• Current Research on Agriculture and Life Sciences
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• v.1
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• pp.113-140
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• 1983

This is a study on a landscape planning along the street 1~4, which are gateways to Taegu city and an important scenery. Therefore, emphasis was given to provide a bright, clean and beautiful first impression to visitors and citizens. The area is being developed for education and athletic park. Plans to construct a fountain, pergolas and a pond were set up to complement the active and passive facilities to the existing a athletic facilities in the area. Since D part in the area have alkali soil (pH 8.1), soil amendment is necessary for successful growth of trees and ground covers. When the area is filled or added with new soil for soil amendment, it will be important to use fresh soil which can support plant growth. It will be ideal to use ground covers and shrubs on the existing retaining walls along the street for keeping natural vegetation and slope stability instead of further cutting and reconstruction. It is not reasonable in technical and economic sense to remove rocks of the slope for planting trees. In order to harmonize plant color distribute, tall needle and broad leaf trees in the background as a screen, flowering trees were arranged in groups at front, and annuals were mass-planted along the footway. Natural-form-trees will be planted because they not only serve as a greenbelt but also are more economics in maintenance than formative trees.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.16
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• pp.7031-7038
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• 2015

Background: Arginine may play important roles in tumor progression by providing ornithine for polyamine biosynthesis, required for cell growth. The aim of this work was to determine the expression of arginine metabolic pathway enzymes in head and neck squamous cell carcinoma (HNSCC) in northeast India. Materials and Methods: The expressions of arginase isoforms (ARG1 and ARG2), ornithine aminotransferase (OAT) and ornithine decarboxylase (ODC) were examined in fifty paired HNSCC and adjacent non-tumor tissues by immunohistochemistry. Immunocytochemistry, semiquantitative reverse transcription sq-PCR and quantitative real-time qPCR were used to assess protein and mRNA expressions in peripheral blood of fifty HNSCC patients and hundred controls. Results: ARG1 and ODC protein and mRNA were strongly expressed in peripheral blood from HNSCC patients. No ARG2 expression was observed. In vivo, expression of ARG1, ARG2 and ODC was significantly higher in tumor than in non-tumor tissues. Most tumors expressed low levels of OAT, with no difference in tissues or blood, compared to controls. The absolute extent of maximal ARG1 upregulation with qPCR showed 6.23 fold increase in HNSCC. Conclusions: These findings strongly suggest that in HNSCCs, the ARG1 pathway is stimulated leading to the formation of polyamines as indicated by higher ODC expression, which promote tumor growth.

• Journal of the Korea Furniture Society
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• v.29 no.1
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• pp.31-39
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• 2018

Recently, as the continuously increasing of the one-person households, builders were focusing on a built-in furniture development for efficiency. Through the dead space of the space can be reduced. Also, Condensation that occurs in a built-in furnitures installation space may result in different results depending on the room's direction, floor, finish, adjacent room effect, occupant's lifestyle. In this background, it can be considered in terms of functional aspect and morphological aspect by using WUFI2D simulation system. As a result, the tendency of occurrence of condensation was examined by comparing the water content and the growth potential of fungus graph which came from WUFI2D. Results of this study are as followings: Built-in furniture, both top & bottom open, is more stable to condensation than the built-in furniture with the top or bottom open. Also, Among from the top floor built-in furniture to the bottom of it, the bottom one is more stable to condensation.

• Molecules and Cells
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• v.39 no.11
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• pp.827-833
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• 2016

Regulator of calcineurin 1 (RCAN1) binds to calcineurin through the PxIxIT motif, which is evolutionarily conserved. SP repeat phosphorylation in RCAN1 is required for its complete function. The specific interaction between RCAN1 and calcineurin is critical for calcium/calmodulin-dependent regulation of calcineurin serine/threonine phosphatase activity. In this study, we investigated two available deletion rcan-1 mutants in Caenorhabditis elegans, which proceed differently for transcription and translation. We found that rcan-1 may be required for calcineurin activity and possess calcineurin-independent function in body growth and egg-laying behavior. In the genetic background of enhanced calcineurin activity, the rcan-1 mutant expressing a truncated RCAN-1 which retains the calcineurin-binding PxIxIT motif but misses SP repeats stimulated growth, while rcan-1 lack mutant resulted in hyperactive egg-laying suppression. These data suggest rcan-1 has unknown functions independent of calcineurin, and may be a stimulatory calcineurin regulator under certain circumstances.

• Nutrition Research and Practice
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• v.9 no.1
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• pp.17-21
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• 2015

BACKGROUND/OBJECTIVES: In this study, the inhibitory effect of Erythronium japonicum extracts on the metastasis of MDA-MB-231 human breast cancer cell line was determined. MATERIALS/METHODS: Cells were cultured with DMSO or with 50, 75, 100 or $250{\mu}g/ml$ of Erythronium japonicum methanol or ethanol extract. RESULTS: Both methanol and ethanol extracts significantly inhibited the growth and induced apoptosis of MDA-MB-231 cells in a dose-dependent manner. Erythronium japonicum extracts inhibited the adhesion of MDA-MB-231 cells. The invasion of breast cancer cells was suppressed by Erythronium japonicum extracts in a dose-dependent manner. The motility and MMP-2 and MMP-9 activities were also inhibited by both methanol and ethanol extracts. CONCLUSIONS: Our results collectively indicate that Erythronium japonicum extracts inhibit the growth, adhesion, migration and invasion as well as induce the apoptosis of human breast cancer cells. Clinical application of Erythronium japonicum as a potent chemopreventive agent may be helpful in limiting breast cancer invasion and metastasis.

• Journal of the Korean Society of Costume
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• v.18
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• pp.195-210
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• 1992

The present research analyzed the social meaning of Korean clothing in women's magazine. The data were included the advertisements and publicity related to Korean clothing in two women's magazines and condensed at 5 year intervals with content analysis. The identified 276 advertisements and publicity were categorized into four areas. The categories were the trend of exterior growth of advertisements and publicity, appeals and approach, the elements of advertisements and publicity including background, the relation of models, situations, and styles of Korean clothing over times. The results of the study were as Follows: 1. In conjunction with external growth of advertisements and publicity of Korean clothing, the social meaning of Korean clothing has changed from ceremonial clothing to daily-wear clothing. Especially since 1980, the theme of advertisement and publicity of Korean clothing were changed form the beauty of traditional Korean clothing such as grace of dignity to the individuality which was the typical value of western Clothing. 2. The trends of appeals related to Korean clothing and applied Korean clothing have reflected the changing time and society. Since 1980, the emotional or mixed approach with metaphor have increased, whereas factual or situational approach were dominated in 1960s and 1970s. 3. The styles including silhouette, detail, textile and pattern of Korean clothing and applied Korean clothing also reflected the changing trends of Korean society. Especially since 1980, the applied style of Korean clothing has adopted the trends of western clothing. Implications for the future research were suggested.

• Korean Journal of Environmental Agriculture
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• v.35 no.2
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• pp.148-151
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• 2016

BACKGROUND: There are few studies on the impacts of hydrophytes on water quality, so there is a need to research the effects of death of hydrophytes on the worsening of water quality. This study aimed to monitor the effects of Trapa japonica death on reservoir water quality.METHODS AND RESULTS: T.japonica shows the life cycle that highest growth in summer and rapid death in fall decomposing their body in general. T.japonica contains comparatively large portion of nutrients and minerals. Through the field survey using Mesocosm to identify the effects of excessive population of T.japonica on water quality, the water quality of plots planted T.japonica is gradually worse compared with the control plot. And the result of Wilcoxon-test also shows that the negative effect of T.japonica on water quality with significant (p<0.05).CONCLUSION: It is necessary to control the population growth of T.japonica in order to prevention of water pollution in fall.

• Health Policy and Management
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• v.14 no.4
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• pp.21-47
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• 2004

There is general agreement that the Korean health care delivery system has two basic structural problems. One is the limited capacity and role of public hospitals, and the other is the absence of functional differentiation and referral arrangement between the clinics and hospitals of various technological sophistication levels. This study is intended to make an empirical observation of the system's growth process from the viewpoint of the population ecology model of organizations so as to understand the background of these problems and to find out ways of approaching them. As predicted from the population ecology model of organizations, all the types of medical care facilities have expanded in response to the environmental changes for the past three decades or so, and the differences in the extent and pattern of expansion among the types are related to what have taken place in the environment. These findings suggest that the efforts for reforming the health care delivery system should be directed not only to medical care institutions but also to the environmental context under which they function. It is believed that the usefulness of the population ecology perspective on organizations for studying the health care delivery system has been demonstrated. Thus further studies along this line based upon more strict design would improve systematic understanding of the system that is needed for developing policy approaches needed to increase its effectiveness.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7601-7605
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• 2013

Background: Gambogenic acid is a major active compound of gamboge which exudes from the Garcinia hanburyi tree. Gambogenic acid anti-cancer activity in vitro has been reported in several studies, including an A549 nude mouse model. However, the mechanisms of action remain unclear. Methods: We used nude mouse models to detect the effect of gambogenic acid on breast tumors, analyzing expression of apoptosis-related proteins in vivo by Western blotting. Effects on cell proliferation, apoptosis and apoptosis-related proteins in MDA-MB-231 cells were detected by MTT, flow cytometry and Western blotting. Inhibitors of caspase-3,-8,-9 were also used to detect effects on caspase family members. Results: We found that gambogenic acid suppressed breast tumor growth in vivo, in association with increased expression of Fas and cleaved caspase-3,-8,-9 and bax, as well as decrease in the anti-apoptotic protein bcl-2. Gambogenic acid inhibited cell proliferation and induced cell apoptosis in a concentration-dependent manner. Conclusion: Our observations suggested that Gambogenic acid suppressed breast cancer MDA-MB-231 cell growth by mediating apoptosis through death receptor and mitochondrial pathways in vivo and in vitro.

• Journal of the Ergonomics Society of Korea
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• v.33 no.5
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• pp.337-354
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• 2014

Objective: The purpose of this study was to examine the various sizing systems and specified anthropometric data as well as the fit issues used today. Background: A standard sizing system for clothes is a system that is developed based on body shape and size classifications method. To develop an efficient sizing system, we have to classify the database from the majority of the samples. Method: The method of this paper deals with the secular trend of height spanning from 1997 to 2010 along with the morphological feature patterns for Koreans. It also investigates the comparison of the growth pattern between male and female and the body shape classification according to the drop values based on the anthropometric data samples of KATS taken from the 2010 surveys in order to develop and define the new guidelines for the size designation systems of clothes. Results: The results are classified with body size and shape categories according to the drop values by age and sex in order to develop the new guidelines for the size designation systems based on these body dimensions from the analyzed anthropometric database. Conclusion: These new guidelines for the size designation system will eliminate the confusion that currently exists among countries and individual apparel designers. Application: The adopted standards could be used to compare the sizing systems worldwide.