• Title/Summary/Keyword: Growth phase

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Coarsening Effects on the Formation of Microporous Membranes

  • Song, Seung-Won
    • Proceedings of the Membrane Society of Korea Conference
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    • 1995.04a
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    • pp.1-4
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    • 1995
  • The microstructure of polymer membranes produced via thermally induced phase separation (TIPS) of polymer solutions is a strong function of both the early-stage (by spinodal decomposition or nucleation & growth) and the late-stage phase separation (referred to in general as coarsening). In the case of early stage effects, the membrane morphology resulting from a nucleation & growth mechanism is either a poorly interconnecsed, stringy, beady structure which is mechanically fragile or a well interconnected structure with highly nonuniform pore sizes. In contrast, spinodal decomposition results in a well interconnected, mechanically strong membrane with highly uniform pore sizes. Here I describe recent quantitative studies of the coarsening effects on the microstructure of membranes produced via TIPS process. The dependence of microstructure on coarsening time, quench depth, solution viscosity, and polymer molecular weight was investigated in order to distinguish among three possible coarsening mechanisms, Ostwald ripening, coalescence, and hydrodynamic flow, which may be responsible for structural evolution after the early-stage phase Separation (spinodal decomposition or nucleation & growth).

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The Effect of Government's Fairness as the Entrepreneur's Satisfactions & Managerial Performance: Focusing on the Differences between Start-up Companies' Growth Stage (정부의 창업지원 공정성이 만족도 및 경영성과에 미치는 영향: 창업기업의 성장단계별 차이를 중심으로)

  • Jang, Younghye;Lee, Jeonghye;Kim, Pansoo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.15 no.4
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    • pp.109-120
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    • 2020
  • This study examines how the government's fairness in entrepreneurship support affects satisfaction and management performance, and examines whether these influences are different for each growth stage of start-up companies. For this study, data were collected for start-up companies that received government support for start-up within the past 5 years. Total 611 copies of the data were used in this study. The collected data were analyzed using SPSS and AMOS. The fairness used in this study was divided into three types, procedural fairness, interactive fairness, and distributed fairness. The effect of the three fairness on the satisfaction of start-up support project was analyzed. In addition, the effect of business support satisfaction on business performance was analyzed, where the business performance was evaluated by the questioner's satisfaction with their business. The start-up phase was divided into the start phase, early growth phase, stagnant phase, and high-level growth phase, and the moderating effect between the fairness and satisfaction of the government-supported projects by start-up phase was analyzed. As a result, it was found that every concept of fairness had a positive (+) effect on the satisfaction of the entrepreneurship support project, and the satisfaction of the entrepreneurship support project had a positive (+) effect on the management performance. The concept of procedural fairness in the start phase, procedural fairness in the early growth phase, interactive fairness, and the concept of all fairness in the stagnant phase influenced the satisfaction of the start-up support project. In this study, the fairness and effect of government-supported projects affecting the management performance of start-ups were identified by growth phase of start-ups. The results of these studies will help build a systematic system for entrepreneurship support and for start-ups, it will also greatly contribute to finding differentiated growth plans by growth stages of start-up companies.

The Transient Simulation of Czochralski Single Crystal Growth Process Using New Solidification Model (새로운 응고 모델을 적용한 Czocgralski 단결정 성장 공정 모사)

  • 이경우;윤종규
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.1 no.1
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    • pp.74-81
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    • 1991
  • The temperature profile of Czochralski single crystal growth system was simulated considering the fluid flow and surface radiation heat transfer. View factors of surface elements were calculated for radiation heat transfer. Two phases(solid and liquid) were treated as a continuous phase by assigning artificial large viscosity to the solid phase and latent heat was accounted by iterative heat revolution method. The solidification model was applied to solid front of the pure Ga during the melting to verify the model. The whole simulation model of CZ system was applied to the growth Al single crystal.

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Influence of Amino Acid and Vitamin Addition on the Growth and Metabolism of a Hybridoma in Batch Culture (하이브리도마의 회분식배양에서 아미노산과 비타민의 첨가에 따른 세포성장과 대사의 변화)

  • 이동섭;박홍우
    • KSBB Journal
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    • v.13 no.3
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    • pp.289-294
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    • 1998
  • The effects of various step-fortifications of the initial medium with amino acids, glucose, and vitamines on the growth and metabolism of a hybridoma cell line in batch cultures were quantified. Comparisons between the metabolic rates of the various cultivations were made for the exponential growth phase. Fortification of the basal medium resulted in higher cell densities through a prolonged growth phase, but the maximum specific growth rate was not affected. The uptake rate of glutamine increased with the addition of amino acids but did not change upon the addition of glucose or vitamines. The specific glucose consumption decreased slightly with the addition of amino acids but increased production of lactate and {{{{ { NH}`_{4 } ^{ +} }}}}. A reciprocal relationship between the yields of {{{{ { NH}`_{4 } ^{+ } }}}} and lactate indicated a joint regulation of glycolysis and glutaminolysis.

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A Study of Intermetetallic Compound Growth in the Sn/Ni Couples(I) : Intermetallic Compound Formation and Growth Kineties (Sn/Cu 및 Sn/Ni 계면에서 금속간화합물의 형성 및 성장에 관한 연구(I) : 금속간화합물의 생성, 성장반응 및 속도론)

  • 김용혁;이성래
    • Journal of the Korean institute of surface engineering
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    • v.22 no.1
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    • pp.3-9
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    • 1989
  • The intermetallic compount formation, growth rections, and growth kinetices as functions of the aging temperaturess, time, and the condition of substarte have invedtigted in the Sn/Cu and Sn/Ni bimetal couples. The η'-phase (Cu6Sn5) and $\delta$-phase (Ni3Sn4) were only found to grow at 20 and $70^{\circ}C$in the Sn/Cu and Sn/Ni bimetallic coples repectively. Above that temperatures, all other compounds were formed in sequence of high Sn content plase and the metastable Cu41Sn11 was formed at agend $200^{\circ}C$. The ectivation energy for the growth of intermetallic compounds was 14.7Kxal/mole in the Sn/Cu interface and 26.7Kcal/mole in the Sn/Ni interface.

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Optimization of Switching Time from Growth to Product Formation for Maximum Productivity of Recombinant Escherichia coli Fermentation (유전자 재조합 대장균 발효의 최대 생산성을 위한 생육에서 제품 생성으로 전환시기의 최적화)

  • Anant Y. Patkar
    • Microbiology and Biotechnology Letters
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    • v.18 no.4
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    • pp.394-400
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    • 1990
  • Maximization of productivity of recombinant cell fermentations requires consideration of the inverse relationship between the host cell growth rate and product formation rate. The problem of maximizing a weighted performance index was solved by using optimal control theory for recombinant E. coli fermentation. Concentration of a growth inhibitor was used as a control variable to manipulate the specific growth rate, and consequently the cloned-gene expression rate. Using a simple unstructured model to describe the main characteristics of this system, theoretical analysis showed that the optimal control profile results in an initial high growth rate phase followed by a low growth rate and high product formation rate phase. Numerical calculations were done to determine optimal switching times from the growth to the production stage for two representative cases corresponding to different dependency of the product formation rate on the growth rate. For the case when product formation rate is sensitive to the specific growth rate, the optimized operation yields about 60% increase in the final product concentration compared with a simple batch fermentation.

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The Influence of Phase Feeding Methods on Growth Performance, Meat Quality, and Production Cost in Growing-Finishing Pigs (성장단계별 사료급여 방법이 육성-비육돈의 성장과 육질 그리고 생산비에 미치는 영향)

  • Jeong, Tae-Sam;Heo, Pil-Seung;Lee, Geon-Young;Kim, Dong-Hyuk;Ju, Won-Seok;Kim, Yoo-Yong
    • Journal of Animal Science and Technology
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    • v.52 no.1
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    • pp.29-36
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    • 2010
  • This experiment was conducted to evaluate the influence of phase feeding methods on growth performance, carcass characteristics, pork quality, and economical efficiency in growing-finishing pigs. A total of 120 crossbred pigs ([Yorkshire ${\times}$ Landrace] ${\times}$ Duroc), average initial body weight 25.23 ${\pm}$ 2.66 kg, were allotted to 5 treatments by body weight and sex in a randomized complete block (RCB) design. Each treatment had 6 replicates with 4 pigs per pen. The treatments were 1) A (fed late weaner feed during whole phase), 2) B (fed late weaner feed in growing phase and grower feed in finishing phase), 3) C (fed grower feed during whole phase), 4) D (fed grower feed in growing phase and early finisher feed in early and late finishing phase), 5) E (fed grower feed in growing phase, early finisher feed in early finishing phase and late finisher feed in late finishing phase). Commercial diets bought from private feed company were used for this experiment. During the early growing phase (6 wks), treatments A and B showed higher growth performance than that of other treatments (P<0.05). However, growth performance tended to be similar among treatments at 10 wks after feeding and there was no difference in time of market weight (13 wks). Moreover, blood urea nitrogen (BUN) concentration was lowered in treatment E than other treatments during whole experimental period (P<0.01). Carcass characteristics and pork quality were measured when body weight of pigs reached at 110.33 ${\pm}$ 2.1 kg. Days to market weight (110 kg), quality grade, pork color, and pork pH did not show any significant difference among treatments. These results suggested that phase feeding based upon growth stages of pigs showed no detrimental effects on growth performance and the pork quality. Moreover, feed cost was saved approximately 37% by phase feeding method without delaying of days to market weight compared to general conventional feeding method (B) of swine farm in Korea.

Effects of Methylglyoxal on the Growth Dynamics of Secenedesmus quadricauda (Methylglyoxal 이 Scenedesmus quadricauda 의 성장 역학에 미치는 영향)

  • Rhie, Ki-Tae
    • The Korean Journal of Ecology
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    • v.18 no.1
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    • pp.17-30
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    • 1995
  • The growth of Scenedesmus quadricauda (Trup.) Breb. is enhanced by methylyoxal (MG), a general inhibitor of cell division, at threshold concentration in conjunction with reatment timing relative to growth stage. The stimulatory effect of MG on algal cell growth was most significant with 2.27-fold of untreated algal culture in cell number when 0.5 mM of MG was added to the algal culture at the beginning of logarithmic phase with an initial MG concentration of 0.535 mg $MG/10^6cell$. A Specific growth rates (SGRs) of MG-treated cultures were rapidly increased at the beginning of logarithmic phase with 1.89-fold of untreated algal culture. Cultures inoculated with high cell numbers of 2.4 to 4.8 X $10^4$ cells/ml were less sensitive to 0.5 mM of MG treatment. The algal cell division was ranged from 0.392 to 0.924 mg MG/106 cell. If the cell number of an algal culture at the time of inoculation was low (0.6 X $10^4$ cells/ml) and MG was added before logarithmic phase, the cell number of 0.5 mM of MG-treated cultures were lower than those of controls. In algal cultures treated with high concentrations of MG (1.0 mM and 2.0 mM), the algal growth was inhibited. Photosynthetic rate of growth-enhanced algal by 0.5 mM of MG was significantly higher than that of untreated or 1.0 mM of MG-treated algal cell, while there was no significant difference among those groups in respiratory rate. Pyruvate concentration in 0.5 mM of MG-treated culture was incrcased agter methylglyoxal trcatment.

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Effect of Dietary sugar beet pulp supplementation on growth performance, nutrient digestibility, fecal Microflora, blood profiles and Diarrhea incidence in weaning pigs

  • Yan, C.L.;Kim, H.S.;Hong, J.S.;Lee, J.H.;Han, Y.G.;Jin, Y.H.;Son, S.W.;Ha, S.H.;Kim, Y.Y.
    • Journal of Animal Science and Technology
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    • v.59 no.8
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    • pp.18.1-18.8
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    • 2017
  • Background: In 2006, the European Union (EU) has decided to forbid use of antibiotics as growth promoters. Although many researches had been conducted about fiber source as alternatives of antibiotics, there are still lack of reports in the literature about the optimum level of sugar beet pulp supplementation, affecting growth performance and nutrient digestibility in weaning pigs. Therefore, different level of sugar beet pulp was added to diets to determine the effects of sugar beet pulp supplementation on growth performance, nutrient digestibility, fecal microflora, blood profile and incidence of diarrhea in weaning pigs. Methods: A total of 200 weaning pigs [$(Yorkshire{\times}Landrace){\times}Duroc$], averaging $9.01{\pm}1.389kg$ of initial body weight were, allotted to 5 treatments in a randomized complete block (RCB) design. Each treatment was composed of 4 replicates with 10 pigs per pen. The treatments were control treatment: Corn-SBM basal diet + ZnO (phase 1: 0.05%; phase 2; 0.03%) and four different levels of sugar beet pulp were supplemented in Corn-SBM basal diet (3, 6, 9 or 12%). Two phase feeding programs (phase 1: 1-2 weeks; phase 2: 3-5 weeks) were used for 5 week of growth trial. Results: In feeding trial, there were no significant differences in growth performance and incidence of diarrhea among treatments. The E.coli counts were not significantly different among dietary treatments but linear response was observed in Lactobacillus counts as sugar beet pulp supplementation increased (P < 0.05). In addition, IGF-1, IgA and IgG were not affected by dietary treatments. However, the BUN concentration was decreased when pigs were fed the treatments of diets with SBP compared to that of control treatment (P < 0.05). In nutrient digestibility, crude fiber and NDF digestibilities were improved as the sugar beet pulp increased (P < 0.05). However, digestibilities of crude ash, crude fat, crude fiber and nitrogen retention were not affected by dietary sugar beet pulp levels. Conclusion: This experiment demonstrated that sugar beet pulp can be supplemented in weaning pigs' diet instead of ZnO to prevent postweaning diarrhea without any detrimental effect on growth performance.

Growth Performance of Weaner Lambs Maintained on Varying Levels of Dietary Protein and Energy in the Pre-weaning Phase

  • Karim, S.A.;Santra, A.;Sharma, V.K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.10
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    • pp.1394-1399
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    • 2001
  • Influence of pre-weaning nutrition on post-weaning gain was assesses under intensive feeding in Malpura lambs. Thirty six Malpura (15 days old) lambs divided in to 3 equal groups were maintained on high (G1), medium (G2) and low (G3) energy and protein containing creep mixture with free suckling and ad libitum roughage (pala leaves: Ziziphus nummularia) up to 90 days of age. The lambs during post-weaning phase were fed on a 40:60 roughage and concentrate based composite diet to assess their post-weaning growth response. Total dry matter intake in pre-weaning phase was higher (p<0.01) in G3 than G2 and G1 while feed conversion efficiency was better in G1 than G2 and G3. The birth weight, 15 days body weight and weaning weight were however similar in the three groups. The finishing body weight, total body weight gain and average daily gain during post-weaning phase were higher (p<0.01) in G3 than in G1 and G2. The lambs in G3 consumed more (p<0.01) dry matter during post-weaning phase along with better feed conversion efficiency than other two groups. However, the DCP intake/kg body weight gain was higher in G1 than G2 and G3. Digestibility of DM, OM, CP, NDF, ADF and energy were similar among the three groups during post-weaning phase. Percent nitrogen retention as nitrogen intake was higher (p<0.01) in G3 (71.1%) than G1 (67.7%) and G2 (69.7%) during the post-weaning phase of study. The G1, G2 and G3 lambs in post-weaning phase consumed 8.1, 7.7 and 8.1 g DCP and 246.8, 227.2 and 246.1 kcal $DE/kg\;W^{0.75}/d$ and had 84.4, 80.0 and 111.1 g average daily gain, respectively. It is concluded that the lambs fed on low energy and protein containing creep mixture in pre-weaning phase showed improvement in growth during post-weaning phase under optimum feeding regime.