• 산업경영시스템학회지
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• 제43권2호
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• pp.65-71
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• 2020

Worldwide plant market keeps maintaining steady growth rate and along with this trend, domestic plant market and its contractors also maintain such growing tendency. However, in spite of its external growth, win-win growth of domestic material industry that occupies the biggest share in plant industry cost portion is extremely marginal in reality. Domestic plant material suppliers are required to increase awareness of domestic material brand by securing quality and reliability of international standard through improvement of design quality superior to that of overseas material suppliers. Improvement of design quality of plant material becomes an essential element, not an option, for survival of domestic plant industry and its suppliers. Under this background, in this study, priority and importance by each evaluation index was analyzed by materializing plant design stage through survey of experts and defining evaluation index by each design stage and based on this analysis result, evaluation index of stage-gate based decision-making process that may improve design quality of plant material was suggested. It is considered that by utilizing evaluation index of stage-gate based decision-making process being suggested in this study, effective and efficient decision-making of project decision-makers would be enabled and it would be contributory to improve design quality of plant material.

• 한방안이비인후피부과학회지
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• 제20권1호통권32호
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• pp.27-37
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• 2007

Background and Objective : Psoriasis is a chronic skin disease characterized by angiogenesis. It has been reported that growth factor as vascular endothelial growth factor (VEGF) and insulin-like growth factor (IGF)-II are overexpressed in psoriatic epidermis. This stydy was carried out for whether SB extracts have an anti-angiogenic effect for angiogenic factor. Method : To investigate the inhibitory effect of VEGF expression by the SB extracts, we performed MTS assay, western blots using HaCaT cells. HaCaT cells were pretreated with SB extracts for 1 hour followed by treatment with IGF-II. Result : SB extracts significantly reduced IGF-II induced HIF-1 ${\alpha}$ protein level via p53 and MAPK pathway in HaCaT cells. Also, SB extracts inhibited IGF-II induced VEGF mRNA and protein expression levels in the HaCaT keratinocytes. Conclusion : These results suggest that inhibition of HIF-1 ${\alpha}$ and VEGF expressions by SB extracts contributes to the anti-angiogenic effects.

• 대한건축학회논문집:계획계
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• 제34권10호
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• pp.95-106
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• 2018

Currently, the way of providing housing in Korea has been regarded as public rental housing through large-scale development by the government. However, there is an increasing need for qualitative growth not only in quantitative growth but also in policies, systems, and sustainable design. The purpose of this study is to explore the applicable methods for domestic social housing through the policy and design guideline study of UK social housing which has achieved qualitative growth through diversification of development subject. First, the concept of social housing in the UK and sustainable housing design elements will be examined. Second, the characteristics and policy direction, project background, management and sustainability of five social housing projects over the last 10 years in the UK will be analyzed. In conclusion, in order to achieve the sustainable design of social housing, the construction of the social housing in terms of policy and environment must include safe and eco-friendly design adaptability that can secure local identity and respond flexibly to social change. In addition, the social housing in the UK, which forms a sustainable complex through cooperation between the public and the private sector based on its place and history, can be a guideline for establishing policies and design guidelines in terms of urban regeneration.

• The Journal of Asian Finance, Economics and Business
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• 제9권8호
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• pp.81-88
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• 2022

For each country, the growth of the country is significantly associated with the growth of the manufacturing industry. Especially in the early stages of development, the manufacturing industry has greatly played a great role in creating great added value for society and economic development in that country. Starting from a country with a weak manufacturing background, Vietnam is gradually opening up and integrating into the global economy, which has brought many opportunities for manufacturing enterprises in particular and the enterprise community in general, making Vietnam one of the countries with large production activities in Southeast Asia and Asia. The study evaluates the factors affecting the financial performance of manufacturing enterprises through a case study in Hanoi, Vietnam. Using a survey sample of 235 enterprises operating in production and using quantitative analysis methods, the research results show that: Enterprises with high governance quality are enterprises with high economic efficiency or enterprises with low management capacity have low business efficiency. Moreover, large-scale enterprises often have many advantages in seeking profits and improving business efficiency. Finally, the study has some recommendations to improve corporate governance and growth, create a stronger business community and contribute more to Vietnam's economic development.

• 정보교육학회논문지
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• 제19권1호
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• pp.127-138
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• 2015

핀란드는 우수한 교육정책과 선진화된 교육 시스템으로 세계에서 가장 선진화된 교육을 실시하는 나라로 일컬어진다. 핀란드와 우리나라의 역사적 배경 및 지리적 환경 등은 여러 가지 면에서 흡사하며, 자원이 부족하여 국가의 성장 동력을 우리나라와 마찬가지로 인재양성에 두었다. 그러나 최근 2012년 실시한 PISA의 결과에서 급격한 하락세를 보이고 있으며, 컴퓨터관련 교육은 미흡하다는 지적과 함께 인접한 국가들의 소프트웨어 교육에 대한 국가수준 추진 전략 등으로 소프트웨어 교육에 대한 논의가 높아졌다. 따라서 2016년은 소프트웨어교육을 통한 국가 성장의 기회로 삼을 수 있는 중요한 해가 되었고, 필수교육과정으로써 초등학교에서부터 본격적으로 실시하도록 준비하였다. 본 연구에서는 핀란드의 소프트웨어 교육의 배경과 교육과정에 대해 살펴보고 우리나라의 소프트웨어 교육과정 수립에 시사하는 바를 도출하여 제시하고자 한다.

• 디자인학연구
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• 제14권4호
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• pp.57-64
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• 2001

한국의 자동차산업은 1980넌대와 1990년대 초까지 고도 성장기를 거치면서 자동차메이커의 수가 일곱 개에까지 이르는 등 급격한 양적 팽창을 하였으나, 1990년대 후반 이후에 밀려온 자동차산업에서의 전 세계적인 구조조정의 영향으로 규모의 경제를 실현하면서 내실을 기하기 위하여 인수와 합병 등의 방법을 통하여 변화되기에 이르렀다. 산업규모의 양적인 팽창에 치우쳤던 과거의 발전 방향에 비추어 볼 때, 단순한 기계제품, 또는 산업제품 이라기보다는 문화적 인식과 조형적 접근이 요구되는 자동차라는 독특한 공업제품은 그를 뒷받침 할만한 한국 사회의 전반적인 자동차에 대한 문화적 이해가 상대적으로 적었다. 이것은 자동차 산업을 수출 중심의 경제 발전을 위한 도구로써 인식한데서 기인한 한계로 볼 수 있다. 오랜 역사와 굴지의 규모를 가진 자동차 선진국의 예에서 살펴보듯이 자동차는 단순한 기계제품이나 상품으로써 가 아니라, 문화적 배경을 가지는 생활 도구로써의 접근이 요구되며, 그러한 인식을 통해서 세계시장에서 독자성을 가질 수 있는 품질과 디자인의 개발이 가능하다 글로벌 경쟁 체제에 들어간 21세기 한국의 자동차디자인과 산업의 당면과제는 외곽상품의 모방적인 개발 방식에서 탈피하여 한국 사회만의 문화적 특성을 정립시켜 대중적 인식 확대를 통한 독자성의 확보이며, 이를 위한 사회의 간접부분으로써 박물관의 역할이 더욱 중요하다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권2호
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• pp.613-619
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• 2015

Background: Hepatocellular carcinoma (HCC) is the commonest primary malignant cancer of the liver in the world. Insulin-like growth factor-1 (IGF-1) levels reflect hepatic function and are inversely correlated with the severity of background chronic liver disease. Objective: This study evaluated whether basal serum IGF-1 levels can predict prognosis of HCC patients according to different risks of disease progression. Materials and Methods: A total of 89 patients with hepatocellular carcinoma (HCC) were recruited in 3 groups: Group I, 30 HCC patients receiving sorafinib; Group II, 30 HCC patients with best supportive care; and Group III include 29 patients undergoing transcatheter arterial chemoembolization (TACE). All patients were investigated for serum levels of AST, ALP, Bb, Cr, BUN, AFP and IGF-I. Results: Patients with disease control had significantly higher baseline IGF-1 levels 210 (185-232.5) ng/mL (p value<0.01) than did patients without disease control. Low basal IGF-1 levels were associated with advanced HCC, such as multiple tumors and advanced stage, and low IGF-1 levels predicted shorter TTP and overall survival in patients treated with TACE. Conclusions: The levels of serum IGF-1, expressed as continuous values, may be helpful for accurately assessing hepatic function and the prognostic stratification of patients with HCC.

• 산업경영시스템학회지
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• 제45권4호
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• pp.210-216
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• 2022

The army is concerned about the decrease in enlistment resources due to the low birth rate and the weakening of military combat power due to the shortening of the military service period. Now, the military's quantitative growth is no longer limited and it is a time for qualitative growth. To this end, the Army has been applying the Israeli learning method Havruta to recruit training to improve the quality of training since 2019. After applying Havruta, several scholars have studied the effect of recruit training applying Havruta. As a result, it was verified that recruit training applying Havruta improves the inner motive, creativity, and military service value of trainees. This study investigated how trainees' inner motive, creativity, and military service value affect their satisfaction and achievement. In addition, it was studied whether the effect of recruit training applied with Havruta on achievement differs according to the educational background (high school graduate or higher) and military family (professional soldiers within 4th degree) of the trainees. To this end, a survey was conducted on 472 recruits, and the structural relationship between each variable and the moderating effect were analyzed using the structural equation model. As a result of the study, military service value did not affect training satisfaction. Also, there was a difference in the effect of creativity on training satisfaction according to the educational background of new recruits, and there was a difference in the effect of military service value on training satisfaction and training achievement according to military family members. The purpose of this study is to contribute to the improvement of the army's recruit training development plan and effective training system.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2022년도 추계학술대회
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• pp.272-272
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• 2022

Water and phosphorus (P) fertilizer are two of the most critical inputs in rice cultivation. Under climate change scenarios and urbanization, irrigation and fertilizer are becoming limiting factors often leading to significant decrease in yield whenever supplied scarcely. It has been shown that the Pup1 QTL confers tolerance to P starvation and improved early-stage root vigor in indica rice grown in the tropics. However, whether the QTL works in japonica rice genetic background grown in temperate regions remains to be elucidated. Here, we have introgressed the Pup1 QTL into three temperate rice varieties MS11, TR22183, and Dasan using marker-assisted backcrossing and next generation sequencing. The selected lines all harbored the full Pup1 QTL with recurrent parent genome recovery rates ranging from 66.5% to 99.8%. Evaluation of the introgression rice lines grown in South Korea under low inputs of P and water revealed early vegetative growth advantage relative to that of the recurrent parents. Under rainfed condition, Pup1 introgression lines had yield advantage ranging from 7.2 to 19.9% and 24 to 26% in P non-supplied soil and P-supplied soil, respectively compared to that of the recurrent parents suggesting that Pup1 confers enhanced yield under low P and water inputs in temperate rice genetic background grown in temperate climate. In terms of early vegetative growth, temperate Pup1 introgression lines showed a similar trend on the extent to which Pup1 promotes yield advantage in temperate rice in comparison with indica control Pup1 introgression line IR64-Pup1.

• 한국산업보건학회지
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• 제20권3호
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• pp.184-191
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• 2010

Although the usage of nanomaterials including carbon nanotubes (CNTs) has increased in various fields, scientific researches on workers' exposures and controls of these materials are very limited. The purpose of this study was to compare the airborne nanoparticles concentrations from two university laboratories conducting experiments of CNTs growth based on containment of thermal chemical vapor deposition (CVD). Airborne nanoparticle concentrations in three metrics (surface area concentration, particle number concentration, and mass concentrations) were measured by task using three direct reading instruments. In a laboratory where CVD was not contained, the surface area concentration, number concentration and mass(PM$_1$) concentration of airborne nanoparticles were 1.5 to 3.5 times higher than those in the other laboratory where CVD was confined. The ratio of PM$_1$ concentration to total suspended particles(TSP) in the laboratory where CVD was not confined was about 4 times higher than that in the other laboratory. This indicates that CVD is a major source of airbone nanoparticles in the CNTs growth laboratories. In conclusion, researchers performing CNTs growth experiments in these laboratories were exposed to airborne nanoparticles levels higher than background levels, and their exposures in a laboratory with the unconfined CVD were higher than those in the other laboratory with the confined CVD. It is recommended that in the CNTs growth laboratories adequate controls including containment of CVD be implemented for minimizing researchers' exposures to airborne nanoparticles.