• Title/Summary/Keyword: HO

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Optical Properties of $TIGaSe_2$:Ho Single Crystals ($TIGaSe_2$:Ho 단결정의 광학적 특성)

  • 윤창선;노정숙;정상조;진문석;박홍이;송호준;김화택
    • Journal of the Korean Vacuum Society
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    • v.4 no.4
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    • pp.407-412
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    • 1995
  • TIGaSe2:Ho 결정에 대한 간접전이 에너지간격의 온도의존성은 각각 1차 상전이와 2차 상전이에 상당하는 100K와 108K에서 변칙특성을 보여주었다. TIGaSe2:Ho 결정에서 Ho3+이온에 긴인된 5I8$\longrightarrow$5I7과 5I8$\longrightarrow$5F5의 두 광학적 전이가 광흡수와 광전도도 스펙트라로부터 관측되었다. TIGaSe2와 TIGaSe2:Ho 결정의 열자극전류로부터 고유결함과 Ho 불순물에 관련된 양공 덫을 발견하였다.

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Pharmacognostical Studies on the 'JeonHo' (전호의 생약학적 연구)

  • Bae, Ji-Yeong;Ahn, Mi-Jeong;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.41 no.3
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    • pp.157-160
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    • 2010
  • Chinese crude drug 'JeonHo (前胡)' has been used mainly cough and dyspnea in respiratory infections. To clarify the botanical origin of 'JeonHo' in Korean market, the anatomical characterization of Anthriscus sylvestris, Angelica decursiva and Peucedanum praeruptorum were studied. As a result, it was clarified that 'JeonHo' in Korean market was the root of Peucedanum praeruptorum.

Anti-apoptotic Activity of Heme Oxygenase-1 Up-regulated by Etoposide in Human Retinal Pigment Epithelial Cells (Etoposide에 의한 인간 망막색소상피세포인 ARPE-19 세포의 아폽토시스 과정에서 Heme oxygenase-1의 항아폽토시스 기능에 대한 연구)

  • Lee, Sang-Kwon;Song, Ju-Dong;Kim, Kang-Mi;Kim, Jong-Min;Lee, Sang-Yull;Yoo, Young-Hyun;Park, Young-Chul
    • Journal of Life Science
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    • v.17 no.9 s.89
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    • pp.1204-1210
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    • 2007
  • The topoisomerase II inhibitor etoposide causes an accumulation of DNA double strand breaks within the nuclei of cells. In this study, we investigated the effect of etoposide on the cell growth and apoptosis of human RPE cells. Etoposide evoked a significant inhibition of cell growth, and also induced DNA fragmentation in ARPE-19 cells. In addition, etoposide significantly up-regulated the expression of heme oxygenase-1 (HO-1), which is a stress-responsive protein and is known to play a protective role against the oxidative injury. And, etoposide-induced HO-1 expression was affected by the ROS scavenger N-acetyl cysteine. We also used oligonucleotides interfering with HO-1 mRNA (siRNA) for the inhibition of HO-1 expression. Interestingly, knock-down of the HO-1 gene significantly increased the level of DNA fragmentation in etoposide-treated ARPE-19 cells. In conclusion, these results suggest that up-regulated HO-1 plays as an anti-apoptotic factor in the process of apoptosis of ARPE-19 cells stimulated by etoposide.

Severe Hemorrhage Induced Expressions of Ferritin and Heme Oxygenase-1 In Leukocytes (출혈로 인한 폐 염증세포에서의 ferritin과 heme oxygenase-1의 발현)

  • Kwon, Jung-Wan;Park, Yoon-Yub
    • Journal of Life Science
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    • v.19 no.7
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    • pp.878-885
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    • 2009
  • Serum ferritin levels are elevated in subjects with acute lung injury (ALI), and abnormalities in plasma and lung iron chemistry have also been demonstrated in ALI and acute respiratory distress syndrome (ARDS). Stress-inducible heme oxygenase-1 (HO-1), as well as ferritin, had shown anti-inflammatory actions. Biomarkers for early detection in patients who are likely to develop ARDS would give several therapeutic chances to the patients. In order to verify the predictability in severe hemorrhage-induced ALI in rats, we measured serum ferritin and HO-1 concentrations before and after hemorrhage. Severe hemorrhages significantly increased the number of leukocytes in bronchoalveolar lavage (BAL) fluid and lung tissue myeloperoxidase activity. Both serum ferritin and HO-1 levels increased following hemorrhage, but ferritin levels were elevated earlier than HO-1. In BAL cell immunohistochemical studies, ferritin and HO-1 expressions increased after hemorrhage and localized in the cytoplasm of leukocytes. These findings suggest that inflammatory leukocytes in BAL fluid can secrete ferritin and HO-1, and serum ferritin levels might be more valid factor in predicting ARDS than HO-1 levels in hemorrhage-induced ALI.

Distribution and Excretion of Radioactivity Following Intraportal Administration of $^{166}$ 7Ho-Chitosan Complex to Rats (흰쥐의 간문맥으로 투여한 $_{166}$ Holmium-chitosan의 분포와 배설)

  • BAEK, Min Sun;PARK, Kyung Bae;KIM, Dong Hyun
    • Biomolecules & Therapeutics
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    • v.5 no.3
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    • pp.233-238
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    • 1997
  • The distribution and excretion of radioactivity were examined after intraportal administration of sup 166/Ho-chitosan complex at a dose of 1 mcitg (10 mg chitosan/kg) to rats. Whole body macroautoluminographs showed that the radioactivity after an administration was concentrated in liver and perfused primarily to organs including kidney, spleen, and bone marrow, then to muscle and brain. Similar profiles were observed from 2 hr to 168 hr after the administration. The relative percentage of radioactivity in bone and spinal column increased with time, suggesting that free $^{166}$ Ho, released from chitosan complex deposited in the liver, selectively binds to these tissues. $^{166}$ Ho-chitosan complex administered intraportally was excreted less than 4% through urine (2.7$\pm$0.8%) and feces (0.65 $\pm$ 0.4%) up to seven days. These results demonstrate that the radio-activity of $_{166}$ Ho-chitusan complex when administered intraportally, mainly localizes in liver without affec-ting other tissues and organs. Considering the short half life of $^{166}$ Ho and the localization to the liver, $^{166}$ Ho-chitosan complex might be a useful agent in the treatment of hepatic carcinoma.

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In-situ Calibration of the Hydroperoxyl Radical Using an Immobilized TiO2 Photocatalyst in the Atmosphere

  • Kwon, Bum-Gun
    • Bulletin of the Korean Chemical Society
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    • v.29 no.4
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    • pp.785-789
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    • 2008
  • The present study is the first report of utilizing $TiO_2$ photocatalyst to analytically calibrate the hydroperoxyl radical ($HO_2\;^{\cdot}$). An in-situ calibration method of $HO_2\;^{\cdot}$ is proposed for air monitoring by using an 2-methyl-6-(pmethoxyphenyl)- 3,7-dihydroimidazo-[1,2-a]pyrazin-3-one (MCLA)-chemiluminescence (CL) technique. In this method, $HO_2\;^{\cdot}$($pK_a$ = 4.80) is produced by the ultraviolet (UV) photolysis of immobilized $TiO_2$ using a constant flow rate of air equilibrated water, in which $HO_2\;^{\cdot}$ is controlled by using various lengths of knotted tubing reactor (KTR). The principle of the proposed calibration is based on the experimentally determined halflife ($t_{1/2}$) of $HO_2\;^{\cdot}$ and its empirically observed pH-dependent rate constant, $k_{obs}$, at a given pH. The concentration of $HO_2\;^{\cdot}$/$O_2\;^{\cdot}$− is increased as pH increases. This pH dependence is due to the different disproportionative reactivities between $HO_2\;^{\cdot}$/$O_2\;^{\cdot}$− and $HO_2\;^{\cdot}$/$O_2\;^{\cdot}$−. Experimental results indicate the practical feasibility of the approach, producing very promising method.

Factors Affecting the Implementation of Environmental Accounting by Construction Companies Listed on the Ho Chi Minh Stock Exchange

  • NGUYEN, Thi Mai Huong;NGUYEN, Thi Kim Tuyen;NGUYEN, Thi Thao Vi
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.8
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    • pp.269-280
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    • 2020
  • The study investigates Environmental Accounting Information (EAI) as well as factors affecting the environmental accounting implementation by the construction firms listed on the Ho Chi Minh Stock Exchange (HOSE), Vietnam. After eliminating seven enterprises that lacked data, the authors selected a sample of 112 observations from 28 construction businesses listed on the Ho Chi Minh Stock Exchange in the period 2015-2018. This study uses research data extracted from the companies' annual reports. Then, the data are analyzed by Stata 13 software, including descriptive statistics, correlation coefficient analysis, regression analysis of table data using estimation methods (Pooled OLS, REM, FEM), and testing of model defects (heteroskedasticity test, multicollinearity test, autocorrelation test). The results show that construction companies listed on the Ho Chi Minh Stock Exchange have out factors affecting the environmental accounting implementation by these enterprises, including independent audit firm and listed time. While the independent auditor firm has a positive and significant impact, the listed time has a negative influence. In addition, our study has confirmed the role of institutional factors affecting the disclosure level of EAI on the implementation of environmental accounting by construction enterprises listed on the Ho Chi Minh Stock Exchange.

The Analysis of Lanthanides Using UV-VIS Spectrometer (UV-VIS 흡광광도법으로 란탄족원소들의 정량분석에 관한 연구)

  • Ji, Bong Il;Kim, Ha Seok;Ha, Yeong Gu
    • Journal of the Korean Chemical Society
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    • v.34 no.6
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    • pp.616-621
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    • 1990
  • The spectrophotometric methods for the determination of Nd, Pr, Sm, Eu, Ho, Er were developed, using the multicomponent method of absorption spectra cointerference. The absorption spectra of individual Nd, Pr, Sm, Eu, Ho, Er, mixture of Sm, Eu, Ho, Er in hydrochloric acid solutions were investigated, and also a band register which includes the molar absorptions for all trivalent Nd, Pr, Sm, Eu, Ho and Er absorption band maxima were measured. The spectrophotometric determination of Nd, Pr, Sm, Eu, Ho and Er were investigated using the analytically significant absorption bands at 444.2, 575.1, 401.7, 394.2, 416.6, and 379.7 nm, respectively.

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