• Archives of Pharmacal Research
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• v.28 no.3
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• pp.305-310
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• 2005

It has been suggested that nitric oxide (NO) derived from inducible nitric oxide synthase (iNOS) may act as a mediator of cytokine-induced effects on bone turn-over. NO is also recognized as an important factor in bone remodeling, i.e., participating in osteoblast apoptosis in an arthritic joint. The components of Agastache rugosa are known to have many pharmacological activities. In the present study, we investigated the effects of Agastache rugosa leaf extract (ELAR) on NO production and the iNOS expression in ROS 17/2.8 cells activated by a mixture of inflammatory cytokines including TNF-$alpha$ and IL-1$\beta$. A preincubation with ELAR significantly and concentration-dependently reduced the expression of iNOS protein in ROS 17/2.8 cells activated with the cytokine mixture. Consequently, the NO production was also significantly reduced by ELAR with an IC$_{50}$ of 0.75 mg/mL. The inhibitory mechanism of iNOS induction by ELAR prevented the activation and translocation of NF-$\kappa$B (p65) to the nucleus from the cytosol fraction. Furthermore, ELAR concentration-dependently reduced the cellular toxicity induced by sodium nitroprusside, an NO-donor. These results suggest that ELAR may be beneficial in NO-mediated inflammatory conditions such as osteoporosis.

• Food Science and Preservation
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• v.20 no.3
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• pp.379-385
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• 2013

To establish the optimal manufacturing conditions of soybean koji, soybean Koji prepared with Aspergillus oryzae 6-M-1 and Bacillus subtilis 3-B-1 isolated from traditional Korean meju. During 7 days of making Koji, the amount of amino-type nitrogen was getting more increase. The amount of amino-type nitrogen of Koji prepared with A. oryzae 6-M-1 was 686.16 mg% (w/w), that of Koji with B. subtilis 3-B-1 was 643.46 mg% (w/w) at seventh day of making Koji. The ${\alpha}$-amylase activity of Koji prepared with A. oryzae 6-M-1 was 1472.54 unit/g, that of Koji with B. subtilis 3-B-1 was 791.00 units/g on the seventh day of the making. The acidic protease activity of Koji prepared with A. oryzae 6-M-1 was 309.00 unit/g, that of Koji with B. subtilis 3-B-1 was 135.88 unit/g at 7th day of making. The amount of amino-type nitrogen and enzyme activities of soybean Koji prepared with A. oryzae 6-M-1 and B. subtilis 3-B-1 were produced more than those of wheat flour Koji made in factory. Sensory evaluation on a commercial doenjang and doenjangs prepared with A. oryzae 6-M-1 and B. subtilis 3-B-1 was not significantly different at p<0.05.

• Food Science of Animal Resources
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• v.33 no.2
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• pp.276-280
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• 2013

Obesity, the leading metabolic disease, is a prevalent health problem in industrialized countries and is closely associated with coronary heart disease, hypertension, diabetes, and even cancer. In this study, we investigated the effects of dip-sauce for meat containing Garcinia cambogia extract (GC) on the lipid accumulation and body weight reduction in rats fed high-fat diet for three months. Eighteen Sprague Dawley male rats of five-week-old were randomly assigned to one of three groups; normal chew diet (NCD) group, high-fat diet plus GC-noncontaining dip-sauce (HFD) group, and HFD plus GC-containing dip-sauce (HFD+GC) group. Co-administration of GC-containing dip-sauce (5 g/kg body weight/day) with HFD significantly attenuated cumulative body weight gain, compared with NCD or HFD groups. Both epididymal and perirenal fat pad weights in the HFD plus GC group were significantly lower than those of HFD or NCD groups. Administration of GC-containing dip-sauce also resulted in significant reduction in the serum levels of total cholesterol, total lipid, and triglyceride, compared with NCD or HFD groups. Thus, GC-containing dip-sauce confers beneficial effects to pathological states associated with metabolic disorder via its anti-obesity and lipid lowering properties.

• Journal of Life Science
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• v.24 no.6
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• pp.648-654
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• 2014

Grape pruning stems constitute a scarcely investigated class of byproducts with limited reports on their bioactive polyphenol content and/or industrial applications. Herein we present the outcome of our investigation on grape pruning stems extracts, concerning the assessment of their total polyphenolic content and the detailed evaluation of their antioxidant properties. Results obtained indicate that grape pruning stems are particularly rich in flavonoids and trans-resveratrol. The antioxidant activities was analyzed and expressed as electron donating ability, ABTS cation radical decolorization, hydrogen peroxide scavenging activity and superoxide anion radical scavenging activity, the antioxidant activity of Vitis labrusca L. pruning stems extracted (GPSE) was higher than that of BHA and L-ascrobic acid. The whitening and anti-wrinkle activities display an capability. Results herein grape pruning stems used as a valuable resource for the extraction of resveratrol, which would be added to functional cosmetics and food materials.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2010.05a
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• pp.451-453
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• 2010

The world is rapidly evolving in the future society is based on intelligence. In such circumstances, USN(Ubiquitous Sensor Network) to implement the future ubiquitous(Ubiquitous) society have been highlighted as a key infrastructure. For realization of Ubiquitous computing(Ubiquitous Computing), The data recognized from each sensors must be collected on real-time and transferred to applied service so that they may be used as data for providing service to users. USN sensor data on the use for using a numerous sensor data provision service, service provider can publish its service in standardized registry for users to search and use the service registry. However, in previous studies using Web services standards WS-Eventing, and UDDI(Universal Description, Discovery, and Integration) as USR(USN Service Registry) for USN Application Service is unnecessary or insufficient. In this paper, data from sensors that provide information to service providers register their services and use the information for service users to explore and views on the registry of the system was designed and implemented.

• Korean Journal of Medicinal Crop Science
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• v.18 no.3
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• pp.168-172
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• 2010

This experiment was carried out to investigate the effect of several organic compost on the growth and root yield of Scutellaria baicalensis G. with organic cultivation from 2008 to 2009. Four organic compost were used ; Rice bran compost (RC : 1.1-3.6-1.4), Wheat bran compost (WC: 1.1-3.4-1.4), Hangawi compost (HC : 3.7-4.0-1.0), Cheonnyeonjigi compost (CC : 12.4-3.4-5.4) and Fermented chicken droppings compost (FC : 2.9-6.1-3.2). Organic matter, available phosphate and $K_2O$ of soil increased in all plots with the addition of organic compost, specifically in HC, CC and FC application. Treatment of HC, CC and FC application increased emergence rate and improved the growth characters of shoot, root parts of plants compared to those of RC application. Subterranean part yields by different organic compost was high 149~156 kg per 10a as by growth increment of dried root yield. length of main root and diameter of main root. respectively, 17.4~18.4 cm, 12.65~12.94 mm from HC, CC and FC application. There were significantly positive correlation between the growth characters of shoot, root parts of plants, dry root yield in Scutellaria baicalensis G. grown under organic compost application.

• Journal of Korean Society of Transportation
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• v.27 no.5
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• pp.97-111
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• 2009

Image-based traffic information collection systems have entered widespread adoption and use in many countries since these systems are not only capable of replacing existing loop-based detectors which have limitations in management and administration, but are also capable of providing and managing a wide variety of traffic related information. In addition, these systems are expanding rapidly in terms of purpose and scope of use. Currently, the utilization of image processing technology in the field of traffic accident management is limited to installing surveillance cameras on locations where traffic accidents are expected to occur and digitalizing of recorded data. Accurately recording the sequence of situations around a traffic accident in a signal intersection and then objectively and clearly analyzing how such accident occurred is more urgent and important than anything else in resolving a traffic accident. Therefore, in this research, we intend to present a technology capable of overcoming problems in which advanced existing technologies exhibited limitations in handling real-time due to large data capacity such as object separation of vehicles and tracking, which pose difficulties due to environmental diversities and changes at a signal intersection with complex traffic situations, as pointed out by many past researches while presenting and implementing an active and environmentally adaptive methodology capable of effectively reducing false detection situations which frequently occur even with the Gaussian complex model analytical method which has been considered the best among well-known environmental obstacle reduction methods. To prove that the technology developed by this research has performance advantage over existing automatic traffic accident recording systems, a test was performed by entering image data from an actually operating crossroad online in real-time. The test results were compared with the performance of other existing technologies.

• Journal of the Korean Society for Nondestructive Testing
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• v.22 no.1
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• pp.1-8
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• 2002

The high frequency ultrasonic transducers using polyvinyliden fluoride(PVDF) and polyvinylidene fluoride trifluorethyylene(P(VDF-TrFE)) were developed. The characteristics of fabricated high frequency ultrasonic transducer such as beam diameter, high frequency ultrasonic detection field and amplitude of the first pulse echo signal from the test target in the water were analyzed. The high frequency ultrasonic detection field was affected by the length of coaxial cable between high frequency transducer and ultrasonic pulser/receiver. As the size of the test target increased, the high frequency detection field decreased and the amplitude of a reflection signal increased. The peak amplitude of the first pulse echo signal of P(VDF-TrFE) transducer was higher than that of PVDF transducer. The high frequency ultrasonic detection field of PVDF transducer was wider than that of P(VDF-TrFE) transducer. With C-scan testing, the developed high frequency ultrasonic transducer could detect the 30 to $100{\mu}m$ of hydrogen induced crack of steel specimen by C-scan testing.

• (The)Study of the Eastern Classic
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• no.55
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• pp.35-58
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• 2014

This thesis is about Chungyongkugyongyonui(中庸九經衍義) by HoiJae Lee Eon Jeok (1491~1553). As many know, he was one of the philosophers representing the 16th century who played a great role in making the Zhūzǐ's Neo-Confucianism settle down in Joseon society through the dispute on TaeGeuk (太極) against Cho Han Bo (?~?). He was also the scholar who firmly established the theoretical system of the Idea for Proper Governance (至治主義). The Supplementary Explanation to the Chapters and Phrases of the Great Studies (大學章句補遺) and the Transcript of Nine Annotations on the Middle Way (中庸九經衍義) were written to argue his thoughts of the Idea for Proper Governance shown in the Great Studies (大學) and the Middle Way (中庸). He said that the Great Studies was more specific in the clauses for the justice of training oneself while the Middle Way more detail in the clauses for the justice of governor. That is, he thought that those books were in the relation of the in-and-outside, so that he argued that kings should take both justices of such for governance. Especially the Transcript of Nine Annotations on the Middle Way was written by following the way of the Annotation Transcript of the Great Studies (大學衍義) by Jin Deok Su (眞德秀), a scholar of Song Dynasty and the Supplementary Explanation to the Annotation Transcript of the Great Studies (大學衍義補) in order to make the King MyeongJong of that period realize the Proper Governance of the Two Great Emperors and Three Great Kings of Ancient China, which greatly influenced the Ten Figures of the Studies for the Great Man (聖學十圖) by ToiGye Lee Hwang and the Abstract of the Studies for the Great Man (聖學輯要) by YulGok Lee Yi.

• Journal of Aerospace System Engineering
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• v.16 no.3
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• pp.105-114
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• 2022

The purpose of this study was to present a conceptual design of the 6U micro-satellite system for optical image of 3 m GSD. An optical camera system with a payload of 3 m GSD image was designed and optimized. The optical system has a diameter of Ø78 mm, length 250 mm, and 1400 mm focal length. The requirement and constraints were configured for the 6U micro-satellite bus system with the payload. Satisfying the requirement and constraints, the subsystems of the 6U bus were designed such as attitude and orbit control, propulsion, command and data handling, electrical power, communication, structures and mechanisms, and thermal control subsystem. The mass budget, power budget, and communication link budget were also confirmed for the 6U micro-satellite comprising the optical payload and the subsystems of bus. To take optical images, a mission operation concept is proposed for the 6U micro-satellite in a low-Earth orbit. A constellation comprising many 6U micro-satellites studied in this paper, can provide with various data for reconnaissance and disaster tracking.