• Journal of Food Hygiene and Safety
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• v.24 no.3
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• pp.267-272
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• 2009

The trace element nutrient selenium discharges its well-known nutritional anti-tumor activity. Converging data from epidemiological, ecological and clinical studies have shown that selenium can decrease the risk for some types of human cancers, especially those of the prostate, lung, and colon. Mechanistic studies have indicated that selenium has many desirable attributes of chemoprevention targeting cancer cells through DNA single strand breaks, the induction of reactive oxygen species. However, there is no reports about the relationship between methylseleninic acid (MSeA), one of methylselenol metabolites and cell cycle arrest in LNCaP human prostate cancer cells. Our data showed that MSeA arrested G1/S pahse of cell cycle arrest and inhibited DNA synthesis in LNCaP cells and those cellular events by MSeA were due to the induction ofp27 protein which is a well-known cyclin-dependent kinase inhibitor. Taken together, cell cycle arrest occurred by MSeA may contribute to the growth-inhibition of prostate cancer cells.

• The Research Journal of the Costume Culture
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• v.15 no.5
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• pp.796-809
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• 2007

The viewpoint of growth pursuit is changed to that of life quality's and happiness' pursuit by modern people. Modern people in digital environment, tired of fast-changing and oppressive daily life, prefer well-being trend providing tranquility and relaxation. Well-being is related to digital, because negative influences of digital lead human-oriented, environment-friendly well-being design. Therefore the purpose of this study is to research and analyze the relation of well-being fashion design and digital environment through case study in contemporary well-being fashion design. The results of this study are as follows: 1. This study shows that the attributes of digital environment make up function-intensive, interactivity, mobility & nomad, human & emotion-oriented and environment-friendly. And this study shows the design characteristics of digital environment consist of function-intensive design by digital convergence, open structure design for interactivity, modular design for mobility & nomad, emotion-oriented & multi-sensory design and environment- friendly design. 2. Function-intensive design in modem well-being fashion composed of vogue of caports style(casual+sports), practical use of multi-functional new-healthy textiles, and popularity of many style's mixture at once. Open structure design consist of wrapover design, use of transparent materials. Modular design are layered styling, practical use of zipper and velcro. Emotion-oriented & multi-sensory design are constitute of fad of wrinkle materials, application of bright & vivid tone, personal color and family look. Environment-friendly design in contemporary well-being fashion are comprised in use of natural color, re-advent of natural floral motif and eco-design.

• Fashion & Textile Research Journal
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• v.15 no.6
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• pp.1010-1017
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• 2013

Current global textiles and fashion industries have gradually shifted focus to high value-added, high sensibility, and multi-functional products based on new human-friendliness and sustainable growth technologies. Textile design CAD systems have been developed in conjunction with computer hardware and software sector advances. This study compares the patterns or images of actual woven fabrics and virtual fabrics prepared with a textile design CAD system. In this study, several weave structures (such as fancy yarn weave and patterns) were prepared with a shuttle loom. The woven textile images were taken using a CCD camera. The same weave structure data and yarn data were fed into a textile design CAD system in order to simulate fabric images as similarly as possible. Similarity Index analysis methods allowed for an analysis of the index between the actual fabric specimen and the simulated image of the corresponding fabric. The results showed that repeated small pattern weaves provide superior similarity index values than those of a fancy yarn weave that indicate some irregularities due to fancy yarn attributes. A Complex Wavelet Structural Similarity(CW-SSIM) index resulted in a better index than other methods such as Multi-Scale(MS) SSIM, and Feature Similarity(FS) SSIM, across fabric specimen images. A correlation analysis of the similarity index based on an image analysis and a similarity evaluation by panel members was also implemented.

• The Journal of Industrial Distribution & Business
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• v.11 no.11
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• pp.39-53
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• 2020

Purpose: With a rapid advance of communication technology, distributional systems of sport contents continue to show improvements. In particular, a traditional framework in creating sport cartoon has been influenced by the environment of the communication industry. Despite the development of distributional systems, the current sport cartoon industry still lacks in advancement. To this day, various research about sport contents have been conducted; yet, not many studies of the interaction between sport cartoons and communication technology have been done. In this respect, this study is to review the distributional environment of the sport cartoon industry and provide distributional strategies for developing sport cartoon industry. Research design, data, and methodology: In addition to in-depth interviews with five practitioners in sport cartoon industry, the study employed case study methodology. Interview data were analyzed by qualitative content analysis. Results: With new environments allowing anyone allowing to create and share webtoons, various genres including sports webtoons appear, and this became amotive to the growth of sports webtoons. Today, sports comics acted as a sports advertisement platform which not only created additional profit but also became an opportunity as a marketing method. On the contrary, the formal attributes of webtoons cause hardship in consistently creating sports webtoons. Hence, it is needed that supporting policies need to be established to nurture sport webtoon expertise. For example, Korea Creative Content Agency allows future webtoon authors to have an opportunity to be educated and equipped in producing creative sport webtoon contents. Moreover, revenue systems should be developed for motivating webtoon authors to involve in sport contents in their works. Conclusions: In order to promote the sports cartoon industry based on the findings, it is first necessary to create sports comics that reflect the formal characteristics of webtoons and the changing consumer environment. Second, it is important to acknowledge the industrial value of sports comics and it is necessary to promote policies regarding sports webtoon production and distribution from a national level. Third, by diversifying profits through OSMU and sports advertisements, it is possible to enhance the work environment and the treatment of authors. Implications and future directions were discussed.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.2
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• pp.835-838
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• 2016

Background: Lung cancer remains one of the most common cancers in the world, both in terms of new cases (about 13% of total per year) and deaths (nearly one cancer death in five), because of the high case fatality. Errors in lung cancer type or malignant growth determination lead to degraded treatment efficacy, because anticancer strategy depends on tumor morphology. Materials and Methods: We have made an attempt to evaluate effectiveness of machine learning algorithms in the task of lung cancer classification based on gene expression levels. We processed four publicly available data sets. The Dana-Farber Cancer Institute data set contains 203 samples and the task was to classify four cancer types and sound tissue samples. With the University of Michigan data set of 96 samples, the task was to execute a binary classification of adenocarcinoma and non-neoplastic tissues. The University of Toronto data set contains 39 samples and the task was to detect recurrence, while with the Brigham and Women's Hospital data set of 181 samples it was to make a binary classification of malignant pleural mesothelioma and adenocarcinoma. We used the k-nearest neighbor algorithm (k=1, k=5, k=10), naive Bayes classifier with assumption of both a normal distribution of attributes and a distribution through histograms, support vector machine and C4.5 decision tree. Effectiveness of machine learning algorithms was evaluated with the Matthews correlation coefficient. Results: The support vector machine method showed best results among data sets from the Dana-Farber Cancer Institute and Brigham and Women's Hospital. All algorithms with the exception of the C4.5 decision tree showed maximum potential effectiveness in the University of Michigan data set. However, the C4.5 decision tree showed best results for the University of Toronto data set. Conclusions: Machine learning algorithms can be used for lung cancer morphology classification and similar tasks based on gene expression level evaluation.

• The Journal of the Korea Contents Association
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• v.14 no.6
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• pp.93-107
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• 2014

Recently Korean film industry has continuously experienced a rapid growth and expanded its influence to foreign countries. Accordingly, there have been numerous studies in various research areas to investigate the characteristics of the industry. In this study, we applied social network analysis based on the attributes such as genres, ratings, distributors, nationalities, sizes, and profitability to divide the movies into several clusters with respect to their similarity. Results suggested that the ratings and nationality rather than the genre are the major factors to divide the motion picture market into clusters and the profitability also varies much across the clusters. Furthermore, estimation of the diffusion model showed the positive relationship between the success of a movie and the word-of-mouth effect, while the relatively unsuccessful titles exhibited a monotonic decreasing diffusion pattern with the high initial demand and the early peak time.

• KIEAE Journal
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• v.8 no.3
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• pp.61-68
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• 2008

The development of urbanization in the twentieth century according to the rampant growth of industrialization not only brought about the improvement of life-quality but also induced us to reconsider the contemporary issues such as crisis of echo system which made us aware of the values and significance of the system and sustainable environments. As sustainability has been recognized as the holistic concept, it has been highlighted as one of the core concepts in the studies with the present ecological perspective. Particularly, as the plan of urbanization in Korea which had been based on the deconstruction has been converted into the regeneration, economic and cultural regeneration is also demanded for the future plan besides material regeneration. This study aims to scrutinize various attributes of socially sustainable designs in Yerba Buena Garden of San Francisco, USA which has been globally well known as a successful example of urban regeneration. By way of visit-and-observation of the place, the research for the study was conducted during the month of December, 2007. Three researchers visited Yerba Buena Garden to observe and take photographs and to obtain relevant data and public documents in local public library. Socially sustainable design was measured on the basis of such principles; social facilitation, permeability and accessibility, safely and emotional stability, softness and feminism, and child care convenience. Relevant data were systematically organized to support and prove the above principles. The result of the study is expected to effectively be utilized for Korean environment plan and design as a benchmarking guidelines against the crisis of degeneration and the aging society with the lowest birthrates in the world.

• Food Science and Preservation
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• v.10 no.1
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• pp.37-40
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• 2003

Coptis chinensis extract and grapefruit seed extract, natural antimicrobial substances, were applied to the dipping treatment of strawberry and incorporated in the packaging films. Strawberry was steeped in the extract solutions of 50 ppm concentration and packed with the low density polyethylene(LDPE) films incorporated with 1% extracts. During the storage at 5$^{\circ}C$, the qualities of microbial counts, awぶy ratio, texture and chemical attributes were measured for the pretreated strawberry. The LDPE films incorporated with the extracts retarded the growth of aerobic bacteria, lactic acid bacteria and yeast that had been contaminated before the pretreatment, significantly lowed the decay ratio, and gave better retention of textural firmness. The chemical and physical qualities of strawberry were not affected by the packaging films. When strawberry was steeped in the extract solutions, the effects of the packaging film incorporated with the extracts on the qualities of strawberry were accelerated.

• Korea Journal of Hospital Management
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• v.25 no.2
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• pp.25-44
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• 2020

Purposes: This study was to analyze the effects of organizational culture attributes on organizational effectiveness in newly established general hospital. Method: For this purpose, this study sampled 981 hospital employees working for E hospital opened on Apr. 1, 2019 in Seoul. A total of 981 questionnaires were distributed to them, and 888 ones responded to the survey, which had been conducted from Oct. 17, through Oct. 25, 2019. 793 responses were used for the final analysis. The data collected were processed using the SPSS 19.0K for descriptive statistics, T-test, ANOVA, Pearson's correlation coefficient and regression analysis. Findings: First, The type of organizational culture perceived most by hospital employees was 'hierarchy-oriented' (3.53) followed by 'relation-oriented'(3.33), 'task-oriented'(3.23), 'innovation-oriented'(3.19) and job satisfaction scored 3.13, organizational commitment scored 3.28 on their order. Second, 'Relation-oriented', 'task-oriented' and 'innovation-oriented' was positively correlated with job satisfaction and organizational commitment. hierarchy-oriented' was negatively correlated with job satisfaction and organizational commitment. Third, Factors that significantly influencing on organizational effectiveness in a newly established general hospital were as follows. Factors influencing job satisfaction included 'innovation-oriented', 'relation-oriented' and factors influencing organizational commitment included 'relation-oriented', 'innovation-oriented' and age. Practical Implications: In order to increase the organizational effectiveness of the E-General Hospital, it is necessary to gradually move from a hierarchica l-oriented culture to an innovation-oriented and relationship-oriented culture. Since age also affects organizational commitment, it is necessary to promote stability and growth by promoting the mentor-menti system for new members with a low level of experience and experience.

• Journal of Ecology and Environment
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• v.44 no.2
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• pp.90-97
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• 2020

Background: Natural forests are generally considered to be less prone to biological invasions than other modified ecosystems, particularly when canopy cover is high. Few decades of management of degraded forests by local communities in Nepal has increased canopy cover and altered disturbance regimes. These changes might have reduced the abundance of invasive alien plant species (IAPS) in forests. To understand the status of IAPS in such forests, we studied two community managed Shorea robusta forests (Sundari and Dhusheri) of Nawalpur district in central Nepal. In these two forests, vegetation sampling was done using circular plots 10 m radius at forest edge, gaps, and within canopy. Variation of IAPS richness and cover across these microhabitats were compared, and their variation with tree canopy cover and basal area analyzed. Result: Altogether 14 IAPS were recorded in the study forests; among them Chromolaena odorata, Ageratum houstonianum, and Lantana camara had the highest frequency. Mikania micrantha was at the early stage of colonization in Sundari Community Forest (CF) but absent in Dhuseri CF. Both IAPS cover and richness was higher at forest edge and gap than in canopy plots and both these attributes declined with increasing canopy cover and tree basal area. Conclusion: The results indicate that increase in canopy cover and closure of forest gaps through participatory management of degraded forests can prevent plant invasions and suppress the growth of previously established IAPS in Shorea robusta forests of Nepal. This is the unacknowledged benefit of participatory forest management in Nepal.