• Journal of Korean Association for Spatial Structures
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• v.15 no.1
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• pp.75-84
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• 2015

This paper presents the dimensionless wall distance, y+ effect on SST turbulent model for wind turbine blade. The National Renewable Energy Laboratory (NREL) Phase VI wind turbine was used for the study, which the wind tunnel and structural test data has publicly available. The near wall treatment and turbulent characteristics have important role for proper CFD simulation. Most of the CFD development in this area is focused on advanced turbulence model closures including second moment closure models, and so called Low-Reynolds (low-Re) number and two-layer turbulence models. However, in many cases CFD aerodynamic predictions based on these standard models still show a large degree of uncertainty, which can be attributed to the use of the $\epsilon$-equation as the turbulence scale equation and the associated limitations of the near wall treatment. The present paper demonstrates the y+ definition effect on SST (Shear Stress Transport) turbulent model with advanced automatic near wall treatment model and Gamma theta transitional model for transition from lamina to turbulent flow using commercial ANSYS-CFX. In all cases the SST model shows to be superior, as it gives more accurate predictions and is less sensitive to grid variations.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2011.04a
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• pp.602-605
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• 2011

본 논문에서는 마찰감쇠기가 설치된 건물이 붕괴하중을 받을 때의 에너지소산능력을 고려하여 등가감쇠비를 유도하였다. 마찰감쇠기는 주로 지진과 같은 수평하중에 대한 에너지를 소산하기위해 설치된다. 마찰감쇠기를 대각 가새형으로 설치하면 수평하중에 대한 저항력뿐 만아니라 수직하중에 대한 저항성능도 발휘된다. 건물에 설치된 마찰감쇠기는 외력의 크기에 따라 정지와 운동의 상태를 반복하여 외부 입력에너지를 소산시키기 때문에 외력과 응답관계가 비선형이다. 건물은 고유의 점성감쇠를 가지므로 마찰감쇠기가 설치된 건물은 마찰과 점성감쇠를 동시에 고려해야하므로 해석적인 정해를 구하기가 어렵다. 에너지 평형을 이용하여 등가감쇠비를 구하고 운동방정식을 등가선형화하면 쉽게 저항 성능을 파악할 수 있다. 우선 건물에 영향을 미치는 것은 감쇠이므로 감쇠의 영향력을 마찰력비, ${\gamma}_c$로 나타내었다. 둘째, 정해를 마찰력비로 표현하여 유도하고 응답특성을 파악하였다. 셋째, 에너지 균형식을 통해 등가감쇠비를 산정하였다. 마지막으로 등가감쇠비를 검증하기 위하여 등가감쇠비를 이용하여 등가선형화한 응답과 실제 마찰감쇠기를 설치하여 비선형 수치해석한 결과와 비교, 검증하였다.

• Journal of Sasang Constitutional Medicine
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• v.29 no.2
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• pp.154-173
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• 2017

Objectives This study was conducted to evaluate the effects of Yeoldahanso-tang on obesity in rats induced by high fat diet experimentally. Methods The experiment was conducted with rats divided into 5 groups. Rats were evaluated for change of weight, hematologic and serum biochemical parameters. Results Yeoldahanso-tang group showed significant reductions in FER, body weight, adipose tissue weight and size. The level of Creatinine, glucose, ALP, T-cholesterol, Triglyceride, LDL-cholesterol, Leptin and IGF-1 of Yeoldahanso-tang group was significantly lower than those in HFD-CTL group. The level of HDL-cholesterol, free fatty acid and Adiponectin in Yeoldahanso-tang group was significantly higher than those in HFD-CTL group. As compared with HFD-CTL group, AMPK-${\alpha}1$, UCP2 and adiponectin mRNA in liver of Yeoldahanso-tang group were significantly increased and AP2/FABP4, AMPK-${\alpha}2$ and PPAR-${\gamma}$ mRNA in liver of Yeoldahanso-tang group was significantly decreased. Conclusion These results suggest that Yeoldahanso-tang has inhibitory effects on obesity in high fat diet induced obese mice.

• Proceedings of the Korean Information Science Society Conference
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• 2005.11b
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• pp.913-915
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• 2005

임의의 영상에서 얼굴을 검출하는 것은 얼굴을 인식하는데 있어서 선행되어야 할 필수과정이다. 본 논문은 조명의 변화가 심한 컬러영상에서 얼굴을 검출하는 것을 목적으로 한다. 본 논문은 기존의 기하학적 밝기분포 마스크만을 사용한 방법이 조명 변화에 취약한 단점을 보완하는데 중점을 두었다. 히스토그램 평활화(Histogram Equalization : HE)와 감마 크기 보정 (Gamma Intensity Correction : GIC) 방법을 이용해서 조명에 대한 간섭을 줄인 후, 영상 전체에서 피부 영역을 추출하고 이어서 눈 후보들을 검출한다. 검출된 눈 후보들로부터 기하학적 밝기분포 마스크를 적용하여 효과적으로 얼굴 후보들을 찾을 수 있고, 이렇게 찾아진 얼굴 후보들은 주성분분석법(Principal Component Analysis : PCA)를 이용해서 얼굴인지 여부를 판별하게 된다. 본 알고리즘은 조명 밝기 등으로 인해 검출률이 떨어졌던 단점을 보완할 수 있었고, 향후 얼굴 검출 분야에 있어서도 활용 가치가 있을 것으로 생각된다.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.29 no.3
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• pp.105-110
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• 2017

Underfloor air distribution (UFAD) is an air distribution strategy for providing ventilation and space conditioning in buildings. UFAD systems use the underfloor plenum beneath a raised access floor to provide conditioned air through floor diffusers that create a vertical thermal stratification during cooling operations. Thermal stratification has significant effects on energy, indoor air quality, and thermal comfort performance. The purpose of this study was to characterize the influence of a linear bar grille diffuser on thermal stratification in both interior and perimeter zones by developing Gamma-Phi based prediction models. Forty-eight simulations were carried out using a Computational Fluid Dynamics (CFD) technique. The number of diffusers, the air flow supply, internal heat gains, and solar radiations varied among the different cases. Models to predict temperature stratification for the tested linear bar grille diffuser have been developed, which can be directly implemented into dynamic whole-building simulation software such as EnergyPlus.

• Journal of the Korean Society of Propulsion Engineers
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• v.10 no.2
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• pp.1-14
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• 2006

Present study examines the numerical issues of cell structure simulation for various regimes of detonation phenomena ranging from weakly unstable to highly unstable detonations. Inviscid fluid dynamics equations with $variable-{\gamma} $ formulation and one-step Arrhenius reaction model are solved by a MUSCL-type TVD scheme and 4th order accurate Runge-Kutta time integration scheme. A series of numerical studies are carried out for the different regimes of the detonation phenomena to investigate the computational requirements for the simulation of the detonation wave cell structure by varying the reaction constants and grid resolutions. The computational results are investigated by comparing the solution of steady ZND structure to draw out the minimum grid resolutions and the size of the computational domain for the capturing cell structures of the different regimes of the detonation phenomena.

• Journal of KIISE:Computer Systems and Theory
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• v.31 no.9
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• pp.495-502
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• 2004

A rapid growth of the Internet user and rich media content cause an excessive server load and high network traffic, and thus it decreases the quality of service. A solution to this problem is to distribute the content on multiple replicated servers. However, in this circumstance, clients face additional task of selecting the best server to provide proper so${\gamma}$vice which clients request. This paper is intended to propose an adaptive server selection mechanism for a client request based on distance and server load. This will offer a fast and scalable service in response to the increase of massive and realtime multimedia content and contribute to floating a new business model of digital content service.

• Journal of Life Science
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• v.23 no.6
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• pp.812-824
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• 2013

Reserpine, an anti-hypertensive drug, is able to positively modulate several phenotypes associated with $A{\beta}$ toxicity in a Caenorhabditis elegans model of Alzheimer's disease (AD). We investigated into the therapeutic effects of reserpine on mammalian neurodegenerative disorders, and found that significant alteration of the key factors influencing AD was detected in Tg2576 mice after reserpine treatment for 30 days. The aggressive behavior of Tg2576 mice was significantly improved upon reserpine treatment, whereas their social contact was consistently maintained. Furthermore, the levels of $A{\beta}$-42 peptide in the hippocampus of the brain and blood serum were lower in the reserpine-treated group than in the vehicle-treated group. Among g-secretase components, the expression levels of PS-2, Pen-2, and APH-1 were slightly lower in reserpine-treated Tg2576 mice, although a significant change in nicastrin (NCT) expression was not detected. Furthermore, the serum level of nerve growth factor (NGF) increased in reserpine-treated Tg2576 mice compared with vehicle-treated mice. Among down-stream effectors of the NGF receptor TrkA signaling pathway, reserpine treatment induced elevation of TrkA phosphorylation and reduction of ERK phosphorylation. In addition, in the NGF receptor $p75^{NTR}$ signaling pathway, the expression levels of $p75^{NTR}$ and Bcl-2 were enhanced in reserpine-treated Tg2576 mice compared with vehicle-treated mice, whereas the expression level of RhoA declined. Overall, these results suggest that reserpine can help relieve AD pathogenesis in Tg2576 mice through downregulation of $A{\beta}$-42 deposition, alteration of ${\gamma}$-secretase components, and regulation of NGF metabolism.

• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.3
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• pp.298-305
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• 2017

Atopic dermatitis is a chronic, relapsing inflammatory skin disease. This study aimed to investigate the therapeutic benefits of Aronia melanocarpa (AM) and Moringa oleifera seed extract (MO) on experimental atopic dermatitis. We examined the effects of AM or MO and their combination on 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis in BALB/c mice as well as tumor necrosis factor $(TNF)-{\alpha}$ and interferon $(IFN)-{\gamma}-stimulated$ HaCaT keratinocytes. Mice were orally treated with extract during repeated application of DNCB to shaved dorsal skin. Our results show that treatment with AM and MO in combination reduced histological manifestations such as epidermal hyperplasia and inflammatory cell infiltration. Furthermore, it significantly decreased skin thickness and serum immunoglobulin E (IgE) level compared to the AM or MO alone treated group. Combined extract of AM and MO suppressed expression of $TNF-{\alpha}/IFN-{\gamma}-induced$ T helper 2 (Th2) chemokines such as thymus and activation-regulated chemokine and macrophage-derived chemokine. To sum up, combination of AM and MO suppressed the inflammatory response and serum IgE as an indicator of several allergic diseases in DNCB-induced experimental atopic dermatitis and Th2 chemokine expression in HaCaT cells. This result suggests that combination of AM and MO could be a valuable strategy to improve atopic dermatitis.

• Radiation Oncology Journal
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• v.24 no.4
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• pp.280-284
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• 2006

$\underline{Purpose}$: To evaluate biological characteristics of neutron beam generated by MC50 cyclotron located in the Korea Institute of Radiological and Medical Sciences (KIRAMS). $\underline{Materials\;and\;Methods}$: The neutron beams generated with 15 mm Beryllium target hit by 35 MeV proton beam was used and dosimetry data was measured before in-vitro study. We irradiated 0, 1, 2, 3, 4 and 5 Gy of neutron beam to EMT-6 cell line and surviving fraction (SF) was measured. The SF curve was also examined at the same dose when applying lead shielding to avoid gamma ray component. In the X-ray experiment, SF curve was obtained after irradiation of 0, 2, 5, 10, and 15 Gy. $\underline{Results}$: The neutron beams have 84% of neutron and 16% of gamma component at the depth of 2 cm with the field size of $26{\times}26\;cm^2$, beam current $20\;{\mu}A$, and dose rate of 9.25 cGy/min. The SF curve from X-ray, when fitted to linear-quadratic (LQ) model, had 0.611 as ${\alpha}/{\beta}$ ratio (${\alpha}=0.0204,\;{\beta}=0.0334,\;R^2=0.999$, respectively). The SF curve from neutron beam had shoulders at low dose area and fitted well to LQ model with the value of $R^2$ exceeding 0.99 in all experiments. The mean value of alpha and beta were -0.315 (range, $-0.254{\sim}-0.360$) and 0.247 ($0.220{\sim}0.262$), respectively. The addition of lead shielding resulted in no straightening of SF curve and shoulders in low dose area still existed. The RBE of neutron beam was in range of $2.07{\sim}2.19$ with SF=0.1 and $2.21{\sim}2.35$ with SF=0.01, respectively. $\underline{Conclusion}$: The neutron beam from MC50 cyclotron has significant amount of gamma component and this may have contributed to form the shoulder of survival curve. The RBE of neutron beam generated by MC50 was about 2.2.