• Journal of Veterinary Clinics
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• v.21 no.4
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• pp.374-397
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• 2004

This experiment was designed to investigate the analgesic effect of non-invasive electroacupuncture treatment on femoral head osteotomy in dogs. Twelve dogs were divided into 3 groups in this experiment. Electroacupuncture group was non-invasively electrostimulated in Huan Tiao (GB-30) acupoint for 10 minutes by 4.5V, 5Hz for 10 days. Medication group was treated with carprofen (4mg/kg, P.O.) for 10 days. Control group was not treated. Each group was pre-operatively and post-operatively scored by using VAS (Visual Analogue Scale), SDS (Simple Descriptive Scale), NRS (Numerical Rating Scale), and measured serum cortisol levels. The results of VAS, SDS and NRS in electroacupuncture and medication groups were better than those of control group. And, the results of electroacupuncture group were better than those of medication group since 6th day after osteotomy in pain management(p<0.05). But, there were no significances in serum cortisol level among 3 groups. In conclusion, non-invasive electroacupuncture treatment showed sufficient analgesic effect on postoperative pain management after femoral head osteotomy, and VAS, SDS, and NRS scoring system would be adapted in evaluation of pain management.

• Journal of Korean Elementary Science Education
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• v.20 no.2
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• pp.271-280
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• 2001

The purpose of this study is to investigate how free inquiry activities affects the scientific process skills and scientific attitudes of 5th and 6th of elementary school students. For this study, 265 elementary students from 5th and 6th grade in Seoul were selected. In comparison group 130 students were implemented and to the experimental group 135 students who did not the free inquiry activities were implemented. The result of this study is as follows: First, curiosity was the most affective factor that motivate free inquiry activities and made them select their topics. Most of the students invested for the inquiry activity in less than 3 weeks. They had some help in every stages. Students became interested in free inquiry activities because they learned new facts and enjoyed doing experiments and they wanted to continue for the same reasons. Second, free inquiry activities had little effect on the basic science process skills of the experimental group, compared to the control group at the significant difference of p=0.05. Third, free inquiry activities had considerable effect on the integrative inquiry process skills of the experimental group, compared to the control group at the significant difference of p=0.05. Fourth, the result of the post-test of the experimental group showed that free inquiry activities had no effect on scientific attitudes at the significant difference of p=0.05. In conclusion, free inquiry activities will be much more effective in developing integrative inquiry process skills than in developing basic scientific process skills and scientific attitudes.

• Journal of People, Plants, and Environment
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• v.23 no.3
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• pp.363-375
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• 2020

Background and objective: Recreation or activities in forest are regarded as therapy. Many forest therapy programs have been developed and assessed in the domestic. This study was conducted to investigate the effect of the forest therapy program on academic and job-seeking stress in college students. Methods: Thirty five subjects were selected as the experimental group and 25 as the control group, and 29 subjects in the experimental group and 11 in the control group participated in the follow-up test to verify the persistence of stress reduction effects. The forest therapy program was carried out once a week for 2 hours each from September 4 to December 4, 2018, adding up to total eight sessions. Results: The experimental group showed statistically significant reduction in both academic stress and job-seeking stress, whereas the control group did not. For the persistence of the forest therapy program, the experimental group did not show a statistically significant difference between the posttest and the follow-up test, and thus the stress reduction effect was maintained. Conclusion: This study proved the reduction of academic and job-seeking stress in forest therapy programs and the persistence of the stress reduction effect of the forest therapy program. The result is consistent with the Stress Recovery Theory (SRT) that shows the stress reduction effect of nature. In addition, it has significance in that it has verified that the program using the forest on campus can reduce stress of most college students.

• Journal of Ginseng Research
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• v.18 no.3
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• pp.151-159
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• 1994

To evaluate the anticarcinogenic effect and its mechanism of red ginseng, the mice were treated with red ginseng and received subcutaneous Bl6 melanoma cell line injection on the back. Tumor incidence was same (100%) both in water and red ginseng-treated groups, but tumor production was delayed in red ginseng-treated group. Survival time was somewhat longer in red ginseng-treated group. The histopathological findings were similar in both groups, but lymphocytic infiltration around the tumor and melanin production in the tumor cells were prominent in the red ginseng-treated group. Flow cytometric analysis on T lymphocytes and natural killer cells revealed increased $T_H$/$T_S$ ratio and increased NK cells in red ginseng-treated group. These results suggest that the anticarcinogenic effect of red ginseng may be exerted by the increased cell-mediated immunity and natural killer cell activity.

• Journal of Korean Academy of Nursing
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• v.34 no.7
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• pp.1362-1371
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• 2004

Purpose: This study was to examine the effect of an obesity management program on the body weight, body-mass index, and physiological index of obese female high school students. Method: Students from one school were selected as the experimental group, and students from another school as a control group so the latter group wasn't exposed to the experiment. The experimental group and the control group were each organized with 20 students. The experimental group received 60 minutes of behavior modification once a week, for eight weeks. Result: The Body weight, and Body mass-Index of the experimental group significantly decreased after the obesity management program. Total-cholesterol, T-G, and LDL-C significantly decreased and HDL-C increased in the experimental group. Total-cholesterol, T-G, LDL-C and HDL-C between the experimental group and control group showed significant differences. Conclusion: These results indicate that the obesity management program had a great effect on decreasing the body weight and body-mass index of the female obese high school students, normalizing their physiological index. In conclusion, this program turned out to be one of the safest and most effective obesity-management methods that could be applied to female high school students.

• English Language & Literature Teaching
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• v.10 no.2
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• pp.89-111
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• 2004

The purpose of this article is to study the effect of finger play teaching method on the reproduction of children's English words. The hypotheses are as follows: 1) there will be the difference of the reproduction of children's English words between the experimental group(that is taught by finger play teaching method) and the controlled group (that is taught by only oral teaching method). 2) there will be the difference of children's retention capacity of reproducing English words between the experimental group and the controlled group, The researcher made the time series data The measure tool was the check list for reproduction test of children's English words that was made by Run-Soon Oh and J. Eden(2004). The researcher analyzed the data using the Repeated Measures ANOVA and the Analysis of Covariance. The findings of research are as follows: 1) the more the frequency of teaching increases, the more there are the difference of reproducing English words according to frequencies and groups. The reproduction capacity of the experimental group is better than that of the controlled group. A degree of statistical significance is p<.001. 2) The difference of retention capacity of reproducing English words between the experimental group and the controlled group is a statistical significant, p<.05. The experimental group is better than the controlled group.

• International Journal of Oral Biology
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• v.41 no.2
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• pp.63-68
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• 2016

The aim of this study was to investigate the effect of n-3 polyunsaturated fatty acids (PUFAs) on eruptive movement during tooth development. Sprague-Dawley (SD) rat pups were randomly divided into two groups; control group and experimental group. The experimental group was administered daily with n-3 PUFA by intraperitoneal (IP) injection. After 10 days postpartum, rat pups were sacrificed to evaluate the effect of n-3 PUFA on eruptive tooth movement. Histological analyses were by hematoxylin-eosin (H&E) staining. Tartrate-resistant acid phosphatase (TRAP) assay was performed to compare the osteoclast distribution in the bone matrix above the developing molar teeth. Incisor teeth eruptions were noticeably observed in IP group, as compared to control group. Rat pups in IP group showed faster tooth eruption on day 8 after birth. Through histological analyses, IP group showed thinner bone matrix and more osteoclasts above the $1^{st}$ molar teeth, as compared to control group. TRAP assay showed significantly stronger stained pattern that the osteoclast above the $1^{st}$ molar teeth in IP group, as compared to control group. The results suggested that n-3 PUFA could affect osteoclastic activity involved in bony remodeling during eruptive tooth movement.

• The Journal of Korean Physical Therapy
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• v.19 no.4
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• pp.33-41
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• 2007

Purpose: To investigate environmental enrichment and nerve stimulation follows in application times with the change of BDNF & Trk-B receptor in the motor cortex and spinal cord. Methods: Experimental groups were divided into the five groups. Group I: normal control group, Group II: experiment control group, Group III: sciatic never electrical stimulation after MCAO, Group IV: application of only environmental enrichment after MCAO, Group V: never electrical stimulation with environmental enrichment after MCAO. Histologic observation and coronal sections were processed individually in goat polyclonal antibody phosphorylated BDNF and rabbit polyclonal antibody Trk-B receptor. Results: In immunohistochemistric response of BDNF and Trk-B, group II were showed that lower response effect at postischemic 1 days, 3 days, and 7 days. Group V were showed that increase response effect at postischemic 3 days, 7 days and 14 days. Specially showed that the most response effect at postischemic 14 days. In neurobehavioral assessment, group V were significantly difference from other groups on between-subject effects. Conclusion: The above results suggest that combined environmental enrichment with peripheral nerve electrical stimulation in focal ischemic brain injury were more improved that the change of BDNF & Trk-B receptor expression than non treatment.

• Food Science of Animal Resources
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• v.44 no.1
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• pp.178-188
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• 2024

The aim of this study is to investigate whether milk fermented by Lactiplantibacillus plantarum K79, which exhibits angiotensin-converting enzyme inhibitory activity, has an effect on lowering the blood pressure of hypertensive rats and to investigate biomarker changes in their blood. Experimental group: normal group (NG, Wistar-Kyoto rats): distilled water, control group [NCG, spontaneously hypertensive rats (SHR)]: distilled water, high treatment group (HTG, SHR): 500 mg/kg/day, medium treatment group (SHR): 335 mg/kg/day, low treatment group (SHR): 170 mg/kg/day, positive control group (PCG, SHR): Enalapril, 10 mg/kg/day. The experimental animals used in this study were divided into groups composed of 8 animals. In terms of weight change, a significant difference was observed between the NG and the SHR group, but there was no significant difference between the SHR group. After 8 wk of feeding, blood pressure was lowered more significantly in the HTG (209.9±13.3 mmHg) than in the NCG (230.8±7.3 mmHg). The treatment group has an effect of lowering blood pressure by significantly suppressing blood pressure-related biomarker protein expression than NG. The results obtained can be used as an antihypertensive material in a variety of food raw materials.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.21 no.3
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• pp.10-19
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• 2008

Objective : To investigate the effects of Radix Ophiopogon japonieus on atopic dermatitis, I prepared DNCB(2,4-dinitrochlorobenzen) induced atopic dermatitis NC/Nga mice and observed the mice by four ways; eye observation, the number of skin behavior times, histological changes of skin and cytokine(Total IgE, IL-4, $IFN-{\gamma}$). Methods : After prepare Radix Ophiopogon japonicus extract, DNCB induced atopic dermatitis NC/Nga mice were divided into three groups. The first is Control group which was intact group. The second is Medication group which was orally medicated Radix Ophiopogon japonicus extract one time a day for consecutive 5 days. The third group is Application group which was applied Radix Ophiopogon japonicus extract externally one time a day for consecutive 5 days. After that, the effect of Radix Ophiopogon japonicus on atopic dermatitis was observed. Statistical analysis was performed by using Kmskal-Wallis test and statistical significance was set at less than 5%. Results : 1. Radix Ophiopogon japonicus showed some in both Medication group and Application At observation of skin morphologic change, effects to prevent erythema reaction on skin group. 2. At the number of scratching behavior times, Radix Ophiopogon japonicus showed an effect to decrease scratching behavior times, but there was no statistical significance among three groups. 3. At skin tissue H-E stain, Radix Ophiopogon japonicus showed an effect to prevent skin epidermal tissue damages and also showed that it could keep the skin healthy in both Medication group and Application group. Especially in Application group, the skin of mouse showed almost normal recovery. 4. At cytokines, there was no statistical significance among three groups in IgE and IL-4. But Radix Ophiopogon japonicus showed an significant effect to suppress $IFN-{\gamma}$ in both Medication group and Application group. There was no significant difference between two groups. Conclusion : Radix Ophiopogon japonicus has some effects on atopic dermatitis in both internal medication and external application.