• 한국식품위생안전성학회지
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• 제24권3호
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• pp.267-272
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• 2009

우리 몸에 필수적인 미량원소인 셀레늄은 항암활성이 있는 것으로 알려져 있고, 역학적, 생태학적 그리고 임상시험을 종합해보면, 셀레늄은 종양, 특히 전립선암, 폐암, 대장암에 대한 위험성을 낮출 수 있을 것으로 생각되어진다. 기전연구에 따르면 셀레늄은 DNA single strand breaks와 활성산소종을 유도함으로써 종양을 억제하는 예방효능이 있는 것으로 밝혀지고 있다. 하지만, 아직까지 전립선암세포주에서 methylseloenol 대사체 중에 하나인 MSeA와 세포주기억제와의 관계에 대해서는 명확하게 밝혀져 있지 않은 실정이다. 따라서, 이번 연구에서는 전립선암세포주에서 셀레늄의 세포주기에 관한 효능을 확인해 보고자 하였다. 결과를 종합해보면, MSeA는 전립선암세포주에서 G1/S기 세포주기를 억제하고 DNA 합성을 방해하는 것으로 나타났고, 이러한 현상은 cyclin의존성 키나아제를 길항하는 단백질 중에 하나인 p27단백질의 발현을 증가시킴으로써 일어남을 확인하였다. 따라서, MSeA에 의해 유발되는 세포주기 억제가 전립선암 세포의 성장억제에 기여하는 것으로 사료된다.

• 복식문화연구
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• 제15권5호
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• pp.796-809
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• 2007

The viewpoint of growth pursuit is changed to that of life quality's and happiness' pursuit by modern people. Modern people in digital environment, tired of fast-changing and oppressive daily life, prefer well-being trend providing tranquility and relaxation. Well-being is related to digital, because negative influences of digital lead human-oriented, environment-friendly well-being design. Therefore the purpose of this study is to research and analyze the relation of well-being fashion design and digital environment through case study in contemporary well-being fashion design. The results of this study are as follows: 1. This study shows that the attributes of digital environment make up function-intensive, interactivity, mobility & nomad, human & emotion-oriented and environment-friendly. And this study shows the design characteristics of digital environment consist of function-intensive design by digital convergence, open structure design for interactivity, modular design for mobility & nomad, emotion-oriented & multi-sensory design and environment- friendly design. 2. Function-intensive design in modem well-being fashion composed of vogue of caports style(casual+sports), practical use of multi-functional new-healthy textiles, and popularity of many style's mixture at once. Open structure design consist of wrapover design, use of transparent materials. Modular design are layered styling, practical use of zipper and velcro. Emotion-oriented & multi-sensory design are constitute of fad of wrinkle materials, application of bright & vivid tone, personal color and family look. Environment-friendly design in contemporary well-being fashion are comprised in use of natural color, re-advent of natural floral motif and eco-design.

• 한국의류산업학회지
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• 제15권6호
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• pp.1010-1017
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• 2013

Current global textiles and fashion industries have gradually shifted focus to high value-added, high sensibility, and multi-functional products based on new human-friendliness and sustainable growth technologies. Textile design CAD systems have been developed in conjunction with computer hardware and software sector advances. This study compares the patterns or images of actual woven fabrics and virtual fabrics prepared with a textile design CAD system. In this study, several weave structures (such as fancy yarn weave and patterns) were prepared with a shuttle loom. The woven textile images were taken using a CCD camera. The same weave structure data and yarn data were fed into a textile design CAD system in order to simulate fabric images as similarly as possible. Similarity Index analysis methods allowed for an analysis of the index between the actual fabric specimen and the simulated image of the corresponding fabric. The results showed that repeated small pattern weaves provide superior similarity index values than those of a fancy yarn weave that indicate some irregularities due to fancy yarn attributes. A Complex Wavelet Structural Similarity(CW-SSIM) index resulted in a better index than other methods such as Multi-Scale(MS) SSIM, and Feature Similarity(FS) SSIM, across fabric specimen images. A correlation analysis of the similarity index based on an image analysis and a similarity evaluation by panel members was also implemented.

• 산경연구논집
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• 제11권11호
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• pp.39-53
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• 2020

Purpose: With a rapid advance of communication technology, distributional systems of sport contents continue to show improvements. In particular, a traditional framework in creating sport cartoon has been influenced by the environment of the communication industry. Despite the development of distributional systems, the current sport cartoon industry still lacks in advancement. To this day, various research about sport contents have been conducted; yet, not many studies of the interaction between sport cartoons and communication technology have been done. In this respect, this study is to review the distributional environment of the sport cartoon industry and provide distributional strategies for developing sport cartoon industry. Research design, data, and methodology: In addition to in-depth interviews with five practitioners in sport cartoon industry, the study employed case study methodology. Interview data were analyzed by qualitative content analysis. Results: With new environments allowing anyone allowing to create and share webtoons, various genres including sports webtoons appear, and this became amotive to the growth of sports webtoons. Today, sports comics acted as a sports advertisement platform which not only created additional profit but also became an opportunity as a marketing method. On the contrary, the formal attributes of webtoons cause hardship in consistently creating sports webtoons. Hence, it is needed that supporting policies need to be established to nurture sport webtoon expertise. For example, Korea Creative Content Agency allows future webtoon authors to have an opportunity to be educated and equipped in producing creative sport webtoon contents. Moreover, revenue systems should be developed for motivating webtoon authors to involve in sport contents in their works. Conclusions: In order to promote the sports cartoon industry based on the findings, it is first necessary to create sports comics that reflect the formal characteristics of webtoons and the changing consumer environment. Second, it is important to acknowledge the industrial value of sports comics and it is necessary to promote policies regarding sports webtoon production and distribution from a national level. Third, by diversifying profits through OSMU and sports advertisements, it is possible to enhance the work environment and the treatment of authors. Implications and future directions were discussed.

• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.835-838
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• 2016

Background: Lung cancer remains one of the most common cancers in the world, both in terms of new cases (about 13% of total per year) and deaths (nearly one cancer death in five), because of the high case fatality. Errors in lung cancer type or malignant growth determination lead to degraded treatment efficacy, because anticancer strategy depends on tumor morphology. Materials and Methods: We have made an attempt to evaluate effectiveness of machine learning algorithms in the task of lung cancer classification based on gene expression levels. We processed four publicly available data sets. The Dana-Farber Cancer Institute data set contains 203 samples and the task was to classify four cancer types and sound tissue samples. With the University of Michigan data set of 96 samples, the task was to execute a binary classification of adenocarcinoma and non-neoplastic tissues. The University of Toronto data set contains 39 samples and the task was to detect recurrence, while with the Brigham and Women's Hospital data set of 181 samples it was to make a binary classification of malignant pleural mesothelioma and adenocarcinoma. We used the k-nearest neighbor algorithm (k=1, k=5, k=10), naive Bayes classifier with assumption of both a normal distribution of attributes and a distribution through histograms, support vector machine and C4.5 decision tree. Effectiveness of machine learning algorithms was evaluated with the Matthews correlation coefficient. Results: The support vector machine method showed best results among data sets from the Dana-Farber Cancer Institute and Brigham and Women's Hospital. All algorithms with the exception of the C4.5 decision tree showed maximum potential effectiveness in the University of Michigan data set. However, the C4.5 decision tree showed best results for the University of Toronto data set. Conclusions: Machine learning algorithms can be used for lung cancer morphology classification and similar tasks based on gene expression level evaluation.

• 한국콘텐츠학회논문지
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• 제14권6호
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• pp.93-107
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• 2014

최근 한국 영화시장은 높은 성장률을 거듭하면서 그 영향력을 해외로 넓히고 있다. 그에 따라 다양한 학문 영역에서 영화시장의 특성을 분석하기 위한 시도가 이루어져 왔다. 본 연구에서는 영화 간의 유사성과 관련성을 기반으로 한 사회 연결망 분석을 통해 국내 시장에서 개봉된 영화들을 몇 개의 군집으로 나누어 그 특성을 분석하였다. 장르, 등급, 배급사, 국적, 규모, 수익성 등의 여러 특성을 활용하여 얻은 연결망은 몇 개의 군집으로 나뉘며, 각각의 군집에 대하여 군집을 규정지을 수 있는 대표적인 특성과 군집 별대표로 선정된 영화들의 특성을 살펴보았다. 분석결과 장르에 비해 상영등급과 국적이 전체 영화시장을 각각의 군집으로 나누는 중요한 기준인 것으로 나타났으며, 영화의 수익성에 있어서도 군집 간 차이가 두드러졌다. 더 나아가 확산 모형의 추정 결과는 영화의 성공과 입소문 효과의 연관성을 보여주고 있으며, 상대적으로 성공을 거두지 못한 영화들의 경우에는 높은 초기수요와 빠른 최대 시점을 갖는 단조 감소의 확산 패턴을 가지는 것으로 나타났다.

• KIEAE Journal
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• 제8권3호
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• pp.61-68
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• 2008

The development of urbanization in the twentieth century according to the rampant growth of industrialization not only brought about the improvement of life-quality but also induced us to reconsider the contemporary issues such as crisis of echo system which made us aware of the values and significance of the system and sustainable environments. As sustainability has been recognized as the holistic concept, it has been highlighted as one of the core concepts in the studies with the present ecological perspective. Particularly, as the plan of urbanization in Korea which had been based on the deconstruction has been converted into the regeneration, economic and cultural regeneration is also demanded for the future plan besides material regeneration. This study aims to scrutinize various attributes of socially sustainable designs in Yerba Buena Garden of San Francisco, USA which has been globally well known as a successful example of urban regeneration. By way of visit-and-observation of the place, the research for the study was conducted during the month of December, 2007. Three researchers visited Yerba Buena Garden to observe and take photographs and to obtain relevant data and public documents in local public library. Socially sustainable design was measured on the basis of such principles; social facilitation, permeability and accessibility, safely and emotional stability, softness and feminism, and child care convenience. Relevant data were systematically organized to support and prove the above principles. The result of the study is expected to effectively be utilized for Korean environment plan and design as a benchmarking guidelines against the crisis of degeneration and the aging society with the lowest birthrates in the world.

• 한국식품저장유통학회지
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• 제10권1호
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• pp.37-40
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• 2003

딸기를 항균소재에 침지 처리한 후 1% 농도로 항균성 소재를 첨가시킨 저밀도폴리에틸렌(LDPE) 필름에 의하여 딸기를 싸서 포장하고 5$^{\circ}C$에 저장하면서 미생물 성장, 부패율, 텍스쳐, 화학적 품질을 측정한 결과 대조구에 비교해서 긍정적인 결과를 얻을 수 있었다. 즉, 항균성 소재를 포함시킨 LDPE 필름은 무첨가 대조 필름에 비해 호기성 총균수, 효모/곰팡이수로 측정된 미생물의 증식을 억제하는 것으로 나타났다. 이러한 미생물 증식억제의 효과로 인하여 항균성 필름은 포장된 딸기의 부패율을 낮추어 주고, 연화를 억제하였다. 딸기의 저장 중 pH는 상승하고 적정산도는 감소하였으며 가용성 고형분은 감소하는 경향을 보였으나 포장 처리구간에는 유의하고 일관성있는 차이를 발견할 수 없었다. 대조구 LDPE에 비교해서 항균필름의 효과를 재확인 할 수 있었으며, 황련추출물 및 GFSE등과 같은 항균소재에의 침지 처리과정을 항균필름 포장 방법과 병행하여 사용함으로써 딸기의 신선도를 연장하는 효과를 극대화 할 수 있음을 확인하였다. 이상의 연구결과로 미루어, 본 연구에서 그 기능과 효과를 구명한 천연항균소재는 수확한 딸기의 항균용처리제재 및 포장 필름 소재로 선도유지효과를 기대할 수 있어, 딸기의 생산기반 보호와 농가소득에 큰 도움이 될 것으로 생각된다.

• 한국병원경영학회지
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• 제25권2호
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• pp.25-44
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• 2020

Purposes: This study was to analyze the effects of organizational culture attributes on organizational effectiveness in newly established general hospital. Method: For this purpose, this study sampled 981 hospital employees working for E hospital opened on Apr. 1, 2019 in Seoul. A total of 981 questionnaires were distributed to them, and 888 ones responded to the survey, which had been conducted from Oct. 17, through Oct. 25, 2019. 793 responses were used for the final analysis. The data collected were processed using the SPSS 19.0K for descriptive statistics, T-test, ANOVA, Pearson's correlation coefficient and regression analysis. Findings: First, The type of organizational culture perceived most by hospital employees was 'hierarchy-oriented' (3.53) followed by 'relation-oriented'(3.33), 'task-oriented'(3.23), 'innovation-oriented'(3.19) and job satisfaction scored 3.13, organizational commitment scored 3.28 on their order. Second, 'Relation-oriented', 'task-oriented' and 'innovation-oriented' was positively correlated with job satisfaction and organizational commitment. hierarchy-oriented' was negatively correlated with job satisfaction and organizational commitment. Third, Factors that significantly influencing on organizational effectiveness in a newly established general hospital were as follows. Factors influencing job satisfaction included 'innovation-oriented', 'relation-oriented' and factors influencing organizational commitment included 'relation-oriented', 'innovation-oriented' and age. Practical Implications: In order to increase the organizational effectiveness of the E-General Hospital, it is necessary to gradually move from a hierarchica l-oriented culture to an innovation-oriented and relationship-oriented culture. Since age also affects organizational commitment, it is necessary to promote stability and growth by promoting the mentor-menti system for new members with a low level of experience and experience.

• Journal of Ecology and Environment
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• 제44권2호
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• pp.90-97
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• 2020

Background: Natural forests are generally considered to be less prone to biological invasions than other modified ecosystems, particularly when canopy cover is high. Few decades of management of degraded forests by local communities in Nepal has increased canopy cover and altered disturbance regimes. These changes might have reduced the abundance of invasive alien plant species (IAPS) in forests. To understand the status of IAPS in such forests, we studied two community managed Shorea robusta forests (Sundari and Dhusheri) of Nawalpur district in central Nepal. In these two forests, vegetation sampling was done using circular plots 10 m radius at forest edge, gaps, and within canopy. Variation of IAPS richness and cover across these microhabitats were compared, and their variation with tree canopy cover and basal area analyzed. Result: Altogether 14 IAPS were recorded in the study forests; among them Chromolaena odorata, Ageratum houstonianum, and Lantana camara had the highest frequency. Mikania micrantha was at the early stage of colonization in Sundari Community Forest (CF) but absent in Dhuseri CF. Both IAPS cover and richness was higher at forest edge and gap than in canopy plots and both these attributes declined with increasing canopy cover and tree basal area. Conclusion: The results indicate that increase in canopy cover and closure of forest gaps through participatory management of degraded forests can prevent plant invasions and suppress the growth of previously established IAPS in Shorea robusta forests of Nepal. This is the unacknowledged benefit of participatory forest management in Nepal.