• 정보처리학회논문지A
• /
• 제9A권3호
• /
• pp.333-340
• /
• 2002

임베딩은 어떤 상호연결망 G를 다른 상호연결망 H에 사상시키는 것으로 연결망 G에서 개발된 알고리즘을 다른 연결망 H에서 시뮬레이션 할 수 있게 한다. 본 논문에서는 먼저 Hierarchical Cubic Network HCN(n, n) and Hierarchical Folded-hypercube Network HFN(n, n) 사이의 임베딩 방법을 제시한다. HCN(n, n)과 HFN(n, n)은 하이퍼큐브에서 제안된 성질을 가지면서 하이퍼큐브의 망비용 (분지수$\times$지름)을 개선한 상호연결망이다. HCN(n, n)은 HFN(n, n)에 연장율 3, 밀집율 2로 임베딩되고 평균연장율이 2 이하임을 보인다. HFN（n, n）은 HCN（n, n）에 연장율 0(n)에 임베딩 되지만, 평균연장율이 2 이하임을 보인다. 마지막으로 HCN（n, n）의 고장허용도에 대해 논하고, HCN（n, n）이 최대 고장 허용도(maximally fault tolerant)를 가짐을 보인다.

• Journal of Korean Neurosurgical Society
• /
• 제42권3호
• /
• pp.205-210
• /
• 2007

Objective : Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels mediate the hyperpolarization-activated currents (Ih) that participate in regulating neuronal membrane potential and contribute critically to pacemaker activity, promoting synchronization of neuronal networks. However, distinct regional and cellular localization of HCN channels in the brain have not been precisely defined. Aim of this study was to verify the precise cellular location of HCN1 channels in rat cerebellum to better understand the physiological role these channels play in synaptic transmission between CNS neurons. Methods : HCN1 expression in rat brain was analyzed using immunohistochemistry and electron-microscopic observations. Postsynaptic density-95 (PSD-95), otherwise known as locating and clustering protein, was also examined to clarify its role in the subcellular location of HCN1 channels. In addition, to presume the binding of HCN1 channels with PSD-95, putative binding motifs in these channels were investigated using software-searching method. Results : HCN1 channels were locally distributed at the presynaptic terminal of basket cell and exactly corresponded with the location of PSD-95. Moreover, nine putative SH3 domain of PSD-95 binding motifs were discovered in HCN1 channels from motif analysis. Conclusion : Distinct localization of HCN1 channels in rat cerebellum is possible, especially when analyzed in conjunction with the SH3 domain of PSD-95. Considering that HCN1 channels contribute to spontaneous rhythmic action potentials, it is suggested that HCN1 channels located at the presynaptic terminal of neurons may play an important role in synaptic plasticity.

• Animal cells and systems
• /
• 제11권2호
• /
• pp.199-204
• /
• 2007

HCN (hyperpolarization-activated cyclic nucleotide-gated) channels, whose gene family consists of four subunits (HCN1-4), mediate depolarizing cation currents and contribute to controlling neuronal excitability. In the present study, immunohistochemical and electrophysiological approaches were used to elucidate the role of HCN channels in the cerebellum. Immunohistochemical labeling for HCN1 and HCN2 channels revealed localized expression of both channels at pinceau, the specialized structure of presynaptic axon terminals of basket cells. To determine the functional role of the presynaptic HCN channels, spontaneous inhibitory postsynaptic currents (IPSCs) were recorded from Purkinje cells, the main synaptic targets of basket cells in the cerebellum. While activation of HCN channels by 8-bromo-cAMP increased amplitude of spontaneous IPSCs, blockade of the activated HCN channels by subsequent ZD7288 application reduced the amplitude of spontaneous IPSCs to the level far below the control. Our results imply that modulation of HCN1 and HCN2 channels in presynaptic terminals of basket cells regulates neurotransmitter release, thereby controlling the excitability of Purkinje cells.

• BMB Reports
• /
• 제45권11호
• /
• pp.635-640
• /
• 2012

To understand the effects of HCN as potential mediators in the pathogenesis of epilepsy that evoke long-term impaired excitability; the present study was designed to elucidate whether the alterations of HCN expression induced by status epilepticus (SE) is responsible for epileptogenesis. Although HCN1 immunoreactivity was observed in the hippocampus, its immunoreactivities were enhanced at 12 hrs following SE. Although, HCN1 immunoreactivities were reduced in all the hippocampi at 2 weeks, a re-increase in the expression at 2-3 months following SE was observed. In contrast to HCN1, HCN 4 expressions were un-changed, although HCN2 immunoreactive neurons exhibited some changes following SE. Taken together, our findings suggest that altered expressions of HCN1 following SE may be mainly involved in the imbalances of neurotransmissions to hippocampal circuits; thus, it is proposed that HCN1 may play an important role in the epileptogenic period as a compensatory response.

• 한국정보과학회:학술대회논문집
• /
• 한국정보과학회 2001년도 봄 학술발표논문집 Vol.28 No.1 (A)
• /
• pp.718-720
• /
• 2001

본 논문에서는 하이퍼큐브보다 망 비용이 개선된 상호연결망 HCN(n,n)의 임의의 두 노드간에 노드중복하지 않는 n+1개의 병렬경로를 구성하는 방법을 제시하고, 그 결과를 통하여 HCN(n,n)의 고장지름이 dia(HCN(n,n))+4 이하임을 보인다. 이러한 병렬경로는 노드간에 메시지를 전송하는 시간을 줄일 수 있으며, HCN(n,n)의 노드 몇 개가 고장이 발생해도 통신지연시간이 발생하지 않음을 의미한다.

• 정보처리학회논문지A
• /
• 제14A권6호
• /
• pp.327-332
• /
• 2007

본 논문에서는 $2^{2n-k}{\times}2^k$ 토러스 연결망과 상호연결망 HFN(n,n)과 HCN(n,n) 사이의 임베딩을 분석한다. 먼저, $2^{2n-k}{\times}2^k$ 토러스를 HFN(n,n)에 연장율 3과 밀집율 4로 임베딩 가능함을 보이며, 평균연장율이 2 이하임을 증명한다. 그리고 $2^{2n-k}{\times}2^k$ 토러스를 HCN(n,n)에 연장율 3으로 임베딩 가능함을 보이며, 평균 연장율이 2 이하임을 증명한다. 또한 HFN(n,n)과 HCN(n,n)이 $2^{2n-k}{\times}2^k$ 토러스에 임베딩하는 연장율이 O(n)임을 보인다. 이러한 결과는 토러스에서 개발된 여러 가지 알고리즘을 HCN(n,n)과 HFN(n,n)에서 효율적으로 이용할 수 있음을 의미한다.

• 한국정보통신학회논문지
• /
• 제18권6호
• /
• pp.1361-1368
• /
• 2014

본 연구에서는 하이퍼큐브의 망비용을 개선한 계층적 상호연결망 HFCube(n,n), HCN(n,n), HFN(n,n)의 임베딩을 분석한다. 연구 결과는 다음과 같다. 하이퍼큐브 $Q_{2n}$는 HFCube(n,n)에 연장율 3, 밀집율 2에 임베딩 가능하다. HFCube(n,n)은 HFN(n,n)과 HCN(n,n)을 부그래프(subgraph)로 갖고 있다. HFCube(n,n)은 HFN(n,n)에 연장율 3에 사상 가능하고, HFCube(n,n)을 HCN(n,n)으로 임베딩 하는 연장율 비용은 O(n)임을 보인다. 이러한 결과는 각 연결망의 여러 가지 유용한 성질들을 분석하는데 도움이 될 것이다.

• 천문학논총
• /
• 제13권1호
• /
• pp.129-134
• /
• 1998

Observations of the J=1-0 transition line of HCN were made at the center of Comet C/1995 O1 (Hale-Bopp) from November, 1996 to April, 1997 with the 14-m radio telescope at the TRAO (Taeduk Radio Astronomical Observatory). From the obtained data, an HCN production rate at each observed date was derived. The rapid variation of the HCN production rate near the perihelion was detected, and it is thought to be caused by jet(s) from the nucleus. The correlation between the visual magnitude and the HCN production rate is found to be $Q_{HCN}=27.03-0.11(m_v-5log{\Delta})$.

• 천문학회보
• /
• 제35권1호
• /
• pp.60.2-60.2
• /
• 2010

We have studied the abundance ratio of HNC and HCN toward the Red MSX Sources (RMS) using HCN (J=1-0), HNC (J=1-0), $H^{13}CN$ (J=1-0), $HN^{13}C$ (J=1-0),and $N_2H^+$ (J=1-0) lines observed with the Mopra 22 m radio telescope. The RMS are massive young stellar objects identified by the MSX satellite data combined with the 2MASS data. HCN and HNC (a geometrical isomer of HCN) are among the most basic interstellar molecules. According to our analysis, the column density of HCN is found to be correlated with that of HNC. Additionally, the [HNC]/[HCN] abundance ratio is sensitive to the core temperature because HNC is depleted in high temperature regions. This result is consistent with the previous results seen in low mass starless or protostellar cores.

• 한국정보통신학회:학술대회논문집
• /
• 한국해양정보통신학회 2000년도 추계종합학술대회
• /
• pp.412-418
• /
• 2000

본 논문에서는 HCN(n,n)이 Hamiltonian Cycles을 갖는다는 것을 증명하고, HCN(n,n)과 HFN(n,n) 사이의 임베딩을 분석하고, HFN(n,n)과 2n-hypercube사이의 임베딩을 분석한다. HCN(n,n)을 HFN(n,n)에 연장율 3에 임베딩 가능함을 증명하고, HFN(n,n)을 HCN(n,n)에 임베딩하는 비용이 O(n)임을 증명하며, HFN(n,n)을 2n-hypercube애 연장율 3에 임베딩 가능함을 증명하고, 2n-hypercube을 HFN(n,n)에 임베딩하는 비용이 O(n)임을 증명한다