• Title/Summary/Keyword: Group Model

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Novel nomogram-based integrated gonadotropin therapy individualization in in vitro fertilization/intracytoplasmic sperm injection: A modeling approach

  • Ebid, Abdel Hameed IM;Motaleb, Sara M Abdel;Mostafa, Mahmoud I;Soliman, Mahmoud MA
    • Clinical and Experimental Reproductive Medicine
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    • v.48 no.2
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    • pp.163-173
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    • 2021
  • Objective: This study aimed to characterize a validated model for predicting oocyte retrieval in controlled ovarian stimulation (COS) and to construct model-based nomograms for assistance in clinical decision-making regarding the gonadotropin protocol and dose. Methods: This observational, retrospective, cohort study included 636 women with primary unexplained infertility and a normal menstrual cycle who were attempting assisted reproductive therapy for the first time. The enrolled women were split into an index group (n=497) for model building and a validation group (n=139). The primary outcome was absolute oocyte count. The dose-response relationship was tested using modified Poisson, negative binomial, hybrid Poisson-Emax, and linear models. The validation group was similarly analyzed, and its results were compared to that of the index group. Results: The Poisson model with the log-link function demonstrated superior predictive performance and precision (Akaike information criterion, 2,704; λ=8.27; relative standard error (λ)=2.02%). The covariate analysis included women's age (p<0.001), antral follicle count (p<0.001), basal follicle-stimulating hormone level (p<0.001), gonadotropin dose (p=0.042), and protocol type (p=0.002 and p<0.001 for short and antagonist protocols, respectively). The estimates from 500 bootstrap samples were close to those of the original model. The validation group showed model assessment metrics comparable to the index model. Based on the fitted model, a static nomogram was built to improve visualization. In addition, a dynamic electronic tool was created for convenience of use. Conclusion: Based on our validated model, nomograms were constructed to help clinicians individualize the stimulation protocol and gonadotropin doses in COS cycles.

An Analysis of Effect on the Application of the Structured and Unstructured Instruction Model for Environmental Problem Solving (환경 문제 해결을 위한 구조화된 수업 모형과 비구조화된 수업 모형의 적용 효과 분석)

  • Lee, Hyang-Mi;Choi, Don-Hyung
    • Hwankyungkyoyuk
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    • v.20 no.2
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    • pp.1-15
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    • 2007
  • The Environmental problem solving model is an instructional strategy to accomplish the aim of environmental education through investigation of environmental problems and issues of the community. This study is intended to compare the instructional effect of the structured model with the unstructured model of environmental problem solving. The experimental group received the structured instruction and the control group received the unstructured instruction. There did not appear to be any significant difference between the groups in regard to knowledge but in regard to knowledge of environmental issues, the experimental group was more effective than the control group. No significant differences existed between the groups in attitude. In regard to investigating skill and evaluation of environmental issues, the experimental group was significantly more effective than the control group. The experimental group was significantly more effective than the control group in regard to environmental action skills. To foster responsible environmental behavior, environmental education a number of methodologies must be considered and learners must be trained to become problem-solving citizens. It was noted that the structured instruction was more effective than the unstructured instruction in middle school where environmental issues were not taught as an independent subject. We conclude that environmental education must be systematically constructed and taught in a manner which takes into account both its goals and the characteristics of the various learners. We conclude that environmental education must be systematically constructed and taught in a manner which takes into account both its internal goals and the situations within which various types of learners explore environmental issues and solutions.

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Provably Secure Tree-Based Centralized Group Key Distribution: Security Model and Modular Approach (증명 가능한 트리기반 중앙 분배 방식의 그룹키 기법: 안전성 모델 및 변환모듈)

  • Kim Hyun-Jeong;Lee Su-Mi;Lee Dong Hoon
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.14 no.6
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    • pp.69-78
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    • 2004
  • During the last decade, security models have been defined for two- and three-parity key exchange protocols. Currently there is a growing research interest in security models for group key management schemes. While various security models and provably secure protocols have been proposed for distributed group key exchange schemes, no results are hewn for centralized group key distribution schemes in spite of their theoretical and practical importance. We describe security requirements and a formal security model for centralized group key distribution scheme: we define the model on the channel controlled by adversaries with the ability of strong user corruption. In the security model, we propose a conversion module which can transform centralized tree-based group key distribution schemes in the literature to provably secure centralized tree-based group key distribution schemes.

The Effects of tDCS and Montoya Stair Task on Sensorimotor Recovery and GFAP Expression in MCAo induced Stroke Rat Model

  • Sim, Ki-Cheol;Kim, Gi-Do;Kim, Kyung-Yoon;An, Ho-Jung;Lee, Joon-Hee;Min, Kyoung-Ok;Kim, Gye-Yeop
    • Journal of International Academy of Physical Therapy Research
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    • v.2 no.1
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    • pp.193-200
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    • 2011
  • This study is intended to examine the tDCS and Montoya stair task(MST) on sensorimotor recovery and glial scar expression in MCAo induced stroke model of rat. To achieve this goal, this study selected 80 SD rats of 8 weeks. The experiment groups were divided them into four groups, and assigned 20 rats to each group. Group I was a experimental control group; GroupII was a tDCS application group after MCAo; Group III was a MST application group after MCAo; Group IV was a tDCS and MST application group after MCAo. In each group, neurological function test measurement, motor behavior test, montoya stair task test, immunohistochemistric finding of GFAP expression finding were analyzed. In motor behavior test, the outcome of group I was significantly difference than the other group, especially from 14days. In montoya stair task test, the outcome of group I was significantly lower than the other group especially, group II were significantly different on 14days and group IV was most significantly difference than the other group. In immunohistochemistric finding, group II, III, IV were decrease GFAP expression on depend on time stream. These results throughout the MCAo due to focal ischemic brain injury rat model four weeks tDCS and MST was applied, when the neurobehavioural, upper extremity function and ability, histopathologic data suggest that sensorimotor function recovery and a positive influence on glial scar decrease and confirmed that.

Physical model test of Jintan underground gas storage cavern group

  • Chen, Yulong;Wei, Jiong
    • Geomechanics and Engineering
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    • v.30 no.1
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    • pp.45-49
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    • 2022
  • In the present study, a physical model was built for the Jintan underground gas storage cavern group according to the similarity theory. In this regard, four ellipsoid caverns were built with scaled in-situ stresses and internal pressure. Then the stability of underground caverns was analyzed. The obtained results demonstrate that loss of internal pressure adversely affects the safety of caverns and attention should be paid during the operation of gas storage.

The Effects of Simulation Training With Hybrid Model for Nursing Students on Nursing Performance Ability and Self Confidence (하이브리드모델 활용 시뮬레이션 교육이 간호학생의 간호수행능력과 자신감에 미치는 효과)

  • Lee, Suk Jeong;Park, Young Mi;Noh, Sang Mi
    • Korean Journal of Adult Nursing
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    • v.25 no.2
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    • pp.170-182
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    • 2013
  • Purpose: This study investigated the effectiveness of simulation training with a hybrid model of student nurses' performance ability and reported self confidence. Methods: A nonequivalent control group with pre-posttest was designed. Data collection was done during the first semester in 2012 at a college of nursing in Seoul. Nursing performance ability and reported self confidence related to taking care of patients with urinary problems were evaluated. The treatment group (n=96) received simulation training of a catheterization procedure with a hybrid model involving standardized patients and a mannequin. Nursing students in the comparison group (n=84) did not receive the simulation training but would receive it prior to their next clinical practicum's. Results: The treatment group showed a significantly higher performance ability and reported self confidence than that of the comparison group. The perceived helpfulness and contentment of the simulation training in experimental group was high. Conclusion: The findings of this study demonstrated that simulation with a hybrid model was effective in teaching skills prior to the clinical experience which suggests that skill development is not dependent on the actual clinical situation. Nurse educators should consider simulation training as a tool beyond that of clinical practicum.

Animal Model of LPRD (Laryngopharyngeal Reflux Disease) (인후두 위산 역류증의 동물 모형의 개발)

  • 김진국;김현준;이민우;남태욱;최홍식
    • Korean Journal of Bronchoesophagology
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    • v.7 no.1
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    • pp.5-8
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    • 2001
  • Background and Objectives: Complications arising from endotracheal intubation are uncommon but, when they do occur, can be significant. Placement of an endotracheal tube frequently results in trauma to the underlying laryngeal and tracheal tissue, although the trauma is usually reversible. Occasionally, these changes can be of a more permanent nature and result in severe impairment of the airway and/or voice. It is proposed that a common factor-gastroesophageal reflux-might be responsible. This study was performed in order to develop the animal model of LPRD using rats and investigated that LPRD could produce significant damage to larynx especially vocal cords. Materials and Methods : The each four rats were used in the experiment and control study. Each was anesthetized and larynx was exposed and injured in the unilateral aritenoid. Injured site was contact with normal saline(control group) and synthetic gastric juice(experimental group). The larynx was examined after 7days in normal environment. Results : All was survived in the control group and two was survived in the experimental group. In the control group, some inflammation cells was found but in the experimental group, granulation was found. Conclusion : We developed animal model of LPRD using rat and thought LPRD may Play an important role in the development of permanent laryngeal injury.

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A Study on Gap between Government's Institutions and Public People based on Ontology Inference about ICT Future Technology

  • Kim, Su-kyoung;Kim, Sung-en;Cho, Ill-gu;Ahn, Kee-hong
    • International Journal of Contents
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    • v.13 no.4
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    • pp.47-62
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    • 2017
  • This paper analyzes how much the gap existed between the public group and expert group using future issues and future core technologies that are announced in government institutions based on ontology. We calculated gap with two groups' point of view, one is expert groups' ideas that are based on future hopeful technologies documents, and another is public people ideas that are based on documents of contest that is hosted by 'Ministry of Science, ICT and Future Planning (MSIP)', and 'Institute for Information & communications Technology Promotion (IITP)'. For calculating these, we suggested SDGM model. In the case of ETRI Meta-trend ICT Field, there is a little gap between expert group and public group, and another case that is XT (ETRI determined future technologies excluding ICT field) Field, the gap is increasing annually. Moreover, in the case of all ETRI Meta trend, the gap is bigger than ICT and XT field. We analyzed, also, KEIT's future issues for generalizing this model. The gap existed between two groups. Utilizing SDGM model of this paper, people can interpret easily how much the gap exists between future technologies and issues that are announced in institutions.

A Study on the Wear comfort and the Wearing Effects of Maternity Girdles (시판 임산부용 거들의 착용감 및 착용효과에 관한 연구)

  • 최혜선
    • Journal of the Korean Home Economics Association
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    • v.29 no.3
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    • pp.11-21
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    • 1991
  • The study has been intended to find out meaningful information about the development of a prototype of enhanced maternity girdle. The girdles of three different models which were available in the market have been carried out by three six-month pregnant women and three nine-month pregnant women. The results of the study are as follows. 1. All three girdles showed improved wear effects in order of model A, model B, model C. Body surface area measurement and two body surface angles of abdomen are significantly dicreased by wearing and type of girdles. It is presumed that the reasons of good wear effect of model A is low expansion rate of the material and tight fitness of the model. Model B is made of material whose expansion rate is higher than model A. Also abdominal part of the model B is bias cut which is considered to result better stretch and consequently lower wear effect. 2. For wear comfort, subjects preferred in order of model B, model C, and model A. All subjects feel more comfortable after wearing girdles 30 minutes than after wearing girdles 1 day. Comparing 2 subject groups, 6-month pregnant group feel more comfortable about wearing girdles than 9-month pregnant group. 3. The girdles are expanded as a whole in order of model B, model C and model A. Considering the expansion rate of some specific area of the girdles, abdominal area expands more than hip area which expands more than thigh area. The expansion rates of girdles worn to 6-month pregnant group are very low at all area, while the expansion rates of girdles worn to 9-month pregnant group are very high.

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A Comparative Study of Factors Influencing Software Piracy : Focused on Different Software User Groups (소프트웨어 사용자 집단에 따른 불법복제 의도에 미치는 요인 비교 연구)

  • Kim, Joong Han
    • Journal of Information Technology Services
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    • v.14 no.2
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    • pp.15-31
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    • 2015
  • Software piracy is widespread throughout the world. It has negative effects on the software industry and the intellectual property market. Despite various deterrent policies, the phenomenon has been getting severe. The current study investigated the antecedents of software piracy attitudes and intention. In order to identify factors and their relationship, a research model for illegal piracy behavior was developed and empirically examined through a path analysis using structural equation model. Also, this study employed a multiple group structural equation model to investigate differences in structural weights across PC software user group and smartphone application user group. It was revealed that perceived benefit, habit, social factor, self-efficacy had positive effect on attitude toward software piracy, whereas perceived risk had a decreasing influence on attitude. Relationships between piracy attitudes and intentions were significant as well. Furthermore, the cross validation between two groups showed the path coefficients of habit to attitude and attitude to intention were significantly different. Implications for research and practice are discussed.