• 약학회지
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• 제55권3호
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• pp.195-202
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• 2011

Generic medication market has been increased for economic reasons in Korea. Health authorities worldwide recommend the use of generic medications nowadays. However, patients in Korea are not familiar with the generic medications and considerable percent of those do not know the definition of the generic medications. The purpose of this study was to evaluate adults' knowledge and perception on the generic medications at community pharmacies in Korea. This study was a 11-questionnaire survey conducted from August 9, 2010 to August 27, 2010. Of the 204 respondents, 63 (30.9%) responded that they knew what a generic medication was, but only 16 (25.4%) of those answered that generic medications had the same efficacy as brand medications. When pharmacists were the source of generic medication information, more patients reported having knowledge about the definition of generic medications correctly compared with other sources. Patients with negative experience with generic medications within 6 months were more reluctant to generic substitution suggested by a pharmacist than those with positive experience. Based on the results of this study, further studies should be conducted to establish the best way to provide generic medication information for patients.

• 약학회지
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• 제58권2호
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• pp.99-106
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• 2014

This study explores the prescribing pattern of generic drugs and the relationship between socio-demographic factors and the use of generics in South Korea. The analysis was based on claims data of 2011 from Korean National Health Insurance. We examined utilization, costs, and market share of oral preparations by original and generic product. Multiple logistic regression was performed to evaluate the predictive factors of generic use among multi-source medications. Generics accounted for 37~41% of utilization and 34~41% of costs in the insured market of oral preparations. In the generic market, costly generics made up about 58~61%, 56~66% of volume and value, respectively. Other things being equal, institutional factors affected generic use to the largest degree. The odds of having generics were 6 times higher in clinics, 4 times higher in hospitals, and 1.7 times higher in general hospitals than in teaching hospitals. Those in metropolitan or rural area were more likely to prescribe generics than those in the capital area. While generics were frequently prescribed for off-site pharmacy (OR=1.173), the odds of having generics was 0.88 after weighting the data by units prescribed. This study empirically presented the pattern of generic prescribing, confirming the widely accepted view that costly generics were more likely to be utilized in the Korean market. Up to two thirds of the generic market consisted of costly products. The strongest factors affecting generic use were institutional variables.

• 보건행정학회지
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• 제23권3호
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• pp.210-223
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• 2013

Backgrounds: Escalating pharmaceutical expenditure has threatened the sustainability of National Health Insurance system in Korea. Generic medicines allow patients to access safe, effective, high-quality medicines at low cost, thus insurers could achieve significant financial savings by promotion of generics, if they are priced much lower than the originator. The purpose of this study was to review generic pricing as well as promotion policies in other countries and assess the implication of those policies. Methods: We reviewed the main measures adopted by the developed countries such as Austria, Belgium, Denmark, Finland, France, Germany, Italy, Japan, Netherlands, Norway, Sweden, United Kingdom, especially in countries where governments are the largest third-party payers or insurance finance resource is the national health insurance. Results: The foreign countries's experience with generic medicine policy shows that demand-side policies such as physician budgets, international nonproprietary name prescribing, generics substitution, patients co-payment as well as supply-side policies relating to pricing and reimbursement seems to play a critical role in developing the generic medicines market. Conclusion: Various strategy should be implemented to promote generic drug use.

• Communications for Statistical Applications and Methods
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• 제13권2호
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• pp.285-295
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• 2006

As more generic drugs become available, the quality, safety, and efficacy of generic drugs have become a public concern. Specifically, drug interchangeability among generic copies of the same brand-name drug is a safety concern. This research proposes a Bayesian method for assessing bioequivalence between two generic copies of the same brand-name drug from two independent $2{\times}2$ crossover design experiments. Uninformative priors are considered for general use and the posterior distribution of the difference of two generic drug effects is derived from which the highest probability density interval can be evaluated. Examples are presented for illustration.

• 한국항행학회논문지
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• 제12권5호
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• pp.502-508
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• 2008

인터넷의 급속한 확산과 대량 정보의 이동은 문서요약을 더욱 필요 하고 있다. 본 논문은 비음수 행렬 인수분해로 얻어진 비음수 의미 가변 행렬과 의미특징의 포괄적 중요도를 이용하여 문장을 추출하여서 포괄적 문서요약을 하는 새로운 방법을 제안하였다. 제안된 방법은 인간의 인식 과정과 유사한 비음수 제약을 사용한다. 이 결과 주제의 군집방법이나 잠재의미분석을 사용한 비지도 학습방법에 비해 더욱 의미 있는 문장을 선택하여 문서를 요약할 수 있다. 실험결과 제안방법이 다른 방법들에 비하여 좋은 성능을 보인다.

• 한국전자거래학회지
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• 제8권1호
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• pp.103-111
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• 2003

Nowadays XML is used for exchanging information in e-Commerce, especially B2B. Necessity of XML DBMS has being increased to efficiently process XML data. So a lots of database products for supporting XML are rapidly appeared in the market. In this paper, we made an XML DBMS system based on Generic Data Model. First we developed XML Adaptor based on Generic Data Model and added it on relational DBMS for developing XML DBMS. XML Adaptor is composed of Query Convertor and XML Repository System. The Query Convertor parse commands that are for XML data manipulation and then call the relevant component of XML Repository System for relational database operation. The XML Repository System handles relational database operations such as create, delete, store, and etc. In this way we can use a relational DBMS for manipulation XML data. Therefor we can build more economically XML DBMS.

• 한국전자통신학회논문지
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• 제8권8호
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• pp.1187-1193
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• 2013

본 논문은 사실적인 3D 얼굴 모델링과 얼굴 표정 생성 시스템을 제안한다. 사실적인 3D 얼굴 모델링 기법에서 개별적인 3D 얼굴 모양과 텍스쳐 맵을 만들기 위해 Generic Model Fitting 기법을 적용하였다. Generic Model Fitting에서 Deformation Function을 계산하기 위해 개별적인 얼굴과 Generic Model 사이의 대응점을 결정하였다. 그 후, Calibrated Stereo Camera로부터 캡쳐 된 영상들로부터 특징점을 3D로 복원하였다. 텍스쳐 매핑을 위해 Fitted된 Generic Model을 영상으로 Projection하였고 사전에 정의된 Triangle Mesh에서 텍스쳐를 Generic Model에 매핑 하였다. 잘못된 텍스쳐 매핑을 방지하기 위해, Modified Interpolation Function을 사용한 간단한 방법을 제안하였다. 3D 얼굴 표정을 생성하기 위해 Vector Muscle기반 알고리즘을 사용하고, 보다 사실적인 표정 생성을 위해 Deformation 과 vector muscle 기반의 턱 rotation을 적용하였다.

• 한국경영과학회지
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• 제37권4호
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• pp.139-151
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• 2012

This paper introduces an Internet-based generic simulator for outpatient clinics, named PIOS (Postech Internet-based Outpatient Simulator). Unlike other simulation tools, PIOS is operated on the Internet, is straightforward to use for outpatient process analysis, and is open to public via http://logistics.postech.ac.kr/pios with free of charge. Therefore, non-simulation expert users such as hospital administrators and managers can easily access to PIOS and conduct simulation study by themselves. In this paper, we describe the main components and programming logic of PIOS, and demonstrate its validity by comparing the output results of PIOS and a commercial software package.

• 한국철도학회논문집
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• 제8권6호
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• pp.539-543
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• 2005

This paper proposed the EGBOM, Extended Generic BOM, which is more flexible BOM system than GBOM. The GBOM system has the limitation to construct Result BOM and to select options by choosing only one Variant under given Cluster. In order to overcome this limitation, we propose the EGBOM which can make more various Result EGBOM, which can use to rolling stock through constructing urban transit BOM using the proposed EGBOM. The last, this paper describes the various Result BOM examples constructed from Source BOM of UT_EGBOM, such as rolling-stock maintenance BOM, individual car BOM, etc.

• Journal of Pharmaceutical Investigation
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• 제34권4호
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• pp.333-340
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• 2004

A new medical system of separation of dispensary from medical practice was started in 2000 in Korea. To expand bioequivalence-proven drug products and to ensure the credibility of the therapeutic equivalence of generic drug are hot issues in Korea. The KFDA also has a plan to revise the pharmaceutical affairs law that bioequivalence reports of all the generic prescription drugs should be submitted to the KFDA in the application for drug approval. Therefore, it becomes more necessary to develop bioequivalence-demonstrating methods for specific preparations such as topical drug products. There are some differences between US and Japanese guidances of bioequivalence studies of generic drug products for topical use. In this paper, we examined the recently published Japanese guideline, Guideline for Bioequivalence Studies of Generic Products For Topical Uses, and Q&A of the guideline, which will be references to make a guidance on bioequivalence studies of topical drug products in Korea.