• Information Systems Review
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• v.24 no.4
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• pp.23-40
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• 2022

Although Support Vector Machine(SVM) has been used in various fields such as bankruptcy prediction model, the hyperplane learned by SVM in class imbalance problem can be severely skewed toward minority class and has a negative impact on performance because the area of majority class is expanded while the area of minority class is invaded. This study proposed optimized uneven margin SVM(OPT-UMSVM) combining threshold moving or post scaling method with UMSVM to cope with the limitation of the traditional even margin SVM(EMSVM) in class imbalance problem. OPT-UMSVM readjusted the skewed hyperplane to the majority class and had better generation ability than EMSVM improving the sensitivity of minority class and calculating the optimized performance. To validate OPT-UMSVM, 10-fold cross validations were performed on five sub-datasets with different imbalance ratio values. Empirical results showed two main findings. First, UMSVM had a weak effect on improving the performance of EMSVM in balanced datasets, but it greatly outperformed EMSVM in severely imbalanced datasets. Second, compared to EMSVM and conventional UMSVM, OPT-UMSVM had better performance in both balanced and imbalanced datasets and showed a significant difference performance especially in severely imbalanced datasets.

• Journal of The Korean Association For Science Education
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• v.27 no.1
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• pp.93-104
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• 2007

The purpose of this study is to investigate brain activity both during the processing of a scientific hypothesis about biological phenomena and mental arithmetic using 3.0T fMRI at the KAIST. For this study, 16 healthy male subjects participated voluntarily. Each subject's functional brain images by performing a scientific hypothesis task and a mental arithmetic task for 684 seconds were measured. After the fMRI measuring, verbal reports were collected to ensure the reliability of brain image data. This data, which were found to be adequate based on the results of analyzing verbal reports, were all included in the statistical analysis. When the data were statistically analyzed using SPM2 software, the scientific hypothesis generating process was found to have independent brain network different from the mental arithmetic process. In the scientific hypothesis process, we can infer that there is the process of encoding semantic derived from the fusiform gyrus through question-situation analysis in the pre-frontal lobe. In the mental arithmetic process, the area combining pre-frontal and parietal lobes plays an important role, and the parietal lobe is considered to be involved in skillfulness. In addition, the scientific hypothesis process was found to be accompanied by scientific emotion. These results enabled the examination of the scientific hypothesis process from the cognitive neuroscience perspective, and may be used as basic materials for developing a learning program for scientific hypothesis generation. In addition, this program can be proposed as a model of scientific brain-based learning.

• Korean Journal of Agricultural and Forest Meteorology
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• v.20 no.1
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• pp.73-87
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• 2018

A variety of micro meteorological variables such as air temperature, wind, solar radiation and latent heat at Gwangneung forests (conifer and broadleaved forests) and AWS (Automated Weather Station) of Pocheon urban area were used to quantify the air temperature reduction effect of forests, which is considered to be an eco-friendly solution for reducing the urban heat island intensity during summer. In June, July and August of 2016 and 2017, the average maximum air temperature differences between above and below canopy of forests, and between the forests and urban areas were $-1.9^{\circ}C$ and $-3.4^{\circ}C$ respectively, and they occurred at 17:00. However, there was no difference between conifer and broadleaved forests. The effect of air temperature reduction by the forests was positively correlated with accumulated evapotranspiration and solar radiation from 14:00 to 17:00 and showed a negative correlation with wind speed. We have developed a model to quantify the effect of air temperature reduction by forests using these variables. The nighttime air temperature reduction effect by forests was due to the generation of cold air from radiative cooling and the air temperature inversion phenomenon that occurs when the generated cold air moves down the side of mountain. The model was evaluated in Seoul by using 28 AWSs. The evaluation shows that the air temperature of each district in Seoul was negatively correlated with the area and size of the surrounding tall vegetation that drives vegetation evapotranspiration during the day. During the night, however, the size of the surrounding tall vegetation and the elevations of nearby mountains were the main influencing factors on the air temperature. Our research emphasizes the importance of the establishment and management of urban forests and the composition of wind roads from mountains for urban air temperature reduction.

• The korean journal of orthodontics
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• v.33 no.6 s.101
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• pp.485-497
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• 2003

The form and function of the craniofacial structure critically depend on genetic information. With recent advances in the molecular technology, genes that are important for normal growth and morphogenesis of the craniofacial skeleton are being rapidly uncovered, shaping up modem craniofacial biology. One of them is fibroblast growth factor receptor 2 (FGFR2). Specific point mutations in the. FGFR2 gene have been linked to Apert syndrome, which is characterized by premature closure of cranial sutures and craniofacial anomalies as well as limb deformities. To study pathogenic mechanisms underlying craniosynostosis phenotype of Apert syndrome, we used a transgenic approach; an FGFR2 minigene construct containing an Apert mutation (a point mutation that substitute proline at the position 253 to arginine; P253R) was introduced into fertilized mouse germ cells by DNA microinjection. The injected cells were then allowed to develop into transgenic mice. We used a bone-specific promoter (a DNA fragment from the type I collagen gene) to confine the expression of mutant FGFR2 gene to the bone tissue, and asked whether expression of mutant FGFR2 in bone is sufficient to cause the craniosynostosis phenotype in mice. Initial characterization of these mice shows prematurely closed cranial sutures with facial deformities expected from Apert patients. We also demonstrate that the transgene produces mutant FGFR2 protein with increased functional activities. Having this useful mouse model, we now can ask questions regarding the role of FGFR2 in normal and abnormal development of cranial bones and sutures.

• Korean journal of applied entomology
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• v.46 no.1 s.145
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• pp.37-42
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• 2007

To construct a life table and development model Schizaphis graminum (Rondani), its adult longevity and fecundity were studied at various constant temperatures ranging from 15 to $32.5^{\circ}C$, with $65{\pm}5%$ RH, and a photoperiod of 16L:8D. Adult longevity of the greenbug gradually increased with decreasing temperature below $32.5^{\circ}C$. Total fecundity was not significantly different at all temperatures except at $32.5^{\circ}C$. Daily fecundity gradually increased from $25.0^{\circ}C$. It was 3.6 at $27.5^{\circ}C$ and as temperatures either went down or up, it decreased to 1.4 at $15.0^{\circ}C$ and 0.4 at $32.5^{\circ}C$ Net reproduction rate (Ro) was highest with 47.6 at $25.0^{\circ}C$. The intrinsic rate of increase per day $(r_m)$ and the finite rate of increase per day $({\lambda})$ were highest with 0.4 and 1.5 at $30.0^{\circ}C$, respectively and the doubling time (Dt) was shortest with 0.98 at $32.5^{\circ}C$. The mean generation time (T) was 8.41 at $30.0^{\circ}C$.

• Journal of the Korean Association of Geographic Information Studies
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• v.12 no.1
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• pp.64-72
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• 2009

The method to generate a digital elevation model(DEM) from contour lines causes a problem in which the low relief landform cannot be clearly presented due to the fact that it is significantly influenced by the expression of micro landform elements according to the interval of contours. Thus, this study attempts to develop a landcover burning method that recovers the micro relief landform of the DEM, which applies buffering and map algebra methods by inputting the elevation information to the landcover. In the recovering process of the micro landform, the DEM was recovered using the buffering method and elevation information through the map algebra for the landcover element for the micro landform among the primary DEM generation, making landcover map, and landcover elements. The recovering of the micro landform was applied based on stream landforms. The recovering of landforms using the buffering method was performed for the bar, which is a polygonal element, and wetland according to the properties of concave/convex through generating contours with a uniform interval in which the elevation information applied to the recovered landform. In the case of the linear elements, such as bank, road, waterway, and tributary, the landform can be recovered by using the elevation information through applying a map algebra function. Because the polygonal elements, such as stream channel, river terrace, and artificial objects (farmlands) are determined as a flat property, these are recovered by inputting constant elevation values. The results of this study were compared and analyzed for the degree of landform expression between the original DEM and the recovered DEM. In the results of the analysis, the DEM produced by using the conventional method showed few expressions in micro landform elements. The method developed in this study well described wetland, bar, landform around rivers, farmland, bank, river terrace, and artificial objects. It can be expected that the results of this study contribute to the classification and analysis of micro landforms, plain and the ecology and environment study that requires the recovering of micro landforms around streams and rivers.

• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.6
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• pp.659-670
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• 2017

Oxidative stress and inflammation are key factors responsible for progression of liver injury. A variety of functions of oyster hydrolysate (OH) are affected by their antioxidant and anti-inflammatory activities. However, little is known regarding the effects of OH on a liver injury model. This study was performed to evaluate the effects of OH on acute liver injury induced by lipopolysaccharide/D-galactosamine (LPS/D-GalN) in mice. Experimental groups were divided into six groups as follows (each group, n=10): control (saline), LPS/D-GalN, LPS/D-GalN+OH (100 mg/kg), LPS/D-GalN+OH (200 mg/kg), LPS/D-GalN+OH (400 mg/kg), and LPS/D-GalN+silymarin (25 mg/kg, positive control). The experimental acute liver injury model was induced with LPS ($1{\mu}g/kg$) and D-GalN (400 mg/kg). We first analyzed antioxidant and anti-inflammatory activities in OH. OH showed high DPPH and ABTS radical scavenging activities and reduced ROS generation in Chang cells in a dose-dependent manner. In addition, OH showed anti-inflammatory activities, such as inhibition of cyclooxygenase-2 and 5-lipooxygenase. Treatment with OH down-regulated tumor necrosis factor $(TNF)-{\alpha}$, interleukin (IL)-6, and $IL-1{\alpha}$ expression levels in LPS-stimulated RAW264.7 cells. OH significantly reduced LPS/D-GalN-induced increases in the concentrations of alanine transaminase and aspartate aminotransferase in serum. In the LPS/D-GalN group, liver tissues exhibited apoptosis of hepatocytes with hemorrhages. These pathological alterations were ameliorated by OH treatment. Consistently, hepatic catalase activity was low in the LPS/D-GalN group compared to the control group, and catalase activity was significantly restored by OH treatment (P<0.05). Furthermore, OH markedly reduced the LPS/D-GalN-induced increase in $TNF-{\alpha}$, $IL-1{\beta}$, and IL-6 levels in liver tissue. Taken together, these results show that OH has hepatoprotective effects on LPS/D-GalN-induced acute liver injury via inhibition of oxidative stress and inflammation, suggesting that OH could be used as a health functional food and potential therapeutic agent for acute liver injury.

• Journal of Distribution Science
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• v.9 no.2
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• pp.131-140
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• 2011

On 1 July 2000, as the over-65 year-old population numbered 3,371,000 and accounted for over 7.1% of Korea's total population, an aging society was revealed. The over-65 percentage climbed to 11.0% by late 2010. A truly aged society is expected soon, by 2019. This aging society requires marketing research concerning the consumer behaviour and well-being of the elderly, because the 'silver generation' is emerging as a large part of the consumer market. The purpose of this study is to empirically analyse one effect among several satisfaction factors in the consuming cycle of various health functional products on consumer's well-being and the effect of product knowledge on the relationship between product satisfaction and well-being. To achieve this purpose, we established a research model after reviewing previous studies on product satisfaction, product knowledge, and consumer's well-being. The following hypotheses were developed from the research model. Hypothesis 1: When elderly consumers' satisfaction with health functional products increases, their well-being will increase. Hypothesis 2: The effect of their satisfaction with health functional products on their well-being will be strengthened according to the level of their knowledge of the products. Those hypotheses were tested by multiple and moderated regressions to the empirical data through a questionnaire survey. As a result, Hypothesis 1 was totally adopted, and Hypothesis 2 was only partially adopted. The study has many practical implications for well-being marketing. First, in order to heighten the elderly consumer's well-being, the level of his or her satisfaction with the health functional products has to be raised in every stage: during the acquisition, preparation, use, maintenance, and disposition of the consumption cycle. Moreover, promoting positive emotional experiences while diminishing negative ones requires effort because a consumer's well-being is made up of various needs. Second, the marketing of health functional products should be invigorated in order to raise the level of elderly consumers' knowledge of them. In other words, it is important to give them an expertise in the health functional products through different channels. A statistical analysis showed, however, that their knowledge has a decisive effect on only two satisfaction stages, preparation and maintenance. Nevertheless, this merely confirmed the intuitive assumption that the knowledge of health functional products is most relevant to their preparation and maintenance. In conclusion, this study is timely because few empirical studies exist on the relationships between silver consumer behaviour and well-being marketing. It contributes to our understanding of this subject by revealing the causality between the silver consumer's satisfaction and his or her well-being in the consumption cycle and by discovering the moderating influence of knowledge in that process.

• Journal of Korean Society of Forest Science
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• v.89 no.5
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• pp.655-665
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• 2000

Taking account of the structural variation on species composition by topography, the successional trends were comparatively analyzed for the three topographic positions (valley, mid-slope, and ridge) in the natural deciduous forest of Mt. Chumbong area. The analysis was based upon the subsequent process of generation replacement by understory saplings and seedlings over the overstory trees which will be eventually fallen down. This study adopted the plot sampling method, establishing twenty $20m{\times}20m$ quadrats and collecting vegetation and site data on each different topographic position. The transition matrix model, which was modified from the mathematical theory of Markov chain, was employed to analyze the successional trends and thereafter to predict the overstory species composition in the future for each different topographic position. In valley, the simulation indicated the remarkable decrease in the proportion of species composition of present dominants Quercus mongolica and Fraxinus mandshurica from current 23% and 21% to around 4% of each at the steady state, which is predicted to take less than 200 years. On the other hand, the proportion of such species as Abies holophylla, Acer mono, Tilia amurensis, and Ulmus laciniata will increase at the steady state. In mid-slope, the result showed the remarkable decrease in the proportion of Juglans mandshurica, Kalopanax pictus, and Tilia amurensis from current 15%, 8%, and 15% to 2%, 1%, and 5%, respectively, at steady state predicted to take more than 250 years. In ridge, the current dominant Quercus mongolica was predicted to be decreased dramatically from 58% to 8% at steady state which could be achieved about 200 years. On the contrary, the proportion of Acer mono and Tilia amurensis will be increased from current 4% and 3% to more than 20% and 40%, respectively, at the steady state. Overall results suggested that the study forest is more likely seral rather than climax community. Even though a lot of variation is inevitable due to various kinds of site and vegetation development, the study forest is considered to be more than 200 years away from the steady state or climax in terms of overstory species composition.

• Korean journal of applied entomology
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• v.53 no.4
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• pp.449-456
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• 2014

Life table analysis and temperature-dependent development experiments were conducted to understand the biological characteristics of the cabbage aphid, Brevicoryne brassicae (Linnaeus) on detached Tah Tsai Chinese cabbage (Brassica campestris var. narinosa) leaves at seven constant temperatures (15, 18, 21, 24, 27, 30 and $33{\pm}1^{\circ}C$; $65{\pm}5%$ RH; 16L:8D). Mortality was lowest at $24^{\circ}C$ with 18% and 0% at $1^{st}{\sim}2^{nd}$ and $3^{rd}{\sim}4^{th}$ nymphal stages, respectively. The developmental period of $1^{st}{\sim}2^{nd}$ nymphal stage was 8.4 days at $18^{\circ}C$, and it decreased with increasing temperature. The developmental period of the $3^{rd}{\sim}4^{th}$ nymphal stage was 6.7 days at $18^{\circ}C$. The lower threshold temperature calculated using a linear model was $7.8^{\circ}C$, and the effective accumulative temperature was 120.1DD. Adult longevity was 14.9 days at $21^{\circ}C$, and total fecundity was observed 58.5 at $24^{\circ}C$. According to the life table, the net reproduction rate was 47.5 at $24^{\circ}C$, and the intrinsic rate of increase and the finite rate of increase were 0.36 and 1.43, respectively, at $27^{\circ}C$. The doubling time was 1.95d at $27^{\circ}C$, and mean generation time was 7.43d at $30^{\circ}C$.