• 대한약침학회지
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• 제25권1호
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• pp.63-67
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• 2022

Black soybean (BS) is widely thought to prevent or alleviate hair loss, which has been demonstrated by in vitro experiments. However, few clinical studies have directly assessed the effect of BS on hair growth. To assess the safety and efficacy of BS, we administered BS extract to 10 adult patients for 3 months without any other hair products and treatments. The number and diameter of hair lost from washing were examined every 4 weeks. In addition, the participants' satisfaction with their hair condition was also measured using the VAS (1 to 10) before and after treatment. The mean number of lost hair was 140.7 (SD 59.4) at baseline and 38.8 (SD 54.4) after 12 weeks, and the diameter of lost hair was 72.4 ㎛ (SD 11.9) at baseline and 80.4 ㎛ (SD 8.8) after 12 weeks, which indicated a statistically significant improvement (p = 0.002, p = 0.022, paired t-test). The satisfaction score was significantly increased from 6.10 (SD 1.2) to 8.2 (SD 1.1) after 12 weeks. These results suggest that BS extract may promote hair growth and prevent hair loss.

• Journal of Microbiology and Biotechnology
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• 제33권9호
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• pp.1119-1129
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• 2023

Seeds are colonized by diverse microorganisms that can improve the growth and stress resistance of host plants. Although understanding the mechanisms of plant endophyte-host plant interactions is increasing, much of this knowledge does not come from seed endophytes, particularly under environmental stress that the plant host grows to face, including biotic (e.g., pathogens, herbivores and insects) and abiotic factors (e.g., drought, heavy metals and salt). In this article, we first provided a framework for the assembly and function of seed endophytes and discussed the sources and assembly process of seed endophytes. Following that, we reviewed the impact of environmental factors on the assembly of seed endophytes. Lastly, we explored recent advances in the growth promotion and stress resistance enhancement of plants, functioning by seed endophytes under various biotic and abiotic stressors.

• International Journal of Advanced Culture Technology
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• 제12권2호
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• pp.51-61
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• 2024

This study analyzes and compares the roles and significance of large firms in economic growth by differentiating developmental stages. The focus is on both the role of big businesses on the road from middle- to high-income countries and the performance in their economies. By classifying the top 30 nonfinancial firms into their origin countries, we have constructed a country-level data basis covering 33 countries ranging from middle- to high-income economies for the 2001 to 2017 period. We conduct fixed effect estimation. Empirical results show that capital-intensive big businesses would be more predominant in developed economies. In terms of policy implications, the results suggest that if policymakers want to optimize the role of big businesses in economic growth, policymakers need to distinguish the income level. Policymakers also need to adjust the size distribution of firms moderately ahead of time to create the size distribution of firms needed to take the economy to the next level.

• 대한한의학회지
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• 제38권4호
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• pp.90-103
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• 2017

Objectives: This study was designed to confirm the effects of the Korean Medicine health promotion program targeting young children. One important aspect of the Korean Medicine health promotion program for children is to bring awareness of health benefits of introducing Korean Medicine methods to young children and to promote incorporating such methods in children's daily activities to develop healthy habits. Methods: The following experiment was conducted for 6 weeks, and the participants were in the age between 2 to 6 years old from 6 child care centers in Wonju and Chungju. 268 participants were in the intervention group, and 277 in the control group. To measure the outcomes of the Children Korean Medicine health program, the intervention group received Korean Medicine prevention programs (children education, parent education, growth exercises, common cold prevention scarf, and pear herb tea), control group did not. This research collected and compared the following data as the children's health indicators to measure the outcomes before and after the program: medical services usage, the number of absences, early leaves, and tardiness to the child care centers due to the participant's health condition. Results: After applying the children's health promotion programs on children between the age of 2-6, there was a decrease in the overall medical services usage, absences, early leaves, and tardiness to the child care center. This health promotion program was purely based on Korean medical theories and Korean Medicine resources without any conventional medical mediation. Conclusions: It can be concluded that a positive change was noted in raising awareness of Korean Medicine through educating both the parents and children. By learning to incorporate Korean Medicine prevention practices to daily habits, not only was there a reduction in the Medical services usage, but the children also became familiar and comfortable with Korean Medicine and its treatment procedures; the overall satisfaction level of the program was also high.

• 보건행정학회지
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• 제17권4호
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• pp.54-81
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• 2007

The paradigm of health promotion requests community participation and its active problem-solving. Community is conceptualized as a resource pool to be organized. Such resource is called community capacity. Community participation is a process of capacity building. Community voluntary associations are considered as valuable resource to be used for health promotion. This paper tried to identify the network structure among community voluntary associations and to infer the possibility to make such network of organizations participate in health promotion programs. Two survey data were used for this research: 1) Measurements and Evaluations of Community Capacity on Dobong-gu (N=94) 2) A development plan of health medicine service to be Healthy Gangdong-gu (N=69). The questionnaire included such variables measuring community capacity as leadership, membership, organizational resources, and inter-organizational network, etc. Both regions had the following common characteristics: 1) There were positive correlations between the organization's budget and membership. 2) Organizational types were associated with their founded years. Two regions showed the following differences: Dobong displayed the high density of community organizations, but Gangdong showed the low density. Dobong community organizations were able to be classified into three network clusters such as women & environments, youth & adolescent, and sports organizations. Each cluster of organizations favored the different type of health promotion programs. Gangdong community organizations were less developed, and not possible to be clustered. Depending upon the level of community capacity or community organizations' differentiation, the strategy of community participation could be settle down in different ways. Particularly the health agency had to pay more attention to support the growth of civil organizations.

• 대한의용생체공학회:의공학회지
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• 제44권4호
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• pp.225-241
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• 2023

The study empirically analyzed the differences in industry distribution and innovation activity performance in the metropolitan and non-metropolitan areas of Korea's bio companies, which are highlighted as future growth engines. The main innovation activities of the bio industry, which are focused on science and technology and expressed with high uncertainty, were analyzed, centering on human resources, technology cooperation, and investment promotion. As a result of the analysis, the biomedical industry in the metropolitan area was found to have a high proportion, and bio foods, bio-based chemicals, and energy industries in the non-metropolitan area, respectively. Moreover, the innovation activity performances differed between the two regions. In particular, the notable characteristics included human resources, investment promotion, and technical cooperation with medical institutions in the metropolitan area with a high proportion of biomedical industries, and technology personnel exchange and cooperation with private research institutions in the non-metropolitan area, which has a high proportion of bio foods, bio-based chemicals, and energy industries. This study is significant in that it is the first study to compare and analyze the performance of innovative activities based on the distribution of industries in the bio-industry, focusing on human resources, technology cooperation, and investment promotion. In addition, after investigating the distribution status and competitiveness of the domestic bio-industry by region, it will analyze the status and characteristics of the domestic bio-industry and present policy implications to implement relevant promotion policy more efficiently.

• 미생물학회지
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• 제48권1호
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• pp.16-21
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• 2012

여러 식물의 근권에서 세균 균주들을 분리하여 이들의 항진균성 물질 생성능을 조사하였다. 분리균주 중 Fusarium oxysproum을 포함한 5가지 주요 식물병원성 진균에 대한 생장저해가 우수한 7개 균주를 16S rRNA 유전자 염기서열로 동정하였다. 이들 중 Paenibacillus peoriae RhAn32, Pseudomonas otitidis TK1과 Bacillus cereus TK2가 가장 넓은 생장 저해범위를 나타내었으며 항진균성 물질 중 siderophore 생성능은 P. otitidis TK1이 3.21 mM/ml로 가장 높았고 HCN은 Pseudomonas koreensis Rh2와 Rh7 균주만이 생성하였으며 Brevibacterium frigoritolerans EnA9와 P. peoriae RhAn32는 각각 1558.9와 $1436.7{\mu}M$ glucose/min/mg protein의 높은 chitinase 활성을 나타내었다. P. otitidis TK1과 P. peoriae RhAn32의 항진균능을 진균과의 공동배양을 통해 정량분석한 결과 세 종류의 Fusarium oxysproum의 생장을 유의성 있게 저해하였다. P. otitidis TK1은 식물생장을 촉진하는 호르몬인 auxin의 생성능도 가장 높았는데 이 균주를 4주 자란 토마토 유묘에 F. oxysporum f. sp. lycopersici와 동시에 접종하여 8주간 재배하였을 때 줄기와 뿌리 길이 및 습윤 중량이 비접종 대조군에 비해 각각 45.7, 64.9와 118%로 유의성 있게 증가하였다. 따라서 이 균주들은 유기합성농약을 대체하면서 식물생장을 촉진하는 미생물제로서의 적용이 가능할 것으로 기대된다.

• Journal of Microbiology and Biotechnology
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• 제24권1호
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• pp.106-112
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• 2014

Very few plant growth-promoting rhizobacteria (PGPR) are known to produce gibberellins (GAs). The current study aimed to isolate a phytohormone-producing PGP rhizobacterium from soil and assess its potential to enhance plant growth. The newly isolated bacterium was identified as Leifsonia soli sp. SE134 on the basis of partial 16S ribosomal RNA gene sequence. Application of L. soli culture filtrate significantly increased the biomass, hypocotyl, and root lengths of cucumber seeds as compared with non-inoculated sole medium and distilled water treated controls. Furthermore, the PGPR culture was applied to the GA-deficient mutant rice cultivar Waito-C. Treatment with L. soli SE134 significantly increased the growth of Waito-C rice seedlings as compared with controls. Upon chromatographic analysis of L. soli culture, we isolated, detected and quantified different GAs; namely, $GA_1$ ($0.61{\pm}0.15$), $GA_4$ ($1.58{\pm}0.26$), $GA_7$ ($0.54{\pm}0.18$), $GA_8$ ($0.98{\pm}0.15$), $GA_9$ ($0.45{\pm}0.17$), $GA_{12}$ ($0.64{\pm}0.21$), $GA_{19}$ ($0.18{\pm}0.09$), $GA_{20}$ ($0.78{\pm}0.15$), $GA_{24}$ ($0.38{\pm}0.09$), $GA_{34}$ ($0.35{\pm}0.10$), and $GA_{53}$ ($0.17{\pm}0.05$). Plant growth promotion in cucumber, tomato, and young radish plants further evidenced the potential of this strain as a PGP bacterium. The results suggest that GA secretion by L. soli SE134 might prove advantageous for its ameliorative role in crop growth. These findings can be extended for improving the productivity of different crops under diverse environmental conditions.

• 산업진흥연구
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• 제7권3호
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• pp.77-83
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• 2022

본 연구는 개인의 성장과정에서 불안정 애착을 경험한 중년여성이 자신의 성장 과정을 재조명함으로써 긍정적인 변화를 경험하도록 돕는 목적으로 수행되었다. 본 연구 기간은 2020년 8월부터 2021년 9월까지 총 14회기에 걸쳐 심층 면담을 진행하였고, 면담 내용은 내러티브 연구방법론에 따라 참여자의 불안정 애착과 외상 후 성장에 관한 경험의 의미를 존재적 맥락, 관계적 맥락, 생애적 맥락 등으로 텍스트를 기술하였다. 연구결과는 불안정 애착과 외상 후 성장을 경험한 참여자 3명을 선정하여 다음과 같은 결론이 도출되었다. 첫째, 존재적 맥락에서의 의미는 인정 받기 위한 욕구, 완벽주의, 불안한 가정환경, 스트레스 대처방법, 상처를 마주할 용기, 자기수용 및 긍정, 주변 사람들에게 감사, 삶의 희망은 참여자 경험 속에서 의미로 해석하였다. 둘째, 관계적 맥락에서의 의미는 부모, 남편, 자녀, 대인관계, 종교와의 경험으로 해석하였다. 셋째, 생애적 맥락에서의 의미는 돌봄의 결핍, 통제의 재현, 장녀로의 책임감, 소중한 가정, 삶의 의미와 가치는 과거 부모와의 다양한 경험이 현재 참여자들의 삶에 영향을 미치는 현재의 경험 속에서 해석하였다. 이상의 연구 결과를 통해 본 연구는 내러티브 기법으로 참여자들의 어린 시절 불안정 애착 경험과 외상 후 성장 과정을 기술하고 그들의 삶에 긍정적인 대안을 제시하고자 한다.

• Journal of Plant Biotechnology
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• 제49권4호
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• pp.356-361
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• 2022

본 연구에서는 Bacillus amyloliquefaciens ISP-5 균주의 최적배지조성을 확인하기 위해 5종의 탄소원(glucose, fructose, sucrose, maltose, corn starch)과 5종의 질소원(yeast extract, peptone, tryptone, soytone, soy bean flour)을 이용하여 각각의 생육을 측정하였다. 그 결과 glucose와 soy bean flour를 각각 최적 탄소원과 질소원으로 확립하였으며 최적 배지를 이용하였을 때 상업용 배지(TSB)에 비해 약 2500배의 생육을 확인할 수 있었다. B. amyloliquefaciens ISP-5 배양액을 상추에 엽면 살포하였을 때 상추의 엽폭과 엽장은 대조군에 비해 8.6%, 12.9%의 증가하였으며, 생체중과 건물중은 대조군에 비해 각각 24.2%, 23.9% 증가하였다. 이러한 결과들을 종합해보았을 때 B. amyloloiquefaciens ISP-5 균주를 이용한 미생물 제제는 상추용 식물생장촉진제로써 활용할 수 있을 것이라 기대된다.