• The Korean Journal of Nuclear Medicine Technology
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• v.16 no.1
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• pp.96-101
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• 2012

Purpose: Glomerular filtration rate is an important index for assessment of renal function, early discovery of renal disease, and progress observation of chronic renal disease patients. In the present study, the objective is to conduct a comparative analysis of differences between Gates and Modified Gates method in dynamic renal scintigraphy based on MDRD (Modification of Diet Renal Disease) formula using blood collection. Materials and Methods: Renal scintigraphy was performed for 45 patients who visited our hospital between November 2010 and August 2011. For 20 patients of those tested, glomerular filtration rates from Gates method and MDRD formula using AGUS equipment, were compared. For the other 20 patients, glomerular filtration rates from Modified Gates method and MDRD formula using INFINIA equipment. Finally, Gates and Modified Gates method were compared for 5 patients who indicated no change in glomerular filtration rates from MDRD formula during progress observation. Results: Glomerular filtration rates from both Gates and Modified Gates method showed a high correlation with those from MDRD formula ($p$<0.01, r=0.903, r=0.867), with a paired difference mean for Gates method of $2.05{\pm}2.54mL/min/1.73m$, and that for Modified Gates method of $25.2{\pm}3.71mL/min/1.73m$. Finally, the values for Gates method and those for Modified Gates method showed a high correlation for the five patients ($p$<0.05, r=0.949), with a paired difference mean of $20.4{\pm}8.84mL/min/1.73m$. Conclusion: Glomerular filtration rates from Gates method, Modified Gates method and MDRD formula showed mutually high correlations. If the tests are performed with recognition for the correlations between Gates and Modified Gates method used in a dynamic renal scintigraphy, then an accurate assessment of renal function is considered possible with an improved diagnostic ability.

• Journal of radiological science and technology
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• v.46 no.5
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• pp.417-425
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• 2023

The glomerular filtration rate (GFR) has been the subject of much research as a key indicator for diagnosing, treating, and monitoring kidney function. The gamma camera method (Gates method) is simple and allows simultaneous acquisition of GFR and renal scintigraphy for each kidney, however its accuracy is inferior. This study aimed to investigate changes in GFR depending on how region of interest (ROI) are set up, which is one of many factors influencing accuracy. GFR was calculated by setting the ROI for each phase of the image acquisition time (Gates-1: 0~1 minutes, Gates-2: 1~3 minutes, Gates-3: 3~27 minutes), and statistical significance was verified based on probability value 0.05 through ANOVA analysis. While there was no statistically significant difference among results from Gates-1, 2, 3 (p=0.481>0.05), overall results from the Gates method tended to overestimate compared to those from the multiple blood sampling-dual exponential (MBSDE) method. When comparing averages between phases, results from Gates-2 were most similar to those from the MBSDE method. Moreover, paired t-test p-values between MBSDE method and phases were as follows Gates-1: 0.021 (p<0.05), Gates-2: 0.280 (p>0.05), and Gates-3: 0.164 (p>0.05) indicating that only Gates-1 had statistically significant differences compared with MBSDE method. Thus, setting ROI around 2~3 minutes is calculated can aid in accurately determining GFR when Gates Method.

• The Korean Journal of Nuclear Medicine
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• v.38 no.4
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• pp.306-310
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• 2004

Purpose: The aim was to assess how the background site affects the Gates' glomerular filtration rate(GFR) measurement using Tc-99m-DTPA in correlation with GFR by I-125-lothalamate method. Material and methods: The study populations were 63 adults with 39 men and 24 women aged from 20 to 59 yrs (mean=37.9 yrs). The fellowing five background regions of interest were used in measurement of GFR using Gates' method: 1) lower side of each kidney(subrenal), 2) around each kidney(circumferential), 3) upper side of each kidney(suprarenal), 4) lateral side of each kidney(lateral), 5) between the two kidneys(inter-renal). We also measured GFR using I-125-iothalamate in each subject. The two studies were separated by 1 to 3 weeks. The subjects were divided into two groups by renal depth. Group 1 with renal $depth{\geq}7cm$ and group 2 with renal depth<7cm. We calculated the means and standard deviations of the GFRs measured by two studies. And we statistically analyzed the correlation and differences among GFRs by Gates' method and the GFR by iothalamate method with correlation analysis. Results: The GFRs by Gates' method using suprarenal and inter-renal background correction showed better correlation with the GFR measured by I-125-iothalamate. And GFRs measured by Gates' method showed statistically significant correlation with the GFR measured by I-125-iothalamate in the group with renal depth<7cm. But GFRs measured by Gates' method did not show statistically significant correlation with the GFR measured by I-125-iothalamate in the group with renal $depth{\geq}7cm$. Conclusion: GFRs measured with Gates' method showed higher correlation with the GFR measured by I-125-iothalamate when the regions of interest were plated over the suprarenal and inter-renal backgrounds. And GFRs measured with Gates method showed statistically significant correlation with the GFR measured by I-125-iothalamate in the group with renal depth<7cm.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.10 no.9
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• pp.1538-1544
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• 2006

This paper proposes a non-systolic parallel $AB^2+C$ Computing unit based on irreducible AOP order m of $GF(2^m)$. Proposed circuit have only AND gates and EX-OR gates, composes of cyclic shift operation, multiplication operation power operation power-sum operation and addition operation using a merry irreducible AOP. Suggested operating a method have an advantage high speed data processing, low power and integration because of only needs AND gates and EX-OR gates. $AB^2+C$ computing unit has delay-time of $T_A+(1+[log^m_2])T_X$.

• The Korean Journal of Nuclear Medicine Technology
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• v.18 no.2
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• pp.48-56
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• 2014

Purpose $^{99m}Tc$-DTPA renal scintigraphy serves as a key indicator to measure a kidney donor's Glomerular Filtration Rate (GFR) and determine the possibility of kidney transplant. The Gates method utilized to measure GFR considers 3 variables of renal depth, injection dose, and net kidney counts. In this research, we seek to compare changes in kidney donors' GFR according to renal depth measurement methods of the 3 variables. Materials and Methods We investigated 32 kidney donors who had visited the hospital from October, 2013 to March, 2014 and received abdominal CT and $^{99m}Tc$-DTPA GFR examination. With the cross-section image of the CT and the lateral image from a gamma camera, we measured the renal depth and compared with renal depth calculation equations-Tonnesen, Taylor, and Itoh methods. Renal depth-specific GFR was calculated by using Xeleris Ver. 2.1220 of GE. Then the results were compared with MDRD (Modification of Diet Renal Disease) GFRs based on serum creatinine level. Results The renal depths measured based on the CT and gamma camera images showed high correlation. Tonessen equation gave the lowest GFR value while the value calculated by using the renal depth of CT image was the highest with a 16.62% gap. MDRD GFR showed no statistically significant difference among values calculated through Taylor, Itoh, CT and gamma camera renal depth application (P>0.05), but exhibited a statistically significant change in the value based on Tonnesen equation (P<0.05). Conclusion This research has found that, in GFR evaluation in kidney donors by utilizing $^{99m}Tc$-DTPA, Tonnesen equation-based Gates method underestimated the value than the MDRD GFR. Therefore, if a MDRD GFR value shows a huge difference from the actual examination value, using an image-based renal depth measurement, instead of Tonnesen equation applied to Gates method, is expected to give an accurate GFR value to kidney donors.

• The Journal of the Korea institute of electronic communication sciences
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• v.9 no.4
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• pp.447-454
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• 2014

Recently most of functional synthesis methods for quantum circuit realization have a tendency to adopt the declarative functional expression more suitable for computer algorithms, so it's difficult to analysis synthesized quantum functions. This paper presents a new functional representation of quantum circuits compatible with simple architecture and intuitive thinking. The proposal of this paper is a new functional synthesis development by using the control functions as the power of corresponding to affine-controlled quantum gates based on the mathematical substitution of serial-product matrix operation over the target line for the arithmetic and modulo-2 ones between power functions of unitary operators. The functional synthesis algorithm proposed in this paper is useful for the functional expressions and synthesis using both of reversible and irreversible affine-controlled NCV-quantum gates.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.13 no.3
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• pp.27-34
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• 2003

Recently, an efficient hardware development for a cryptosystem is concerned. The efficiency of a multiplier for GF($2^n$)is directly related to the efficiency of some cryptosystem. This paper, considering the trade-off between time complexity andsize complexity, proposes a new multiplier architecture having n[n/2] AND gates and n([n/2]+1)- $$\Delta$_n$ = XOR gates, where $$\Delta$_n$=1 if n is even, $$\Delta$_n$=0 otherwise. This size complexity is less than that of existing ${multipliers}^{[5][12]}$which are $n^2$ AND gates and $n^2$-1 XOR gates. While a new multiplier is a serial-parallel multiplier to output a result of multiplication of two elements of GF($2^n$) after 2 clock cycles, the suggested multiplier is more suitable for some cryptographic device having space limitations.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.32 no.5
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• pp.323-331
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• 2019

In this study, a computational model approach for the modeling of hydrodynamic pressures acting on radial gates during strong earthquakes is proposed. The use of the dynamic layering method with the Arbitrary Lagrangian Eulerian (ALE) algorithm and the SIMPLE method for simulating free reservoir surface flow in addition to moving boundary interfaces between the fluid domain and a structure due to earthquake excitation are suggested. The verification and validation of the proposed approach are realized by comparisons performed using the renowned formulation derived by the experimental results for vertical and inclined dam surfaces subjected to earthquake excitation. A parameter study for the truncated lengths of the two-dimensional fluid domain demonstrates that twice the water level leads to efficient and converged computational results. Finally, numerical simulations for large radial gates with different curvatures subjected to two strong earthquakes are successfully performed using the suggested computational model.

• Journal of Korea Water Resources Association
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• v.30 no.6
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• pp.649-659
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• 1997

The influence of polluted water discharged from the Saemankeum Lake is predicted by using two-dimensional finite element model. The simulation results show that influence of the Polluted water to the northern part of the Kckunsan Islands is small during flood time. The reason is because lock gates are located in the south of the Kokunsan Islands so that tidal current directing north is blocked by these Islands. However, during the ebb time, the influence of the polluted water is extended to the whole southern part of the Kokunsan Islands. When the amount of ten percent of the total volume of polluted water is discharged from the Saemankeum Lake, equi-concentration contour line of one tenth of initial discharge concentration includes the inner area surrounded by Sinsi Island, Munyeo Island, Bian Island, and Daehang-Li. In general, peak concentration near the lock gates is found out to be higher during the spring tide than the neap tide.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.31A no.6
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• pp.169-176
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• 1994

This paper describes an efficient parallel evaluation algorithm for accelerating fault simulation, which can be applied to combinational circuits. The method is based on a combination of all the advantages in parallel, deductive and concurrent schemes in terms of evaluation and propagation of fautly gates for achieving high performance and handling multi-valued signal. We also propose a new fault grouping procedure to increase parallel operation of fault bits by packing active faults which occur in the same signal line densely into the same fault group. The algorithm has been implemented in C language on a Sun 3/260, and experimental results for ISCAS'85 benchmark circuits have been shown that this algorithm is 2.6 to 8.2 times faster than the conventional cocurrent fault simulation algorithm.