• 제목/요약/키워드: Genetic Operation

검색결과 390건 처리시간 0.026초

국내.외 조류인플루엔자(HPAI) 발생현황과 대응방안 (The outbreaks and counterplan of highly pathogenic avian influenza in Korea and overseas)

  • 장형관
    • 한국환경농학회:학술대회논문집
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    • 한국환경농학회 2009년도 정기총회 및 국제심포지엄
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    • pp.220-227
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    • 2009
  • For last about 10 years, the Republic of Korea experienced 3 times of outbreaks of highly pathogenic avian influenza (HPAI) from 10 December 2003 to 30 April 2004 (a total number of 19 outbreaks), 22 November 2006 to 6 March 2007 (a total number of 7 outbreaks), and 1 April 2008 to 12 May 2008 (a total number of 33 outbreaks). Among the totally 59 outbreaks, the infected premises included 35 chicken farms, 17 duck farms, 1 quail farm, and 6 farms rearing mixed species. Control measures were applied according to the HPAI standard operation procedure including depopulation of all infected and suspected flocks, movement restrictions, and disinfection of the infected farms within a 500-meter radius. Including movement restrictions, stringent control measures were additionally applied to two designated zones: the protection zone was an area within a 3-kilometer radius of the outbreak farm, and the surveillance zone was an area between a 3- to 10-kilometer radius of the outbreak farm. Farms with dangerous contacts and/or all of poultry within the protection zone was subjected to preemptive culling. Epidemiological investigations were also carried out including trace-back and trace-forward investigations to identify possible sources of spread and dangerous contact farms. Investigation teams conducted on-site examination of farm premises and facilities, interview with farm owner and staff, and review of records. Genetic and pathogenic characteristics of the virus isolates, and the results of the various surveillance activities were also analyzed. HPAI surveillance conducted in Korea includes passive surveillance of investigating notified cases, and active surveillance of testing high risk groups and areas. HPAI is a notifiable disease in Korea and all suspect cases must be reported to the veterinary authorities. Cases reported for other poultry diseases that require differential diagnosis are also tested for HPAI. Active surveillance includes annual testing of breeder duck farms, broiler duck farms and wild bird surveillance, which is concentrated during the autumn and winter. Surveillance activities conducted prior to the outbreaks have shown no evidence of HPAI infection in Korea.

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감응식 신호운영을 위한 최대녹색시간의 설계 (Design of Maximum Green Time Parameters for Traffic Actuated Operation)

  • KIM, Jin Tae
    • 대한교통학회지
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    • 제20권4호
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    • pp.123-134
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    • 2002
  • 감응식 신호운영변수 설계에 관한 연구는 정주기식 신호운영변수 설계의 그것보다 그 수준이 현저히 미비하며 이는 감응식 신호운영 특성을 반영한 평가방법의 부재로 감응식 운영변수의 평가가 불가능하였기 때문이다. 본 논문은 최근에 소개된 평균 감응현시 녹색시간 추정 수리모형을 이용하여 Highway Capacity Manual (HCM) 지체도를 최소화하는 최대녹색시간의 설계방안을 제시한다. - '최소녹색시간'과 '단위연장시간'은 보행자 횡단시간 및 차량 차두시간 등 지역별 운전자/보행자의 특성과 관련이 있어 일반적인 최적화 설계 수리모형의 적용에 무리가 있어 제외한다. 제안된 설계방안은 감응식 운영논리를 토대로 감응현시 군의 평균녹색시간과 평균주기를 산정하며, HCM 지체도를 평가하고, 가능한 대안 중 지체를 최소화하는 최대녹색시간 운영변수 군을 '혼혈 유전자 알고리즘'으로 도출한다. 현장실험을 통해 도출이 불가능한 실제 최적치를 Corridor Simulation(CORSIM)모형을 이용하여 추정하였고 이를 제안된 설계방안으로 도출된 최대녹색시간 운영변수' 값들과 비교하였다. 비교결과 교차로 v/c 비율이 1.0 보다 낮을 시는 제안된 방법을 통해 설계된 최대녹색시간 운영변수 군이 최소 CORSIM 지체도를 산출하는 최대녹색시간 운영변수 군과 동일한 것으로, v/c비율이 1.0보다 높을 시는 다른 것으로 결과되었다. v/c비율이 1.0 보다 높은 경우는 정주기식 교차로 운영에 효율적이라 감응식 운영의 필요를 벗어나므로 제안된 최대녹색시간 설계방안은 감응식 신호운영 필요범위 내에서 효율적이다. 기존의 최대녹색시간 설계는 정수기식 최적녹색시간을 기준으로 최대녹색시간을 추정하며, 그러한 과정을 돕기 위하여 추정범위(설계자가 범위 내에서 임의로 선택함)를 제시하는 것이 기존의 연구임을 비교하면 본 연구에서 제안하고 있는 설계방법의 의미가 크다.

크리깅 메타모델에 기반한 다목적최적설계 전략과 액셜 피스톤 펌프 설계에의 응용 (Multiobjective optimization strategy based on kriging metamodel and its application to design of axial piston pumps)

  • 정종현;백석흠;서용권
    • Journal of Advanced Marine Engineering and Technology
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    • 제37권8호
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    • pp.893-904
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    • 2013
  • NSGA-II와 함께 크리깅 메타모델기반 다목적최적설계 전략을 3차원 CFD 시뮬레이션을 통해 액셜 피스톤 펌프의 밸브 플레이트 형상을 최적화하는데 적용하였다. 펌프의 압력 변동을 저감하고 수력 효율을 최대화하기 위한 최적설계 과정은 두 단계, 즉 (1) 밸브 플레이트 상의 6개 형상 설계 변수를 선정하고 각 설계변수의 변화에 따른 CFD 해석을 수행하며, (2) CFD 데이터를 이용한 NSGA-II에 기반한 다목적최적설계 접근방식으로 최소 맥동 압력과 펌프 효율 설계에 대해 파레토 프론트를 평가하는 것으로 구성된다. 이들 결과로부터 최소 맥동 압력을 가지며 액셜 피스톤 펌프의 목표 효율에 도달하는 최적 절충해를 선택할 수 있었다.

전력 시스템의 동요 억제를 위한 TCSC용 안정화 장치 설계 (A Design of Power System Stabilization of TCSC System for Power system Oscillation Damping)

  • 정형환;허동렬;왕용필;박희철;이동철
    • 조명전기설비학회논문지
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    • 제16권2호
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    • pp.104-112
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    • 2002
  • 본 논문에서는 FACTS 기기의 일종인 전력조류 극대화 및 제어 기능과 함께 외란에 의한 과도시의 전력계통 안정화 기능을 수행할 수 있는 TCSC용 전력시스템 안정화 장치 설계에 대하여 연구하였다. TCSC용 전력시스템 안정화 장치 설계시 파라미터 선정은 복잡한 수식이 필요 없고 계산시간을 감소시키며 적은 반복횟수로도 최적해를 찾을 수 있는 자연 생태계의 진화를 모의한 유전 알고리즘을 이용하였다. 전력 시스템의 저주파 진동에 강인성을 갖는 TCSC는 TCR(Thyristor Controlled Reactor)과 커패시터의 병렬구조에 의해 용량성과 유도성에 걸친 범위가지 연속적으로 제어할 수 있는 구조로 이루어져 있다. 이러한 제안된 방법의 강인성을 검증하기 위해 여러 가지 운전조건에 대해 전력계통 안정도 및 고유치를 해석하여 기존의 안정화 장치를 적용한 경우와 비교함 으로써 유용성을 입증하였다.

Fundamental framework toward optimal design of product platform for industrial three-axis linear-type robots

  • Sawai, Kana;Nomaguchi, Yutaka;Fujita, Kikuo
    • Journal of Computational Design and Engineering
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    • 제2권3호
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    • pp.157-164
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    • 2015
  • This paper discusses an optimization-based approach for the design of a product platform for industrial three-axis linear-type robots, which are widely used for handling objects in manufacturing lines. Since the operational specifications of these robots, such as operation speed, working distance and orientation, weight and shape of loads, etc., will vary for different applications, robotic system vendors must provide various types of robots efficiently and effectively to meet a range of market needs. A promising step toward this goal is the concept of a product platform, in which several key elements are commonly used across a series of products, which can then be customized for individual requirements. However the design of a product platform is more complicated than that of each product, due to the need to optimize the design across many products. This paper proposes an optimization-based fundamental framework toward the design of a product platform for industrial three-axis linear-type robots; this framework allows the solution of a complicated design problem and builds an optimal design method of fundamental features of robot frames that are commonly used for a wide range of robots. In this formulation, some key performance metrics of the robot are estimated by a reducedorder model which is configured with beam theory. A multi-objective optimization problem is formulated to represent the trade-offs among key design parameters using a weighted-sum form for a single product. This formulation is integrated into a mini-max type optimization problem across a series of robots as an optimal design formulation for the product platform. Some case studies of optimal platform design for industrial three-axis linear-type robots are presented to demonstrate the applications of a genetic algorithm to such mathematical models.

痔瘡과 痔瘻에 對한 文獻的 考察 (A Literatural study on the hemorrhoids and hemorrhoids complicated by anal fistula)

  • 노현찬;노석선
    • 한방안이비인후피부과학회지
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    • 제10권1호
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    • pp.284-305
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    • 1997
  • A Literatural study on the etiological factors, classification, prescription of hemorrhoids and hemorrhoids complicated by anal fistula following results were obtained. 1. The cause of hemorrhoids are long time sit, long time gate, overfatigue, overeating, imbalance of stool( constipation or diarrhea), pregnant fertility(overfatigue after childbirth, insufficiency of middle warmer energy), uncontrol sexual excess, pathgenic factors of wetness, heat, wind, dry, genetic cause, excess of anxiety, pile up of heat poison, weakness of entrails and viscera. The cause of hemorrhoid complicated by anal fistula are attack of external wind, heatness, dry, fire, wetness(pathgenic factors), inapporiate treatment and chronic disease, greasy diet, excess of anxiety, constipation, uncontrol sexual excess, obstacle of circulation of vital energy and blood on anal site. 2. Classification of hemorrhoids are female hemorrhoids, male hemorrhoids, pulse hemorrhoids, intestines hemorrhoids, vital energy hemorrhoids, wine hemorrhoids, blood hemonhoids, flowing hemorrhoids. Classification with other method are external hemorrhoids, internal hemorrhoids, mixed hemorrhoids, excrescence hemorrhoids, nipple homorrhoids. External hemorrhoids is classified of varicosis of hemorrhoidal vein, connective tissue form, thrombus form. Classification of hemorrhoid complicated by anal fistula are simple lower hemorrhoid, lower mixed hemorrhoid, deep hemorrhoid, outer of one hole hemorrhoid, a horseshoe hemorrhoids. Once more classificated of four are space of sphincter muscle form, penetration sphincter muscle form, upper of sphincter muscle form, outer of sphincter muscle form. 3. Therapy method of hermorrhoid and hemorrhoid complicated by anal fistula are internal method, fumigation method method, ointment, method of close with medicine, necrotizing method, hot medicated compress( gxternal method), injection, insertion, bind, (operation) and acupuncture therapy (the others method) 4. Herb medicine for many used of internal method are Scutellaria baikalensis George(黃芩), Coptis japonia Makino(黃連), Rehmania giutinosa Liboschitz ex Fischer & Meyer(生地黃), Poncirus trifoliata Refinesque(枳殼), Sanguisorba officinalis Linne(地楡), Sophora japonica L.(槐花), Cnidium officinale Makino (川芎), Astragalus membranaceus Bunge(황기), Angelica gigas Nakai (當歸). 5. Herb medicine for many used of fumigation are Schlechtendalia Chinesis J. Bell (五倍子), Artemisia Vulgaris L. var indica Maxim(艾葉), Poncirus trifoliata Refinesque (枳殼), Nepeta japonica Maximowicy(荊芥), And herb medicine for many used of ointment are Calomelas(輕粉), Alum(白礬), Boswellia carterii Birdwood(乳香), Os Draconis Fossilia Ossis Mastodi(龍骨).

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주문생산을 위한 APS 와 효율적 구매의 통합모델 (Integrated Supply Chain Model of Advanced Planning and Scheduling (APS) and Efficient Purchasing for Make-To-Order Production)

  • 정찬석;이영해
    • 한국경영과학회:학술대회논문집
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    • 대한산업공학회/한국경영과학회 2002년도 춘계공동학술대회
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    • pp.449-455
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    • 2002
  • This paper considers that advanced planning and scheduling (APS) in manufacturing and the efficient purchasing where each customer order has its due date and multi-suppliers exit We present a Make-To­Order Supply Chan (MTOSC) model of efficient purchasing process from multi-suppliers and APS with outsourcing in a supply chain, which requires the absolute due date and minimized total cost. Our research has included two states. One is for efficient purchasing from suppliers: (a) selection of suppliers for required parts; (b) optimum part lead­time of selected suppliers. Supplier selection process has received considerable attention in the business­management literature. Determining suitable suppliers in the supply chain has become a key strategic consideration. However, the nature of these decisions usually is complex and unstructured. These influence factors can be divided into quantitative and qualitative factors. In the first level, linguistic values are used to assess the ratings for the qualitative factors such as profitability, relationship closeness and quality. In the second level a MTOSC model determines the solutions (supplier selection and order quantity) by considering quantitative factors such as part unit price, supplier's lead-time, and storage cost, etc. The other is for APS: (a) selection of the best machine for each operation; (b) deciding sequence of operations; (c) picking out the operations to be outsourcing; and (d) minimizing makespan under the due date of each customer's order. To solve the model, a genetic algorithm (GA)-based heuristic approach is developed. From the numerical experiments, GA­based approach could efficiently solve the proposed model, and show the best process plan and schedule for all customers' orders.

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Design of Quorum Quenching Microbial Vessel to Enhance Cell Viability for Biofouling Control in Membrane Bioreactor

  • Cheong, Won-Suk;Kim, Sang-Ryoung;Oh, Hyun-Suk;Lee, Sang H.;Yeon, Kyung-Min;Lee, Chung-Hak;Lee, Jung-Kee
    • Journal of Microbiology and Biotechnology
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    • 제24권1호
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    • pp.97-105
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    • 2014
  • Quorum quenching (QQ) with a microbial vessel has recently been reported as an economically feasible biofouling control platform in a membrane bioreactor (MBR) for wastewater treatment. In this study, a quorum quenching MBR with a ceramic microbial vessel (CMV) was designed to overcome the extremely low F/M ratio inside a microbial vessel. The CMV was prepared with a monolithic ceramic microporous membrane and AHL-degrading QQ bacteria, Pseudomonas sp. 1A1. The "inner flow feeding mode" was introduced, under which fresh feed was supplied to the MBR only through the center lumen in the CMV. The inner flow feeding mode facilitated nutrient transport to QQ bacteria in the CMV and thus enabled relatively long-term maintenance of cell viability. The quorum quenching effect of the CMV on controlling membrane biofouling in the MBR was more pronounced with the inner flow feeding mode, which was identified by the slower increase in the transmembrane pressure as well as by the visual observation of a biocake that formed on the used membrane surface. In the QQ MBR with the CMV, the concentrations of extracellular polymeric substances were substantially decreased in the biocake on the membrane surface compared with those in the conventional MBR. The CMV also showed its potential with effective biofouling control over long-term operation of the QQ MBR.

혼승 및 시간대별 학생들의 동적유입을 고려한 스쿨버스 경로 문제 (School Bus Routing Problem with Mixed-Load and Dynamic Arrivals)

  • 이영기;정석재;윤호영;김경섭
    • 한국시뮬레이션학회논문지
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    • 제22권1호
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    • pp.63-75
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    • 2013
  • 스쿨버스 경로문제는 학생들을 다수의 승차지점으로부터 학생들의 해당 학교까지 안전하고 효율적으로 수송할 수 있는 방법을 찾는 문제이다. 일반적인 스쿨버스 경로문제의 제약 조건으로는 차량의 용량, 학생의 최대 수송 시간, 학교의 도착 시간 제약 등이 있다. 본 연구에서는 기존의 혼승을 허용한 스쿨버스 경로 문제를 확장한 모델을 구축하고, 국내의 대학교 스쿨버스 운영 형태를 고려하여 학생들이 승차지점에 유동적으로 유입이 되는 상황을 고려한다. 본 연구에서 제시하는 모델에 대한 실험을 하기 위하여, 첫 단계로 Sweep Algorithm을 이용하여 초기 경로를 구성한다. 두 번째 단계에서는 전역탐색 능력이 있는 메타 휴리스틱 방법인 Genetic Algorithm을 이용하여 최선해을 도출 한다. 또한, 기존의 스쿨버스 경로문제에 적용되었던 현실 가능성 있는 제약들을 완화하여 다양한 시나리오를 구성하고 시나리오별 비교우위 평가를 한다.

비만의 원인과 치료에 대한 동서의학적 고찰 (Oriental and Western Medical Study on the cause and treatment of Obesity)

  • 이상봉;금동호;이명종
    • 동국한의학연구소논문집
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    • 제5권
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    • pp.33-52
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    • 1996
  • The purpose of this study was to investigate efficient treatment in obesity. In order to help clinical application in obesity treatment, this study was performed to investigate the cause and treatment in obesity. The main finding of this study were as follows. 1. In the cause of oriental medicine in obesity, that were moisture(濕), phlegm(痰), gore(瘀), the productive heat(積熱), overeating, supemutrition, underaction, heredity and habitude, psychologic factor(stress) etc. 2. In the western medicine, the cause of obesity were genetic cause, endocrine disorder, hypothalamic extraodinary and secondary effect of drug. But simple obesity is the greater part. Also there were psychologicai and environmental causes. 3. Ear acupuncture of wide application were Naebunbi, Sinmun, Taejang, $ij{\check{o}}m$, $Pyej{\check{o}}m$, $Bij{\check{o}}m$ etc. 4. Body acupuncture of application were $Naej{\check{o}}ng$, $Sangg{\check{o}}h{\check{o}}$, Pungnyung, Kokchi, $Sam{\check{o}}mgyo$, $Umn{\check{o}}ngch{\check{o}}n$ etc. 5. In oriental medical treatment of obesity, Bangpungtongs ngsan(防風通聖散), Daesihotang(大柴胡湯), Seungkitang(承氣湯), Bangkihwangkitang(防己黃?湯), Richulsaryeungtang(二朮四笭湯), Taeksatang(澤瀉湯), Opieum(五皮飮), Gongyundan(控涎丹) etc were wide applicated. 6. The western medical treatment in obesity encourage the dietary cure, exercise cure and behavior adjustment than medical therapy or operation. In treatment of obesity, the dietary cure and herb-drug therapy, ear acupuncture and body acupuncture are effective. But weight maintenance after treating is more important. After all the continuous dietary cure, behavior adjusting cure and exercise cure are necessary.

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