• 제목/요약/키워드: Generic

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지역약국 방문 성인의 제네릭 의약품 인식도 평가 (Evaluation of Adults' Knowledge on Generic Medications in Korea)

  • 이유정
    • 약학회지
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    • 제55권3호
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    • pp.195-202
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    • 2011
  • Generic medication market has been increased for economic reasons in Korea. Health authorities worldwide recommend the use of generic medications nowadays. However, patients in Korea are not familiar with the generic medications and considerable percent of those do not know the definition of the generic medications. The purpose of this study was to evaluate adults' knowledge and perception on the generic medications at community pharmacies in Korea. This study was a 11-questionnaire survey conducted from August 9, 2010 to August 27, 2010. Of the 204 respondents, 63 (30.9%) responded that they knew what a generic medication was, but only 16 (25.4%) of those answered that generic medications had the same efficacy as brand medications. When pharmacists were the source of generic medication information, more patients reported having knowledge about the definition of generic medications correctly compared with other sources. Patients with negative experience with generic medications within 6 months were more reluctant to generic substitution suggested by a pharmacist than those with positive experience. Based on the results of this study, further studies should be conducted to establish the best way to provide generic medication information for patients.

총칭문과 복수성 (Plurality in Generic Sentences)

  • 조영순
    • 한국언어정보학회지:언어와정보
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    • 제5권2호
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    • pp.75-86
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    • 2001
  • Generic sentences assert generic properties of single individuals or those of plural individuals. It means the generic quantifier Gen can quantify over single and plural entities. Among the generic meaning information represented in terms of the tripartite structure, the information not in the nuclear scope part, but rather in the restrictor part is related to which individuals generic sentences assert of. The plurality in the nuclear scope part cannot be described by making the generic operator Gen quantify over plural entities: Generic sentences with collective predicates like gather, and those with dependent plurals predicate of generic properties of single individuals. On the contrary, the plural information in restrictor part leads Gen to quantify eve. plural entities.

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G.718 초광대역 코덱의 음질 향상을 위한 개선된 Generic Mode Coding 방법 (Modified Generic Mode Coding Scheme for Enhanced Sound Quality of G.718 SWB)

  • 조근석;정상배
    • 말소리와 음성과학
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    • 제4권3호
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    • pp.119-125
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    • 2012
  • This paper describes a new algorithm for encoding spectral shape and envelope in the generic mode of G.718 super-wide band (SWB). In the G.718 SWB coder, generic mode coding and sinusoidal enhancement are used for the quantization of modified discrete cosine transform (MDCT)-based parameters in the high frequency band. In the generic mode, the high frequency band is divided into sub-bands and for every sub-band the most similar match with the selected similarity criteria is searched from the coded and envelope normalized wideband content. In order to improve the quantization scheme in high frequency region of speech/audio signals, the modified generic mode by the improvement of the generic mode in G.718 SWB is proposed. In the proposed generic mode, perceptual vector quantization of spectral envelopes and the resolution increase for spectral copy are used. The performance of the proposed algorithm is evaluated in terms of objective quality. Experimental results show that the proposed algorithm increases the quality of sounds significantly.

3단계 베이지안 처리절차 및 신뢰도 자료 처리 코드 개발 (Development of the 'Three-stage' Bayesian procedure and a reliability data processing code)

  • 임태진
    • 경영과학
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    • 제11권2호
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    • pp.1-27
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    • 1994
  • A reliability data processing MPRDP (Multi-Purpose Reliability Data Processor) has been developed in FORTRAN language since Jan. 1992 at KAERI (Korean Atomic Energy Research Institute). The purpose of the research is to construct a reliability database(plant-specific as well as generic) by processing various kinds of reliability data in most objective and systematic fashion. To account for generic estimates in various compendia as well as generic plants' operating experience, we developed a 'three-stage' Bayesian procedure[1] by logically combining the 'two-stage' procedure[2] and the idea for processing generic estimates[3]. The first stage manipulates generic plant data to determine a set of estimates for generic parameters,e.g. the mean and the error factor, which accordingly defines a generic failure rate distribution. Then the second stage combines these estimates with the other ones proposed by various generic compendia (we call these generic book type data). This stage adopts another Bayesian procedure to determine the final generic failure rate distribution which is to be used as a priori distribution in the third stage. Then the third stage updates the generic distribution by plant-specific data resulting in a posterior failure rate distribution. Both running failure and demand failure data can be handled in this code. In accordance with the growing needs for a consistent and well-structured reliability database, we constructed a generic reliability database by the MPRDP code[4]. About 30 generic data sources were reviewed and available data were collected and screened from them. We processed reliability data for about 100 safety related components frequently modeled in PSA. The underlying distribution for the failure rate was assumed to be lognormal or gamma, according to the PSA convention. The dependencies among the generic sources were not considered at this time. This problem will be approached in further study.

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Statin 계열 약물의 제네릭 및 브랜드 제품 간 임상 치료결과 비교를 위한 체계적 문헌 고찰 (Systematic Review on Clinical Equivalence of Generic and Brand-name Drugs in Statin Therapy)

  • 심해리;이인향
    • 한국임상약학회지
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    • 제27권2호
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    • pp.105-112
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    • 2017
  • Background: Generic medications are approved on the basis of bioequivalence with brand medications in healthy volunteers rather than the target population, there remains a substantial uncertainty regarding their clinical effectiveness and safety. The object of this paper is to compare the clinical equivalence of generic statin drugs in patients. Methods: Literature published before September 2016, which is indexed in PubMed, EMBASE, RISS, comparing generic to brand products in statins. Outcomes included blood lipid level, proportion of days covered (adherence), hospitalization and mortality. Results: 511 citations were screened, of which 11 studies met eligibility criteria (6 randomized clinical trials, 5 observational studies). Generic atorvastatin was clinical equivalent with brand drugs in blood lipid level (3 RCTs) and generic simvastatin was also clinical equivalent with brand drugs (2 RCTs). 2 of 3 studies reported no significant difference in proportion of days covered except 1 study which reported generic statin significantly enhance proportion of days covered (p<0.001). Hospitalization was no significant difference in all studies (p>0.05). 1 study reported that all cause of mortality was significantly low in generic drugs (p<0.0001). Conclusion: Published data on comparing clinical efficacy of generic and brand statins were insufficient in both quantity and quality. This systematic review suggests that additional studies on clinical equivalence and safety of generic medications in patients would be needed.

Generic Modeling System 개발 및 응용사례 (Generic Modeling System)

  • 조유정;임기수;나재일;이장열
    • 한국CDE학회지
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    • 제3권3호
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    • pp.36-45
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    • 1997
  • This paper presents the research on the development of Generic modeling system as a 3D CAD customizing system for the elevator design. This system enables to create a generic model which gives birth to many models. The generic model is expressed as a non-scale model or a standard model in this paper. Using the parametric design techniques, all their relationships are explicitly represented in the tables, not represented in implicit embedded coding. Owing to this method, designers can easily extend the generic model to contain more model families. All parametric relations are stored in relational database. A designer can retrieve various models from a generic model automatically, by using some key input values.

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Hybridized Decision Tree methods for Detecting Generic Attack on Ciphertext

  • Alsariera, Yazan Ahmad
    • International Journal of Computer Science & Network Security
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    • 제21권7호
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    • pp.56-62
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    • 2021
  • The surge in generic attacks execution against cipher text on the computer network has led to the continuous advancement of the mechanisms to protect information integrity and confidentiality. The implementation of explicit decision tree machine learning algorithm is reported to accurately classifier generic attacks better than some multi-classification algorithms as the multi-classification method suffers from detection oversight. However, there is a need to improve the accuracy and reduce the false alarm rate. Therefore, this study aims to improve generic attack classification by implementing two hybridized decision tree algorithms namely Naïve Bayes Decision tree (NBTree) and Logistic Model tree (LMT). The proposed hybridized methods were developed using the 10-fold cross-validation technique to avoid overfitting. The generic attack detector produced a 99.8% accuracy, an FPR score of 0.002 and an MCC score of 0.995. The performances of the proposed methods were better than the existing decision tree method. Similarly, the proposed method outperformed multi-classification methods for detecting generic attacks. Hence, it is recommended to implement hybridized decision tree method for detecting generic attacks on a computer network.

GEOMETRIC CHARACTERISTICS OF GENERIC LIGHTLIKE SUBMANIFOLDS

  • Jha, Nand Kishor;Pruthi, Megha;Kumar, Sangeet;Kaur, Jatinder
    • 호남수학학술지
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    • 제44권2호
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    • pp.179-194
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    • 2022
  • In the present study, we investigate generic lightlike submanifolds of indefinite nearly Kaehler manifolds. After proving the existence of generic lightlike submanifolds in an indefinite generalized complex space form, a non-trivial example of this class of submanifolds is discussed. Then, we find a characterization theorem enabling the induced connection on a generic lightlike submanifold to be a metric connection. We also derive some conditions for the integrability of distributions defined on generic lightlike submanifolds. Further, we discuss the non-existence of mixed geodesic generic lightlike submanifolds in a generalized complex space form. Finally, we investigate totally umbilical generic lightlike submanifolds and minimal generic lightlike submanifolds of an indefinite nearly Kaehler manifold.

GENERIC LIGHTLIKE SUBMANIFOLDS OF SEMI-RIEMANNIAN PRODUCT MANIFOLDS

  • Nand Kishor Jha;Jatinder Kaur;Sangeet Kumar;Megha Pruthi
    • 대한수학회논문집
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    • 제38권3호
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    • pp.847-863
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    • 2023
  • We introduce the study of generic lightlike submanifolds of a semi-Riemannian product manifold. We establish a characterization theorem for the induced connection on a generic lightlike submanifold to be a metric connection. We also find some conditions for the integrability of the distributions associated with generic lightlike submanifolds and discuss the geometry of foliations. Then we search for some results enabling a generic lightlike submanifold of a semi-Riemannian product manifold to be a generic lightlike product manifold. Finally, we examine minimal generic lightlike submanifolds of a semi-Riemannian product manifold.

명령어 주소 엔트로피 값을 이용한 실행 압축 해제 방법 연구 (A Study on Generic Unpacking using Entropy of Opcode Address)

  • 이원래;김형중
    • 디지털콘텐츠학회 논문지
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    • 제15권3호
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    • pp.373-380
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    • 2014
  • 악성코드는 분석가가 탐지 및 분석을 어렵게 하기 위하여 실행 압축 기술을 이용하고 있다. 최근에는 실행 압축 기술이 적용된 코드에 대응하기 위하여 실행 압축 기술에 대한 연구가 진행되고 있다. 실행 압축 기술은 압축된 실행코드를 해제해야 동작이 가능하여 실행 코드를 압축하는 과정에서 반복되는 코드를 이용한다. 따라서 일반 코드와 비교하여 반복되는 코드가 많아서 동일한 코드가 유사한 주소 값을 가지고 수행되는 특성이 있다. 코드영역을 일정한 영역으로 구분하면 실행 압축이 해제되는 코드는 원래의 코드와 비교하여 낮은 엔트로피값을 갖는다. 이를 이용하면 실행 압축 알고리즘을 알지 못한 상태에서 실행 압축 여부를 판단할 수 있으며 실행 압축코드를 해제할 수 있다. 본 논문에서는 압축이 해제되는 코드에서 명령어의 주소 값이 작은 엔트로피값을 갖는다는 것을 이용하여 실행압축을 해제하는 방법을 제안한다.