• 한국어병학회지
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• 제3권2호
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• pp.81-91
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• 1990

평균체중(平均體重) 30 g의 향어에 과산화물가(過酸化物價) 98 meq/kg된 배합사료(配合飼料)를 4개월간(個月間) 투여(投與)한 결과(結果) 이들 향어의 간장(肝臟), 비장(脾臟), 신장(腎臟)에는 많은 ceroid가 침착(沈着)되었다. 이를 제거(除去)하기 위하여 glutathione을 첨가(添加)한 사료(飼料)를 투여(投與)하여 그 치료효과(治療效果)를 실험(實驗)하였다. 향어 1kg당 glutathione 유효성분(有效成分)을 1일(日) 3mg 및 6mg 섭취시키고 10일(日) 및 20일(日) 후(後)에 검사(檢査)한 결과(結果) 20일간(日間) 투여(投與)하면 치료효과(治療效果)가 뚜렷함을 알았다. Glutathione을 6 mg, 20일간(日間) 투여(投與)한 향어의 혈액성상(血液性狀)은 hematocrit 값, 총단백질량(總蛋白質量), 총(總) cholesterol량(量), glucose 값이 정상(正常)과 근사(近似)하였으며 비정상치(非正常値)였던 GOT, GPT 값은 정상치(正常値)로 향하여 감소(減少)되었다.

• 동의생리병리학회지
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• 제19권1호
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• pp.114-118
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• 2005

The purpose of this study was to investigate the possibility of Inonotus obliquus as an functional resource. To assess the effects of Inonotus obliquus in culturing method by using unpolished rice in 15non-insulin dependent diabetes mellitus persons, we examined changes of hematological and chemical variables, DM indices content in serum during the Inonotus obliquus supplementation. GOT, GPT concentrations were significantly decreased. But TIBC content was significantly increased. Fasting glucose level during Inonotus obliquus supplementation was decreased respectively. These results show that modest dose of Inonotus obliquus in culturing method by using unpolished rice supplementation can decrease fasting blood glucose level without any changes in health indices and nutrition status of the non-insulin dependent diabetes mellitus person. These results indicated that Inonotus obliquus in culturing method by using unpolished rice diet is effective therapeutic regimen for the control of metabolic derangements in diabetes mellitus. Also, the results imply that Inonotus obliquus in culturing method by using unpolished rice can be used as possible functional food materials. However, large amounts of Inonotus obliquus in culturing method by using unpolished rice showed be used cautiously application.

• Journal of Nutrition and Health
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• 제18권4호
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• pp.318-327
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• 1985

This study was designed to investigate the effect of early protein undernutrition of rats on later susceptibility to lead poisoning. Weanling rats, weighing about 55 grams, were malnourished by feeding low protein diets ( 12% and 5% casein diet ) during the four weeks of protein deprivation period. For the following 5 weeks, the malnourished rats were fed with 25% casein diet as rehabilitation diet. After the rehabilitation period, all rats were fed with 25% casein diet and the drinking water containing 2000ppm-Pb during the four weeks. The results obtained were as follows ; 1 ) Feed intake, body weight gain and food efficiency ratio were reduced in all rats exposed to lead, especially in rats fed with 5% casein diet during the four weeks of weanling period. 2 ) Enlargement of kidney and spleen were observed in all rats exposed to lead and were more remarkable in rats fed with 5% casein diet. 3 ) In rats exposed to lead, activity of serum glutamic oxaloacetic transaminase ( S- GOT ) was significantly increased by increasing the degree of early protein deprivation, whereas hematocrit value was significantly decreased. Activity of serum glutamic pyruvic transaminase ( S- GPT ) was shown a tendency to increase by increasing the degree of early protein deprivation, but the difference was not significant. 4) In rats exposed to lead, the amount of lead accumulation in kidney was increased by increasing the degree of early protein deprivation. The significant increase was shown in rats fed with 5% casein diet during the four weeks of weanling period. The results of the experiment suggest that early protein undernutrition, even after some period of rehabilitation, may enhance the later susceptibility to lead poisoning.

• 한국가금학회:학술대회논문집
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• 한국가금학회 2006년도 제23차 정기총회 및 학술발표회
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• pp.66-68
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• 2006

This experiment was conducted to study the effects of medicinal plant extract on performance in broiler chickens. A total of eight hundred forty, 1-d-old broiler chicks(Ross) were randomly allocated to 7 treatments with 4 replicates of 30 birds per replicate. The treatments were negative control (NC, diets without antibiotics), positive control (PC, diets with-containing antibiotics), Schisandrae fructus (T1), Scutellariae radix (T2), Camellia sinensis (T3), Artemisia capillaris (T4) and mixed medicinal plants (T5) extracts added to drinking water. The final body weight, body weight gain and feed conversion rate were significantly improved in all treatments compared to NC (P<0.05). No significant differences were observed in the relative weights of liver, spleen, pancreas, bursa of Fabricius and intestinal tract among the groups. The relative lengths of duodenum, jejunum and ileum were significantly decreased in PC compared with other groups (P<0.05). No significant differences were observed in the cecal microflora. The contents of triacylglycerol (TG), blood urea nitrogen (BUN), glutamic-oxaloacetic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) in blood serum were not significantly influenced. The concentration of cholesterol in blood serum was significantly decreased in all treated groups as compared to those of the control (P<0.05). There was no difference in the components of leukocytes and erythrocytes among the groups.

• 대한지역사회영양학회지
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• 제5권1호
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• pp.13-22
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• 2000

The study was curried out to collect information to establish a framework for nutrition education for the prevention of chronic degenerative disease. We analyzed differences in diet quality, food habits and health status of workers by work condition. Anthrometric parameters of height, weight and body fat were measured and biochemical parameters including glucose, total cholesterol, GOT, GPT and hemoglobin were determinded for 194 subjects. To assess the nutrient intake and diet quality of workers, dietary intake was measured by the day 24-hour recall method, Average daily nutrient intake, except for phos-phorous and vitamin C was lower than Korean RDA. The obesity related behavior score was significantly better in laborers than in office workers, while chronic degenerative diseases related to food habit score was significantly better in laborers than in office workers, while chronic degenerative diseases related to the food habit score was beet in offices workers than in laborers. Blood pressure, blood glucose levels were significantly higher in laborer than in office workers. Dietary variety score (DVS) food composition group score(FCGS), mean adequacy ratio(MAR) of office worker were better than those of labor workers. When diet quality was evaluated by FCGS(food composition group score) 16.0% of the subjects acquired 5 points and 14.4% of the subjects acquired 2 points.　MAR and INQ showed a significantly positive correlation with DVS and FCGS . This results indicated that the onset possibility of hypertension and diabetes mellitus among chronic degenerative disease was higher in laborers than in office workers, while the onset possibility of obesity was higher in office workers than in laborers. In conclusion the overall diet quality of office workers is betters than that of laborers, therefore, nutrition education for prevention of chronic degenerative disease of industrial workers needs to be more focused on the improvement of the health status of laborers.

• Nutritional Sciences
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• 제8권2호
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• pp.133-139
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• 2005

Objective: The purpose of this study was to determine serum antioxidant nutrients and the relationship between serum antioxidants and risks of chronic diseases in obese Korean children Methods: Normal weight Korean school children (0=170), mean age of 11.5$\pm$1.5, and obese (body fat mass > $28\%$) children (0=176), mean age of 11.0$\pm$1.8, were recruited Fat mass ($\%$) was determnined by Bioelectrical Impedance (BEI), and body mass index (BMI) was calculated Fasting blood was collected to measure serum antioxidant nutrients, vitamin A, vitamin E and zinc. Serum lipid profiles including total cholesterol (TC), high density cholesterol (HDL) and triglyceride (TG), and blood glucose, glutamic oxaloacetic transaminase (GOT), and glutamic pyruvic transaminase (GPI) were also determined. Differences in serum blood measurements between obese and normal children were assessed by independent t test. Pearson's correlation analysis was used to determine the relationship between variables. Results: Blood glucose, GPT, total cholesterol, and triglycerides concentrations were significantly higher among obese boys, compared to normal boys (p<005). Significantly lower concentrations of serum vitamin E, after adjustment for TG and TC, was shown in obese boys (0.26 mg/mg) and obese girls (0.31 mg/mg), compared to normal boys (0.36 mg/mg) and girls (0.38 mg/mg) (p<0.05). Fat mass ($\%$) was negatively con-elated with serum vitamin A and vitamin E. Conclusion: Obese Korean children showed insufficient serum vitamin E concentration and increased risk for diabetes, atherosclerosis, and liver disease. Since lower vitamin E concentration was negatively con-elated with atherogenic index, improved vitamin E status in children may decrease the risk of atherosclerosis later in life.

• Journal of Acupuncture Research
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• 제24권5호
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• pp.53-66
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• 2007

Objectives : The purpose of this study is to observe the antioxidant effect of electroaupuncture at TE5 on the rats that were given AAPH(50mg/kg) everyday. Methodes : The Rats were given AAPH(50mg/kg) in abdominal cavity everyday for one week. $TE_5-NR$ group were treated by acupucture on left $TE_5$ for 15min. $TE_5-EA$ group were treated by electroacupucture on left $TE_5$ for 15min. The author observe several changes of rats. First, it is change of rat weight. Second, it is change of Liver index. Third, it is changes of albumin, total bilirubin, LDL-cholesterol, LDH, Glucose, GOT, GPT. Fourth, it is changes of SOD & Catalase activity, Glutathione & NO & MDA concentration. Fifth, it is change of tissue. Results: 1. In the $TE_5-EA$ group, the live index was decreased significant compared with control & holder group. 2. In the $TE_5-EA$ group, the albumin level were increased significant compared with control & holder group, LDL-cholesterol, GOT level were decreased significant compared with control & holder group. 3. In the $TE_5-EA$ group, the SOD activity, Catalase activity were increased significant compared with control group, Glutathione level was increased significant compared with control & holder, sham-EA, $TE_5-NR$ group, NO and MDA concentration were decreased significant compared with control group.

• 한방재활의학과학회지
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• 제24권4호
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• pp.61-70
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• 2014

Objectives The purpose of this study was to investigate the characteristics in obesity classification group of college students having health checkup by analyzing their BMI and blood test and determine the association between factors contributing to obesity and obesity according to BMI. Methods A group of 2992 test subjects took their medical examination and their body composition, height, weight, blood pressure were measured and blood test was done. With these results we diagnosed obesity, and analysed relationship between obesity and cholesterol, triglyceride, LDL (low density lipoprotein)-cholesterol, HDL (high density lipoprotein)-cholesterol, liver function, renal function and blood pressure. Results 1. Overweight individuals showed high total cholesterol, LDL-cholesterol, triglyceride, GOT (glutamic oxalacetic transaminase), GPT (glutamic pyruvate transaminase), Urea-nitrogen, Creatinine and low HDL-cholesterol. 2. BMI showed a significant association with other factors. BMI has a negative correlation with sex and HDL-cholesterol. BMI had positive correlations with other factors. 3. There was no relation between BMI and sex. Those six factors, liver function, cholesterol, blood pressure, kidney function, neutral fat, and blood sugar were related to BMI. Conclusions There was a significant relation between college students' BMI and their liver function, cholesterol, blood pressure, kidney function, neutral fat, and blood sugar. The diseases related to liver function, cholesterol, blood pressure, kidney function, neutral fat, and blood sugar were clearly associated with obesity.

• 대한영양사협회학술지
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• 제7권4호
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• pp.331-348
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• 2001

The purpose of this study was to obtain basic data for nutrition education of the children in a health promoting elementry school. The data was collected by a questionaire of food habits, and anthropometric measurement and biochemical test in comparison with obesity index. The study subjects were boys and girls aged 10 to 12 years who participated in the “99 Children Nutrition Camp”. The average obesity index was 1.7$\pm$21.6% in boys and -11.4$\pm$12.6% in girls. After school, major leisure items were significnatly different by gender but both boys and girls played mainly computer game. In concern for body image and eating habits, girls had more concern and girls had attempted weight control more than boys. 80.2% of subjects had prejudice for special food, especially, all subjects in the severely underweight group had prejudice. But this tendency was significantly decreased with the increasing obesity index. The lowest preferency was for vegetables(64.4%). The tendency of prejudice of subjects was higher whose mother are thirties than those of subjects whose mother are in fourties. The serum GOT and GPT values were significantly higher in overweight and obese group than the other groups. The only serum T-chol was significantly higher in boys than in girls. The number of risk factors related to coronary heart disease(CHD) based on coresponding criteria of TG, T-chol, HDL-chol, and LDL-chol was not increased significantly with the degree of obesity index. The results indicated the need of nutritional management for the children. At a point of view, to educate children early who are able to change food habits and life-styles means to help heathy growth and to deliver up heathy adults. Active nutrition education for both children and mothers will be recommended with joint participation of nutritionists in community public health center and elementary school.

• 대한한방내과학회지
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• 제16권2호
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• pp.1-8
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• 1995

Effects of sosihotangganogyong on the activity of serum transferase and hepatic lipid peroxide in mice with $CCl_4$ solution were determined. The activity of ALT showed a high value in the mice with $CCl_4$, however in the mice with sosihotang and sosihotangganogyong, these values showed a tendency to rapid recovery compared with those of the mice with $CCl_4$ only and the activity of ALT in the group of sosihotang and sosihotangganogyong showed a low values compared with $CCl_4$ only group on the 21 days after treatment. On the 21 days after treatment, the activities of glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT) and lactic dehydrogenase (LDH) in the mice with sosihotang and sosihotangganogyog were similar to those of control group, however these values of $CCl_4$ only group showed a high values compared with those of other groups. The value of hepatic lipid peroxide in the mice with sosihotang and sosihotangganogyong showed a tendency to rapid decrease and recovery compared with those of $CCl_4$ only group and on the 21 days after treatment, this value showed a similar to those of control group. The activity of serum transferase and the value of hepatic lipid peroxide in the mice with sosihotngganogyong showed a tendency to decrease compared with those of sosihotang group, however these values showed a no significantly deference. Results from this study indicated that the sosihotagganogyong can effectively improve the recovery of liver function in mice with $CCl_4$.