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Automatic Nerve Activity to Physiologic Response in Adult With Psychiatric Disorder: A Systemic Review (성인 정신장애의 청각자극에 따른 생리학적 반응 측정에 대한 체계적 고찰)

  • Jung, Hye-Rim;Kim, Kyeong-Mi
    • The Journal of Korean Academy of Sensory Integration
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    • v.9 no.1
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    • pp.45-52
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    • 2011
  • Objective : The aim of this study was to provide the method to measure physiologic response using equipments and auditory stimulation, and the physiologic response features of adult psychiatric disorders through a systemic review. Methods : The systemic review was executed using PubMed. The key words for search were "auditory stimulation, auditory startle, electromyograph, skin conductance, heart rate, psychiatric disorder, anxiety disorder, schizophrenia, depression". 8 studies were used for data analysis, and all of levels of evidence were level II. The substances of the review were subject(population), auditory stimulation, measure equipments and physiologic response features of psychiatric disorder. Results : 1. The subjects for the studies were anxiety disorder(4) and schizophrenia(4). 2. Auditory stimulation was used in 8 studies and visual stimulation with auditory stimulation was used in 2 studies to induce physiologic response. 3. Every study used electromyograph, and skin conductance was used in 2 studies and heart rate was used in 2 studies with electromyograph to measure physiologic response. 4. The subjects for the studies, schizophrenia and anxiety disorder(PTSD, OCD) have different physiologic response features with the normal control group. Conclusion : All studies used simple tones as an auditory stimulation and electromyograph to measure physiologic response. Psychiatric disorders indicated larger response, shorter and delayed habituation. The objective and systematic study using physiologic measure to investigate the sensory feature of psychologic disorders.

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Thermal Behavior of Energy Pile Considering Ground Thermal Conductivity and Thermal Interference Between Piles (주변 지반의 열전도도를 고려한 PHC 에너지파일의 열 거동 및 파일 간 열 간섭 현상에 대한 수치해석 연구)

  • Go, Gyu Hyun;Yoon, Seok;Park, Do Won;Lee, Seung-Rae
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.33 no.6
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    • pp.2381-2391
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    • 2013
  • In general, ground's thermal properties, types of heat exchanger, operational method, thermal interference between piles can be considered as key factors which affect the thermal performance of energy pile. This study focused on the effect of these factors on the performance by a numerical model reflecting a real ground condition. Depending on the degree of saturation of ground, pile's heat transfer rate showed a maximum difference of three times, and the thermal resistance of pile made a maximum difference of 8.7%. As for the type of heat exchanger effects on thermal performance, thermal efficiency of 3U type energy pile had a higher value than those of W and U types. The periodic operation (8 hours operation, 16 hours pause) can preserve about 20% of heat efficiency compared to continuous operation, and hence it has an advantage of preventing the thermal accumulation phenomenon. Thermal interference effect in group piles may vary depending on the ground condition because the extent decreases as the ground condition varies from saturated to dry. The optimal separation distance that maintains the decreasing rate of heat efficiency less than 1% was suggested as 3.2D in U type, 3.6D in W type, and 3.7D in 3U type in a general ground condition.

The Direction of Nursing Management Domain for Nursing Personal Licensing Examination Board (간호사 국가시험 과목 통합을 위한 간호관리학 영역의 방향)

  • Kim, Mun-Shil;Chi, Sung-Ai;Park, Kwang-Ok;Kim, In-Sook;Park, Hyun-Tae
    • Journal of Korean Academy of Nursing Administration
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    • v.8 no.4
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    • pp.515-534
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    • 2002
  • Purpose : This study was to provide a meaningful framework for establishment of the direction of Nursing Management area to get ready for Nursing Personal Licensing Examination Board. Method : Using methodological and descriptive research method, the research process was as follows: a preliminary work list which was performed by New Nurse related to nursing management area was made of such key information as the domain of nursing management work, the element of that domain, and the detail work content, by means of a broad review of literature related to nursing management on Licensing Examination for the new nurse. After this preliminary work list sought to obtain examination, consensus, and modification of expert group in the nursing management field, research instrument which was the work list performed by new nurse within nursing management area was to developed. And next, it was to survey various of the importance and the frequency of that work performance by registered nurse, nurse manager, and the professors to take responsible of nursing management. Finally, the educational content for nursing management at the level of baccalaureate was proposed by various analyzing of research results. Results : The work list which was performed by new nurse related to nursing management area consisted of 9 domains, 24 elements, and 80 detail work contents. After it was examined into such various analysis as descriptive statistics, ANOVA, mean range, and so on, of the importance perception of the work and the frequency of work performance, the educational contents for baccalaureate in nursing management which consisted of total 65 contents made up of 18 core contents and 47 essential contents, which new nurses have to necessarily know and perform within the nursing management area. Conclusion : The results of this study will contribute to identifying the work list of new nurses performed in nursing management area and also proposing the educational contents that was taught at the level of baccalaureate in nursing management area based on doing actually in nursing unit.

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Evaluation of various cephalometric measurements to predict the prognosis of early Class III malocclusion treatment (III급 부정교합의 조기 치료 예후 예측를 위한 두부방사선 계측 변수의 평가)

  • Son, Myung-Ho;Chang, Young-Il
    • The korean journal of orthodontics
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    • v.34 no.3 s.104
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    • pp.205-218
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    • 2004
  • The aims of this study were to investigate the differences in the early craniofacial morphology of Class III malocclusions with good, fair and poor occlusal stability and to elucidate a key determinant for distinguishing the cases. Lateral cephalograms of 30 subjects with Class III malocclusion in the mixed dentition were analyzed at the start of treatment (mean age of $8.58\pm1.47$). All subjects were reevaluated after a mean period of $7.50\pm1.94$ years comprising active treatment and retention. At this time, the samples were divided into three groups: good (10 subjects), fair (10 subjects) and poor (10 subjects) occlusal stability groups. According to the results of ANOVA, there were significant morphological differences in the early stage among the good, fair and poor occlusat stability groups, especially in variables that represented the vertical skeletal relationships. As well, there were already more dental compensations in the poor occlusal stability group. Stepwise discriminant analysis on the measurements at the time of first observation identified only one predictive variable: AB to mandibular plane angle(AB-MP). With this discriminant function, $83.3\%$of the original grouped cases were correctly classified and the canonical correlation coefficient was 0.857. In conclusion, AB-MP can be a possible predictor for the eventual prognosis of early Class III treatment. If it is below 60, the prognosis of early Class III treatment is expected to be poor, while if it is above 65, a good prognosis is expected.

The ERCC1 C118T Polymorphism Predicts Clinical Outcomes of Colorectal Cancer Patients Receiving Oxaliplatin-Based Chemotherapy: a Meta-analysis Based on 22 Studies

  • Qian, Ying-Ying;Liu, Xin-You;Wu, Qian;Song, Xian;Chen, Xiao-Feng;Liu, Yi-Qian;Pei, Dong;Shen, Li-Zong;Shu, Yong-Qian
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.19
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    • pp.8383-8390
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    • 2014
  • Background: Although the predictive value of the excision repair cross-complementing group 1 (ERCC1) C118T polymorphism in clinical outcomes of patients with colorectal cancer (CRC) receiving oxaliplatin-based chemotherapy has been evaluated in numerous published studies, the conclusions are conflicting. Therefore, we performed the present meta-analysis to determine the precise role of the ERCC1 C118T polymorphism in this clinical situation and help optimize individual chemotherapy. Materials and Methods: A multiple search strategy was used to identify eligible studies. Pooled odds ratios (ORs) and their 95% confidence intervals (CIs) were used to estimate objective response and oxaliplatin-induced toxicity, with hazard ratios (HRs) with 95%CIs for progression-free survival (PFS) and overall survival (OS). Results: A total of 22 studies including 2,846 CRC patients were eligible in the analysis. Overall, no significant correlation was found between the ERCC1 C118T polymorphism and objective response to oxaliplatin-based chemotherapy, in all patients or in the Asian and Caucasian subgroups. However, the pooled analysis showed that the PFS and OS were significantly shorter in patients who carried T/T or T/C genotypes of ERCC1 C118T as compared to the C/C genotype. On stratified analysis by ethnicity, the ERCC1 118T allele was associated with a favorable prognosis in Caucasians (PFS, HR=0.58, 95%CI: 0.24-1.44; OS, HR=0.38, 95%CI: 0.22-0.64) but an unfavorable prognosis in Asians (PFS, HR=2.49, 95%CI: 1.87-3.33; OS, HR=2.63, 95%CI: 1.87-3.69) based on a dominant model. In addition, we failed to find a statistically significant impact of ERCC1 C118T polymorphism on oxaliplatin-induced toxicity. Conclusions: The ERCC1 C118T polymorphism may have prognostic value in patients with CRC undergoing oxaliplatin-based chemotherapy.

The Effect of SNS Information Attributes on Usability and Diffusion Intention -Moderating Effect of Market Mavenism. (SNS정보속성이 유용성지각과 확산의도에 미치는 영향 -마켓메이븐경향(Market Mavenism)의 조절효과-)

  • Kim, Sang-Jo;Jung, Seon-Mi
    • Management & Information Systems Review
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    • v.36 no.1
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    • pp.95-114
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    • 2017
  • The purpose of this study is to search information attributes suitable for SNS and to identify the influence of individuals or groups who contribute to the creation and diffusion of information in the SNS. The researchers extracted the accuracy, two-sided information, novelty, diversity, and experiential factors that influence the acceptance and diffusion of information in the SNS, and identified the relationships among the variables, the usefulness of information and the degree of information diffusion intention. And researchers studied market maven who play the key role in creating and diffusing SNS information. A total of 600 questionnaires were collected and 549 questionnaires were used to test the research hypothesis. The results of the study are as follows. Consumers considered information, which had accuracy, two-sided, and experiential attributes, as useful. But novelty or diversity information were regarded as unuseful because of motive to avoid ambiguity. In the Market Maven Group who have the ability to acquire and edit SNS information, however, there were weak or negative causality between experience and accuracy and information usability factors. but positive causality between novelty and diversity factors of information and usability.

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Lifting Work Process Optimization Method in High-rise Building Construction Through Improvement of CYCLONE Modeling Method (CYCLONE 모델링 기법 개선을 통한 초고층 공사의 자재 양중 작업 프로세스 최적화 연구)

  • Hawng, Doowon;Kwon, Okyung;Choi, Yoonki
    • Korean Journal of Construction Engineering and Management
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    • v.18 no.2
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    • pp.58-70
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    • 2017
  • The planning for material lifting operations is one of the key processes in high-rise building construction. Several previous studies have used rough calculations by referring to existing practices or establishing a target value for lifting cycle time or operating rate. Therefore, the purpose of this study is to propose a material lifting process optimization method for reducing the lifting cycle time and increasing the operating rate. In this study, we improve the cyclic operation network (CYCLONE) modeling method that considers the duration and zone information of each work task. This method can be used to hand over work tasks to another crew group in the work process. According to this methodology, this study optimizes the material lifting process, performs a sensitivity analysis, and evaluates the field applicability of the proposed material lifting process optimization method. Therefore, the optimized process was then applied to a high-rise building construction site. The lifting work process time and operating rate for the simulated as - is lifting process data, optimized process data, and field application result data were compared for each lifting height. From this comparison, the effectiveness of the optimization methodology was confirmed.

A Study on the oxidation characteristics of micro-algal bio diesel derived from Dunaliella tertiolecta LB999 (Dunaliella tertiolecta LB999 유래 바이오디젤의 산화특성 연구)

  • Lee, Don-Min;Lee, Mi-Eun;Ha, Jong-Han;Ryu, Jin-Young;Choi, Chang-Yong;Shim, Sang-Hyuk;Lim, Sang-Min;Lee, Choul-Gyun;Lee, Bong-Hee
    • Journal of Marine Bioscience and Biotechnology
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    • v.7 no.1
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    • pp.1-10
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    • 2015
  • Bio diesel has advantages to reduce GHG(Greenhouse Gas) compare with the fossil fuel by using oil comes from plant/animal sources and even waste such as used cook oil. The diversity of energy feeds brings the positive effects to secure the national energy mix. In this circumstance, micro-algae is one of the prospective source, though some technical barriers. We analyzed the bio diesel which was derived from Dunaliella tertiolecta LB999 through the BD100 quality specifications designated by the law. From that result, it is revealed that the oxidation stability is one of the properties to be improved. In order to find the reason for low oxidation stability, we analyzed the oxidation tendency of each FAME components through some methods(EN 14111, EN14112, EN16091). In this study, we could find the higher double bond FAME portion, the more oxidative property(C18:1${\ll}C18:3$) in bio diesel and main unsaturated FAME group is acted as the key component deciding the bio diesel's oxidation stability. It is proved experimentally that C18:3 FAME are oxidized easily under the modified accelerated oxidation test. We also figure out low molecular weight hydrocarbon and FAME were founded as a result of thermal degradation. Some alcohol and aldehydes were also made by FAME oxidation. In conclusion, it is necessary to find the way to improve the micro-algal bio diesel's oxidation stability.

Stakeholders' Opinion on the Desired Characteristics of Nursing School Graduates and Factors Concerning Nursing Curriculum Development in Thailand

  • Kittiboonthawal, Prapai;Siriwanij, Wareewan;Ubolwan, Kanyarat;Maneechot, Munthana
    • Asian Journal for Public Opinion Research
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    • v.5 no.4
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    • pp.319-345
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    • 2018
  • Effective higher educational management in undergraduate nursing programs is an important issue from the viewpoint of stakeholders. This qualitative research aimed to examine the characteristics of nursing students and curriculum development of undergraduate nursing education from the opinions of Boromarajonani College of Nursing Saraburi, Thailand stakeholders. The population included 4 groups: 1) the alumni who have graduated within the past 5 years and currently work in primary, secondary, and tertiary care units, 2) the supervisors and colleagues of the alumni, 3) nursing lecturers, and 4) the current nursing students. The respondents who are the alumni, nursing lecturers, and current nursing student were selected using a purposive sampling, for the supervisors and colleagues were selected using snowball techniques. Semi-structured interview questions were used for data collection. Group discussions were conducted until saturation on 55 key informants. The qualitative data was analyzed using content analysis. Results showed the viewpoints of stakeholders on the characteristics of future nurse graduates were comprised of four elements: knowledge that meets standards; essential skills for self-development and lifelong learning process; good morals and professional ethics in providing nursing care; and nurse competencies in teamwork, communication, language, research, management, IT, life skills, and global literacy. The viewpoints on the development of the nursing curriculum focus on four elements: the learner, teaching and learning, course content, and instructor tasks. For learners, the admission criteria should include a minimum not only of knowledge, but also positive attitude, science, and art skills, since the nursing profession is both a science and the art of caring. Teaching and learning elements should be authentic, including exposure to real situations, an integrated network, and activities that improve nursing care. Course content was comprised of an updated curriculum, humanized nursing care, student center, theory and practice with moral integration, case-based study, critical thinking, multidisciplinary work, and love for the nursing profession. Instructor tasks are to elicit student ideas, provide opportunities to learn, support infrastructure, support technology use, and extra-curricular activities to develop the competencies of nursing students. Recommendations were that the curriculum administration should review the selection process of student candidates and instructional management to achieve expected outcomes of nursing characteristics in the future. The nurse lecturer should provide authentic and integrated instruction, decrease lecturing, cultivate a lifelong learning process, and sustain the nursing characteristics.

Effects of Central Interleukin-1 on the Cardiovascular Response in Hemorrhaged Rats

  • Kang, Joon-Ho;Jang, Jae-Hee;Ahn, Dong-Kuk;Park, Jae-Sik
    • The Korean Journal of Physiology and Pharmacology
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    • v.8 no.2
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    • pp.89-94
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    • 2004
  • The arterial pressure is regulated by the nervous and humoral mechanisms. The neuronal regulation is mostly carried out by the autonomic nervous system through the rostral ventrolateral medulla (RVLM), a key area for the cardiovascular regulation, and the humoral regulation is mediated by a number of substances, including the angiotensin (Ang) II and vasopressin. Recent studies suggest that central interleukin-1 (IL-1) activates the sympathetic nervous system and produces hypertension. The present study was undertaken to elucidate whether IL-1 and Ang II interact in the regulation of cardiovascular responses to the stress of hemorrhage. Thus, Sprague-Dawley rats were anesthetized and both femoral arteries were cannulated for direct measurement of arterial pressure and heart rate (HR) and for inducing hemorrhage. A guide cannula was placed into the lateral ventricle for injection of IL-1 $(0.1,\;1,\;10,\;20\;ng/2\;{\mu}l)$ or Ang II $(600\;ng/10\;{\mu}l)$. A glass microelectrode was inserted into the RVLM to record the single unit spike potential. Barosensitive neurons were identified by an increased number of single unit spikes in RVLM following intravenous injection of nitroprusside. I.c.v. $IL-1\;{\beta}$ increased mean arterial pressure (MAP) in a dose-dependent fashion, but HR in a dose-independent pattern. The baroreceptor reflex sensitivity was not affected by i.c.v. $IL-1\;{\beta}$. Both i.c.v. $IL-1\;{\alpha}\;and\;{\beta}$ produced similar increase in MAP and HR. When hemorrhage was induced after i.c.v. injection of $IL-1\;{\beta}$, the magnitude of MAP fall was not different from the control. The $IL-1\;{\beta}$ group showed a smaller decrease in HR and a lower spike potential count in RVLM than the control. MAP fall in response to hemorrhage after i.c.v. injection of Ang II was not different from the control. When both IL-1 and Ang II were simultaneously injected i.c.v., however, MAP fall was significantly smaller than the control, and HR was increased rather than decreased. These data suggest that IL-1, a defense immune mediator, manifests a hypertensive action in the central nervous system and attenuates the hypotensive response to hemorrhage by interaction with Ang II.