• Bulletin of the Korean Chemical Society
• /
• v.34 no.7
• /
• pp.2117-2124
• /
• 2013

The binding properties and sequence selectivities of ${\Delta}{\Delta}$- and ${\Lambda}{\Lambda}-[{\mu}-Ru_2(phen)_4(bip)]^{4+}$ (bip = 4,4'-biphenylene (imidazo [4,4-f][1,10]phenanthroline) complexes with $poly[d(A-T)_2]$ and $poly[d(G-C)_2]$ were investigated using conventional spectroscopic methods. When bound to $poly[d(A-T)_2]$, a large positive circular dichroism (CD) spectrum was induced in absorption region of the bridging moiety for both the ${\Delta}{\Delta}$- and ${\Lambda}{\Lambda}-[{\mu}-Ru_2(phen)_4(bip)]^{4+}$ complexes, which suggested that the bridging moiety sits in the minor groove of the polynucleotide. As luminescence intensity increased, decay times became longer and complexes were well-protected from the negatively charged iodide quencher compared to that in the absence of $poly[d(A-T)_2]$. These luminescence measurements indicated that Ru(II) enantiomers were in a less polar environment compared to that in water and supported by minor groove binding. An angle of $45^{\circ}$ between the molecular plane of the bridging moiety of the ${\Delta}{\Delta}-[{\mu}-Ru_2(phen)_4(bip)]^{4+}$ complex and the local DNA helix axis calculated from reduced linear dichroism ($LD^r$) spectrum further supported the minor groove binding mode. In the case of ${\Lambda}{\Lambda}-[{\mu}-Ru_2(phen)_4(bip)]^{4+}$ complex, this angle was $55^{\circ}$, suggesting a tilt of DNA stem near the binding site and bridging moiety sit in the minor groove of the $poly[d(A-T)_2]$. In contrast, neither ${\Delta}{\Delta}$-nor ${\Lambda}{\Lambda}-[{\mu}-Ru_2(phen)_4(bip)]^{4+}$ complex produced significant CD or $LD^r$ signal in the absorption region of the bridging moiety. Luminescence measurements revealed that both the ${\Delta}{\Delta}$- and ${\Lambda}{\Lambda}-[{\mu}-Ru_2(phen)_4(bip)]^{4+}$ complexes were partially accessible to the $I^-$ quencher. Furthermore, decay times became shorter when bis-Ru(II) complexes bound to $poly[d(G-C)_2]$. These observations suggest that both the ${\Delta}{\Delta}$- and ${\Lambda}{\Lambda}-[{\mu}-Ru_2(phen)_4(bip)]^{4+}$ complexes bind at the surface of $poly[d(G-C)_2]$, probably electrostatically to phosphate group. The results indicate that ${\Delta}{\Delta}$- and ${\Lambda}{\Lambda}-[{\mu}-Ru_2(phen)_4(bip)]^{4+}$ are able to discriminate between AT and GC base pairs.

• The Journal of Korean Academy of Prosthodontics
• /
• v.54 no.4
• /
• pp.387-392
• /
• 2016

Purpose: The aim of this study was to investigate the effects of grooved abutments on abutment screw loosening. Materials and methods: This study was conducted to evaluate the abutment screw loosening after 6 months for 50 patients (51 implants) treated at the department of Prosthodontics in Yonsei University Dental Hospital from March, 2015 to July, 2015. A control group with non-grooved abutment consists of 30 implants, and an experimental group with grooved abutment consists of 21 implants. Astra, Straumann, Implantium, Osstem system were used in the study. The abutments with loose screws cases after a period of 6 months has been investigated, with two kinds of measurements: 1) measuring the additional rotational angle on abutment during placement with the same force, 2) measuring the PTV on bucco-cervical area of implant crown. All data collected has been analyzed by normality test followed by Mann-Whitney test using SPSS program. Results: No complications were reported after 6 months for the 51 implants. Abutment screw loose and crown fracture have not been seen in the study groups. The data collected from the two measurements showed no significant differences between the two groups with P-value 0.576 (average= control group: $7.35^{\circ}$, experimental group: $4.75^{\circ}$) for the additional rotational angle measurement and with P-value 0.767 for PTV. Conclusion: There are no significant differences between the grooved and non-grooved abutment in screw stability. However, further studies with long-term followups and larger group of patients is needed in order to investigate the effects of grooved abutment on screw stability.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2004.05a
• /
• pp.84-84
• /
• 2004

다단 냉간단조 공정에서는 결함이 없는 재료의 유동, 금형내부의 완전한 충만과 금형의 수명향상 등을 위하여 예비성형체의 설계가 중요시되고 있다. 특히 최근 제품의 정밀도에 관심이 집중되어 냉간 상태에서 완제품으로 성형하여 후속 기계가공을 없앰으로써 재료의 절약, 에너지 절감, 가공공정수 단축 등 냉간단조를 고부가가치 가공의 유력한 수단으로 응용하려는 추세이다. 이러한 경우 예비성형체의 형상은 제품의 정밀도와 금형의 수명에 지대한 영향을 미친다.(중략)

• Journal of the Korean Society for Precision Engineering
• /
• v.23 no.6 s.183
• /
• pp.52-56
• /
• 2006

Punching tools like an electrodes are made by milling or etching or EDM. These methods had time consuming, low efficiency and air pollution. So, we have developed a shearing device which counter punching method for burrless cutting of micro wire. Using the straightened SUS304 wire with $200{\mu}m$ diameter, we confirmed the tendency of the shear plane for punch tools. It was impossible to completely remove the bun in the shearing process. In order to minimize the burr size and fine shear plane, we have accomplished the various experiment conditions such as the U-groove, the effect of the counter punch, shear angle and clearance. The results of the experiments show that indentation, slip plane and bent shape were related to the shear angle and clearance.

• The Journal of Korean Orthopaedic Ultrasound Society
• /
• v.8 no.1
• /
• pp.31-37
• /
• 2015

Lesion of long head of biceps tendon is one of the causes making an anterior shoulder pain. According to the anthropometric study of the bicipital groove the meanings of the width, depth and the medial wall angle were suggested. Confirming the images and location of the long head of biceps tendon itself would be helpful in diagnosis.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2000.11a
• /
• pp.498-501
• /
• 2000

Air dynamic bearings are inherently unstable in dynamic behavior due to the varying angle of a force produced and the nonlinear characteristics of stiffness. In this study, such dynamic behavior is obtained and compared with experimental results. A body axis coordinate system is employed to avoid the change of a moment of inertia. FDM is used to calculate the pressure distribution on the bearing surface and then the force acting on the rotor was calculated by integrating the pressure distribution. By integrating accelerations which are calculated from the equations of motion using the 4th order Runge-Kutta method, the pose of the bearing at each time step is obtained.

• Proceedings of the KSME Conference
• /
• 2001.11b
• /
• pp.741-745
• /
• 2001

The necessity of a Z-shape heat pipe may occur in a special application such as a cooling module for an electronic equipment having a limited accessible space. Either of the two end part works as evaporator or condenser and the length of the middle part is 200mm. The heat pipe was made of 3/8 inch copper tube having 60 spiral groove with screw angle of 10 degrees. Water and acetone were used as working fluids. The fill charge ratio of the working fluid was varied for different values of thermal loads. The thermal resistance was calculated based on the temperature measurements along the heat pipe axis. The maximum thermal loads were 80W for water and 100W for acetone heat pipe. The optimum fill charge ratio was identified through a series of experiments.

• Journal of the Korean Society for Precision Engineering
• /
• v.25 no.3
• /
• pp.50-55
• /
• 2008

In this paper, we propose a new shape compensation scheme to make up for the difference in groove radius between the formed tools and the machined bearing raceways, which inherently takes place during machining the ball bearing raceways by the turning process using conventional formed tools. The associated conventional methods of the formed tool design and its modification such as a simple depth compensation method and a graphical compensation method are introduced and the latter, which has been known to be the better of the two, is experimentally investigated in detail to reveal its drawback. The algorithm is given and it is applied to develop a formed tool design program. The program developed by the presented approach is successfully applied to design the formed turning tool for the bearing raceways.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2006.05a
• /
• pp.165-166
• /
• 2006

Surface pattern of tribological applications is an attractive technology of engineered surface. Therefore, friction reduction is considered to be necessary for improved efficiency of machines. This study investigated the effect of friction property fur angles of micro-scale crosshatch grooved surface pattern on bearing steel flat mated with pin-on-disk. We obtain sample which can be fabricated by photolithography process. We discuss friction property depend on an angle of cross-hatch grooved pattern. We can verify the lubrication mechanism as a Stribeck curve, which has a relationship between the friction coefficient and a dimensionless parameter under the lubrication condition. It was found that the friction coefficient was related to angle of crosshatch on surface, even when surface pattern was the same density.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
• /
• v.13 no.6
• /
• pp.474-481
• /
• 2001

Aluminum/Freon22 grooved hat pipes which have 26 axial grooves in a cross-section were manufactured and tested. The performance test was conducted by varying filling ratio and tilt angle. Operation limit, thermal resistance, overall heat transfer coefficient were investigated. The experimental result was compared with previous study which conducted in the case of a heat pipe with combined wick. The experimental result shows that thermal resistance of this heat pipe is twice smaller than that of the heat pipe with combined wick and operation limit is increased about 75%, comparing with that of heat pipe with combined wick.