• Title/Summary/Keyword: HRL

Search Result 15, Processing Time 0.027 seconds

Ethanol Extract of Hippophae Rhamnoides L. Leaves Inhibits Adipogenesis through AMP-activated protein kinase (AMPK) Activation in 3T3-L1 Preadipocytes (비타민나무 잎 에탄올추출물의 AMPK 활성화를 통한 3T3-L1 지방전구세포의 adipogenesis 억제효과)

  • Jeong, Hyeon Ju;Park, Ju Hee;Kim, Myong-Jo
    • Korean Journal of Plant Resources
    • /
    • v.28 no.5
    • /
    • pp.582-590
    • /
    • 2015
  • In the present study, we investigated the effect of 70% EtOH extract from Hippophae Rhamnoides L. leaves (HRL) on the anti-obesity effect in 3T3-L1 cells. The effects of HRL on lipid accumulation in 3T3-L1 cells were examined using Oil Red O staining. In addition, we examined the gene expression levels by using RT-PCR and western blot. The results of this analysis showed that 100 ㎍/㎖ HRL significantly increased the inhibition of lipid accumulation by 82.25%; significantly decreased the mRNA expression of sterol regulatory element binding protein-1c (SREBP-1c), peroxisome proliferator-activated receptor γ (PPARγ), CCAAT/enhancer binding proteins α (C/EBPα), and fatty acid synthase (FAS) in 3T3-L1 cells as well as the stimulated protein expression of AMP-activated protein kinase (AMPK); and suppressed the expression level of PPARγ. These results suggest that HRL can prevent adipogenesis through activation of AMPKα and inhibition of adipogenesis transcription factors.

Isolation and Characterization of Rice OsHRL Gene Related to Bacterial Blight Resistance

  • Park, Sang-Ryeol;Moon, Seok-Jun;Shin, Dong-Jin;Kim, Min-Gab;Hwang, Duk-Ju;Bae, Shin-Chul;Kim, Jeong-Gu;Yi, Bu-Young;Byun, Myung-Ok
    • The Plant Pathology Journal
    • /
    • v.26 no.4
    • /
    • pp.417-420
    • /
    • 2010
  • The expression of HR-like lesion inducing gene of Oryza sativa (OsHRL) was slightly increased by Xanthomonas oryzae pv. oryzae (Xoo) infection. Transgenic rice plants over-expressing OsHRL gene were challenged with Xoo and the development of disease symptoms were examined to investigate the effect of OsHRL gene expression on plant defense responses. The over-expression of OsHRL increased disease resistance against Xoo compared with wild type plants.

Phenolic Compounds Contents of Rusty-Root Tolerance Ginseng Lines in 6-Year Old Root (6년생 적변내성 인삼계통의 Phenolic Compounds 함량 특성)

  • Lee, Sung-Sik
    • Journal of Ginseng Research
    • /
    • v.26 no.3
    • /
    • pp.165-169
    • /
    • 2002
  • Experiments were carried out to select marker for rusty tolerance ginseng root using high rusty degree lines(HRL) and low rusty degree lines (LRL) in ginseng plant. A strong positive correlation was detected between degree of rusty-root in 4-year-root and that in 6-year-root. The contents of phenolic compounds among samples were not different in stele and branch & fine roots. The contents of phenolic compounds of rusty-roots was higher than that of healthy-roots in cortex, but those of high 겨sty degree lines (HRL) were not different compared with low rusty degree lines (LRL) in cortex using same rusty-degree samples. These suggest that phenolic compounds in cortex tissue were not adequate as a marker to select rusty tolerance ginseng roots. The contents of phenolic compounds of rusty-roots were higher than that of healthy-roots in epidermis, and those of HRL were higher than LRL in epidermis using same rusty-degree samples. These suggested that the contents of phenolic compounds in epidermis tissue might be a potent marker to select rusty tolerance ginseng roots.

Comparative Study on the Educational Use of Home Robots for Children

  • Han, Jeong-Hye;Jo, Mi-Heon;Jones, Vicki;Jo, Jun-H.
    • Journal of Information Processing Systems
    • /
    • v.4 no.4
    • /
    • pp.159-168
    • /
    • 2008
  • Human-Robot Interaction (HRI), based on already well-researched Human-Computer Interaction (HCI), has been under vigorous scrutiny since recent developments in robot technology. Robots may be more successful in establishing common ground in project-based education or foreign language learning for children than in traditional media. Backed by its strong IT environment and advances in robot technology, Korea has developed the world's first available e-Learning home robot. This has demonstrated the potential for robots to be used as a new educational media - robot-learning, referred to as 'r-Learning'. Robot technology is expected to become more interactive and user-friendly than computers. Also, robots can exhibit various forms of communication such as gestures, motions and facial expressions. This study compared the effects of non-computer based (NCB) media (using a book with audiotape) and Web-Based Instruction (WBI), with the effects of Home Robot-Assisted Learning (HRL) for children. The robot gestured and spoke in English, and children could touch its monitor if it did not recognize their voice command. Compared to other learning programs, the HRL was superior in promoting and improving children's concentration, interest, and academic achievement. In addition, the children felt that a home robot was friendlier than other types of instructional media. The HRL group had longer concentration spans than the other groups, and the p-value demonstrated a significant difference in concentration among the groups. In regard to the children's interest in learning, the HRL group showed the highest level of interest, the NCB group and the WBI group came next in order. Also, academic achievement was the highest in the HRL group, followed by the WBI group and the NCB group respectively. However, a significant difference was also found in the children's academic achievement among the groups. These results suggest that home robots are more effective as regards children's learning concentration, learning interest and academic achievement than other types of instructional media (such as: books with audiotape and WBI) for English as a foreign language.

Mineral Nutrition Contents of Rusty-Root To1erance Ginseng Lines in 6-Year Old Root (6년생 적변내성 인삼계통의 무기성분함량 특성)

  • Lee, Sung-Sik;Lee, Kyoung-Hwan;Kim, Eun-Soo
    • Journal of Ginseng Research
    • /
    • v.26 no.3
    • /
    • pp.159-164
    • /
    • 2002
  • Experiments were carried out to select the rusty tolerance lines in 39 inbred lines of ginseng cultivated in field, among them, 7 lines showed low degree of rusty root while 7 lines showed high degree of rusty root. In order to select marker elements among mineral nutrients for rusty ginseng root, we combined 5 groups as follows : Ⅰ (healthy-root of low rusty degree lines vs. rusty-root of high rusty degree lines), II (healthy-root vs. rusty-root in low rusty degree lines), Ⅲ (healthy-root vs. rusty-root in high rusty degree lines), Ⅳ (low rusty degree lines vs. high rusty degree lines in rusty-root), Ⅴ (low rusty degree lines vs. high rusty degree lines in healthy-root), and analyzed mineral nutrition at different root parts. The contents of mineral nutritions in stele and cortex were not different between healthy lines and rusty lines, and between healthy roots and rusty roots, but that in branch and fine roots were not a tendency. The contents of Fe, Na and Al in epidermis were higher in rusty-root than healthy-root. Also, the contents of Fe and Al in epidermis of high rusty degree lines (HRL) were higher than those of low rusty degree lines (LRL) in healthy-roots and rusty-roots, and so we suggest Fe and Al as markers to select low rusty degree ginseng lines.

Trends on Human/Robot Interface Research (휴먼/로봇 인터페이스 연구동향 분석)

  • Im, Chang-Ju;Im, Chi-Hwan
    • Journal of the Ergonomics Society of Korea
    • /
    • v.21 no.2
    • /
    • pp.101-111
    • /
    • 2002
  • An intelligent robot, which has been developed recently, is no more a conventional robot widely known as an industrial robot. It is a computer system embedded in a machine and utilizes the machine as a medium not only for the communication between the human and the computer but also for the physical interaction among the human, the computer and their environment. Recent advances in computer technology have made it possible to create several of new types of human-computer interaction which are realized by utilizing intelligent machines. There is a continuing need for better understanding of how to design human/robot interface(HRI) to make for a more natural and efficient flow of information and feedback between robot systems and their users in both directions. In this paper, we explain the concept and the scope of HRI and review the current research trends of domestic and foreign HRL. The recommended research directions in the near future are also discussed based upon a comparative study of domestic and foreign HRI technology.

A DESIGN OF SMALL DATA UTILIZATION SYSTEM FORTHECOMS

  • Seo Seok-Bae;Ku In-Hoi;Kang Chi-Ho;Lirn Hyun-Su;Ahn Sang-IL
    • Proceedings of the KSRS Conference
    • /
    • 2005.10a
    • /
    • pp.268-271
    • /
    • 2005
  • COMS (Communication, Ocean, and Meteorological Satellite) will be launch at end of year 2008. For receiving of COMS LRlT, KARl (Korea Aerospace Research Institute) finished design and software realization of COMS SDUS (Small Data Utilization System). SDUS is a small station receiving LRlT data for distribute satellite image, weather information, and so on. For the future project, KARl preparing COMS MDUS (Mass Data Utilization System) that can receiving large size of data over than 2M BPS (Bit Per Seconds) data size.

  • PDF

Graphene field-effect transistor for radio-frequency applications : review

  • Moon, Jeong-Sun
    • Carbon letters
    • /
    • v.13 no.1
    • /
    • pp.17-22
    • /
    • 2012
  • Currently, graphene is a topic of very active research in fields from science to potential applications. For various radio-frequency (RF) circuit applications including low-noise amplifiers, the unique ambipolar nature of graphene field-effect transistors can be utilized for high-performance frequency multipliers, mixers and high-speed radiometers. Potential integration of graphene on Silicon substrates with complementary metal-oxide-semiconductor compatibility would also benefit future RF systems. The future success of the RF circuit applications depends on vertical and lateral scaling of graphene metal-oxide-semiconductor field-effect transistors to minimize parasitics and improve gate modulation efficiency in the channel. In this paper, we highlight recent progress in graphene materials, devices, and circuits for RF applications. For passive RF applications, we show its transparent electromagnetic shielding in Ku-band and transparent antenna, where its success depends on quality of materials. We also attempt to discuss future applications and challenges of graphene.

Effect of Radish Leaves Powder on the Gastrointestinal Function and Fecal Triglyceride, and Sterol Excretion in Rats Fed a Hypercholesterolemic Diet (무청분말이 콜레스테롤식이를 공급한 흰쥐의 장기능 및 분변 중 중성지질 및 Sterol 배설에 미치는 영향)

  • Jang, Hyun-Seo;Ahn, Jung-Mo;Ku, Kyung-Hyung;Rhee, Soon-Jae;Kang, Shin-Kwon;Choi, Jeong-Hwa
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.37 no.10
    • /
    • pp.1258-1263
    • /
    • 2008
  • The current study examined the effects of radish leaves powder on the excretion of fecal triglyceride, and sterol and hepatic UDP-glucuronyl transferase (UDPGT) activity in rats fed hypercholesterolemic diet. Male Sprague-Dawley rats weighing 100$\pm$10 g were randomly assigned to normal control group (N group), normal diet with 5% radish leaves powder supplemented group (NR) and hypercholesterolemic groups, which were sub-divided into radish leaves powder free diet group (HC) and 2.5% (HRL), 5% (HRM), and 10% (HRH) radish leaves powder supplemented groups. The experimental diets were fed ad libitum for 4 weeks. Fecal weights and water contents were significantly increased in all radish leaves powder supplemented groups (NR, HRL, HRM, and HRH) than that of N and HC groups. Fecal total lipid contents including fecal neutral and acidic sterols in radish leaves powder supplemented groups were higher than those of the HC group, and especially that of HRH group was the highest among all experimental groups. Hepatic UDPGT activity of HRH group was 38% higher than that of HC group. Excretions of fecal bile acid were increased 2.3 and 2.7 folds in HRM and HRH groups compared with that of HC group. And neutral sterol, coprostanol, and coprostanone contents of them were higher in radish leaves supplemented groups than in HC group. These results suggest that radish leaves may act as potential substitute for a dietary fiber capable of improving a gastrointestinal function and lipid metabolism.

Mapping of RFLP Markers Linked to Bacterial Blight Resistant Genes (Xa-1, Xa-3) in Rice (벼 흰잎마름병 저항성 유전자(Xa-1, Xa-3)연관 RFLP 마커 탐색)

  • 강현중;김현순;남정권;이영태;이승엽;김석동
    • KOREAN JOURNAL OF CROP SCIENCE
    • /
    • v.48 no.6
    • /
    • pp.419-423
    • /
    • 2003
  • Bacterial blight caused by Xantomonas oryzae pv. oryzae is one of the most serious diseases of rice especially in southern area of Korea. Three races, $\textrm{K}_1$, $\textrm{K}_2$ and $\textrm{K}_3$, are the most dominant species. lo improve rice breeding efficiency using marker assisted selection, some RFLP markers were surveyed for polymorphism between resistant and susceptible to $\textrm{K}_1$ and $\textrm{K}_3$. And, 127 doubled-haploid (DH) lines derived from Milyang121/HRl1650-1-4-2 and 131 DH lines derived from Milyang123/HR10624-AC5 were evaluated to bacterial blight ($\textrm{K}_1$ and $\textrm{K}_3$). Milyang121 and HR10624-AC5 have Xa-1, resistant to $\textrm{K}_1$ race, and Milyang123 has Xa-3, resistant to $\textrm{K}_1$ and $\textrm{K}_3$ race. Three markers, RZ590, RZ536 and RG303, showing polymorphism between parents and resistance gene, Xa-1 and Xa-3, were analysed in the two combinations of DH lines. The segregation pattern of resistant DH population of Milyang123/HR10624-AC5 to susceptible showed 3:1 and 1:1 in $\textrm{K}_1$ and $\textrm{K}_3$ race. In three RFLP markers, RZ590 was linked to Xa-1 on chromosome 4, and RZ536 and RG303 were linked to Xa-3 on chromosome 11. The map distance between Xa-1 and RZ590 was 3.1cM on chromosome 4, and Xa-3 and RZ536/RG303 were 7.6/16.0cM on chromosome 11, respectively. The results of RFLP mapping will be useful for the selection and pyramiding of bacterial blight resistant genes.