• Tuberculosis and Respiratory Diseases
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• 제84권4호
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• pp.282-290
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• 2021

Background: Radial probe endobronchial ultrasound-guided transbronchial lung biopsy (RP-EBUS-TBLB) has improved the diagnostic yield of bronchoscopic biopsy of peripheral pulmonary lesions (PPLs). The diagnostic yield and complications of RP-EBUS-TBLB for PPLs vary depending on the technique, such as using a guide sheath (GS) or fluoroscopy. In this study, we investigated the utility of RP-EBUS-TBLB using a GS without fluoroscopy for diagnosing PPLs. Methods: We retrospectively reviewed data from 607 patients who underwent RP-EBUS of PPLs from January 2019 to July 2020. TBLB was performed using RP-EBUS with a GS without fluoroscopy. The diagnostic yield and complications were assessed. Multivariable logistic regression analyses were used to identify factors affecting the diagnostic yields. Results: The overall diagnostic accuracy was 76.1% (462/607). In multivariable analyses, the size of the lesion (≥20 mm; odds ratio [OR], 2.06; 95% confidence interval [CI], 1.27-3.33; p=0.003), positive bronchus sign in chest computed tomography (OR, 2.30; 95% CI, 1.40-3.78; p=0.001), a solid lesion (OR, 2.40; 95% CI, 1.31-4.41; p=0.005), and an EBUS image with the probe within the lesion (OR, 6.98; 95% CI, 4.38-11.12; p<0.001) were associated with diagnostic success. Pneumothorax occurred in 2.0% (12/607) of cases and chest tube insertion was required in 0.5% (3/607) of patients. Conclusion: RP-EBUS-TBLB using a GS without fluoroscopy is a highly accurate diagnostic method in diagnosing PPLs that does not involve radiation exposure and has acceptable complication rates.

• 한국추진공학회지
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• 제15권2호
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• pp.62-67
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• 2011

현재의 많은 유도무기들은 발사관에 장착되어 이동된다. 발사관이란 유도탄등이 외부환경에 노출되지 않도록 유도탄을 보호하고, 발사시 유도탄을 가이드 하는 역할을 한다. 발사관에 장착되어 있는 유도탄은 발사관에 견고하게 장착되어 이동되어야 하며, 작전시 원하는 시간에 분리되어야 한다. 이를 위하여 구조적인 안전성이 크고, 분리 응답이 빠른 파이로 장치인 폭발볼트가 많이 사용된다. 폭발볼트는 화약의 폭발력에 의해 볼트몸체가 절개됨으로써 볼트에 의해 결합되고 있던 부분이 분리되는데, 폭발 볼트는 분리시 파편, 화염 및 pyro-shock이라는 큰 진동과 충격을 수반하므로 정밀한 유도무기에는 사용이 제한된다. 이와 같은 문제점을 해결하기 위하여 압력카트리지에서 발생하는 압력을 분리력으로 사용하여, 충격이 작고, 분리파편이 발생하지 않는 분리장치인 볼타입 분리볼트를 개발하였다. 본 연구에서는 볼타입 볼트의 분리현상을 분석하고, 볼타입 분리볼트의 분리 안전율을 정량적으로 제시하였다.

• 대한세포병리학회지
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• 제9권1호
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• pp.55-61
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• 1998

To compare the diagnostic yields and complication rates of transthoracic fine needle aspiration cytology(FNAC) and gun biopsy in the diagnosis of pulmonary mass, a retrospective review was performed in 125 cases. Under the fluoroscopic guide, FNAC was performed by 20G Chiba needle in 91 cases, core biopsy was done by 18.5 G vaccum needle attached with automated biopsy gun in 74 cases and both procedures were done together in 37 cases. Overall sensitivity was 88.4% in FNAC and 87.5% in gun biopsy. For malignant pulmonary tumors, correct type correlation with final diagnosis was obtained in 33(76.7%) out of 43 cases by FNAC and 30(75.0%) out of 40 cases by gun biopsy. For benign pulmonary lesions, there were correct type correlation in 14(35.0%) out of 40 cases by FNAC and 14(53.8%) out of 26 cases by gun biopsy. The complication was pneumothorax and hemoptysis. Pneumothorax occured in 11.1% of FNAC, 10.9% of gun biopsy and 10.9% of both technique, among which chest tube drainages were necessary in one patient by gun biopsy and in three patients by both technique. Although no significant difference of diagnositc accuracy and complication rate was found between FNAC and gun biopsy, gun biopsy was more helpful in the diagnosis of pulmonary benign lesions than FNAC.

• 한국진공학회지
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• 제16권1호
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• pp.7-14
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• 2007

수평형 중성자 반사율 측정 장치는, 나노 박막의 두께와 구성성분, 표면의 거칠기 등 그 구조와 더불어 나노 박막의 동역학적인 거동을 연구하는데 긴요한 측정 장치이다. 특히, 수평형이기 때문에 액체시료의 자유표면을 유지하며 표면을 분석하는 것이 가능하다. 30 MW의 하나로의 열중성자원에 적합하도록 최적화하기 위하여, 몬테카를로 수치해석 방법을 적용한 McStas를 사용하여 장치의 각 부분에서의 중성자의 빔을 추적 계산하였고 그 결과의 해석과 그에 따른 설계변수결정을 기술하였다. 최적화 상태에서 단색파장이 ${\lambda}=2.5{\AA}$ 이고 $q<0.126{\AA}^{-1}$ 그리고 시료위치에서 $10^4n/cm^2/s$ 이상의 중성자빔의 세기를 얻었다. 본 장치가 설치 완료되면 국내에서 나노박막의 구조를 연구하는데 크게 기여할 것이다.

• 대한기계학회논문집A
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• 제35권4호
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• pp.417-424
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• 2011

핵연료집합체는 상단고정체, 하단고정체, 지지격자체, 제어관/계측관과 핵연료봉의 5 가지 주요 구성품으로 이루어져 있다. 여기서 상/하단고정체는 다른 구성품과 달리 ASME, Section III, Division 1 - Subsection NB 의 운전조건 A, B 에서의 stress intensity limits 를 만족하여야 한다. 이중냉각 핵연료집합체는 집합체당 출력을 증가시키기 위해서 기존의 가압경수로용 핵연료집합체에서 핵연료봉의 배열과 위치를 변화시켰는데 이로 인하여 핵연료봉 내/외부유로로 냉각수가 잘 흐를 수 있도록 상/하단고정체의 유로판의 형상을 수정하여야 한다. 본 논문에서는 설계하중조건에 대하여 수정된 상단고정체 유로판의 건전성평가를 위해 수행한 응력선형화과정을 자세히 설명하고 평가결과에 대하여 기술하였다.

• 한국유체기계학회 논문집
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• 제18권3호
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• pp.46-52
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• 2015

Pump-turbine system is widely used by the hydropower industry for stabilizing the electrical grid in the vast growing economy of most developed countries. This study only investigates the Fluid-structure Interaction (FSI) analysis of the pump-turbine system at various operating conditions. The FSI analysis can show how reliable each component of the system is by providing the engineer with a better understanding of high stress and deformation points, which could reduce the lifespan of the pump-turbine. Pump-turbine components are categorized in two parts, pressurized static parts and movable stressed parts. The fixed parts include the spiral casing, top and bottom cover, stay vane and draft tube. The movable parts include guide vanes and impeller blades. Fine hexahedral numerical grids were used for CFD calculation and fine tetrahedral grids were used for structural analysis with imported load solution mapping greater than 90 %. The maximum equivalent stress are much smaller than the material yield stress, and the maximum equivalent stress showed an increasing tendency with the varying of operating conditions from partial to excessive at both modes. In addition, the total deformation of all the operating conditions showed a small magnitude, which have quite small influence on the structural stability. It can be conjectured that this system can be safely implemented.

• The Korean Journal of Physiology and Pharmacology
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• 제2권3호
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• pp.307-312
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• 1998

This study was performed to investigate the mechanism of central analgesic effects of antidepressants. Thirty four male rats were anesthetized with pentobarbital sodium (40 mg/kg, ip). A stainless steel guide cannula and a PE tube (PE10) were implanted into the lateral ventricle and cisterna magna area. Stimulating and recording electrodes were implanted into the incisor pulp and anterior digastric muscle. Electrodes were led subcutaneously to the miniature cranial connector sealed on the top of the skull with acrylic resin. The jaw opening reflex was used in freely moving rats, and antidepressants were administered intracisternally in order to eliminate the effects of anesthetic agents on the pain assessment and evaluate the importance of the central action site of antidepressants. After 48 hours of recovery from surgery, digastric electromyogram (dEMG) of freely moving rats was recorded. Electrical shocks (200 ${\mu}sec$ duration, 0.5-2 mA intensity) were delivered at 0.5 Hz to the dental pulp every 2 minute. Intracisternal administration of $15\;{\mu}g$ imipramine suppressed dEMG elicited by noxious electrical stimulation in the tooth pulp to $76{\pm}6%$ control. Intracisternal administration of $30\;{\mu}g$ desipramine, nortriptyline, or imipramine suppressed dEMG remarkably to $48{\pm}2,\;27{\pm}8,\;or\;25{\pm}5%$ of the control, respectively. Naloxone, methysergide, and phentolamine blocked the suppression of dEMG produced by intracisternal antidepressants from $23{\pm}2\;to\;69{\pm}4%,\;from\;32{\pm}5\;to\;80{\pm}9%,\;and\;from\;24{\pm}6\;to\;77{\pm}5%$ of the control, respectively. These results indicate that antidepressants produce antinociception through central mechanisms in the orofacial area. Antinociception of intracisternal antidepressants seems to be mediated by an augmentation of descending pain inhibitory influences on nociceptive pathways.

• Restorative Dentistry and Endodontics
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• 제28권6호
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• pp.485-490
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• 2003

Complete understanding of the exterior and interior structure of the tooth would be prerequisite to the successful clinical results, especially in the restorative and endodontic treatment. Although three-dimensional reconstruction method using x-ray microtomography could not be used in clinical cases, it may be the best way to reconstruct the morphologic characteristics of the tooth structure in detail without destructing the tooth itself. This study was done to three dimensionally reconstruct every teeth in the arch in order to increase the understanding about the endodontic treatment and to promote the effective restorative treatment by upgrading the knowledge of the tooth morphology. After placing tooth between the microfocus x-ray tube and the image intensifier to obtain two-dimensional images of each level. scanning was done under the condition of 80 keV, $100{\;}\mu\textrm{m}$, 16.8 magnification with the spot size of $8{\;}\mu\textrm{m}$. Cross-section pixel size of $16.28{\;}\mu\textrm{m}$ and 48.83 cross-section to cross-section distance were also used. From the results of this study, precise three dimensional reconstructed images of every teeth could be obtained. Furthermore, it was possible to see image that showed interested area only, for example. enamel portion only, pulp and dentin area without enamel structure, pulp only, combination image of enamel and pulp, etc. It was also possible to see transparent image without some part of tooth structure. This image might be used as a guide when restoring and preparing the full and partial crown by showing the positional and morphological relationship between the pulp and the outer tooth structure. Another profit may be related with the fact that it would promote the understanding of the interior structure by making observation of the auto-rotating image of AVI file from the various direction possible.

• Nuclear Engineering and Technology
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• 제55권9호
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• pp.3133-3139
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• 2023

Neutron imaging technology as a means of non-destructive detection of materials is complementary to X-ray imaging. Silicon photomultiplier (SiPM), a new type of optical readout device, has overcome some shortcomings of traditional photomultiplier tube (PMT), such as high-power consumption, large volume, high price, uneven gain response, and inability to work in strong magnetic fields. Its application in the field of neutron detection will be an irresistible general trend. In this paper, a thermal neutron imaging detector based on ⁶LiF/ZnS scintillation screen and SiPM array readout was developed. The design of the detector geometry was optimized by geant4 Monte Carlo simulation software. The optimized detector was evaluated with a step wedge sample. The results show that the detector prototype with a 48 mm × 48 mm sensitive area can achieve about 38% detection efficiency and 0.26 mm position resolution when using a 300 ㎛ thick ⁶LiF/ZnS scintillation screen and a 2 mm thick Bk7 optical guide coupled with SiPM array, and has good neutron imaging capability. It provides effective data support for developing high-performance imaging detectors applied to the China Spallation Neutron Source (CSNS).

• 한국군사과학기술학회지
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• 제26권3호
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• pp.227-233
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• 2023

In this paper, to substitute the existing TWTA(Travailing Wave Tube Amplifier) component in small radar system, we developed the Ku band SSPA(Solid-State Power Amplifier) based on the fabrication of power MMIC (Monolithic Microwave Integrated Circuit) chips. For the development of the 500 W SSPA, the 40 W-grade power MMIC was designed by ADS(Advanced Design System) at Keysight company with UMS GH015 library, and was processed by UMS foundry service. And 70 W main power modules were achieved the 2-way T-junction combiner method by using the 40 W-grade power MMICs. Finally, the 500 W SSPA was fabricated by the wave guide type power divider between the drive power amplifier and power modules, and power combiner with same type between power modules and output port. The electrical properties of this SSPA had 504 W output power, -58.11 dBc spurious, 1.74 °/us phase variation, and -143 dBm/Hz noise level.