• Title/Summary/Keyword: GPT2

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A CLINICAL STUDY OF THE OBESITY PATIENTS ACCORDING TO SASANG CONSTITUTION (Focusing on the physical views and diagnosis results) (비만환자(肥滿患者)의 체질적 특징(特徵)에 대한 임상적(臨床的) 고찰(考察))

  • Cho, Min-sang;Kho, Byung-hee;Song, Il-byung
    • Journal of Sasang Constitutional Medicine
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    • v.10 no.2
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    • pp.485-511
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    • 1998
  • In orther to find the characteristics of each constitution, the examine of Kyung Hee medical center was diagnosed constitution, and resulted body measures and diagnosis. That was considered and the results are as follows 1. The obese patients is that there are the best many people(91.0%) to Taeumin. The frequency of Taeumin group is more than Soyangin group and Soeumin group. The degree of obesity grade is the highest in Taeumin. 2. The systolic blood & diastolic blood pressure of obese patients did not show any significant differences. Only, the obesity patients is the higher than nomal examine, without regard to Sasang constitution. 3. The hypertensive frequency of obese patients is that Taeumin group is more than Soyangin group and Soeumin group. there is not show any significant differences. specially, the hypertension of Soyangin group is caused by an ascending of diastolic pressure. 4. Glucose value of obese patients did not show any significant differences. generally, the frequency of Taeumin group is more than Soyangin group and Soeumin group. The diabetes of obese patients is the highest in Taeumin. 5. The serum lipids of obese patients did not show any significant differences. Total cholesterol, Triglyceride value of Taeumin group is more than Soyangin group and Soeumin group. HDL-cholesterol of obese patients is that Taeumin group is more than Soyangin group and Soeumin group. 6. The frequency of hyperlipidemia is the highest in Taeumin. 7. GOT, GPT of obese patients did not show any significant differences, but GGT is higher in Taeumin than Soyangin & Soeumin group. 8. Uric acid of obesity patients did not show any significant differences between Sasang constitution, but the value of obese patients is higher than nomal examine. The abnomality of Uric acid is higher in Taeumin than the other constitutions. The frequency of abnomality is the highest in Taeumin females. 9. Arteriosclerosis frequency of obese patients did not show any significant differences, the frequency of Sasang constitution is higher in Taeumin than Soyangin & Soeumin group. 10. Hemoglobin of obese patients did not show any significant differences, but Hematocrit is higher in Soyangin than Taeumin & Soeumin group. Anemia of obese patients did not show any significant differences. The frequency of anemia is higher in the females than the males. 11. BUN, creatinine of obese patients did not show any significant differences.

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Comparison of the Total Antioxidant Status and Usual Dietary Intake in Normal and Overweight Males (정상체중군과 체중과다군 남자에서 혈중 총항산화능과 평소 식이섭취 상태에 관한 연구)

  • 김순경;박영숙;변광의
    • Korean Journal of Community Nutrition
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    • v.5 no.4
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    • pp.633-641
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    • 2000
  • This study was conducted to measure the difference in the total antioxidant status(TAS) of overweight and normal weight adults, and to investigate the correlation between TAS and the nutrient intake. Anthropometric parameter, TAS, biochemical parameters and dietary intake were measured in the normal weight group(n=17, BMI 20-25, obesity index 90-110%, body fat 16-20%) and overweight group(n=13, BMI > 25, obesity index > 120%, body fat > 25%) among Korean young males. The TAS of the overweight group was significantly higher than that of the normal weight group(p < 0.01). Among biochemical parameters, the average uric acid concentration of the overweight group was significantly higher(p < 0.05) compared to that of the normal weight group indicating, the uric acid concentration reflects TAS. Usual dietary intake showed that the intakes of Ca and vitamin B$_2$, are below RDA. The average intake of vitamin C in the overweight group was significantly lower than that in the normal group(p < 0.05). There was no difference in the intake of carotene and vitamin E between groups. The diet quality of both groups was satisfactory. The result of the correlation analysis on TAS, the uric acid concentration, and the measured indexs are as follows : In the overweight group, TAS was negatively correlated with alchol drinking, and uric acid concentration was positively correlated with BMI, obesity index, and TAS. In conclusion, TAS was significantly higher in the overweight group than that of the normal group, although no association was found with nutrient intakes. Serum uric acid showed a positive relationship with TAS indicating, it is a possible determinant of the antioxidant capacity.

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Health effects on workers and actual exposure of VOCs in the nail shops (네일샵 종사자의 휘발성유기화합물 노출실태와 건강에 미치는 영향)

  • Kim, Nan-Hee;Min, Kyoung-Woo;Cho, Gwang-Woon;Seo, Dong-Ju;Im, Kyeong-Hun;Jeung, Won-Sam;Cho, Young-Gwan;Yang, Jin-Seok
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.27 no.1
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    • pp.59-69
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    • 2017
  • Objectives: The objective of this study is to evaluate the exposure of VOCs and effects of the chemicals on the nail technicians whose works in a nail shop. Methods: For four month from May to August in 2016, we measured twenty-two kinds of VOCs in ten nail shops and carried out health examinations on thirty-four workers in there. Results: The TVOC concentration in indoor air of nail shops is $0.487mg/m^3$ at a minimum and $33.236mg/m^3$ at a maximum where it consists of 70.5% of Ketones, 25.4% of Alcohols, 2.6% of Esters, 0.8% of Aldehydes and 0.7% of Aromatics. The VOCs concentration during nail art works shows an increase in average ratio 1.8 compared to the concentration of indoor air quality and also the concentration of Isopropanol rose with 3.2 of the highest ratio. The results of Spearman correlation between TVOC concentration in indoor air and environmental factor was like that has significance level of correlation(${\rho}$<0.05, r=0.682) in case of number of customers per day, but the other factors were not meaningful in correlation. Correlation between VOCs and medical check-up items was like that has positive significance level(${\rho}$<0.01, r=0.638) between isopropanol and GPT, but the others have not meaningful. The exposure level of VOCs was not exceed the criteria exposure level 1 of working environment measuring method which announced by labor ministry in all ten nail shop indoor air quality. Conclusions: In this study although it was not significant correlation between harmful substances and medical check-up items in the nail shop indoor air quality, it is necessary to do more ventilation and to install exhaust facilities because of existing high VOCs concentration in the nail shop indoor air.

The Education Model of Liberal Arts to Improve the Artificial Intelligence Literacy Competency of Undergraduate Students (대학생의 AI 리터러시 역량 신장을 위한 교양 교육 모델)

  • Park, Youn-Soo;Yi, Yumi
    • Journal of The Korean Association of Information Education
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    • v.25 no.2
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    • pp.423-436
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    • 2021
  • In the future, artificial intelligence (AI) technology is expected to become a general-purpose technology (GPT), and it is predicted that AI competency will become an essential competency. Several nations around the world are fostering experts in the field of AI to achieve technological proficiency while working to develop the necessary infrastructure and educational environment. In this study, we investigated the status of software education at the liberal arts level at 31 universities in Seoul, along with precedents from domestic and foreign AI education research. Based on this, we concluded that an AI literacy education model is needed to link software education at the liberal arts level with professional AI education. And we classified 20 AI-related lectures released in the KOCW according to the AI literacy competencies required; based on the results of this classification, we propose a model for AI literacy education in the liberal arts for undergraduate students. The proposed AI literacy education model may be considered as AI·SW convergence to experience AI along with literacy in the humanities, deviating from the existing theoretical and computer-science-based approach. We expect that our proposed AI literacy education model can contribute to the proliferation of AI.

Long-tenn Evaluation of Extruded Pellet Diets Compared to Raw Fish Moist Pellet Diet for Growing Flounder, Paralichthys olivaceus (넙치 미성어 건조 배합사료 및 습사료의 장기사육 평가)

  • Kim Kang-Woong;Kang Yong Jin;Kim Kyong-Min;Lee Hae Young;Kim Kyoung-Duck;Bai Sungchul C.
    • Journal of Aquaculture
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    • v.18 no.4
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    • pp.225-230
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    • 2005
  • This experiment was conducted to compare the effects of extruded pellets and raw fish-based pellet on olive flounder Paralichthys. olivaceus. Six diets were prepared for this study: two formulated extruded pellets (FEP1 & FEP2), three commercially available extruded pellets (CEP1, CEP2 & CEP3) and moist pellet (MP). Weight gain offish fed FEP1 and CEP3 were significantly higher (P<0.05) than those of fish fed FEP2, CEP1, CEP2 and MP, while that of fish fed MP was not significantly different (f<0.05) from those of fish fed the FEP2, CEP1 and CEP2. Feed efficiency of fish fed CEP2 was significantly lower (P<0.05) than those of fish fed FEP1, FEP2, CEP1, CEP3 and MP. There was no significant difference in protein efficiency ratio and hepatosomatic index between fish fed FEP1 and CEP3, and among fish fed FEP2, CEP1 and CEP2. There was no significant difference in condition factor among fish fed the FEP1 and CEP3, and between fish fed FEP2, CTP1 and MP. However, fish fed MP had a lower survival rate than fish fed the other five EP These results suggest that diet FEPl could be developed to replace MP for the owing stage of flounder without adverse effects on growth performance.

Hepatoprotective effect of Hippocampus abdominalis hydrolysate (Hippocampus abdominalis 유래 단백질 가수분해물의 간 보호 효과)

  • Son, Moa;Moon, Jun young;Park, Sanggyu;Cho, Moonjae
    • Journal of Applied Biological Chemistry
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    • v.59 no.3
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    • pp.265-271
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    • 2016
  • Recently, liver damage contributes to big percentage of the morbidity and mortality rates worldwide. Excessive intake of alcohol is one of the major causes of liver injury. When liver injury is repeated and becomes chronic, it leads to development of fibrosis and cirrhosis. In the liver, TGF-${\beta}$ is a profibrogenic cytokine, which participates in various critical events cause liver fibrosis. Seahorse (Hippocampus abdominalis) is a common traditional Chinese medicine and has been widely used for centuries. Seahorse has been known to have a variety of bioactivities, such as anti-oxidant, anti-fatigue, and anti-tumor. Peptide is one of the main compounds of seahorse. In this study, we isolated enzymatic hydrolysate from seahorse H. abdominalis by alcalase hydrolysis and investigated the effect of the hydrolysate on liver injury. In the present in vitro studies, the hydrolysate increases cell viability of Chang cells and protects Huh7 cells from ethanol toxicity. In addition, the hydrolysate inhibits TGF-${\beta}$-induced responses. In vivo studies show that the pretreatment of hydrolysate reduces alcohol-induced increases of serum Glutamic oxaloacetic acid transaminase and Glutamic pyruvate transaminase activities and increases liver weight and body weight. These results suggest that seahorse may have a hepatoprotective effect.

Effect of Calcium and Magnesium on the Lipid and Mineral Composition of Serum and Tissues in Cholesterol-fed Rats (칼슘과 마그네슘이 콜레스테롤 첨가식이로 사육한 흰쥐의 혈청과 조직중 지질 및 무기질에 미치는 영향)

  • Chang, Soon-Hee;Cho, Soo-Yeul;Park, Mi-Lee
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.17 no.2
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    • pp.176-183
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    • 1988
  • This experiment was undertaken to investigate the effect of caluium and magnesium on the lipid and mineral composition of serum and tissues in cholesterol-fed rats. GOT of serum was significantly decreased in normal Ca and high Mg supplemented group. Serum cholesterol level was significantly decreased in high Mg supplemented group, whereas that of low Mg supplemented group was significantly increased. Content of total lipid in liver were significantly decreased by supplementation with high calcium of magnesium. However, the content of cholesterol was not affected by supplementation with high calcim and that of low Mg supplemented group was significantly increased. In fatty acid composition of liver, he the order of fatty acid content is as following; oleic acid (18:1), stearic acid(18:0), and palmitic acid(16:0). Levels of Ca, Mg, K and Cu in liver were significantly affected by dietary calcium and magnesium levels. The Mg level of kidney was decreased but Cu level was elevated in cholesterol supplemented group. Levels of Ca, Mg, and Zn in serum were significantly elevated by supplementation with high calcium or magnesium.

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Modulation of obesity by Gyeongshingangjeehwan18 in ob/ob mice (Ob/Ob 마우스에서 경신강지환(輕身降脂丸)18의 비만조절)

  • Yoon, Ki-Hyeon;Lee, Hee-Young;Jung, Yang-Sam;Seo, Bu-Il;Park, Gyu-Ryeol;Yoon, Mi-Chung;Shin, Soon-Shik
    • The Korea Journal of Herbology
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    • v.25 no.3
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    • pp.1-9
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    • 2010
  • Objectives : This study was undertaken to verify the effects of Gyeongshingangjeehwan18 (GGEx18) on obesity using ob/ob male mice. Methods : Eight-week old mice (wild-type C57BL/6J and ob/ob) were used for all experiments. Wild-type C57BL/6J mice were used as lean control and obese ob/ob mice were randomly divided into 5 groups: obese control, GGEx15, GGEx16, GGEx17, and GGEx18. After mice were treated with several kinds of GGEx for 11 weeks, body weight gain, feeding efficiency ratio, plasma lipid and glucose metabolism. Results : 1. Compared with obese controls, GGEx-treated mice had lower body weight gain and feeding efficiency ratio, the magnitudes of which were prominent in GGEx16 and GGEx18. 2. Consistent with their effects on body weight gain, GGEx16 and GGEx18 not only decreased plasma triglycerides levels, but also increased HDL-cholesterol concentration. 3. CT analysis revealed that visceral fat areas were decreased in all treatment groups compared with obese control mice. The decrease in visceral fat area was prominent in GGEx16 and GGEx18, although they were not statistically significant. 4. The size of adipocytes were significantly decreased by GGEx18, whereas the adipocyte number per unit area was significantly increased, suggesting that GGEx18 decreased the number of large adipocytes. Hepatic lipid accumulation was decreased by GGEx16 and GGEx18, and the inhibitory effect was most effective in GGEx18. 5. Plasma GOT and GPT concentrations were significantly lower following GGEx16 and GGEx18 treatment compared with obese controls. Organ weights were not changed by GGEx treatment, indicating GGEx do not show any toxic effects. Conclusions : These results suggest that GGEx may regulate obesity. Of the 4 compositions, GGEx18 seems to be most effective in improving obesity and lipid disorders.

A Study on the effects of Ginseng Radix extract on rat with nephrotoxicity (인삼(人蔘)이 Cyclosporin A로 유발(誘發)된 백서(白鼠)의 신손상(腎損傷)에 미치는 영향(影響))

  • Seo, Ho-Suk;Han, Yang-Hi;Park, Jong-Hyung;Jun, Chan-Yong;Kim, Dong-U;Park, Se-Gi;Lee, Chung-Jung-Hye;Go, Jae-Chul;Choi, You-Kyung;Baek, Eun-Gi;Hong, Ui-Sil;Park, Ji-Yun;Go, Seung-Hi
    • The Journal of Internal Korean Medicine
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    • v.22 no.1
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    • pp.45-52
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    • 2001
  • Purpose : This study is to find out the Ginseng Radix extract on rats nephrotoxicity when the rates were induced by Cs A. Methods : The experimental animals were divided into 3 groups and treated as follows: nothing was given to Sample A, Sample B was given normal saline after an I.V. injection of Cs A, and Sample C was given Ginseng Radix extract after a Cs A injection. The groups were observed for 14 days. After the prescription of the medicines, the following levels were tested: serum BUN, creatinine, total protein, sodium, potassium, and chloride ions. Results : 1. Changes in serum level. The levels of GPT, GOT, and BUN were significantly reduced in the experimental group when compared with those of the control group. The total protein level showed significant elevation when compared with those of the control group. The chloride level in the serum in the sample group was insignificantly reduced. The creatinine level was insignificantly increased. The Potassium level decreased, mildly. The Sodium and The Potassium levels in the serum in the sample group showed insignificantly lower levels than those of the control group. 2. Changes in the urine level. Urine specific gravity showed a significant increase, on the 14th day, in the experimental group when compared with that of the control group. The urinary ceatinine levels showed and insignificant increase, followed by an insignificant decrease. Conclusion : It can be inferred that Ginseng Radix may improve nephrotoxicity and hepatoxicity in rats when induced by Cyclosporin A.

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Analysis of Productivity of a Polyculture Container for Suspended Rearing of Abalones and Sea cucumbers (전복과 해삼 수하양식을 위한 복합사육기의 생산력 분석)

  • Nam, Myung-Mo;Lee, Chu;Moon, Tae-Seok;Kim, Su-Kyung;Hwang, Jin-Wook
    • The Korean Journal of Malacology
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    • v.27 no.4
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    • pp.323-330
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    • 2011
  • We have developed a polyculture container which is preferable for rearing of abalones and sea cucumbers in East Sea. To test the rearing capacity of the polyculture container, 50, 75 and 100 sea cucumbers ranging from the body length of 7-9 cm were cultured in three containers including 500 abalones with the shell length of about 5 cm, respectively. It was revealed that preferable density for sea cucumbers was 52-72 individuals in the polyculture container. Glutamate oxaloacetate transaminase and glutamate pyruvate transaminase were analyzed with Reflotron kit to investigate the health degree of abalones in two polyculture containers including 300 and 500 abalones with the shell length of about 5 cm. Glutamate oxaloacetate transaminase has been an important tool to know myocardial infarction, disease of liver, and destruction of muscle. Next experiment was conducted to determine the effects on growth of abalones and sea cucumbers in polyculture container. Experimental findings, RNA/DHA ratio, DNA and RNA contents (ug/mg) were not significantly different among all groups. The results imply that the method of polyculture can be rearing with sea cucumber without growth retardation of abalone. Production ability between polyculture container and the container used in south sea were carried out using suspended culture method during 8months. It was revealed that abalones and sea cucumbers are faster growing in polyculture container than in container used in south sea. Therefore, polyculture container is considered more appropriate for the abalones and sea cucumbers culture in East Sea.