1호
    • /
    • pp.86-91
    • /
    • 2002
  • To estimate dispersion stability of particles, suspending power and particle size were examined as functions of pHs, surfactants, electrolytes and ionic strengths using ${\alpha}-Fe_2O_3$ particle as the model of particulate soil. Suspending power and particle size were determined by UV-Vis spectrumeter and by light scattering using the polarization ratio method, respectively. The suspending power was relatively high with polyanion electrolytes and was low with neutral salts. The suspending power was biphasis, minimum pH 6~7, and the effect of surfactant on the suspending power was insignificant. Generally suspending power increased with decreasing the particle size governed aggregation of dispersed particles regardless of solution conditions. Hence the suspending power was inversely related to the particle size.

HSPDA 모형의 대규모 상수관망에의 적용 (Application of HSPDA Model to Large Water Network)

  • 백천우;전환돈;김중훈
    • 한국수자원학회:학술대회논문집
    • /
    • 한국수자원학회 2007년도 학술발표회 논문집
    • /
    • pp.2084-2088
    • /
    • 2007
  • 상수관망의 수리해석기법은 demand-driven analysis(DDA)와 pressure-driven analysis(PDA)로 구분할 수 있다. 관거 파괴나 용수수요 급증과 같이 용수공급시스템이 비정상상태인 경우 절점의 용수수요는 항상 만족한다는 가정을 사용하는 DDA의 경우 비현실적인 결과를 줄 수 있으며, 절점수요와 절점수두를 동시에 고려하는 PDA의 개념을 이용한 관망의 수리해석이 필요하다. PDA의 개념을 사용하여 개발된 기존의 많은 모형들은 복잡한 실제관망에는 적용이 불가능한 문제점들을 가지고 있으며, 본 연구에서는 화음탐색법(Harmony Search, HS) EPANET의 toolkit을 연계하여 개발된 HSPDA모형의 실제 대규모 상수관망에의 적용성을 검토하였다. 실제 대규모관망에의 적용성 향상을 위해 화음탐색법의 새로운 인자인 PIR를 제안하였으며 적용결과 새롭게 제안된 PIR은 HSPDA모형의 최적해탐색효율을 획기적으로 향상시켰으며, HSPDA모형을 이용한 실제 대규모관망의 비정상상태 수리모의가 가능한 것으로 판단된다.

  • PDF

곱셈꼴 잡음모형에서 비모수 확률 신호 검파기 (A nonparametric detector for random signals in a multiplicative noise model)

  • 배진수;박정순;김광순;송익호
    • 한국통신학회논문지
    • /
    • 제23권4호
    • /
    • pp.796-804
    • /
    • 1998
  • 이동통신 시스템을 분석할 때 중요한 여러길 전파를 모형화하는 데에는 곱셈꼴 잡음이 쓸모있다고 알려져 있다. 이 논문에서는 곱셈꼴 잡음에서 약한 신호의 비모수 검파를 생각한다. 관측값의 부호와 순위를 바탕으로 한국소최적 검파기는 어떤 잡음 분포에서도 신호의 세기가 약할 때 이를 검파하는 성능이 좋도록 한 것이다. 이 검파기는 곱셈꼴 잡음에서 확률 신호를 검파하는 국소최적 검파기와 비슷하다는 것을 보인다. 그리고, 이 비모수 검파기는 국소최적 검파기와 점근적으로 거의 같은 성능을 갖는다는 것을 보인다.

  • PDF

신경망이론을 이용한 소유역에서의 장기 유출 해석(수공) (Long Term Streamflow Forecasting in Small Watershed using Artificial Neural Network)

  • 강문성;박승우
    • 한국농공학회:학술대회논문집
    • /
    • 한국농공학회 2000년도 학술발표회 발표논문집
    • /
    • pp.384-389
    • /
    • 2000
  • A artificial neural network model was developed to analyze and forecast the flow fluctuation at small streams in the Balan watershed. Backpropagation neural networks were found to perform very well in forecasting daily streamflows. In order to deal with slow convergence and an appropriate structure, two algorithms were proposed for speeding up the convergence of the backpropagation method, and the Bayesian Information Criterion(BIC) was proposed for obtaining the optimal number of hidden nodes. From simulations using daily flows at the HS#3 watershed of the Balan Watershed Project, which is 412,5 ㏊ in size and relatively steep in landscape, it was found that those algorithms perform satisfactorily.

  • PDF

경량전철의 전원공급선에 의해 발생되는 자기장 차폐해석

  • 송명곤;오윤상;김동훈;주민석;노석균;이상진;박정도;정상기;정락교;조홍식
    • 한국철도학회:학술대회논문집
    • /
    • 한국철도학회 2003년도 추계학술대회 논문집(III)
    • /
    • pp.547-551
    • /
    • 2003
  • This paper presents the magnetic fields shielding properties of the light rail transit which are produced by the ripple-shaped currents in the power lines. To analyze these properties, the equivalent circuit model of the DC power supply system at the light rail transit system was induced by MATLAB-SIMULINK, and with the calculated results of the ripple-shaped currents, the magnetic fields shielding properties of the light rail transit were analyzed. The results are as follows. First The frequency of the ripple-shaped currents is 200[Hz] and its magnitude is 1.5[A]. Second the magnetic fields produced by the ripple-shaped currents of the DC power supply systems are well shielded by the aluminum made body of the light rail transit.

  • PDF