Journal of Animal Science and Technology

Korean Society of Animal Sciences and Technology (한국축산학회)
권호 표지
DOI QR코드

DOI QR Code

Dietary addition of a standardized extract of turmeric (TurmaFEEDTM) improves growth performance and carcass quality of broilers

  • Received : 2017.12.19
  • Accepted : 2018.04.05
  • Published : 2018.05.31
Download PDF
⟨ Previous Next ⟩

Abstract

Background: Indiscriminate use of antibiotics in livestock and poultry farming has caused emergence of new pathogenic strains. The situation has warrented the development of safe and alternative growth promoters and immunity enhancers in livestock. Herbal additives in animal and bird feed is a centuries-old practice. Thus, the present study investigated the efficacy of a standardized formulation of lipophilic turmeric extract containing curcumin and turmerones, (TF-36), as a natural growth promoter poultry feed additive. Methods: The study was designed on 180 one-day old chicks, assigned into three groups. Control group ($T_0$) kept on basal diet and supplemented groups $T_{0.5}$ and $T_1$ fed with 0.5% and 1% TF-36 fortified basal diet for 42 days. Each dietary group consisted of six replicates of ten birds. Body weight, food intake, food conversion ratio, skin colour, blood biochemical analysis and antioxidant status of serum were investigated. Results: Body weight improved significantly in $T_1$ with a 10% decrease in FCR as compared to the control. TF-36 supplementation in $T_1$ enhanced the antioxidant enzyme activity significantly (p < 0.05) with a decrease (p < 0.05) in lipid peroxidation. It also caused a slight yellow skin pigmentation without any change in meat color, indicating the bioavailability of curcumin from TF-36. However, no significant change in the concentration of serum creatinine, total protein and liver enzyme activities were observed, indicating the safety. Conclusion: In summary, we concluded that TF-36 can be a natural feed additive to improve growth performance in poultry, probably due to the better antioxidant activity and antimicrobial effects contributed by the better bioavailability of curcuminoids and turmerones. Besides, curcuminoids and turmerones were also known to be gastroprotective and anti-inflammatory agents.

Keywords

References

  1. Laxminarayan R, Van Boeckel T, Teillant A. The economic costs of withdrawing antimicrobial growth promoters from the livestock sector. 78th ed. Paris: OECD Food, Agriculture and Fisheries Papers; 2015. OECD Publishing
  2. Wegener HC. Antibiotic resistance-linking human and animal health. In: Institute of Medicine (US), editor. Improving food safety through a one health approach: workshop summary. Washington (DC): National Academies Press (US); 2012. p. A15.
  3. EU. Ban on antibiotics as growth promoters in animal feed enters into effect. http://europa.eu/rapid/press-release_IP-05-1687_en.htm. Brussels; 2005.
  4. FDA, Center for Veterinary Medicine, FDA Reminds Retail Establishments of Upcoming Changes to the Use of Antibiotics in Food Animals, https://www.fda.gov/AnimalVeterinary/NewsEvents/CVMUpdates/ucm507355.htm Rockville, Maryland, 2016.
  5. Van der Klis JD, van Eerden E. Regulation of antibiotic use in poultry production: Impact on broilers nutrition and production. In: Proc. of the 10th Mid-Atlantic Nutrition Conference, 2012: 28-29.
  6. Murugesan GR, Syed B, Haldar S, Pender C. Phytogenic feed additives as an alternative to antibiotic growth promoters in broiler chickens. Front Vet Sci. 2015;2:21.
  7. Zeng Z, Zhang S, Wang H, Piao X. Essential oil and aromatic plants as feed additives in non-ruminant nutrition: a review. J Anim Sci Biotechnol. 2015;6(1):7. https://doi.org/10.1186/s40104-015-0004-5
  8. Dhama K, Tiwari R, Khan RU, Chakraborty S, Gopi M, Karthik K, et al. Growth promoters and novel feed additives improving poultry production and health, bioactive principles and beneficial applications: the trends and advances - a review. Int J Pharmacol. 2014;10:129-59. https://doi.org/10.3923/ijp.2014.129.159
  9. Valenzuela-Grijalva NV, Pinelli-Saavedra A, Muhlia-Almazan A, Dominguez-Diaz D, Gonzalez-Rios H. Dietary inclusion effects of phytochemicals as growth promoters in animal production. J Anim Sci Technol. 2017;59:8. https://doi.org/10.1186/s40781-017-0133-9
  10. Grashorn MA. Use of phytobiotics in broiler nutrition - an alternative to infeed antibiotics? J Anim Feed Sci. 2010;19:338-47. https://doi.org/10.22358/jafs/66297/2010
  11. Prasad S, Tyagi AK, Aggarwal BB. Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice. Cancer Res Treat. 2014;46(1):2-18. https://doi.org/10.4143/crt.2014.46.1.2
  12. Singh G, Kapoor IPS, Singh P, de Heluani CS, de Lampasona MP, Catalan CAN. Comparative study of chemical composition and antioxidant activity of fresh and dry rhizomes of turmeric (Curcuma Longa Linn). Food Chem Toxicol. 2010;48(4):1026-31. https://doi.org/10.1016/j.fct.2010.01.015
  13. Liju VB, Jeena K, Kuttan R. An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L. Indian J Pharmacol. 2011;43(5):526-31. https://doi.org/10.4103/0253-7613.84961
  14. Parveen Z, Nawaz S, Siddique S, Shahzad K. Composition and antimicrobial activity of the essential oil from leaves of Curcuma longa L. Kasur variety. Indian J Pharm Sci. 2013;75(1):117-22. https://doi.org/10.4103/0250-474X.113544
  15. Park SY, Jin ML, Kim YH, Kim Y, Lee SJ. Anti-inflammatory effects of ar-turmerone through blocking of NF-kappaB, JNK, and p38 MAPK signaling pathways in amyloid beta-stimulated microglia. Int Immunopharmacol. 2012;14:13-20. https://doi.org/10.1016/j.intimp.2012.06.003
  16. Yu Y, Chen F, Wang X, et al. Evaluation of antioxidant activity of curcuminfree turmeric (Curcuma longa L.) oil and identification of its antioxidant constituents. ACS Symp Ser. 2008;993:152-64.
  17. McCord JM, Fridovich I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem. 1969;244(22):6056-63.
  18. Moron MA, Depierre JW, Mannervick B. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochim Biophys Acta. 1979;582:67-8. https://doi.org/10.1016/0304-4165(79)90289-7
  19. Hafemann DG, Sunde RA, Hoekstra WG. Effect of dietary selenium on erythrocyte and liver gluthathione peroxidase in the rat. J Nutr. 1974;104:580-4. https://doi.org/10.1093/jn/104.5.580
  20. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979;95(2):351-8. https://doi.org/10.1016/0003-2697(79)90738-3
  21. Ademola SG, Farinu G, Babatunde GM. Serum lipid, growth and haematological parameters of broilers fed garlic, ginger and their mixture. World J Agric Sci. 2009;5:99-104.
  22. Marchesi JR, Adams DH, Fava F, Hermes GDA, Hirschfield GM, Hold G, et al. The gut microbiota and host health: a new clinical frontier. Gut. 2016;65(2):330-9. https://doi.org/10.1136/gutjnl-2015-309990
  23. Hashemi SR, Davoodi H. Herbal plants and their derivatives as growth and health promoters in animal nutrition. Vet Res Commun. 2011;35:169-80. https://doi.org/10.1007/s11259-010-9458-2
  24. Gupta SC, Patchva S, Aggarwal BB. Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J. 2013;15(1):195-218. https://doi.org/10.1208/s12248-012-9432-8
  25. Bagad AS, Joseph JA, Bhaskaran N, Agarwal A. Comparative evaluation of anti-inflammatory activity of curcuminoids, turmerones, and aqueous extract of curcuma longa. Adv Pharmacol Sci. 2013:805756. https://doi.org/10.1155/2013/805756.
  26. Qasem M, Alhajj M, El Nabi G, Al-Mufarrej S. Effects of turmeric powder as a dietary supplement on performance indicators and immune responses in broiler chickens. J Animal Vet Adv. 2015;14(2):30-5.
  27. Hady MM, Zaki MM, Abd El-Ghany W, Korany Reda MS. Assessment of the broilers performance, gut healthiness and carcass characteristics in response to dietary inclusion of dried coriander, turmeric and thyme. Int J Environ Agric Res. 2013;2:153-9.
  28. Pena MM, Cuevas AC, Gonzalez EA. Evaluation of three pigment levels of marigold petals (Tagetes erecta) on skin pigmentation of broiler chicken. Tec Pecu Mex. 2004;42:105-11.
  29. Castaneda MP, Hirschler EM, Sams AR. Skin pigmentation evaluation in broilers fed natural and synthetic pigments. Poult Sci. 2005;84(1):143-7. https://doi.org/10.1093/ps/84.1.143
  30. Perez-Vendrell J, Hernandez M, Llaurado L, Schierle J, Brufau J. Influence of source and ratio of xanthophylls pigments on broiler chicken pigmentation and performance. Poult Sci. 2001;80:320-6. https://doi.org/10.1093/ps/80.3.320
  31. Tichivangana JZ, Morrissey PA. Metmyoglobin and inorganic metals as prooxidants in raw and cooked muscle systems. Meat Sci. 1985;15:107-16. https://doi.org/10.1016/0309-1740(85)90051-8
  32. Igene JO, Pearson AM. Role of phospholipids and triglycerides in warmed-over flavor development in meat model systems. J Food Sci. 1979;44:1285-90. https://doi.org/10.1111/j.1365-2621.1979.tb06420.x
  33. Chen CH, Pearson AM, Gray JI. Effects of synthetic antioxidants (BHA, BHT and PG) on the mutagenicity of IQ-like compounds. Food Chem. 1992;45:177-83.
  34. Botsoglou NA, Christaki E, Fletouris DJ, Florou-Paneri P, Spais AB. The effect of dietary oregano essential oil on lipid oxidation in raw and cooked chicken during refrigerated storage. Meat Sci. 2002;62(2):259-65. https://doi.org/10.1016/S0309-1740(01)00256-X
  35. Lopez-Bote CJ, Gray JI, Gomaa EA, Flegal CJ. Effect of dietary administration of oil extracts from rosemary and sage on lipid oxidation in broiler meat. Br Poult Sci. 1998;39:235-40. https://doi.org/10.1080/00071669889187
  36. Ri C-S, Jiang X-R, Kim M-H, Wang J, Zhang H-J, Wu S-G. Effects of dietary oregano powder supplementation on the growth performance, antioxidant status and meat quality of broiler chicks. Ital J Anim Sc. 2017;16:246-52. https://doi.org/10.1080/1828051X.2016.1274243
  37. Paraskeuas V, Fegeros K, Palamidi I, Hunger C, Mountzouris KC. Growth performance, nutrient digestibility, antioxidant capacity, blood biochemical biomarkers and cytokines expression in broiler chickens fed different phytogenic levels. Anim Nutr. 2017;3(2):114-20. https://doi.org/10.1016/j.aninu.2017.01.005

Cited by

  1. Antibiotics promote abdominal fat accumulation in broilers vol.91, pp.1, 2018, https://doi.org/10.1111/asj.13326
  2. The role of polyphenols in poultry nutrition vol.104, pp.6, 2020, https://doi.org/10.1111/jpn.13455
  3. The Impact of Dietary Curcumin on the Growth Performance, Intestinal Antibacterial Capacity, and Haemato-Biochemical Parameters of Gilthead Seabream (Sparus aurata) vol.11, pp.6, 2018, https://doi.org/10.3390/ani11061779
  4. Polyphenols and Organic Acids as Alternatives to Antimicrobials in Poultry Rearing: A Review vol.10, pp.8, 2018, https://doi.org/10.3390/antibiotics10081010
  5. Phytogenic Feed Additives in Poultry: Achievements, Prospective and Challenges vol.11, pp.12, 2018, https://doi.org/10.3390/ani11123471