• Title/Summary/Keyword: Growth promoters

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Novel zinc sources as antimicrobial growth promoters for monogastric animals: a review

  • Lei, Xin Jian;Liu, Zhang Zhuang;Park, Jae Hong;Kim, In Ho
    • Journal of Animal Science and Technology
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    • v.64 no.2
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    • pp.187-196
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    • 2022
  • The essentiality of zinc for animals has been recognized over 80 years. Zinc is an essential trace element that is a component of many enzymes and is associated with the various hormones. Apart from the nutritional function, zinc has antimicrobial property and often be supplemented in diets in the quantities greater than which is required to meet the nutritional requirement, especially for weaning pigs. This review will focus on the application of pharmacological zinc and its mechanisms which may be responsible for the effects of zinc on performance and health of monogastric animals. Various novel sources of zinc in non-ruminant animal production will also be discussed. These should assist in more precisely formulating feed to maximize the production performance and to maintain the health condition of monogastric animals.

Nutrition and feed approach according to pig physiology

  • Park, Sangwoo;Kim, Byeonghyeon;Kim, Younghoon;Kim, Sheena;Jang, Kibeom;Kim, Younghwa;Park, Juncheol;Song, Minho;Oh, Sangnam
    • Korean Journal of Agricultural Science
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    • v.43 no.5
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    • pp.750-760
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    • 2016
  • The use of antibiotics in Korean swine production has been changing to a restricted use of in-feed antibiotics. These antibiotics, which are also growth promoters, are powerful for disease control. Due to this issue, the swine industry is consistently looking for any kind of alternatives to antibiotics such as new feed ingredients, feed additives, feed formulation practices, or feeding methods to improve pig health and performance. In general, dietary factors provide bioavailable nutrients and/or affect physiological activity to modify the physiological condition, immune system, or microbial population of pigs to improve their performance and health. Thus, it is suggested that dietary factors may be important components in the growth and health management of pigs. Using an alternative grain feed such as rice, barley, and oats, low protein diets or low-high energy diets can be used as solutions to manage the effect of stress factors that cause growth and health problems at specific time points during the stages of pig production. Several studies support that these alternative feeds and dietary factors may improve pig growth and health by changes in intestinal conditions, immunity, or other physiological conditions compared with typical feed ingredients and diet management in pig production. Therefore, feed ingredients, low protein levels, and different energy contents in swine diets were reviewed to better understand how these dietary factors can contribute to improved pig performance and health under different physiological conditions.

Dietary addition of a standardized extract of turmeric (TurmaFEEDTM) improves growth performance and carcass quality of broilers

  • Johannah, NM;Ashil, Joseph;Balu, Maliakel;Krishnakumar, IM
    • Journal of Animal Science and Technology
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    • v.60 no.5
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    • pp.8.1-8.9
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    • 2018
  • Background: Indiscriminate use of antibiotics in livestock and poultry farming has caused emergence of new pathogenic strains. The situation has warrented the development of safe and alternative growth promoters and immunity enhancers in livestock. Herbal additives in animal and bird feed is a centuries-old practice. Thus, the present study investigated the efficacy of a standardized formulation of lipophilic turmeric extract containing curcumin and turmerones, (TF-36), as a natural growth promoter poultry feed additive. Methods: The study was designed on 180 one-day old chicks, assigned into three groups. Control group ($T_0$) kept on basal diet and supplemented groups $T_{0.5}$ and $T_1$ fed with 0.5% and 1% TF-36 fortified basal diet for 42 days. Each dietary group consisted of six replicates of ten birds. Body weight, food intake, food conversion ratio, skin colour, blood biochemical analysis and antioxidant status of serum were investigated. Results: Body weight improved significantly in $T_1$ with a 10% decrease in FCR as compared to the control. TF-36 supplementation in $T_1$ enhanced the antioxidant enzyme activity significantly (p < 0.05) with a decrease (p < 0.05) in lipid peroxidation. It also caused a slight yellow skin pigmentation without any change in meat color, indicating the bioavailability of curcumin from TF-36. However, no significant change in the concentration of serum creatinine, total protein and liver enzyme activities were observed, indicating the safety. Conclusion: In summary, we concluded that TF-36 can be a natural feed additive to improve growth performance in poultry, probably due to the better antioxidant activity and antimicrobial effects contributed by the better bioavailability of curcuminoids and turmerones. Besides, curcuminoids and turmerones were also known to be gastroprotective and anti-inflammatory agents.

Recent Progress in Understanding Host Mucosal Response to Avian Coccidiosis and Development of Alternative Strategies to Mitigate the Use of Antibiotics in Poultry Production

  • Lillehoj, Hyun-Soon;Lee, Sung-Hyen;Jang, Seung-Ik;Kim, Duk-Kyung;Lee, Kyung-Woo
    • Korean Journal of Poultry Science
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    • v.38 no.4
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    • pp.275-284
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    • 2011
  • As the world population grows and developing countries become more affluent, the global consumption of meat will increase by more than 50% within the next 10 years. Confronting the increased demand for poultry food products are emerging field diseases, increasing regulatory bans of antimicrobial growth promoters, high-density growth conditions, and waste management. Although biotechnology offers solutions to some of these challenges, basic studies are needed to better understand the complex interaction between the intestinal microbiome, host immunity and the environment. This presentation will focus on emerging strategies to enhance gut immunity and to decrease economic losses due to poultry diseases. This presentation will highlight recent developments in coccidiosis research and provide information on host immunity, immunomodulation, and the latest advances in dietary and nutritional approaches against coccidiosis. Such information will magnify our understanding of host-parasite biology, mucosal immunology, and design of future nutritional interventions and vaccination strategies for coccidiosis.

Effect of Alkali Promoter in CO Hydrogenation Using Co/NaY Catalyst (Co/NaY 촉매를 이용한 CO 수소화 반응에 있어서 알칼리 첨가제의효과)

  • Myong-Mo Sung;Min-Young Youn;Yunsoo Kim;Hang Nam Paik
    • Journal of the Korean Chemical Society
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    • v.32 no.5
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    • pp.501-506
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    • 1988
  • The effects of alkali promoters on the activity and selectivity of Co/NaY catalyst have been investigated. The catalysts were prepared by impregnating NaY with aqueous solutions of alkali compounds and a benzene solution of $Co_2(CO)_8$. Hydrocarbon synthesis was studied in a flow reactor under the reaction conditions : temperature = 200∼250$^{\circ}C$, space velocity = 120∼$160hr^{-1}$, pressure = 1 atm, $H_2$/CO = 1. As the basicity of alkali promoter increases, the olefin selectivity, probability of chain growth, and CO$_2$ formation increase and methane formation decreases. The activity of CO hydrogenation increases with the pH of alkali solutions.

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Effect of 1-aminocyclopropane-1-carboxylic acid (ACC)-induced ethylene on cellulose synthase A (CesA) genes in flax (Linum usitatissimum L. 'Nike') seedlings

  • Lim, Hansol;Paek, Seung-Ho;Oh, Seung-Eun
    • Genes and Genomics
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    • v.40 no.11
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    • pp.1237-1248
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    • 2018
  • Introduction Cellulose microfibril is a major cell wall polymer that plays an important role in the growth and development of plants. The gene cellulose synthase A (CesA), encoding cellulose synthases, is involved in the synthesis of cellulose microfibrils. However, the regulatory mechanism of CesA gene expression is not well understood, especially during the early developmental stages. Objective To identify factor(s) that regulate the expression of CesA genes and ultimately control seedling growth and development. Methods The presence of cis-elements in the promoter region of the eight CesA genes identified in flax (Linum usitatissimum L. 'Nike') seedlings was verified, and three kinds of ethylene-responsive cis-elements were identified in the promoters. Therefore, the effect of ethylene on the expression of four selected CesA genes classified into Clades 1 and 6 after treatment with $10^{-4}$ and $10^{-3}M$ 1-aminocyclopropane-1-carboxylic acid (ACC) was examined in the hypocotyl of 4-6-day-old flax seedlings. Results ACC-induced ethylene either up- or down-regulated the expression of the CesA genes depending on the clade to which these genes belonged, age of seedlings, part of the hypocotyl, and concentration of ACC. Conclusion Ethylene might be one of the factors regulating the expression of CesA genes in flax seedlings.

The characteristics of democratization of fashion and fashionocracy in the global fashion industry (글로벌 패션산업에 나타난 패션 민주화의 특성과 패션 민주주의)

  • Suk, Hyojung
    • The Research Journal of the Costume Culture
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    • v.29 no.4
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    • pp.488-504
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    • 2021
  • This article examined the historical evolution of changes in the democratization of fashion, identified its characteristics, and defined 'fashionocracy - fashion democracy'- by analyzing various phenomena in the global fashion industry. This research will expand the field of fashion research and spark academic debates about fashion democracy. The democratization of fashion can be summarized in five periods; birth, introduction, early growth, growth, and maturity. The characteristics of the democratization of fashion include individual autonomy, accessibility that many people can access and enjoy, and diversity. According to the principles of democracy- "of the people, for the people, by the people" - which are based on freedom and equality, we have achieved fashion of the people and for the people so far. Furthermore, social media has shifted the balance of power to influencers and bloggers; as such, the masses who have consumed and enjoyed fashion democratization are becoming producers and promoters by actively participating in the process of making fashion, creating a new era of fashion democracy (fashionocracy): - by the people. Ultimately, fashionocracy consists of the '6P's' ; people (active and productive consumers), planet (society and environmental sustainability), products (genderless, ageless, inclusive), price (reasonable), place (multi-channel distribution, virtual spaces), and promotion (horizontal).

Effect of plant growth regulators on soybean and red bean seedling growth

  • Lee, Won Hee;Ryu, Hee La;Jeong, Eun Ju;Lee, In Jung
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.204-204
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    • 2017
  • In recent years the growth rates of world agricultural production and crop yields have slowed because of rapid urbanization but the agriculture mechanization implies the use of various power sources and improved farm tools and equipment to enhance the efficiency of utilization of various crop input. Therefore the current study was conducted to investigate the growth characteristics of seedlings treated with plant growth regulators for the production of seeds suitable for mechanical formulations of soybeans and red beans. The seeds of Uram bean and Arary red bean were sown in 128 well plug tray as the testing varieties. Three growth inhibitors such as 0.05% hexaconazole, prohexadion-calcium, and 0.1% diniconazole were treated and fifteen representative plants were collected from each treatment at 2, 5, 7, 13, 16, 17, 19, and 20 days interval after treatment. The collected plants were examined for the growth atributes such as plant height, root length, leaf area and chlorophyll. The growth promoter was treated at the 13th day after treatment with growth inhibitor and treated with 0.1% concentration of Pomina ($GA_{4+7}$ 1.8% + 6-benzylaminopurine 1.8%) and Nonaji (gibberellic acid 2% + $GA_{4+7}$ 2%). Initially the growth data was recorded to examine the effect of growth inhibitor, while after treatment with growth promoters, the growth attributes were recorded at 4th and 7th day. As a result of measuring the growth parameter of soybean, the inhibitory effect was shown in the aerobic treatment at the ground level at the 7th day after treatment. At the 4th day of growth promoting agents treatment, the stimulation effect of non - treated plants was greater than that of formalin treatments. As a result of measuring the growth attributes of red bean, In the latter part of the growth, at the 4th day after the growth promoter treatment. This study was able to confirm the effective growth regulators and treatment periods for each crop, and it was possible to control the growth of seedlings. Based on these results, it can be expected that the basis of seedling production technology of crops which is necessary for sowing and transplantation mechanization of agriculturle field can be established.

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Expression Analysis of the csp-like Genes from Corynebacterium glutamicum Encoding Homologs of the Escherichia coli Major Cold-Shock Protein CspA

  • Kim, Wan-Soo;Park, Soo-Dong;Lee, Seok-Myung;Kim, Youn-Hee;Kim, Pil;Lee, Heung-Shick
    • Journal of Microbiology and Biotechnology
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    • v.17 no.8
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    • pp.1353-1360
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    • 2007
  • Three csp-like genes were identified in the Corynebacterium glutamicum genome and designated cspA, cspB, and cspA2. The genes cspA and cspA2 encode proteins, comprising of 67 amino acid residues, respectively. They share 83% identity with each other. Identity of those proteins with Escherichia coli Csp proteins was near 50%. The cspB gene encodes a protein composed of 127 amino acids, which has 40% and 35% sequence identity with CspA and CspA2, respectively, especially at its N-terminal region. Analysis of the gene expression profiles was done using transcriptional cat fusion, which identified not only active expression of the three genes at the physiological growth temperature of $30^{\circ}C$ but also growth phase-dependent expression with the highest activity at late log phase. The promoters of cspA and cspA2 were more active than that of cspB. The expression of the two genes increased by 30% after a temperature downshift to $15^{\circ}C$, and such stimulation was more evident in the late growth phase. In addition, the cspA gene appeared to show DNA-binding activity in vivo, and the activity increased at lower temperatures. Interestingly, the presence of cspA in multicopy hindered the growth of the host C. glutamicum cells at $20^{\circ}C$, but not at $30^{\circ}C$. Altogether, these data suggest that cspA, cspB, and cspA2 perform functions related to cold shock as well as normal cellular physiology. Moreover, CspA and its ortholog CspA2 may perform additional functions as a transcriptional regulator.

Overexpression of three related root-cap outermost-cell-specific C2H2-type zinc-finger protein genes suppresses the growth of Arabidopsis in an EAR-motif-dependent manner

  • Song, Sang-Kee;Jang, Hyeon-Ung;Kim, Yo Han;Lee, Bang Heon;Lee, Myeong Min
    • BMB Reports
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    • v.53 no.3
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    • pp.160-165
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    • 2020
  • The root meristem of Arabidopsis thaliana is protected by the root cap, the size of which is tightly regulated by the balance between the formative cell divisions and the dispersal of the outermost cells. We isolated an enhancer-tagged dominant mutant displaying the short and twisted root by the overexpression of ZINC-FINGER OF ARABIDOPSIS THALIANA1 (ZAT1) encoding an EAR motif-containing zinc-finger protein. The growth inhibition by ZAT1 was shared by ZAT4 and ZAT9, the ZAT1 homologues. The ZAT1 promoter was specifically active in the outermost cells of the root cap, in which ZAT1-GFP was localized when expressed by the ZAT1 promoter. The outermost cell-specific expression pattern of ZAT1 was not altered in the sombrero (smb) or smb bearskin1 (brn1) brn2 accumulating additional root-cap layers. In contrast, ZAT4-GFP and ZAT9-GFP fusion proteins were distributed to the inner root-cap cells in addition to the outermost cells where ZAT4 and ZAT9 promoters were active. Overexpression of ZAT1 induced the ectopic expression of PUTATIVE ASPARTIC PROTEASE3 involved in the programmed cell death. The EAR motif was essential for the growth inhibition by ZAT1. These results suggest that the three related ZATs might regulate the maturation of the outermost cells of the root cap.