• 한국미생물·생명공학회지
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• 제13권1호
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• pp.19-25
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• 1985

Saccharomyces cerevisiae HIS 5 유전자는 histidinol phosphate aminotransferase (EC: 2, 6, 1,9)를 code하는 아미노산 합성유전자이다. 이 유전자는 plasmid pSH 530에 cloning되어 E. coli와 Saccharomyces cerevisiae 숙주에서 promoter로서 전사하였다. HIS 5 유전자의 총염기 수는 736개이였고 5' 상류영역에는 긴 reading frame, directed repeat, 전사개시점, 그리고 Pribnow box염기배열이 있었다. 특히 HIS 5 유전자의 ATG 주변 염기배열은 -A-A-A-T-T-A-C-A-C-T-A-T-G-G-T-T-T-T-T-G-A-T-였으며 C block은 없었다.

• 대한가정학회지
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• 제18권1호
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• pp.83-95
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• 1980

The purpose of this study is to investigate the reasons of Object Attachment Occurrence in infant and the meanings of it in his early development. For this purpose, the following hypotheses were supposed. 1. Infant's object Attachment will be a substitutional for mother attachment when he has opportunities to his mother during his first years. 2. Infant's Object Attachment will not impede the infant's normal development. In order to test this hypotheses 28 mothers whose infants show or have shown this phenomenon and 28 mothers whose infants show or have shown this phenomenon and 28 mothers whose infants do not show this one were interviewed about their child rearing practice and attitude. They were selected by the random sampling method from 310 household wives living at a delux Apt. in Seoul. The results obtained in this study are as follow ; 1. The less opportunities infant has for 1) his mother's breast feeding 2) having physical contact with his mother 3) spending time with his mother 4) receiving prompt response from his mother to his crying, the more he is apt to show this phenomenon. And infant whose first main attachment figure is not his mother also shows the same apt. 2. There was no difference between two groups in intelligence and personality. So it can be concluded that infant's Object Attachment is a substitutional phenomenon for mother attachment in the mother during his first years, and it does not impede infant's normal development.

• 인문언어
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• 제1권1호
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• pp.159-183
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• 2001

This paper surveys the meaning of the pen name ′Yi Sang(李箱)′ in the light of the arbitariness of language and the relationship among names, observing in three ways how the images of ′Sang′ (Box) appear differently in his works. In Particular, we look into (1) the relationship between a box and its inner boxes, (2) the divisional relationship in the box, and (3) the relationship between the box and an outer box. In Yi Sang′s work, image (1) gives shape to the relationship between the writer himself and his ancestors who are responsible for his present existence. Image (2) gives shape to two internally divided Yi Sangs, and is symbolized as a mirror that reflects two selves. Image (3) gives shape to a relationship between himself in the closed world and other people and/or a bigger outside world. All these symbolic relationships are fully represented in his work "Nalgae" (The Wing)". What is interesting is that Yi Sang has already employed these box images in his earlier poetry "Geonchuk-muhan-yukmyeon-gaucho" (Infinite Architectural Hexagon). furthermore, by visualizing his name as a sqaure($\square$), he means to suggest the intentional image of his pen name as a ′box′.

• 한국실내디자인학회논문집
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• 제19권1호
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• pp.27-36
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• 2010

The purpose of this study is to define concept and characteristics of "Unphenomenon", the design concept conceived by Shiro Kuramata who is a world renowned Japanese interior designer and to explore how his ideas were materialized in his works. This study 1) examines his experience during his childhood reflected in his essay The scenery of the Unphenomenon' and training in Kuwazawa Design Institute that made Shiro Kuramata a true interior designer, and also considers how his design philosophy had been built up and realized under the unique social situation at the time. 2) defines the concept and characteristics of "Unphenomenon" as substance of his design philosophy by surveying remarks in his books and comments made by people around him in press interviews. 3) concludes his own design method and uniqueness by analyzing his works based on them. As a result, the study has founded that 1) transparency as recognitive realization of existence and non-existence: non-existence of physical property, connotation, ambiguity 2) expression of uncommonness by correcting and reinterpreting common prejudices: flotation, distortion of scale and shape 3) realization of insubstantiality by removing and replacing material and shape: replacement into light, removal of the structure, multiple layers of meaning.

• Weed & Turfgrass Science
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• 제5권4호
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• pp.187-190
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• 2016

4-HPPD저해 제초제에 의한 주요 벼품종의 약해반응과 약제반응에 관여하는 유전자(HIS1) 특성을 구명하기 위해 본시험을 수행하였다. Benzobicyclon 액상수화제 처리에 Japonica 품종인 상주벼에는 백화증상의 약해증상이 발생하지 않았으며, Japonica 품종임에도 불구하고 삼백벼에서는 기준량에서는 2-3, 배량에서는 3-4의 백화증상의 약해가 발생하였으며, 산들진미, 금영 품종에서는 3-4 및 4-5의 약해증상을 보였다. 또한 Indica 품종인 IR-8 품종에서는 기준량에서 3~5, 배량에서는 4~6의 가증 심한 약해증상을 보였다. 4-HPPD저해 제초제애 대해서 약제반응에 관여하는 HIS1 유전자 보유여부를 확인하기 위해 일반계 품종인 상주벼와, 삼백벼, 산들진미, 금영과 통일형 품종인 IR-8품종으로부터 저항성 표적유전자와 동일 HIS1 유전자를 분리하였다. 각 품종별 HIS1유전자를 PCR등을 통해 염기서열을 확인한 결과 HIS1 유전자는 생태형에 상관없이 시험한 5품종 모두에서 HIS1유전자를 보유하고 있는 것으로 확인되어, 본 유전자로 HPPD 약해 발생 유무를 검증할 수 없음이 확인되었다.

• 한국의사학회지
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• 제31권1호
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• pp.1-12
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• 2018

Gyoojoon Lee is a prominent figure of Confucianism and traditional medicine representing southern region of Korea during late $19^{th}$ and early $20^{th}$ century, but studies on his achievements were just started merely a decade ago. We would provide foundation for the further multidisciplinary study on his legacy. We reviewed his chronology, written works, interactions with intellectual figures, and current studies on his works to provide foundations for more thorough research on his legacy. We found he has wide spectrum of studies in medicine, confucianism, literature, humanism and philosophy during the late Chosun dynasty, Korean empire and Japanese colonization period. He wrote twenty five books in diverse fields and was found to have interactions with fifty seven figures with idea during his lifetime which need more detailed examination. Multidisciplinary studies on Gyoojoon Lee is guaranteed for the future in depth study on his works including Buyunglon (theory of supporting Yang).

• 한국실내디자인학회논문집
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• 제13권5호
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• pp.11-20
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• 2004

F. L. Wright was, from his early days, influenced by Japanese Culture and endeavored his original concept of orgonic orchitecture. In his 1st Golden Age, he devoted to establish an architectural concept of Organism which was proved by the theories of New Science and also had been universal in ancient Orient. Later, in his 2nd Golden Age, he tried to embody his unique concept in prairie houses and office buildings. The organic structure and spatial unit that actually applied to these works, were good examples of realization of the simplicity and continuity which he found out in Japanese culture. This paper is to study on the influence of Japanese culture on a course of Wright's embodying his organic architecture, and to study on a way of its realization in his works. To be concrete, main contents of the study are as follows; 1) the relationship between Wright's integrate perception and the orientalism 2) the influence of the traditional Japanese painting like woodblock prints and the aesthetic theory of the traditional Japanese pictorial art on Wright's design principles 3) the influence of Wright's experiences in Japan on his design principles 4) the influence of Wright's analysis of the traditional Japanese dwelling on his design principles 5) the course of Wright's embodying his organic architecture concept, and the way of its realization in his works.

• Genomics & Informatics
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• 제18권1호
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• pp.11.1-11.3
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• 2020

In genome-wide association studies, pathway-based analysis has been widely performed to enhance interpretation of single-nucleotide polymorphism association results. We proposed a novel method of hierarchical structural component model (HisCoM) for pathway analysis of common variants (HisCoM for pathway analysis of common variants [HisCoM-PCA]) which was used to identify pathways associated with traits. HisCoM-PCA is based on principal component analysis (PCA) for dimensional reduction of single nucleotide polymorphisms in each gene, and the HisCoM for pathway analysis. In this study, we developed a HisCoM-PCA software for the hierarchical pathway analysis of common variants. HisCoM-PCA software has several features. Various principle component scores selection criteria in PCA step can be specified by users who want to summarize common variants at each gene-level by different threshold values. In addition, multiple public pathway databases and customized pathway information can be used to perform pathway analysis. We expect that HisCoM-PCA software will be useful for users to perform powerful pathway analysis.

• 한국실내디자인학회논문집
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• 제22권1호
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• pp.97-104
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• 2013

This study aims at finding out the characteristics and influences of Libeskind's early drawing works through comparisons of each drawing. The importance of his experimental drawing works is not only their uniqueness but also relationship to creation and development of his architecture. Libeskind's musical and educational background had great impacts on forming his early drawings. A series of drawings including 'Micromegas', 'Chamberworks', and 'Theatrum Mundi' shows variety and experiments about reconstruction of three dimensional architectural fragments, abstractive line drawing and plane oriented painting. Libeskind himself cease to experiment drawing techniques but their characteristics still remain in his sketches, diagram and conceptual drawings. In spite of influences of undergraduate design studios, theoretical background of graduate studies, their experimental features are due to his continuous endeavor to make and develop his drawing skills and contents. As a result, his early drawings act as media and way to communicate and develop his concepts.

• Applied Biological Chemistry
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• 제28권1호
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• pp.36-47
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• 1985

Saccharomyces cerevisiae의 HIS5 유전자는 세균 vector인 pBR 322와 shuttle vector pSH 610에 clone되었고 lactose operon의 promoter로서 발현되었다. HIS5-lac Z fusion은 효모의 제III번 염색체에 integration하였으며 HIS5 유전자는 general amino acid control을 받고 있었다.