• Korean Journal of Remote Sensing
• /
• v.25 no.3
• /
• pp.233-242
• /
• 2009

This paper presents two different types of supervised classifiers such as support vector machine (SVM) and spectral angle mapper (SAM). The Compact Airborne Spectrographic Imager (CASI) high resolution aerial image was classified with the above two classifier. The image was classified into eight land use /land cover classes. Accuracy assessment and Kappa statistics were estimated for SVM and SAM separately. The overall classification accuracy and Kappa statistics value of the SAM were 69.0% and 0.62 respectively, which were higher than those of SVM (62.5%, 0.54).

• Geotechnical Engineering
• /
• v.14 no.4
• /
• pp.177-204
• /
• 1998

In the present study, a method of quasi-three dimensional stability analysis is proposed for a systematic design of the GRS-RW(Geosynthetic-Reinforced Soil Retaining Wall) system based on the postulated three dimensional failure wedge. The proposed method could be applied to the analysis of the stability of both the straight-line and cove-shaped are. As with skew reinforcements. Maximum earth thrust expected to act on the rigid face wall is assumed to distribute along the depth, and wall displacements are predicted based on both the assumed compaction-induced earth pressures and one dimensional finite element method of analysis. For a verification of the procedure proposed in the present study, the predicted wall displacements are compared with chose obtained from the RMC tests in Canada and the FHWA tests in U.S.A. In these comparisons the wall displacements estimated by the methods of Christopher et at. and Chew & Mitchell are also included for further verification. Also, the predicted wall displacements for the convex-shaped zone reinforced with skew reinforcements are compared with those by $FLAC_{3D}$ program analyses. The assumed compaction-induced earth pressures evaluated on the basic of the proposed method of analysis are further compared with the measurements by the FHWA best wall. A parametric stduy is finally performed to investigate the effects of various design parameters for the stability of the GRS-RW system

• Clinical Nutrition Research
• /
• v.12 no.3
• /
• pp.199-217
• /
• 2023

People with higher genetic predisposition to obesity are more susceptible to cardiovascular diseases (CVDs) and healthy plant-based foods may be associated with reduced risks of obesity and other metabolic markers. We investigated whether healthy plant-foods-rich dietary patterns might have inverse associations with cardiometabolic risk factors in participants at genetically elevated risk of obesity. For this cross-sectional study, 377 obese and overweight women were chosen from health centers in Tehran, Iran. We calculated a healthy plant-based diet index (h-PDI) in which healthy plant foods received positive scores, and unhealthy plant and animal foods received reversed scores. A genetic risk score (GRS) was developed based on 3 polymorphisms. The interaction between GRS and h-PDI on cardiometabolic traits was analyzed using a generalized linear model (GLM). We found significant interactions between GRS and h-PDI on body mass index (BMI) (p = 0.02), body fat mass (p = 0.04), and waist circumference (p = 0.056). There were significant gene-diet interactions for healthful plant-derived diets and BMI-GRS on high-sensitivity C-reactive protein (p = 0.03), aspartate aminotransferase (p = 0.04), alanine transaminase (p = 0.05), insulin (p = 0.04), and plasminogen activator inhibitor 1 (p = 0.002). Adherence to h-PDI was more strongly related to decreased levels of the aforementioned markers among participants in the second or top tertile of GRS than those with low GRS. These results highlight that following a plant-based dietary pattern considering genetics appears to be a protective factor against the risks of cardiometabolic abnormalities.

• Journal of Gifted/Talented Education
• /
• v.20 no.2
• /
• pp.595-619
• /
• 2010

This study examined the construct validity of a Korean translated version of the Gifted Rating Scales-School Form (GRS-S). Data were collected from five elementary schools in a metropolitan area and a midsize town in South Korea. Confirmatory factor analysis results indicated that the original factor structure (6-factor solution) fit the data collected from the teachers. However, the 6-factor solution did not fit the data collected from the parents. Thus, exploratory factor analysis was conducted for the parent data. The results showed that seven factors were extracted, and the factors explained 71.96% of the total variance. Unlike the original factor structure, some items of the academic ability scale were grouped with intellectual ability scale, and a creativity scale item and another academic ability scale item were an independent factor. The study outcomes provide preliminary support for a translated version of the GRS-S with elementary students in Korea. More detailed interpretations and implications of the results are discussed in the study.

• Journal of Korean Biological Nursing Science
• /
• v.25 no.1
• /
• pp.73-85
• /
• 2023

Purpose: This study focused on identifying the interaction effects of genetic and lifestyle-environmental factors on the development of type 2 diabetes mellitus (T2D). Methods: Study subjects were selected from the Korean Genome and Epidemiology Study (KoGES) from 2001 to 2014. Data on genetic variations, anthropometric measurements, biochemical data, and seven lifestyle factors (diet, physical activity, alcohol drinking, smoking, sleep, depression, and stress) were obtained from 4,836 Koreans aged between 40 and 59 years, including those with T2D at baseline (n = 1,209), newly developed T2D (n= 1,298) and verified controls (n = 3,538). The genetic risk score (GRS) was calculated by using 11 single-nucleotide polymorphisms (SNPs) related to T2D development and the second quartile was used as the reference category. A Cox proportional hazards regression model was used to evaluate the associations of GRS and lifestyle factors with T2D risk, controlling for covariates. Results: Multivariate regression analysis revealed that GRS was the strongest risk factor for T2D, and body mass index (BMI), smoking, drinking, and spicy food preference also increased the risk. Lifestyle/environmental factors that showed significant interactions with GRS were BMI, current smoking, current drinking, fatty food preference, and spicy food preference. Conclusions: Interactions between genetic factors and lifestyle/environmental factors were associated with an increased risk of T2D. The results will be useful to provide a new perspective on genetic profiling for the earlier detection of T2D risk and clues for personalized interventions, which might be more effective prevention strategies or therapies in individuals with a genetic predisposition to T2D.

• Genomics & Informatics
• /
• v.11 no.1
• /
• pp.46-51
• /
• 2013

Normal-karyotype acute myeloid leukemia (NK-AML) is a highly malignant and cytogenetically heterogeneous hematologic cancer. We searched for somatic mutations from 10 pairs of tumor and normal cells by using a highly efficient and reliable analysis workflow for whole-exome sequencing data and performed association tests between the NK-AML and somatic mutations. We identified 21 nonsynonymous single nucleotide variants (SNVs) located in a coding region of 18 genes. Among them, the SNVs of three leukemia-related genes (MUC4, CNTNAP2, and GNAS) reported in previous studies were replicated in this study. We conducted stepwise genetic risk score (GRS) models composed of the NK-AML susceptible variants and evaluated the prediction accuracy of each GRS model by computing the area under the receiver operating characteristic curve (AUC). The GRS model that was composed of five SNVs (rs75156964, rs56213454, rs6604516, rs10888338, and rs2443878) showed 100% prediction accuracy, and the combined effect of the three reported genes was validated in the current study (AUC, 0.98; 95% confidence interval, 0.92 to 1.00). Further study with large sample sizes is warranted to validate the combined effect of these somatic point mutations, and the discovery of novel markers may provide an opportunity to develop novel diagnostic and therapeutic targets for NK-AML.

• The Journal of Asian Finance, Economics and Business
• /
• v.8 no.11
• /
• pp.1-10
• /
• 2021

This paper compares the performance of Fama-French three-factor and five-factor models using a dataset of 20 Pakistani commercial banks for the period 2011 to 2020. We focus on an emerging economy as the findings from earlier studies on developed countries cannot be generalized in emerging markets. For empirical analysis, twelve portfolios were developed based on size, market capitalization, investment strategy, and growth. Subsequently, we constructed five Fama-French factors namely, R_M, SMB, HML, RMW, and CMA. The OLS regression technique with robust standard errors was applied to compare the predictive power of both the Fama-French models. Further, we also compared the mean-variance efficiency of the Fama-French models through the GRS test. Our empirical analysis provides three unique and interesting findings. First, both asset pricing models have similar predictive power to explain the expected portfolio returns in most cases. Second, our results from the GRS test suggest that there is no noticeable difference in the mean-variance efficiency of one asset pricing model over the other. Third, we find that all factors of both Fama-French models are statistically significant and are important for explaining the volatility of expected commercial bank returns in the context of Pakistan.

• Journal of Korean Academy of Nursing
• /
• v.17 no.3
• /
• pp.184-194
• /
• 1987

The purposes of this study were; 1) to gather data relevant to demographic features. major main management practices, and the level of impairment of the activities of daily living (ADL) of patients with back pain, 2) to test the sensitivity of the Korean Pain Rating Scale and the Graphic Rating Scales, and 3) to identify indirect indicators of back pain by analysing pain related-behaviors. The level of pain was measured by Korean Pain Rating Scale(KPRS) and Graphic Rating Scales(GRS) developed by the reserchers. The GRS consists of two dimensions; the pain intensity (sensory) and unpleasantness (affective) measures. Of the 1,650 diagnosed back pain patients, from January 4 through June 30, 1987 by visiting outpatients' clinics of orthopedic and neurosurgical departments at 11 university hospitals in different districts of Korea, 330 men and women patients were self-selected by responding to the mailed questionnaires. The results were summarised as follows: Male exceeded female patients in number and onset of back pain were more prevalent in the age groups of 20s and the 30s. The average duration of suffering from the pain were 11 months, sixty three (19.1%) of the subjects retired from their jobs, one third(36.7%) have teen hospitalized for the treatment of back pain. In two thirds(64.8%) of the cases pain was characterized as lower back pain. The average sleep hour was 6.8 hours per 24 hours and the average rest hour during the day was 3.3 hours. The mean percentage of pain measured by GRS was higher than that of KPRS. The level of sensory intensity as well as the affective level of pain measured by KPRS and GRS were not highly correlated (sensory intensity r=0.4986, affective r=0.5029) which indicated low discriminative power. On the other hand, intercorrelation between sensory and affective dimension measured by KPRS and GRS showed moderate interrelation(r=0.7247; r=0.7899). One-third(32.5%) of the subjects complied with the hospital prescribed treatment while the other one-third(31.5%) depended on self-remedy and traditional practices, and the last one-third did not imply any pain management practices. The following 6 pain-related behaviors such as length of hospitalization, rest hour during day hours, varieties of pain management practice implied, number of pain sites, need for ADL and discomfort accompanied by ADL revealed to be important indicators of back pain. An investigation of sociodemographic features of patients with back pain in a larger context, i.e. with bigger number of respondents is recommended. Tests for construct validity of KPRS, i.e. factor analysis is further recommended.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.16 no.11
• /
• pp.7367-7376
• /
• 2015

This study was investigate the effects of the magnetic field therapy applied to the acupuncture point on dysmenorrhea experienced by high school girls and to verify the possibility to use this therapy as an effective in-home nursing intervention. Data were collected from Feburary to April, 2006. The research procedure was that female students who visited in public health center had to fill in questionnaires with dysmenorrhea Grapic Rating Scale(GRS) and Adjective Labor Pain Rating Scale(ALPRS), the gauge of pain, before participating the experiment. And then each group was tested for 3 hours. Participants before and after applying magnetic treatment filled each questionnaires with dysmenorrhea GRS and ALPRS. The GRS points and ALPRS points in the experimental group, applied by Magnetic Field therapy on acupuncture point is lower than that in the comparison group. The above result has proved that the magnetic field therapy on acupuncture has an effect on the pain alleviation of dysmenorrhea of female students in high school. Therefore, propose this therapy to dysmenorrhea of female students. In this research, ALPRS indicated validity on dysmenorrhea, so for verifying validity, further research is necessary.

• Journal of Korean Neurosurgical Society
• /
• v.67 no.1
• /
• pp.60-72
• /
• 2024

Objective : Recently, robotic-assisted spine surgery (RASS) has been considered a minimally invasive and relatively accurate method. In total, 495 robotic-assisted pedicle screw fixation (RAPSF) procedures were attempted on 100 patients during a 14-month period. The current study aimed to analyze the accuracy, potential risk factors, and learning curve of RAPSF. Methods : This retrospective study evaluated the position of RAPSF using the Gertzbein and Robbins scale (GRS). The accuracy was analyzed using the ratio of the clinically acceptable group (GRS grades A and B), the dissatisfying group (GRS grades C, D, and E), and the Surgical Evaluation Assistant program. The RAPSF was divided into the no-breached group (GRS grade A) and breached group (GRS grades B, C, D, and E), and the potential risk factors of RAPSF were evaluated. The learning curve was analyzed by changes in robot-used time per screw and the occurrence tendency of breached and failed screws according to case accumulation. Results : The clinically acceptable group in RAPSF was 98.12%. In the analysis using the Surgical Evaluation Assistant program, the tip offset was 2.37±1.89 mm, the tail offset was 3.09±1.90 mm, and the angular offset was 3.72°±2.72°. In the analysis of potential risk factors, the difference in screw fixation level (p=0.009) and segmental distance between the tracker and the instrumented level (p=0.001) between the no-breached and breached group were statistically significant, but not for the other factors. The mean difference between the no-breach and breach groups was statistically significant in terms of pedicle width (p<0.001) and tail offset (p=0.042). In the learning curve analysis, the occurrence of breached and failed screws and the robot-used time per screw screws showed a significant decreasing trend. Conclusion : In the current study, RAPSF was highly accurate and the specific potential risk factors were not identified. However, pedicle width was presumed to be related to breached screw. Meanwhile, the robot-used time per screw and the incidence of breached and failed screws decreased with the learning curve.