• Clinical Nutrition Research
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• 제12권3호
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• pp.199-217
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• 2023

People with higher genetic predisposition to obesity are more susceptible to cardiovascular diseases (CVDs) and healthy plant-based foods may be associated with reduced risks of obesity and other metabolic markers. We investigated whether healthy plant-foods-rich dietary patterns might have inverse associations with cardiometabolic risk factors in participants at genetically elevated risk of obesity. For this cross-sectional study, 377 obese and overweight women were chosen from health centers in Tehran, Iran. We calculated a healthy plant-based diet index (h-PDI) in which healthy plant foods received positive scores, and unhealthy plant and animal foods received reversed scores. A genetic risk score (GRS) was developed based on 3 polymorphisms. The interaction between GRS and h-PDI on cardiometabolic traits was analyzed using a generalized linear model (GLM). We found significant interactions between GRS and h-PDI on body mass index (BMI) (p = 0.02), body fat mass (p = 0.04), and waist circumference (p = 0.056). There were significant gene-diet interactions for healthful plant-derived diets and BMI-GRS on high-sensitivity C-reactive protein (p = 0.03), aspartate aminotransferase (p = 0.04), alanine transaminase (p = 0.05), insulin (p = 0.04), and plasminogen activator inhibitor 1 (p = 0.002). Adherence to h-PDI was more strongly related to decreased levels of the aforementioned markers among participants in the second or top tertile of GRS than those with low GRS. These results highlight that following a plant-based dietary pattern considering genetics appears to be a protective factor against the risks of cardiometabolic abnormalities.

• 한국전자통신학회논문지
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• 제13권3호
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• pp.633-642
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• 2018

태양광발전소는 급속한 보급을 거듭하며 민간 중심의 부동산 개발과 함께 건물의 부대시설 및 토지, 산악지역과 염전 부지 등 다양한 형태로 수익화 운영을 지속하고 있다. 최근의 태양광발전소는 발전단가의 하락에도 불구하고 주요 설비의 가격 대중화와 기술의 안정화로 발전소 구축이 다시 활발해지고 있다. 그러나 시공에 대한 비용투자와 발전소 운영 수익의 손익분기를 바탕으로 전통적인 부동산 자산 운용과의 수익성 비교검토는 부족한 실정으로 본 논문에서는 부동산 자산운용의 보편화된 형태로 오피스텔과 상가 투자를 바탕으로 태양광 발전시스템의 경제성을 분석하기 위한 검토와 연구를 진행 하였다.

• 한국해양공학회지
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• 제26권1호
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• pp.70-77
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• 2012

In this study, a numerical analysis of offshore installation using a floating crane with heave compensator is carried out in time domain. The motion analysis of crane vessels is based on floating body dynamics using convolution integral and the crane wire is treated as simple spring. The lifted structure is assumed as a rigid body with 3 degree-of-freedom translational motion. The heave compensator is numerically modelled by the generalized spring-damper system. Firstly, forced motion simulations of crane wire system are carried out to figure out the basic principle of heave compensator. The transfer function of crane wire system is obtained and effective wave period of heave compensator are found. Then, coupled analysis of crane vessel, crane wire, and lifted structure are performed in regular and irregular sea conditions. Two different crane vessels and two lifted structures (suction pile and manifold) are considered in this study. Through a series of numerical calculations, the effective zone of heave compensator is investigated with respect to wave period and crane wire length.

• 한국CDE학회논문집
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• 제21권3호
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• pp.334-340
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• 2016

As Information Technology (IT) is developed constantly, big data is becoming important in various industries, including ship and offshore industry where a lot of data are being generated. However, it is difficult to apply big data to ship and offshore industry because there is no generalized platform for its application. Therefore, this study presents a big data platform based on the Hadoop for applications in ship and offshore industry. The Hadoop is one of the most popular big data technologies. The presented platform includes existing data of shipyard and is possible to manage and process the data. To check the applicability of the platform, it is applied to estimate the weight of offshore plant topsides. The result shows that the platform can be one of alternatives to use effectively big data in ship and offshore industry.

• 한국시뮬레이션학회논문지
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• 제13권2호
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• pp.13-21
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• 2004

The thermal-hydraulic model ARTS which was based on the RETRAN-3D code adopted in the domestic full-scope power plant simulator which was provided in 1998 by KEPRI. Since ARTS is a generalized code to model the components with control volumes, the smaller time-step size should be used even if converged solution could not get in a single volume. Therefore, dedicated models which do not force to reduce the time-step size are sometimes more suitable in terms of a real-time calculation and robustness. In the case of PRT(Pressurizer Relief Tank) model, it is consist of subcooled water in bottom and non-condensable gas in top. The sparger merged under subcooled water enhances condensation. The complicated thermal-hydraulic phenomena such as condensation, phase separation with existence of non-condensable gas makes difficult to simulate. Therefore, the PRT volume can limit the time-step size if we model it with a general control volume. To prevent the time-step size reduction due to convergence failure for simulating this component, we developed a dedicated model for PRT. The dedicated model was expected to provide substantially more accurate predictions in the analysis of the system transients. The results were resonable in terms of accuracy, real-time simulation, robustness and education of operators, complying with the ANSI/ANS-3.5-1998 simulator software performance criteria and RETRAN-3D results.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2020년도 추계국제학술대회
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• pp.14-14
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• 2020

In December 2019, the COVID-19 epidemic was discovered in Wuhan, China, and since has disseminated around the world impacting human health for millions. Herein, in-silico drug discovery approaches were utilized to identify potential candidates as Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) main protease (M^pro) inhibitors. We investigated several databases including natural and natural-like products (>100,000 molecules), DrugBank database (10,036 drugs), major metabolites isolated from daily used spices (32 molecules), and current clinical drug candidates for the treatment of COVID-19 (18 drugs). All tested compounds were prepared and screened using molecular docking techniques. Based on the calculated docking scores, the top ones from each project under investigation were selected and subjected to molecular dynamics (MD) simulations followed by molecular mechanics-generalized Born surface area (MM-GBSA) binding energy calculations. Combined long MD simulations and MM-GBSA calculations revealed the potent compounds with prospective binding affinities against M^pro. Structural and energetic analyses over the simulated time demonstrated the high stabilities of the selected compounds. Our results showed that 4-bis([1,3]dioxolo)pyran-5-carboxamide derivatives (natural and natural-like products database), DB02388 and Cobicistat (DB09065) (DrugBank database), salvianolic acid A (spices secondary metabolites) and TMC-310911 (clinical-trial drugs database) exhibited high binding affinities with SARS-CoV-2 M^pro. In conclusion, these compounds are up-and-coming anti-COVID-19 drug candidates that warrant further detailed in vitro and in vivo experimental estimations.

• The Korean Journal of Ecology
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• 제28권1호
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• pp.31-36
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• 2005

본 연구는 대구광역시 권역 내의 노상식생에 대하여 군락분류를 수행하고, 분류된 식생 유형에 대한 생태적 분포 특성을 규명하였다. 총 50 개의 식물사회학적 식생자료를 이용하여 Z.-M. 학파의 군락분류법이 수행되었으며, 주좌표분석법(PCoA)에 의하여 식물군락의 분포 특성을 분석하였다. 대구지역의 노상식생은 5 개의 식물군락(그령군락, 질경이군락, 왕바랭이군락, 강아지풀군락, 바랭이군락)으로 구분되었으며, 광엽형 노상식생은 질경이군락뿐으로 화본형 노상식생형이 우세한 것으로 밝혀졌다. 노상식생의 서식처는 토양환경조건의 안정성과 수분조건에 의하여 안정-적습, 불안정-적습, 안정-건조, 불안정-건조의 네 가지 분할로부터 각 식생유형과 대응되었다. 노상식생에서 가장 높은 상대기여도를 나타내는 출현종은 바랭이, 왕바랭이, 그령, 질경이, 돌피, 토끼풀, 마디풀, 강아지풀, 금강아지풀, 쑥 순으로 나타났다. 특히 몬순 이후에 화기(花期)를 가지는 바랭이, 왕바랭이, 그령 등이 상대기여도 50% 이상의 수준을 보이는 사실이 특기되었다. 대구 노상식생의 특성은 대구생물기후구와 한반도의 $C_4$식물계절(후몬순계절), 그리고 일본 및 동아시아의 노상식생 최상급단위로 제창된 질경이군목과의 식생학적 차별성 등으로 정의되었다.

• International Journal of Precision Engineering and Manufacturing
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• 제3권2호
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• pp.15-21
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• 2002

A control-structure combined optimal design problem is discussed taking a 3-D truss structure as a design object. We use descriptor forms for a controlled object and a generalized plant because the structural parameters appear naturally in these farms. We consider not only minimum weight design problem for structure system, but also suppression problem of the effect of disturbances for control system as the purpose of the design. A numerical example shows the validity of combined optimal design of structure and control systems. We also consider the validity of sensor-actuator collocation for control system design in this paper.

• 안보군사학연구
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• 통권1호
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• pp.311-343
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• 2003

In this paper, we propose a generalized disturbance torque suppression control scheme of servo motors for missile fin actuators. Our controller consists of both a model based feed-forward controller and a stabilizing feedback controller. The feed-forward controller is designed such that the output of nominal plant tracks perfectly the reference position command with a desired dynamic characteristics. The feedback controller stabilizes the overall closed loop system. Furthermore, the feedback controller contains a free function that can be chosen arbitrary. The free function can be designed so as to achieve both the suppression of disturbances and the robustness to model uncertainties. In order to illuminate the superior performance of our control scheme to the conventional ones, we present some simulation results.

• 제어로봇시스템학회논문지
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• 제10권2호
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• pp.192-196
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• 2004

A combined optimal design problem is discussed taking a 3-D truss structure as a design object. We use descriptor forms for a controlled object and a generalized plant because the structural parameters appear naturally in these forms. We consider not only the minimum weight design problem for the structure, but also the suppression problem of the effect of disturbances for the control system as the purpose of the design. A numerical example shows the validity of combined optimal design of the structure and control systems. We also consider the validity of the sensor-actuator collocation for the control system design in this paper.