• Korean Chemical Engineering Research
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• v.57 no.4
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• pp.455-460
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• 2019

Hydrotreating catalysis refers to a various hydrogenation which saturate an unsaturated hydrocarbon, together with removing heteroatoms such as sulfur, nitrogen, oxygen, and trace metals from different petroleum streams in a refinery. Most refineries include at least three hydrotreating units for upgrading naphtha, middle distillates, gas oils, intermediate process streams, and/or residue. Among them, hydrotreating catalysis for residue are the core of the process, because of its complexity. This article reviews recent progress in tackling the issues found in the upgrading residues by hydrotreating, focusing on the chemistry of hydrodemetallization (HDM) and hydrodesulfurization (HDS). We also discuss the composition and functions of hydrotreating catalysts, and we highlight areas for further improvement.

• Journal of Haehwa Medicine
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• v.15 no.2
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• pp.121-134
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• 2006

This study saw the anti-allergy effect by the immunity regulation action of Yanghyelyoonbotang (YHYBT) consists 12 kinds of herbal medicine agents. Consequently, YHYBT controlled the amount of secretion of various infla- mmatory cytokines, chemokine, monocyte chemotactic protein and histamine from cells (HMC-1, THP-1, EoL-1) stimulated by PMA, A23187 or HDM. 1. YHYBT did not show cytotoxicity on cultured human fibroblast cells under 250 ${\mu}g/m\ell$ concentration. 2. YHYBT suppressed IL-8, TNF-$\alpha$, IL-6 mRNA expression in the HMC-1 cell stimulated with PMA and A23187. 3. YHYBT significantly suppressed IL-6 release in the THP-1 and EoL-1 cell stimulated with HDM. 4. YHYBT significantly suppressed histamine release in the HMC-1 cell stimulated with PMA and A23187 in a dose-dependent. 5. YHYBT significantly suppressed $\beta$-Hexosaminidase release in the HMC-1 cell stimulated with A23187 in a dose-dependent. 6. YHYBT suppressed NF-$\kappa$B gene expression in the RBL-2H3 cell stimulated with PMA in a dose-dependent. These results suggested that YHYBT has suppressive effects on allergic reaction and pro-inflammatory cytokines in various cell lines through the regulation of immune system. YHYBT has potential to use as an antiallergic agents.

• Journal of the Korean Society for Precision Engineering
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• v.21 no.8
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• pp.97-105
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• 2004

The vertical roller mill is the important machine grinding and mixing various crude materials in the manufacturing process of portland cement. Table liner is one of grinding elements of vertical roller mill and is subjected to the cyclic bending stress by rollers and the centrifugal force by rotation of table. It demands $4{\times}10^7$ expense of life but has $4{\times}10^6~-8{\times}10^6$ cycle. It fractures at the edge of grinding path of outside roller The repair expense fur it amounts to 30% of total maintenance of vertical roller mill. Therefore, this study shows the fracture mechanism of table liner of vertical roller mill using HDM and fatigue analysis

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.163-169
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• 2003

The vertical roller mill is the important machine grinding and mixing various crude materials in the manufacturing process of portland cement. Table liner is one of grinding elements of vertical roller mill and is subjected to the cyclic bending stress by rollers load and the centrifugal force by rotation of table. It demands $4{\times}10^7$ cycle but has $4{\times}10^6{\sim}8{\times}10^6$ cycle. It fractures at the edge of grinding path of outside roller. The repair expense for it amounts to 30% of total maintenance of vertical roller mill. Therefore, this study shows the fracture mechanism of table liner for vertical roller mill using HDM and fatigue analysis

• The Korean Journal of Physiology and Pharmacology
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• v.4 no.6
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• pp.497-506
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• 2000

In this work, GLUTs phosphorylations by a downstream effector of PI3-kinase, $PKC-{\zeta},$ were studied, and GLUT4 phosphorylation was compared with GLUT2 phosphorylation in relation to the translocation mechanism. Prior to phosphorylation experiment, $PKC-{\zeta}$ kinase activity was determined as $20.76{\pm}4.09$ pmoles Pi/min/25 ng enzymes. GLUT4 was phosphorylated by $PKC-{\zeta}$ and the phosphorylation was increased on the vesicles immunoadsorpted from LDM and on GLUT4 immunoprecipitated from GLUT4- contianing vesicles of adipocytes treated with insulin. However, GLUT2 in hepatocytes was neither phosphorylated by $PKC-{\zeta}$ nor changed in response to insulin treatment. It was confirmed by measuring the subcellular distribution of GLUT2 based on GLUT2 immunoblot density among the four membrane fractions before and after insulin treatment. Total GLUT2 distributions at PM, LYSO, HDM and LDM were $37.7{\pm}12.0%,\;42.4{\pm}12.1%,\;19.2{\pm}5.0%\;and\;0.7{\pm}1.2%$ in the absence of insulin. Total GLUT2 distribution in the presence of insulin was almost same as that in the absence of insulin. Present data with previous findings suggest that GLUT4 translocation may be attributed to GLUT4 phosphorylation by $PKC-{\zeta}$ but GLUT2 does not translocate because GLUT2 is not phosphorylated by the kinase. Therefore, GLUT phosphorylation may be required in GLUT translocation mechanism.

• Journal of Welding and Joining
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• v.8 no.4
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• pp.76-82
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• 1990

Lots of research works have been done to improve the accuracy of the hole drilling method to measure residual stress by many investigators. In this study, first, size effect of specimen was analyzed based on the solution of hole in a strip under tension. If the ratio of hole diameter tothe strip width is less than 0.2, the stress distribution around hold may be given from the solution of hole in an infinite plate. Second, the residual stress above $0.6{\sigma}_y$(yield stress) may be measured less than the actual stress by 10-15 percent. Third, eccentricity of hole relative to the rosette center effects on the accuracy of residual stress measurements by 10 percent. The error due to eccentricity of hole can be corrected by the iteration method or the direct method.

• International Journal of Korean Welding Society
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• v.4 no.1
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• pp.10-14
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• 2004

In this paper, a study on the residual stress of plate with longitudinal stiffeners is explained in terms of the welding sequences. In order to verify the results of numerical analysis, the hole drilling method (HDM) is performed, to measuring the residual stresses of the test plates in $CO_2$ Flux Cored Arc Welding (FCAW) under various welding conditions. The non-linear transient analysis technique for the numerical analysis in a large and complicate structure is considered. The residual stress of plate in consideration of the welding sequences and directions is evaluated by some numerical simulations and also by experiments. Comparison of numerical analysis results with experimental data shows the accuracy and validity of the proposed method.

• International Journal of Highway Engineering
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• v.4 no.4 s.14
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• pp.1-12
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• 2002

Pavement Management System has a special purpose that the rehabilitation strategy applied on pavement should be executable in view of technical and economical point after new pavement open to the traffic. To achieve that purpose, a reliable pavement performance prediction model should be embeded in the system. The object of this study is to develop a probabilistic pavement performance prediction model for evaluating asphalt pavements based on the Markov chain concept. In this paper, methodology of the Markov chain modeling principle is explained, and the application of this model to asphalt pavement is described. As the results, transition matrics for predicting asphalt pavement performance are obtained, and also performance life is estimated quantitatively by this system.

• Environmental Analysis Health and Toxicology
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• v.30
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• pp.8.1-8.8
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• 2015

Objectives Bedding in childcare centers (CCCs) can hold house dust mite (HDM) allergens. This study examined whether HDM allergen levels can be reduced through the distribution of an educational newsletter on bedding control to parents of CCC children in Korea. Methods All 38 CCCs were measured for Der 1 (sum of Der f 1 and Der p 1) concentrations on classroom floors and bedding before the intervention. Educational newsletters on children's bedding control were sent to 21 CCCs by mail, and teachers were asked to distribute the newsletters to the parents of the children (intervention group). The remaining 17 CCCs were not sent newsletters (control group). The measurement of Der 1 concentrations in 38 CCCs was repeated after the intervention. Dust samples were collected with a vacuum cleaner and analyzed using enzyme-linked immunosorbent assay methods. Results The Der 1 concentrations on the bedding were significantly higher than those on the floors in 38 CCCs at baseline (p < 0.05). Although changes of the Der 1 concentrations for the control group (n=17) were not significant, Der 1 concentrations for the intervention group (n=21) decreased significantly from 2077.9 ng/g dust to 963.5 ng/g dust on the floors and from 3683.9 ng/g dust to 610.4 ng/g dust on bedding (p < 0.05). Conclusions The distribution of educational newsletters on bedding control to parents may be an effective means of controlling HDMs in CCCs.

• Tuberculosis and Respiratory Diseases
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• v.47 no.6
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• pp.817-823
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• 1999

Background: The prevalence of allergic disease has increased substantially over the past decades. The reasons for these trends are complex but include increased environmental allergen exposure. Environmental control measures are of particular importance in the prevention and management of allergic disease. Thus, we purposed to evaluate the changes of causative allergens in allergic patients in Chonbuk provincial area that began industralized recently. Method: To evaluate the allergens epidemiologically, we performed skin prick tests and RAST in 201 allergic patients from February, 1984 to February, 1985 and 339 patients from February, 1997 to February, 1998. Results: The Following results were obtained. 1) Total sensitization rates did not change significantly(74.2% vs 75.8%, p=0.664). 2) Positive reaction rates to pollens were similar(35.8% vs 30.1%, p=0.17). 3) Positive rates to HDM(house dust mite) were decreased(66.1% vs 56.3%, p=0.02). 4) Positive rates to fungi and animal danders were decreased significantly(p<0.001). Conclusion : Environmental allergens associated with hygine in Chonbuk provincial areas such as HDM and fungi are decreased significantly during 13 years.