• Korean Journal of Remote Sensing
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• v.36 no.6_3
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• pp.1711-1720
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• 2020

Particulate matter (PM) that has been artificially generated during the recent of rapid industrialization and urbanization moves and disperses according to weather conditions, and adversely affects the human skin and respiratory systems. The purpose of this study is to predict the PM10 concentration in Seoul using meteorological factors as input dataset for multiple linear regression (MLR), support vector machine (SVM), and random forest (RF) models, and compared and evaluated the performance of the models. First, the PM10 concentration data obtained at 39 air quality monitoring sites (AQMS) in Seoul were divided into training and validation dataset (8:2 ratio). The nine meteorological factors (mean, maximum, and minimum temperature, precipitation, average and maximum wind speed, wind direction, yellow dust, and relative humidity), obtained by the automatic weather system (AWS), were composed to input dataset of models. The coefficients of determination (R2) between the observed PM10 concentration and that predicted by the MLR, SVM, and RF models was 0.260, 0.772, and 0.793, respectively, and the RF model best predicted the PM10 concentration. Among the AQMS used for model validation, Gwanak-gu and Gangnam-daero AQMS are relatively close to AWS, and the SVM and RF models were highly accurate according to the model validations. The Jongno-gu AQMS is relatively far from the AWS, but since PM10 concentration for the two adjacent AQMS were used for model training, both models presented high accuracy. By contrast, Yongsan-gu AQMS was relatively far from AQMS and AWS, both models performed poorly.

• Journal of the Economic Geographical Society of Korea
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• v.25 no.1
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• pp.147-170
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• 2022

This article analyzes the spillover effects by dividing the weekly rate of return on apartment prices in 70 si-gun-gu (local area) in the Capital Region into three periods: the entire period (April 2008~August 2021); the period before the price surge (April 2008~October 2018); and the period of price surge (November, 2018~August 2021), based on a consideration of the cycle of fluctuations in apartment sales prices and the timing of the current government's policy interventions. The results obtained from this analysis are summarized as follows. First, the analysis of the spillover effects is similar to or different from the results of existing work depending on the period. The analysis of the spillover effects on the entire period and the period before the price surge shows that the 'Gangnam' effect exists in the apartment market in the Capital Region. On the other hand, the analysis of the spillover effects on the period of price surge reveals different results than before. The spillover effect index calculated through the analysis of the rolling sample decreases during the decline in the cycle of apartment sales prices, while the opposite trend is shown during the upward period. Looking at the timing between the peak of the spillover effect index and policy interventions, it appears that the government's policy interventions took place after the peak of the spillover effect index in 2017, before the peak in 2018 and 2019, and around or after the peak after 2020.

• Journal of the Korean Regional Science Association
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• v.38 no.1
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• pp.3-20
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• 2022

The purpose of this study is to exploratory analyze the transition pattern of establishments and workers in new growth industries in the metropolitan area from 2010 to 2019 and to identify regional factors affecting the inflow and outflow of new growth industry start-ups. As for the analysis, the original data of the Census on Establishments were used, and spatial data at the sigungu level were constructed based on the inflow and outflow data of the number of new growth industry businesses and workers. For the analysis, the degree centrality of connection to outflow inflow by region was calculated, and an empirical analysis was conducted on regional-level factors affecting the inflow and outflow of new growth industries by applying a negative binomial regression model. According to the results, the new growth industry manufacturing sector was actively relocated in southern Gyeonggi Province, and the new growth industry service sector in Gangnam and Guro-Geumcheon-gu, and the impact of regional-level factors on the inflow and outflow of new growth industry start-ups varies depending on the industry. This study presented implications for regional industrial policies to improve the competitiveness of the local economy by attracting new industries by identifying spatial transition patterns for new growth industries and conducting empirical analysis to identify influencing factors.

• Genomics & Informatics
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• v.20 no.3
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• pp.29.1-29.12
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• 2022

Several studies have shown associations between irinotecan toxicity and UGT1A genetic variations in colorectal and lung cancer, but only limited data are available for gastric cancer patients. We evaluated the frequencies of UGT1A polymorphisms and their relationship with clinicopathologic parameters in 382 Korean gastric cancer patients. Polymorphisms of UGT1A1*6, UGT1A1*27, UGT1A1*28, UGT1A1*60, UGT1A7*2, UGT1A7*3, and UGT1A9*22 were genotyped by direct sequencing. In 98 patients treated with irinotecan-containing regimens, toxicity and response were compared according to the genotype. The UGT1A1*6 and UGT1A9*22 genotypes showed a higher prevalence in Korean gastric cancer patients, while the prevalence of the UG1A1*28 polymorphism was lower than in normal Koreans, as has been found in other studies of Asian populations. The incidence of severe diarrhea after irinotecan-containing treatment was more common in patients with the UGT1A1*6, UGT1A7*3 and UGT1A9*22 polymorphisms than in controls. The presence of the UGT1A1*6 allele also showed a significant association with grade III-IV neutropenia. Upon haplotype and diplotype analyses, almost every patient bearing the UGT1A1*6 or UGT1A7*3 variant also had the UGT1A9*22 polymorphism, and all severe manifestations of UGT1A polymorphism-associated toxicity were related to the UGT1A9*22 polymorphism. By genotyping UGT1A9*22 polymorphisms, we could identify high-risk gastric cancer patients receiving irinotecan-containing chemotherapy, who would experience severe toxicity. When treating high-risk patients with the UGT1A9*22 polymorphism, clinicians should closely monitor them for signs of toxicity such as severe diarrhea or neutropenia.

• Journal of Digestive Cancer Reports
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• v.8 no.2
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• pp.81-90
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• 2020

We performed a comprehensive meta-analysis on whether Helicobacter pylori (H. pylori) eradication can prevent gastric cancer in individuals with precancerous lesions (chronic atrophic gastritis, intestinal metaplasia, and dysplasia). The studies evaluating the effect of H. pylori eradication on gastric cancer were searched from PubMed, KoreaMed, EMBASE, and Cochrane Library. Subgroup analyses by precancerous lesions, regions and follow-up time were performed. Six randomized clinical trials were included. In the overall population, H. pylori eradication significantly decreased the risk of gastric cancer (risk ratio [RR]=0.56; 95% confidence interval [CI]: 0.41-0.77, p<0.01). Eradication therapy significantly reduced the risk of gastric cancer in Asian and group who followed up more than 10 years (RR=0.51; 95% CI: 0.35-0.73, p<0.01; I²=0%, p=0.46). However, subgroup analysis according to the precancerous lesions did not show any significant results (p>0.05). In the general population especially in Asian population, H. pylori eradication can reduce the risk of gastric cancer. The effect of the eradication treatment is remarkable upon the long-term follow-up. In contrast, there is insufficient evidence whether the eradication should be recommended for the individuals with precancerous lesions.

• Journal of the Korean Regional Science Association
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• v.38 no.4
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• pp.31-44
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• 2022

This study was conducted with the aim of confirming the relevance and effect of the characteristics of the cities and cities in the neighborhood area, focusing on the sale price per square meter of apartment. Specifically, it was intended to determine whether cities in the relevant city and neighborhood area have differential characteristics between the metropolitan area and the non-metropolitan area, whether industrial characteristics, urban planning and development project characteristics, and location characteristics. Comparing the research results of the city and metropolitan area, it was found that there was a correlation in all areas of population characteristics. Industrial and urban planning projects and development project characteristics sectors are not significant in the city, but they appear significant when analyzed in the urban area of the year. When classifying and analyzing the metropolitan area and the non-metropolitan area, both the metropolitan area and the non-metropolitan area were significant in the population sector, and only the distance from Gangnam-gu was significant in the local sector. Since the population is concentrated in the Seoul metropolitan area now, the sale price per square meter of apartments is also concentrated in the Seoul metropolitan area, which is believed to result in such a result. This is judged to be an analysis that appears because the characteristics of the developable status of the metropolitan area and the non-metropolitan area are different. Accordingly, this study shows that the characteristics of neighboring areas as well as the city should be analyzed when analyzing the factors affecting the sale price per square meter of apartment, and suggests that housing market monitoring needs to be carried out together.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.39 no.6
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• pp.497-505
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• 2021

Due to recent underground space accidents, are a frequent occurence in Korea, the government established the basic plan for the construction of the IUGIM (Integrated Underground Geospatial Information Map) in 2015 as a measure for safety management of underground spaces. The development of IUGIM was partially completed as of 2021. The underground space management entity and related organizations are utilizing it. This study is being carried out as part of a plan to improve the usability of IUGIM, and to build a visualization system that compares real-time field data with stored data. A system, equipped with a visualization function for borehole data and 6 types of underground facilities built and managed on IUGIM; a tool capable of comparative analysis with real-time data measured in the field, is being built. The 6 types of underground facilities are water supply pipe, sewage pipe, power pipe, gas pipe, communication pipe, and heating pipe. The completed system was demonstrated at three locations in Seocho-gu, Gangnam-gu in Seoul. The field demonstration was carried out by accessing the mobile center and downloading IUGIM data, visualizing IUGIM data (surface creation, borehole information, underground facilities), and visualizing the GPR(Ground Penetrating Radar)-based data acquired at the field. As a result of the empirical results of IUGIM data and GPR-based field data, it was judged to be suitable. As a result of this study, it is judged that it can be helpful for safe construction at the excavation site.

• Korean Journal of Clinical Laboratory Science
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• v.55 no.1
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• pp.1-8
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• 2023

The purpose of this study is to find terms that can give identity to the major and occupation of clinical laboratory technologist (also known as medical technologist). The term clinical pathology includes all branches of pathology, namely anatomical pathology, chemical pathology, hematology, microbiology, and all respective subspecialties. Unfortunately, several countries exclude anatomical pathology from the term clinical pathology, a problem that gets compounded when the title is translated into languages other than English. Clinical pathology (US, UK) is a medical specialty. Similar terms are laboratory medicine (Germany, Poland), medical/clinical biology (France, Netherlands) or clinical analysis (Spain). Depending on the person questioned, medical technology is defined slightly differently by individuals, companies, and institutions. The definition also depends on the language in which the question is asked. Medical technology can be translated to define clinical laboratory technology, allied health sciences, medical equipment, biomedical engineering, and health technology. The terms 'clinical pathology technology and pathological technology' are not used in allied health sciences. The names of 'medical technology·medical technologist' can be replaced by 'biomedical laboratory science·biomedical laboratory technologist' or 'clinical laboratory analysis·clinical laboratory analyst'. In this study, it is proposed to change the name of academic and occupation to 'medical biology·medical biology technologist' that combines the term biomedical.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.21 no.6
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• pp.115-131
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• 2022

Carbon dioxide (CO₂) emissions from the transportation sector in South Korea accounts for 16.5% of all CO₂ emissions, and road transportation accounts for 96.5% of this sector's emissions in South Korea. Hence, constant research is being carried out on methods to reduce CO₂ emissions from this sector. With the emerging use of smart crossings, attempts to monitor individual vehicles are increasing. Moreover, the potential commercial deployment of autonomous vehicles increases the possibility of obtaining individual vehicle data. As such, CO₂ emission research was conducted at five signalized intersections in the Gangnam District, Seoul, using data such as vehicle type, speed, acceleration, etc., obtained from image detectors located at each intersection. The collected data were then applied to the MOtor Vehicle Emission Simulator (MOVES)-Matrix model-which was developed to obtain second-by-second vehicle activity data and analyze daily CO₂ emissions from the studied intersections. After analyzing two large and three small intersections, the results indicated that 3.1 metric tons of CO₂ were emitted per day at each intersection. This study reveals a new possibility of analyzing CO₂ emissions using actual individual vehicle data using an improved analysis model. This study also emphasizes the importance of more accurate CO₂ emission analyses.

• Journal of Periodontal and Implant Science
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• v.53 no.4
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• pp.306-317
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• 2023

Purpose: Biphasic calcium phosphate (BCP), a widely used biomaterial for bone regeneration, contains synthetic hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP), the ratio of which can be adjusted to modulate the rate of degradation. The aim of this study was to evaluate the clinical and radiographic benefits of reconstructing peri-implant bone defects with a newly developed BCP consisting of 60% β-TCP and 40% HA compared to demineralized bovine bone mineral (DBBM). Methods: This prospective, multicenter, parallel, single-blind randomized controlled trial was conducted at the periodontology departments of 3 different dental hospitals. Changes in clinical (defect width and height) and radiographic (augmented horizontal bone thickness) parameters were measured between implant surgery with guided bone regeneration (GBR) and re-entry surgery. Postoperative discomfort (severity and duration of pain and swelling) and early soft-tissue wound healing (dehiscence and inflammation) were also assessed. Data were compared between the BCP (test) and DBBM (control) groups using the independent t-test and the χ² test. Results: Of the 53 cases included, 27 were in the test group and 26 were in the control group. After a healing period of 18 weeks, the full and mean resolution of buccal dehiscence defects were 59.3% (n=16) and 71.3% in the test group and 42.3% (n=11) and 57.9% in the control group, respectively. There were no significant differences between the groups in terms of the change in mean horizontal bone augmentation (test group: -0.50±0.66 mm vs. control groups: -0.66±0.83 mm, P=0.133), postoperative discomfort, or early wound healing. No adverse or fatal complications occurred in either group. Conclusions: The GBR procedure with the newly developed BCP showed favorable clinical, radiographic, postoperative discomfort-related, and early wound healing outcomes for peri-implant dehiscence defects that were similar to those for DBBM.