Gambogenic Acid Induction of Apoptosis in a Breast Cancer Cell Line |
Zhou, Jing
(Department of Clinical Medicine, Taizhou People's Hospital)
Luo, Yan-Hong (Department of Oncology, Jiangsu Cancer Hospital) Wang, Ji-Rong (Department of Oncology, Second Affiliated Hospital of Nanjing Medical University) Lu, Bin-Bin (Department of Oncology, Second Affiliated Hospital of Nanjing Medical University) Wang, Ke-Ming (Department of Oncology, Second Affiliated Hospital of Nanjing Medical University) Tian, Ye (Department of Clinical Medicine, Taizhou People's Hospital) |
1 | Chen HB, Zhou LZ, Mei L,et al (2012). Gambogenic acidinduced time- and dose-dependent growth inhibition and apoptosis involving Akt pathway inactivation in U251 glioblastoma cells. J Nat Med, 66, 62-9. DOI ScienceOn |
2 | Hu C, Huang L, Gest C, et al (2012). Opposite regulation by PI3K/Akt and MAPK/ERK pathways of tissue factor expression, cell-associated procoagulant activity and invasiveness in MDA-MB-231 cells. J Hematol Oncol, 5, 16-35. DOI |
3 | Jing GJ, Wang JJ, Zhang SX (2012). ER stress and apoptosis: a new mechanism for retinal cell death. Exp Diabetes Res, 11, 589589. |
4 | Kerr JF, Wyllie AH, Currie AR (1972). Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer, 26, 239-57. DOI ScienceOn |
5 | Kane DJ, Sarafian TA, Anton R, et al (1993). Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science, 262, 1274-7. DOI |
6 | Kojima Y, Tsurumi H, Goto N, et al (2006). Fas and Fas ligand expression on germinal center typediffuse large B-cell lymphoma is associated with the clinical outcome. Eur J Haematol,76,465-72. DOI ScienceOn |
7 | Lu GB, Yang XX, Huang QS (1984). Isolation and structure of neo-gambogic acid from Gamboge (Garcinia hanburryi). Yao Xue Xue Bao 1984, 19, 636-9. |
8 | Lei M, Liu JM, Chin J (2003). Cancer Prevent. Treat, 10, 216-9. |
9 | Li QL, Cheng H, Zhou A, et al (2010). Gambogenic Acid Inhibits Proliferration of A549 Cells through Apoptosis-Inducing and Cell Cycle Arresting. Biol Pharm Bull, 33, 415-20. DOI ScienceOn |
10 | Lin SX, Chen J, Mazumdar M, et al (2010). Molecular therapy of breast cancer: progress and future directions. Nat Rev Endocrinol, 6, 485-93. DOI ScienceOn |
11 | Niu G, Yin S, Xie S, et al (2011). Quercetin induces apoptosis by activating caspase-3 and regulating Bcl-2 and cyclooxygenase-2 pathways in human HL-60 cells. Acta Biochim Biophys Sin (Shanghai), 43, 30-7. DOI ScienceOn |
12 | Panthong A, Norkaew P, Kanjanapothi D, et al (2008). Antiinflammatory, analgesic and antipyretic activities of the extract of gamboge from Garcinia hanburyi Hook f. J Ethnopharmacol, 111, 335-40. |
13 | Perez EA (2009). Impact, mechanisms, and novel chemotherapy strategies for overcoming resistance to anthracyclines and taxanes in metastatic breast cancer. Breast Cancer Research and Treatment, 114, 195-201. DOI |
14 | Park JB, Lee JK, Park EY, Riew KD (2008). Fas/FasL interaction of nucleus pulposus and cancer cells with the activation of caspases. Int Orthop, 32, 835-40. DOI |
15 | Spierings D, Mcstay G, Saleh M, et al (2005). Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis. Science, 310, 66-7. DOI ScienceOn |
16 | Tan W, Lu JJ, Huang MQ, et al (2011). Anti-cancer natural products isolated from Chinese medical herbs. Chinese Medicine, 6, 27-41. DOI ScienceOn |
17 | Yan FG, Wang M, Chen H, et al (2011). Gambogenic acid mediated apoptosis through the mitochondrial oxidative stress and inactivation of Akt signaling pathway in human nasopharyngeal carcinoma CNE-1 cells. Eur J Pharmacol, 652, 23-32. DOI ScienceOn |
18 | Tomas NM, Masur K, Piecha JC, Niggemann B, Zanker KS (2012). Akt and phospholipase Cgamma are involved in the regulation of growth and migration of MDA-MB-468 breast cancer and SW480 colon cancer cells when cultured with diabetogenic levels of glucose and insulin. BMC Res Notes, 5, 214-28. DOI |
19 | Wang KM, Tang YH, Sun M, et al (2011). The mechanism of neogambogic acid-induced apoptosis in human MCF-7 cells. Acta Biochim Biophys Sin, 43, 698-702. DOI ScienceOn |
20 | Wang H, Sha W, Liu Z, Chi CW (2011). Effect of chymotrypsin C and related proteins on ancreatic cancer cell migration. Acta Biochim Biophys sin (Shanghai), 43, 362-71. DOI ScienceOn |
21 | Yan FG, Wang M, Li JM, et al (2012). Gambogenic acid induced mitochondrial-dependent apoptosis and referred to Phospho-Erk1/2 and Phospho-p38 MAPK in human hepatoma HepG2 cells. Environ Toxicol Pharmacol, 33, 181-90. DOI ScienceOn |
22 | Zhai DY, Jin CF, Shiau CW, et al (2008). Gambogic acid is an antagonist of antiapoptotic Bcl-2 family Proteins. Mol Cancer Ther, 7, 1639-46. DOI ScienceOn |
23 | Zhou A, Li QL, Peng DY, et al (2008). Determination of the content of gambogic acid and gambogenic acid in gamboge by HPLC. J Sep Sci, 15, 53-4. |
24 | American Cancer Society (2011). Learn about Cancer-Breast Cancer. 2011. Available online:http://www.cancer.org/Cancer/BreastCancer/DetailedGuide/ breast-cancer-keystatistics (accessed on 25 May 2011). |